X-ray analysis of the eye lens protein γ-II crystallin at 1·9 Å resolution

A semi-empirical method of absorption correction

1968 • 7,409 citations

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

A graphics model building and refinement system for macromolecules

1978 • 1,858 citations

Theory of Transparency of the Eye

1971 • 876 citations

Protein crystallography

1977 • 713 citations

Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor

1974 • 548 citations

β-Sheet topology and the relatedness of proteins

1977 • 541 citations

Gene duplications in the structural evolution of chymotrypsin

1979 • 501 citations

The treatment of errors in the isomorphous replacement method

1959 • 497 citations

Conformation of twisted β-pleated sheets in proteins

1973 • 487 citations

Structural proteins of the mammalian lens: A review with emphasis on changes in development, aging and cataract

1976 • 482 citations

Excited state chemistry of aromatic amino acids and related peptides. III. Tryptophan

1975 • 435 citations

The molecular structure and stability of the eye lens: X-ray analysis of γ-crystallin II

1981 • 432 citations

The probability distribution of X-ray intensities

1949 • 406 citations

The matching of physical models to three-dimensional electron-density maps: A simple optical device

1968 • 313 citations

The accuracy of electron-density maps in X-ray analysis with special reference to dibenzyl

1949 • 243 citations

Mechanisms of Cataract Formation in the Human Lens

1981 • 239 citations

The distribution of phase angles for structures containing heavy atoms. II. A modification of the normal heavy-atom method for non-centrosymmetrical structures

1959 • 231 citations

Representation of phase probability distributions for simplified combination of independent phase information

1970 • 178 citations

CHAINS OF ALTERNATING SULFUR AND π‐BONDED ATOMS IN EIGHT SMALL PROTEINS

1978 • 165 citations

On the relative scaling of X-ray photographs

1965 • 154 citations

On the cysteine and cystine content of proteins

1977 • 153 citations

Studies on γ-crystallin from calf lens

1964 • 151 citations

A least-squares refinement method for isomorphous replacement

1968 • 144 citations

Primary Structure of the Bovine beta-Crystallin Bp Chain. Internal Duplication and Homology with gamma-Crystallin

1981 • 129 citations

Heat Stability of a Tetrameric Enzyme, D-Glyceraldehyde-3-PhosphateDehydrogenase

1980 • 119 citations

The amino acid sequence of γ-crystallin (fraction II) from calf lens

1972 • 119 citations

A note on the heavy-atom method

1960 • 116 citations

Eye‐lens proteins: The three‐dimensional structure of β‐crystallin predicted from monomeric γ‐crystallin

1981 • 112 citations

Computer manipulation of (macro)molecules with the method of local change

1974 • 107 citations

Protein synthesis in the core of calf lens

1968 • 103 citations

Biochemistry of bovine lens proteins II. The γ-crystallins of adult bovine, calf and embryonic lenses

1965 • 92 citations

Purification and composition studies of βs-crystallin

1966 • 89 citations

The behaviour of reduced proteins from normal and cataractous lenses in highly dissociating media: Cross-linked protein in cataractous lenses

1972 • 84 citations

PREDICTOR FOR SULFUR‐AROMATIC INTERACTIONS IN GLOBULAR PROTEINS

1980 • 68 citations

Some properties of the low molecular weight α-crystallin from normal human lens: Comparison with bovine lens

1976 • 66 citations

Detection of Bityrosine in Cataractous Human Lens Protein

1978 • 62 citations

Human β-crystallin

1980 • 60 citations

Gamma-crystallin, a major cytoplasmic polypeptide disulfide linked to membrane proteins in human cataract

1981 • 60 citations

Structural studies on calf lens γ-crystallin fraction IV: A comparison of the cysteine-containing tryptic peptides with the corresponding amino acid sequence of γ-crystallin fraction II

1978 • 59 citations

Developmental changes in the low molecular weight proteins of the bovine lens

1973 • 56 citations

Generation of molecular surfaces for graphic display

1983 • 52 citations

Evolution and diversity of the crystallins. Nucleotide sequence of a beta-crystallin mRNA from the mouse lens.

1982 • 52 citations

A theoretical comparison of the β,γ' and 2Fo–Fc syntheses

1979 • 41 citations

Bias, feedback and reliability in isomorphous phase analysis

1967 • 35 citations

The nucleotide sequence of a cloned cDNA corresponding to one of the γ‐crystallins from the eye lens of the frog Rana temporaria

1982 • 30 citations

Restrain: A restrained least squares refinement program for use in protein crystallography

1982 • 26 citations

An improved method for intensity data collection with a computer-controlled diffractometer

1975 • 24 citations

Polypeptide chain pathway in γ‐crystallin IIIb from calf lens at 3 Å resolution

1981 • 23 citations

Preliminary X-ray crystallographic study of the principal subunit of the lens structural protein, bovine β-crystallin

1982 • 22 citations

INTERACTION BETWEEN TYROSINE AND DIVALENT SULFUR IN FLUORESCENCE QUENCHING AND IN THE PHOTOCHEMISTRY OF RIBONUCLEASE

1970 • 22 citations

Fluorescence lifetimes of chromophores in intact human lenses and lens proteins

1981 • 16 citations

Crystallographic study of γ-crystallins from calf lens

1977 • 16 citations

On the Fourier refinement of protein structures

1980 • 14 citations

Preliminary X-ray crystallographic study of the bovine lens protein, γ-crystallin fraction II

1977 • 14 citations

FITZ-interactive graphics tool for investigating molecular symmetry and homology

1983 • 14 citations

The low-resolution structure analysis of the lens protein γ-crystallin

1978 • 14 citations

[Determination of the structure of the gamma-crystallin II from a calf lens with a resolution of 5 A].

1980 • 2 citations