Response : Carcinogenicity Tests

Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test

1975 • 7,413 citations

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

1975 • 3,362 citations

Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection

1973 • 2,275 citations

An Improved Bacterial Test System for the Detection and Classification of Mutagens and Carcinogens

1973 • 1,519 citations

Mutation selection and the natural history of cancer

2006 • 1,185 citations

Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids.

1975 • 1,030 citations

Evidence for a Monoclonal Origin of Human Atherosclerotic Plaques

1973 • 900 citations

Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division.

1973 • 843 citations

Chemical Carcinogenesis

1975 • 741 citations

Identification of mutagenic metabolites of benzo(a)pyrene in mammalian cells.

1976 • 483 citations

Hair dyes are mutagenic: identification of a variety of mutagenic ingredients.

1975 • 474 citations

XERODERMA PIGMENTOSUM: BIOCHEMICAL AND GENETIC CHARACTERISTICS

1975 • 406 citations

<italic>In Vitro</italic> Transformation of Normal Cells to Tumor Cells by Carcinogenic Hydrocarbons<xref ref-type="fn" rid="FN2">2</xref>

1965 • 400 citations

Detection of Mutagenic Activity in Cigarette Smoke Condensates

1974 • 284 citations

Mutation and Human Cancer

1973 • 210 citations

The Cancer Problem

1975 • 209 citations

Effect of dimethylnitrosamine on persistence of methylated guanines in rat liver and kidney DNA

1975 • 193 citations

In Vitro Transformation of Rodent Cells by K-Region Derivatives of Polycyclic Hydrocarbons

1971 • 190 citations

Mutagenicity of chloroacetaldehyde, a possible metabolic product of 1,2-dichloroethane (ethylene dichloride), chloroethanol (ethylene chlorohydrin), vinyl chloride, and cyclophosphamide.

1975 • 190 citations

<italic>Brief Communication:</italic> Carcinogenicity of N-Methyl-N-nitrosourea: Possible Role of Excision Repair of O<sup>6</sup>-Methylguanine From DNA

1974 • 182 citations

Induction of chromosome changes in Chinese hamster cells by exposure to asbestos fibres

1975 • 182 citations

Intrinsic Mutagenesis: A Genetic Approach to Ageing.

1975 • 177 citations

A Simple Method for the Detection of Mutagens in Urine: Studies with the Carcinogen 2-Acetylaminofluorene

1974 • 169 citations

Mutagenicity of non-K-region diols and diol-epoxides of benz(a)anthracene and benzo(a)pyrene in S. typhimurium TA 100

1975 • 168 citations

Identification of the Chromosomes that Control Malignancy

1973 • 106 citations

Environmental determinants of human cancer.

1974 • 95 citations

Carcinogenicity and mutagenicity tests of some hair colourants and constituents

1975 • 88 citations

Variants of a mouse myeloma cell line that synthesize immunoglobulin heavy chains having an altered serotype.

1975 • 84 citations

Binding of K-region epoxides and other derivatives of benz[a]anthracene and dibenz[a,h]anthracene to DNA, RNA and proteins of transformable cells

1972 • 76 citations

Variants of Mouse Myeloma Cells That Produce Short Immunoglobulin Heavy Chains

1974 • 76 citations

Mutagenic and cytotoxic activity of benzol[a]pyrene 4,5-, 7,8-, and 9,10-oxides and the six corresponding phenols.

1975 • 75 citations

Correlation Between Balance of Specific Chromosomes and Expression of Malignancy in Hamster Cells 2

1975 • 74 citations

Malignant transformation of mouse cells by cigarette smoke condensate.

1975 • 36 citations

In vitro malignant transformation of cells by chemical carcinogens

1974 • 32 citations

Reversible appearance of a specific chromosome which suppresses malignancy

1974 • 28 citations

Early Changes in Chromosomal Number and Structure After Treatment of Fetal Hamster Cultures With Transforming Doses of Polycyclic Hydrocarbons

1972 • 23 citations

<italic>Brief Communication:</italic> Correlation Between the Carcinogenicities of Nitrofuran Derivatives and Their Destructive Actions on Sebaceous Glands of Mouse Skin<xref ref-type="fn" rid="fn2">2</xref>

1975 • 4 citations