The search for a solution to senile cataracts. Proctor lecture.

Theory of Transparency of the Eye

1971 • 876 citations

Short-range order of crystallin proteins accounts for eye lens transparency

1983 • 735 citations

Hydrogen peroxide and human cataract

1981 • 497 citations

Selective oxidation of cysteine and methionine in normal and senile cataractous lenses.

1980 • 299 citations

X-ray analysis of the eye lens protein γ-II crystallin at 1·9 Å resolution

1983 • 297 citations

Cross-Linking of Lens Crystallins in a Photodynamic System: A Process Mediated by Singlet Oxygen

1980 • 204 citations

Formation of N′-formylkynurenine in proteins from lens and other sources by exposure to sunlight

1971 • 181 citations

Studies on the Oxidation of Cysteine to Cystine in Lens Proteins During Cataract Formation*

1951 • 177 citations

On the presence and mechanism of formation of heavy molecular weight aggregates in human normal and cataractous lenses

1973 • 162 citations

Disulfide-linked high molecular weight protein associated with human cataract.

1978 • 156 citations

The role of glutathione metabolism in the detoxification of H2O2 in rabbit lens.

1982 • 109 citations

H2O2-induced uncoupling of bovine lens Na+,K+-ATPase.

1983 • 108 citations

Protein synthesis in the core of calf lens

1968 • 103 citations

Distribution of protein within the normal rat lens.

1969 • 101 citations

Age-dependent changes in the molecular size of human lens proteins and their relationship to light scatter.

1974 • 92 citations

The concentration and localization of heavy molecular weight aggregates in aging normal and cataractous human lenses

1975 • 91 citations

The human lens

1972 • 87 citations

Human lens membrane: Comparison of major intrinsic polypeptides from young and old lenses isolated by a new methodology

1979 • 81 citations

Racemization in human lens: evidence of rapid insolubilization of specific polypeptides in cataract formation.

1978 • 80 citations

Age-dependent changes in the structure of alpha crystallin.

1971 • 73 citations

Gamma-crystallin, a major cytoplasmic polypeptide disulfide linked to membrane proteins in human cataract

1981 • 60 citations

Biochemical evidence for membrane disintegration in human cataracts.

1981 • 59 citations

High molecular weight protein from human lenses

1976 • 55 citations

Sulfur oxidation in selected human cortical cataracts and nuclear cataracts

1980 • 51 citations

Evidence for a free radical mechanism in aging and u.v.-irradiated ocular lenses

1977 • 48 citations

Quantitative Biomicroscopy of Lens Light Back Scatter

1974 • 46 citations

The binding of photo-oxidized tryptophan to a lens gamma-crystallin

1973 • 37 citations

Transformation of alpha-crystallin polypeptide chains with aging.

1974 • 35 citations

Effect of magnesium ions on the high-affinity binding of eosin to the (Na+ + K+)-ATPase

1983 • 29 citations

Aggregation of a-crystallin and its possible relationship to cataract formation.

1972 • 29 citations

A Preliminary Study of the Dynamic Aspects of Age Dependent Changes in the Abundances of Human Lens Polypeptides

1979 • 21 citations

The localization of a 43K polypeptide in normal and cataractous lenses by immunofluorescence

1981 • 17 citations

Determination of the solvent accessibility of specific aromatic residues in gammacrystallin by photo-CIDNP NMR measurements

1984 • 12 citations

Some Aspects of Human Lens Metabolism: Glycolysis and Protein Synthesis

1976 • 7 citations

Studies on Lens Proteins II.

1979 • 7 citations