Sialic acid prevents loss of large von Willebrand factor multimers by protecting against amino-terminal proteolytic cleavage

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Colorimetric Method for Determination of Sugars and Related Substances

1956 • 48,885 citations

The Thiobarbituric Acid Assay of Sialic Acids

1959 • 6,482 citations

Determination of protein: A modification of the lowry method that gives a linear photometric response

1972 • 5,490 citations

Plasminogen: Purification from Human Plasma by Affinity Chromatography

1970 • 2,160 citations

Improved technique utilizing nonfat dry milk for analysis of proteins and nucleic acids transferred to nitrocellulose

1984 • 1,697 citations

endo-beta-N-acetylglucosaminidase F: endoglycosidase from Flavobacterium meningosepticum that cleaves both high-mannose and complex glycoproteins.

1982 • 689 citations

The complex multimeric composition of factor VIII/von Willebrand factor

1981 • 572 citations

Amino acid sequence of human von Willebrand factor

1986 • 486 citations

Evidence for the participation of saccharide-lipids in the synthesis of the oligosaccharide chain of ovalbumin.

1977 • 375 citations

Subunit composition of plasma von Willebrand factor. Cleavage is present in normal individuals, increased in IIA and IIB von Willebrand disease, but minimal in variants with aberrant structure of individual oligomers (types IIC, IID, and IIE).

1986 • 217 citations

Heterogeneity of type I von Willebrand disease: evidence for a subgroup with an abnormal von Willebrand factor

1985 • 187 citations

Relationship of sialic acid to function and in vivo survival of human factor VIII/von Willebrand factor protein.

1977 • 184 citations

Methods for the Production of Clinically Effective Intermediate and High‐Purity Factor‐VIII Concentrates

1971 • 181 citations

Initial glycosylation and acidic pH in the Golgi apparatus are required for multimerization of von Willebrand factor.

1986 • 164 citations

Enzymic methods for the micro assay of D-mannose, D-glucose, D-galactose, and L-fucose from acid hydrolyzates of glycoproteins

1969 • 152 citations

Human von Willebrand factor: a multivalent protein composed of identical subunits

1986 • 120 citations

Carbohydrates selectively protect a specific domain of fibronectin against proteases.

1982 • 105 citations

Topology and order of formation of interchain disulfide bonds in von Willebrand factor

1987 • 95 citations

Substructure of human von Willebrand factor. Proteolysis by V8 and characterization of two functional domains.

1986 • 94 citations

Studies of the human factor VIII/von Willebrand factor protein. III. Qualitative defects in von Willebrand's disease.

1975 • 93 citations

Studies on human antihemophilic factor. Evidence for a covalently linked subunit structure.

1976 • 86 citations

Epitope mapping of the von Willebrand factor subunit distinguishes fragments present in normal and type IIA von Willebrand disease from those generated by plasmin.

1987 • 83 citations

Carbohydrate moiety of von Willebrand factor is not necessary for maintaining multimeric structure and ristocetin cofactor activity but protects from proteolytic degradation.

1984 • 82 citations

Carbohydrate on human factor VIII/von Willebrand factor. Impairment of function by removal of specific galactose residues.

1978 • 69 citations

Factor VIII/von Willebrand factor protein. Galactose a cryptic determinant of von Willebrand factor activity.

1978 • 56 citations

Structure determination of the major asparagine‐linked sugar chain of human factor VII—von Willebrand factor

1983 • 38 citations

Preliminary results on the carbohydrate moiety of factor VIII/Von Willebrand factor (FVIII/vWf)

1982 • 31 citations

Effect of Carbohydrate Modifications of Factor VIII/ von Willebrand Factor on Binding to Platelets

1985 • 16 citations