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Mutagenicity of chloroacetaldehyde, a possible metabolic product of 1,2-dichloroethane (ethylene dichloride), chloroethanol (ethylene chlorohydrin), vinyl chloride, and cyclophosphamide.

Data up to Jan 2025

Published1975
Citations190
References35

Total Citations Per Year

Abstract

References (35)

Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection

1973 • 2,275 citations

An Improved Bacterial Test System for the Detection and Classification of Mutagens and Carcinogens

1973 • 1,519 citations

Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids.

1975 • 1,030 citations

Angiosarcoma of liver in the manufacture of polyvinyl chloride.

1974 • 538 citations

Hair dyes are mutagenic: identification of a variety of mutagenic ingredients.

1975 • 474 citations

Carcinogens as Frameshift Mutagens: Metabolites and Derivatives of 2-Acetylaminofluorene and Other Aromatic Amine Carcinogens

1972 • 361 citations

Detection of Mutagenic Activity in Cigarette Smoke Condensates

1974 • 284 citations

Fluorescent adenosine and cytidine derivatives

1972 • 283 citations

Oncogenic response of rat skin, lungs, and bones to vinyl chloride.

1971 • 260 citations

Epoxides of Carcinogenic Polycyclic Hydrocarbons Are Frameshift Mutagens

1972 • 225 citations

Frameshift Mutagenesis in Salmonella

1966 • 224 citations

Some Catalytic Properties of Human Liver Alcohol Dehydrogenase*

1966 • 214 citations

Human, rat and mouse liver‐mediated mutagenicity of vinyl chloride in S. typhimurium strains

1975 • 194 citations

Induction of Stomach Cancer in Rats and Mice by Halogenated Aliphatic Fumigants

1973 • 193 citations

Chlorinated hydrocarbons and the environment

1975 • 186 citations

Mutagenicity of vinyl chloride, chloroethyleneoxide, chloroacetaldehyde and chloroethanol

1975 • 177 citations

A Simple Method for the Detection of Mutagens in Urine: Studies with the Carcinogen 2-Acetylaminofluorene

1974 • 169 citations

Antitumor and mutagenic properties of a variety of heterocyclic nitrogen and sulfur mustards

1972 • 133 citations

The mutagenicity and DNA-modifying effect of haloalkanes.

1974 • 130 citations

Vinyl chloride exposure and human chromosome aberrations

1975 • 110 citations

CHROMOSOME ABERRATIONS IN WORKERS EXPOSED TO VINYL CHLORIDE

1975 • 110 citations

ON THE POSSIBLE MECHANISM OF CARCINOGENIC ACTION OF VINYL CHLORIDE

1975 • 87 citations

Metabolism of 1,2‐Dichloroethane‐14C in the Mouse

1971 • 63 citations

On the mutagenic action of dichlorvos

1972 • 62 citations

Mutagenic activity of cyclophosphamide, ifosfamide, and trofosfamide in different genes of Escherichia coli and Salmonella typhimurium after biotransformation through extracts of rodent liver

1975 • 60 citations

A new method for testing genetically active metabolites Urinary assay with cyclophosphamide (endoxan, cytoxan) and Saccharomyces cerevisiae

1973 • 53 citations

Toxicity Profile of Chloroacetaldehyde

1972 • 53 citations

Cyclophosphamide: Pilot study of genetically active metabolites in the urine of a treated human patient induction of mitotic gene conversions in yeast

1973 • 48 citations

2-haloethanols: Mutagenicity and reactivity with DNA

1974 • 48 citations

The Metabolism of Biological Alkylating Agents

1974 • 45 citations

Mutagenic action of ethylene halogenhydrins

1969 • 25 citations

Physical studies of chloroacetaldehyde labelled fluorescent DNA

1973 • 24 citations

Hepatic microsomal ethanol oxidation. Mechanism and physiologic significance.

1972 • 16 citations

Ethanol and drug metabolism in mouse liver microsomes subsequent to lipid peroxidation-induced destruction of cytochrome P-450

1974 • 15 citations

Toxicological studies of compounds investigated for use as inhibitors of biological processes. II. Toxicity of ethylene chlorohydrin.

1950 • 12 citations

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Mutagenicity of chloroacetaldehyde, a possible metabolic product of 1,2-dichloroethane… (1975) – Proceedings of the National Academy of Sciences | Metascience Observatory Explorer