Epitope mapping of the von Willebrand factor subunit distinguishes fragments present in normal and type IIA von Willebrand disease from those generated by plasmin.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

A dot-immunobinding assay for monoclonal and other antibodies

1982 • 2,219 citations

Plasminogen: Purification from Human Plasma by Affinity Chromatography

1970 • 2,160 citations

Improved technique utilizing nonfat dry milk for analysis of proteins and nucleic acids transferred to nitrocellulose

1984 • 1,697 citations

Proteinases in mammalian cells and tissues

1978 • 981 citations

Amino acid sequence of human von Willebrand factor

1986 • 486 citations

Platelets have more than one binding site for von Willebrand factor.

1983 • 459 citations

Two-dimensional gel analysis of soluble proteins. Charaterization of guinea pig exocrine pancreatic proteins.

1975 • 394 citations

von Willebrand factor. A reduced and alkylated 52/48-kDa fragment beginning at amino acid residue 449 contains the domain interacting with platelet glycoprotein Ib.

1986 • 270 citations

Subunit composition of plasma von Willebrand factor. Cleavage is present in normal individuals, increased in IIA and IIB von Willebrand disease, but minimal in variants with aberrant structure of individual oligomers (types IIC, IID, and IIE).

1986 • 217 citations

Methods for the Production of Clinically Effective Intermediate and High‐Purity Factor‐VIII Concentrates

1971 • 181 citations

Characterization of the human factor VIII procoagulant protein with a heterologous precipitating antibody.

1982 • 169 citations

Studies on human antihemophilic factor. Evidence for a covalently linked subunit structure.

1976 • 86 citations

Carbohydrate moiety of von Willebrand factor is not necessary for maintaining multimeric structure and ristocetin cofactor activity but protects from proteolytic degradation.

1984 • 82 citations

Effects of plasmin on von Willebrand factor multimers. Degradation in vitro and stimulation of release in vivo.

1985 • 81 citations

Cleavage of human von Willebrand factor by platelet calcium-activated protease

1985 • 80 citations

In vitro correction of the abnormal multimeric structure of von Willebrand factor in type IIa von Willebrand's disease.

1985 • 79 citations

The heterogeneity of type IIA von Willebrand's disease: studies with protease inhibitors

1986 • 59 citations

Proteolytic cleavage of human von Willebrand factor induced by enzyme(s) released from polymorphonuclear cells

1986 • 44 citations

Cleavage of human von Willebrand factor by platelet calcium-activated protease

1985 • 7 citations

Proteolytic cleavage of human von Willebrand factor induced by enzyme(s) released from polymorphonuclear cells

1986 • 5 citations