The Second Generation of Cholinesterase Inhibitors: Pharmacological Aspects

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1991 • 4,533 citations

Psychopharmacology: The third generation of progress

1988 • 3,403 citations

Psychopharmacology: The Third Generation of Progress.

1988 • 1,973 citations

Clinical, pathological, and neurochemical changes in dementia: A subgroup with preserved mental status and numerous neocortical plaques

1988 • 1,186 citations

The Genetic Defect Causing Familial Alzheimer's Disease Maps on Chromosome 21

1987 • 1,149 citations

Some morphometric aspects of the brain in senile dementia of the alzheimer type

1981 • 803 citations

Progress in Brain Research, vol 16.

1966 • 496 citations

Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder

1990 • 396 citations

Advances in Alzheimer's disease

1991 • 358 citations

Alzheimer's disease : basic mechanisms, diagnosis and therapeutic strategies

1991 • 327 citations

PREDISPOSING LOCUS FOR ALZHEIMER'S DISEASE ON CHROMOSOME 21

1989 • 271 citations

Heterogeneity of blood‐brain barrier changes in multiple sclerosis

1990 • 201 citations

Mechanisms of cholinesterase inhibition in senile dementia of the alzheimer type: Clinical, pharmacological, and therapeutic aspects

1988 • 196 citations

Cholinergic Basis for Alzheimer Therapy

1991 • 177 citations

Anatomy of cholinesterase inhibition in Alzheimer's disease: Effect of physostigmine and tetrahydroaminoacridine on plaques and tangles

1987 • 171 citations

Effect of huperzine A, a new cholinesterase inhibitor, on the central cholinergic system of the rat

1989 • 139 citations

Genetic linkage map of human chromosome 21

1988 • 125 citations

Physostigmine, tacrine and metrifonate: The effect of multiple doses on acetylcholine metabolism in rat brain

1989 • 103 citations

Chapter 34 The cholinergic system in Alzheimer disease

1990 • 98 citations

Effects of metrifonate, a long‐acting cholinesterease inhibitor, in alzheimer disease: Report of an open trial

1990 • 91 citations

Comparative inhibitory effects of various physostigmine analogs against acetyl- and butyrylcholinesterases.

1989 • 90 citations

In vitro effects of various cholinesterase inhibitors on acetyl- and butyrylcholinesterase of healthy volunteers

1991 • 86 citations

The effect of heptyl-physostigmine, a new cholinesterase inhibitor, on the central cholinergic system of the rat

1989 • 85 citations

A comparison of the effects of two inhibitors on brain cholinesterase

1987 • 75 citations

Relation of brain regional physostigmine concentration to cholinesterase activity and acetylcholine and choline levels in rat

1986 • 62 citations

Stereoselectivity of cholinesterase inhibition by galanthamine and tolerance in humans

1990 • 61 citations

Benzodiazepines, putative anxiolytics and animal models of anxiety

1991 • 47 citations

Present state and future development of the therapy of Alzheimer disease

1990 • 44 citations

Pharmacokinetics and pharmacodynamics of acetylcholinesterase inhibition: Can acetylcholine levels in the brain be improved in alzheimer's disease?

1988 • 24 citations

Interactions of 3,4-diaminopyridine and choline in stimulating acetylcholine release and protecting membrane phospholipids

1991 • 19 citations

Current Research in Alzheimer Therapy

1990 • 17 citations

Group Report 3: Early Clinical Testing of Cognition Enhancers: Prediction of Efficacy

1990 • 14 citations

Inhibition of acetylcholinestense and butyrylcholinesterase after oral administration of heptastigmine in healthy volunteers

1990 • 5 citations

Presynaptic Markers of Cholinergic Function in Cortex Following Ibotenic Acid Lesion of the Basal Forebrain

1989 • 4 citations

WHAT, WHERE, AND WHY ARE PLAQUES

1988 • 4 citations

Immunocytochemistry of Muscarinic and Nicotinic Receptors in Human Brain

1991 • 2 citations

Cortical Cholinesterases in Alzheimer’s Disease: Anatomical and Enzymatic Shifts from the Normal Pattern

1991 • 2 citations

Psychopharmacologist

2013 • 2 citations

Deleted Work

1955 • 0 citations