Mechanisms of Potentiation by Calcium-Calmodulin Kinase II of Postsynaptic Sensitivity in Rat Hippocampal CA1 Neurons

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

The organization of behavior

1988 • 8,668 citations

Ionic channels of excitable membranes

1985 • 7,199 citations

Long‐lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path

1973 • 7,118 citations

Deficient Hippocampal Long-Term Potentiation in α-Calcium-Calmodulin Kinase II Mutant Mice

1992 • 1,458 citations

Activation of postsynaptically silent synapses during pairing-induced LTP in CA1 region of hippocampal slice

1995 • 1,342 citations

Inhibition of Postsynaptic PKC or CaMKII Blocks Induction But Not Expression of LTP

1989 • 1,335 citations

Evidence for silent synapses: Implications for the expression of LTP

1995 • 1,212 citations

The Biochemistry of Memory: A New and Specific Hypothesis

1984 • 1,048 citations

An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation

1989 • 1,015 citations

Contrasting properties of two forms of long-term potentiation in the hippocampus

1995 • 839 citations

Presynaptic enhancement shown by whole-cell recordings of long-term potentiation in hippocampal slices

1990 • 803 citations

The variance of sodium current fluctuations at the node of Ranvier

1980 • 772 citations

NEURONAL Ca²⁺/CALMODULIN-DEPENDENT PROTEIN KINASES

1992 • 713 citations

The probability of transmitter release at a mammalian central synapse

1993 • 632 citations

Biochemical and immunochemical evidence that the "major postsynaptic density protein" is a subunit of a calmodulin-dependent protein kinase.

1983 • 617 citations

Statistical factors involved in neuromuscular facilitation and depression

1954 • 582 citations

Selective modulation of desensitization at AMPA versus kainate receptors by cyclothiazide and concanavalin A

1993 • 581 citations

Maturation of a Central Glutamatergic Synapse

1996 • 551 citations

The Principles of the Stochastic Interpretation of Ion-Channel Mechanisms

1995 • 549 citations

The current excitement in long term potentiation

1988 • 538 citations

Inactivation of NMDA Receptors by Direct Interaction of Calmodulin with the NR1 Subunit

1996 • 532 citations

Contributions of Quisqualate and NMDA Receptors to the Induction and Expression of LTP

1988 • 512 citations

The CaM kinase II hypothesis for the storage of synaptic memory

1994 • 510 citations

A persistent postsynaptic modification mediates long-term potentiation in the hippocampus

1988 • 496 citations

Regulation of NMDA channel function by endogenous Ca2+-dependent phosphatase

1994 • 483 citations

Calcium/calmodulin-dependent kinase II and long-term potentiation enhance synaptic transmission by the same mechanism.

1995 • 451 citations

Phosphorylation and regulation of glutamate receptors by calcium/calmodulin-dependent protein kinase II

1993 • 437 citations

Mammalian Facilitative Glucose Transporter Family: Structure and Molecular Regulation

1992 • 419 citations

Long-term potentiation is associated with an increased activity of Ca2+/calmodulin-dependent protein kinase II.

1993 • 402 citations

Evidence that the major postsynaptic density protein is a component of a Ca2+/calmodulin-dependent protein kinase.

1984 • 389 citations

Regulation of Hippocampal Transmitter Release During Development and Long-Term Potentiation

1995 • 379 citations

Long-term potentiation of NMDA receptor-mediated synaptic transmission in the hippocampus

1991 • 370 citations

Hippocampal neurons exhibit cyclothiazide-sensitive rapidly desensitizing responses to kainate

1993 • 369 citations

Changes in reliability of synaptic function as a mechanism for plasticity

1994 • 367 citations

Potentiated Transmission and Prevention of Further LTP by Increased CaMKII activity in Postsynaptic Hippocampal Slice Neurons

1994 • 330 citations

Functional Modulation of Brain Sodium Channels by Protein Kinase C Phosphorylation

1991 • 325 citations

Regulation by synapsin I and Ca(2+)‐calmodulin‐dependent protein kinase II of the transmitter release in squid giant synapse.

1991 • 318 citations

LTP of AMPA and NMDA Receptor–Mediated Signals: Evidence for Presynaptic Expression and Extrasynaptic Glutamate Spill-Over

1996 • 291 citations

Regulated Subcellular Distribution of the NR1 Subunit of the NMDA Receptor

1995 • 290 citations

Amplitude fluctuations of

1994 • 288 citations

Long-term potentiation is associated with increases in quantal content and quantal amplitude

1992 • 288 citations

Presynaptic release probability influences the locus of long-term potentiation

1992 • 278 citations

Glutamate receptor channels in isolated patches from CA1 and CA3 pyramidal cells of rat hippocampal slices.

1992 • 272 citations

Convergent regulation of sodium channels by protein kinase C and cAMP-dependent protein kinase

1993 • 270 citations

Kinetic analysis of interactions between kainate and AMPA: Evidence for activation of a single receptor in mouse hippocampal neurons

1991 • 263 citations

Phosphorylation of amino acid neurotransmitter receptors in synaptic plasticity

1993 • 260 citations

Modulation of the Time Course of Fast EPSCs and Glutamate Channel Kinetics by Aniracetam

1991 • 242 citations

Transmission between pairs of hippocampal slice neurons: quantal levels, oscillations, and LTP

1991 • 241 citations

Phosphorylation of ligand‐gated ion channels: a possible mode of synaptic plasticity

1992 • 231 citations

Increased Phosphorylation of Ca2+/Calmodulin-dependent Protein Kinase II and Its Endogenous Substrates in the Induction of Long Term Potentiation

1995 • 228 citations

Direct measurement of quantal changes underlying long-term potentiation in CA1 hippocampus

1992 • 218 citations

Long-term potentiation differentially affects two components of synaptic responses in hippocampus.

1988 • 207 citations

Phosphorylation of AMPA-type glutamate receptors by calcium/calmodulin- dependent protein kinase II and protein kinase C in cultured hippocampal neurons

1994 • 188 citations

Postsynaptic injection of Ca2+/CaM induces synaptic potentiation requiring CaMKII and PKC activity

1995 • 178 citations

Evidence for all‐or‐none regulation of neurotransmitter release: implications for long‐term potentiation.

1993 • 157 citations

Mechanisms of Activation of Glutamate Receptors and the Time Course of Excitatory Synaptic Currents

1995 • 157 citations

Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS

1994 • 154 citations

Activity-dependent plasticity in the visual systems of frogs and fish

1991 • 153 citations

Insulin-stimulated GLUT4 Translocation Is Mediated by a Divergent Intracellular Signaling Pathway

1995 • 146 citations

Postsynaptic factors in the expression of long-term potentiation (LTP): increased glutamate receptor binding following LTP induction in vivo.

1993 • 133 citations

Isolated NMDA receptor-mediated synaptic responses express both LTP and LTD

1992 • 133 citations

Calcitonin gene-related peptide potentiates synaptic responses at developing neuromuscular junction

1993 • 114 citations

Long-term potentiation at single fiber inputs to hippocampal CA1 pyramidal cells.

1996 • 109 citations

Tetanically induced LTP involves a similar increase in the AMPA and NMDA receptor components of the excitatory postsynaptic current: investigations of the involvement of mGlu receptors

1995 • 108 citations

The Relative Contribution of NMDA Receptor Channels in the Expression of Long-term Potentiation in the Hippocampal CA1 Region

1992 • 107 citations

Measuring the impact of probabilistic transmission on neuronal output

1993 • 100 citations

Synaptic potentiation of dual‐component excitatory postsynaptic currents in the rat hippocampus.

1995 • 94 citations

Acetylcholine receptor assembly is stimulated by phosphorylation of its γ subunit

1991 • 75 citations

Evidence for more than one type of non‐NMDA receptor in outside‐out patches from cerebellar granule cells of the rat.

1993 • 69 citations

Channel gating kinetics and synaptic efficacy: a hypothesis for expression of long-term potentiation.

1993 • 66 citations

Changes in quantal parameters of EPSCs in rat CA1 neurones in vitro after the induction of long‐term potentiation.

1996 • 65 citations

LTP: Desperately Seeking Resolution

1994 • 55 citations

Alpha subunit of calcium/calmodulin-dependent protein kinase enhances excitatory amino acid and synaptic responses of rat spinal dorsal horn neurons

1994 • 55 citations

Expression of LTP by AMPA and/or NMDA receptors is determined by the extent of NMDA receptors activation during the tetanus

1995 • 50 citations

Enhancement of AMPA‐mediated Synaptic Transmission by the Protein Phosphatase Inhibitor Calyculin A in Rat Hippocampal Slices

1993 • 48 citations

Calcium- and calmodulin-dependent phosphorylation of AMPA type glutamate receptor subunits by endogenous protein kinases in the post-synaptic density

1997 • 38 citations

Tyrosine phosphorylation and synapse formation at the neuromuscular junction

1995 • 10 citations