Correlation of high lactate levels in head and neck tumors with incidence of metastasis.

Tumor Angiogenesis: A New Significant and Independent Prognostic Indicator in Early-Stage Breast Carcinoma

1992 • 1,799 citations

Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma.

1993 • 1,646 citations

Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma.

1996 • 1,183 citations

Transcriptional Regulation of the Rat Vascular Endothelial Growth Factor Gene by Hypoxia

1995 • 1,087 citations

Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy

1988 • 811 citations

Intratumoral pO2 predicts survival in advanced cancer of the uterine cervix

1993 • 811 citations

Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells.

1988 • 380 citations

Blood flow, metabolism, cellular microenvironment, and growth rate of human tumor xenografts.

1989 • 266 citations

Tumor angiogenesis: review of current applications in tumor prognostication.

1993 • 243 citations

Correlation of high lactate levels in human cervical cancer with incidence of metastasis.

1995 • 216 citations

Geographical mapping of metabolites in biological tissue with quantitative bioluminescence and single photon imaging

1993 • 92 citations

Clinical significance of E-cadherin as a prognostic marker in thyroid carcinomas.

1995 • 84 citations

Metabolic Imaging in Microregions of Tumors and Normal Tissues With Bioluminescence and Photon Counting

1988 • 83 citations

ATP concentrations in multicellular tumor spheroids assessed by single photon imaging and quantitative bioluminescence.

1990 • 52 citations

Assessment of tumor energy and oxygenation status by bioluminescence, nuclear magnetic resonance spectroscopy, and cryospectrophotometry.

1990 • 42 citations

Biological response of multicellular emt6 spheroids to exogenous lactate

1991 • 41 citations

Changes in tumour morphology with alterations in oxygen availability: further evidence for oxygen as a limiting substrate

1991 • 25 citations

Pixel-to-pixel correlation between images of absolute ATP concentrations and blood flow in tumours

1992 • 24 citations

Simultaneous High-Resolution Measurement of Adenosine Triphosphate Levels and Blood Flow in the Hamster Amelanotic Melanoma A-Mel-3

1992 • 19 citations

Growth rates or radiobiological hypoxia are not correlated with local metabolite content in human melanoma xenografts with similar vascular network

1995 • 10 citations