Sequence and expression of a type II keratin, K5, in human epidermal cells.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells

1982 • 5,272 citations

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

1975 • 3,483 citations

Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

1979 • 2,930 citations

Detection of mRNAs in sea urchin embryos by in situ hybridization using asymmetric RNA probes

1984 • 1,638 citations

Growth of cultured human epidermal cells into multiple epithelia suitable for grafting.

1979 • 1,248 citations

Changes in keratin gene expression during terminal differentiation of the keratinocyte

1980 • 1,059 citations

The sequence 5′-AAUAAA-3′ forms part of the recognition site for polyadenylation of late SV40 mRNAs

1981 • 819 citations

Spliced early mRNAs of simian virus 40

1978 • 817 citations

Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies

1982 • 777 citations

Rates of formation and thermal stabilities of RNA:DNA and DNA:DNA duplexes at high concentrations of formamide

1977 • 713 citations

Tropomyosin coiled-coil interactions: Evidence for an unstaggered structure

1975 • 670 citations

The mesothelial keratins: A new family of cytoskeletal proteins identified in cultured mesothelial cells and nonkeratinizing epithelia

1982 • 523 citations

Purification and mapping of specific mRNAs by hybridization-selection and cell-free translation.

1979 • 501 citations

Classification of epidermal keratins according to their immunoreactivity, isoelectric point, and mode of expression.

1984 • 440 citations

Complex Cytokeratin Polypeptide Patterns Observed in Certain Human Carcinomas

1982 • 377 citations

The 50- and 58-kdalton keratin classes as molecular markers for stratified squamous epithelia: cell culture studies.

1983 • 355 citations

Prediction of beta-turns

1979 • 352 citations

Retinoids as important regulators of terminal differentiation: examining keratin expression in individual epidermal cells at various stages of keratinization.

1987 • 343 citations

Complete amino acid sequence of a mouse epidermal keratin subunit and implications for the structure of intermediate filaments

1983 • 336 citations

The cDNA sequence of a type II cytoskeletal keratin reveals constant and variable structural domains among keratins

1983 • 326 citations

Two distinct classes of keratin genes and their evolutionary significance

1981 • 309 citations

The cDNA sequence of a human epidermal keratin: Divergence of sequence but conservation of structure among intermediate filament proteins

1982 • 298 citations

Expression of epidermal keratins and filaggrin during human fetal skin development.

1985 • 284 citations

The expression of keratin genes in epidermis and cultured epidermal cells

1978 • 264 citations

Changes in the Pattern of Cytokeratin Polypeptides in Epidermis and Hair Follicles During Skin Development in Human Fetuses

1982 • 230 citations

Structure of intermediate filaments

1983 • 195 citations

A subfamily of relatively large and basic cytokeratin polypeptides as defined by peptide mapping is represented by one or several polypeptides in epithelial cells.

1982 • 186 citations

Multiple keratins of cultured human epidermal cells are translated from different mRNA molecules

1979 • 173 citations

Remarkable conservation of structure among intermediate filament genes

1984 • 169 citations

Evidence for posttranscriptional regulation of the keratins expressed during hyperproliferation and malignant transformation in human epidermis.

1986 • 164 citations

Structure of a gene for the human epidermal 67-kDa keratin.

1985 • 160 citations

Type I and type II keratins have evolved from lower eukaryotes to form the epidermal intermediate filaments in mammalian skin.

1983 • 146 citations

Complete sequence of a gene encoding a human type I keratin: sequences homologous to enhancer elements in the regulatory region of the gene.

1985 • 142 citations

The sequence of a type II keratin gene expressed in human skin: conservation of structure among all intermediate filament genes.

1985 • 128 citations

Tissue specificity of epithelial keratins: differential expression of mRNAs from two multigene families.

1983 • 121 citations

EGF homologous sequences encoded in the genome of Drosophila melanogaster, and their relation to neurogenic genes.

1987 • 116 citations

Experimental production of antibodies against stratum corneum keratin polypeptides

1980 • 115 citations

The complete cDNA and deduced amino acid sequence of a type II mouse epidermal keratin of 60,000 Da: analysis of sequence differences between type I and type II keratins.

1984 • 110 citations

Identification of two types of keratin polypeptides within the acidic cytokeratin subfamily I

1984 • 95 citations

Coiled coil formation and sequence regularities in the helical regions of α-keratin

1978 • 79 citations

Three Tightly Linked Genes Encoding Human Type I Keratins: Conservation of Sequence in the 5′-Untranslated Leader and 5′-Upstream Regions of Coexpressed Keratin Genes

1986 • 75 citations

Amino acid sequence diversity between bovine epidermal cytokeratin polypeptides of the basic (type II) subfamily as determined from cDNA clones

1984 • 64 citations

Nonepidermal members of the keratin multigene family: cDNA sequences and in situ localization of the mRNAs

1986 • 64 citations

Cytokeratin expression in simple epithelia

1986 • 60 citations

Three tightly linked genes encoding human type I keratins: conservation of sequence in the 5'-untranslated leader and 5'-upstream regions of coexpressed keratin genes.

1986 • 53 citations

Sequence and expression of a human type II mesothelial keratin.

1985 • 49 citations

The Structure of Intermediate Filaments

1986 • 42 citations

Expression of unusually large keratins during terminal differentiation: balance of type I and type II keratins is not disrupted.

1984 • 40 citations

Tissue Specificity of Epithelial Keratins: Differential Expression of mRNAs from Two Multigene Families

1983 • 40 citations

The Transformed Phenotype

2004 • 18 citations

Amino acid sequences of α-helical segments from S-carboxymethylkerateine-A. Tryptic and chymotryptic peptides from a type-II segment

1978 • 7 citations