A Comparison of Etanercept and Methotrexate in Patients with Early Rheumatoid Arthritis

American college of rheumatology preliminary definition of improvement in rheumatoid arthritis

1995 • 2,778 citations

A Trial of Etanercept, a Recombinant Tumor Necrosis Factor Receptor:Fc Fusion Protein, in Patients with Rheumatoid Arthritis Receiving Methotrexate

1999 • 2,117 citations

Treatment of Rheumatoid Arthritis with a Recombinant Human Tumor Necrosis Factor Receptor (p75)–Fc Fusion Protein

1997 • 1,651 citations

Etanercept Therapy in Rheumatoid Arthritis

1999 • 1,407 citations

Etanercept in Children with Polyarticular Juvenile Rheumatoid Arthritis

2000 • 1,211 citations

Detection of tumor necrosis factor α but not tumor necrosis factor β in rheumatoid arthritis synovial fluid and serum

1988 • 570 citations

Methods of scoring the progression of radiologic changes in rheumatoid arthritis. Correlation of radiologic, clinical and laboratory abnormalities

1971 • 502 citations

Biannual Radiographic Assessments of Hands and Feet in a Three‐Year Prospective Followup of Patients with Early Rheumatoid Arthritis

1992 • 441 citations

How many joints in the hands and wrists should be included in a score of radiologic abnormalities used to assess rheumatoid arthritis?

1985 • 419 citations

Decrease in cellularity and expression of adhesion molecules by anti–tumor necrosis factor α monoclonal antibody treatment in patients with rheumatoid arthritis

1996 • 377 citations

The safety and efficacy of the use of methotrexate in long‐term therapy for rheumatoid arthritis

1986 • 362 citations

Radiographic outcome of recent-onset rheumatoid arthritis: A 19-year study of radiographic progression

1998 • 284 citations

Remodeling the pyramid--a concept whose time has come.

1989 • 246 citations

Deactivation of vascular endothelium by monoclonal anti–tumor necrosis factor α antibody in rheumatoid arthritis

1996 • 239 citations

Long‐term prospective trial of low‐dose methotrexate in rheumatoid arthritis

1988 • 234 citations

Long‐Term Prospective Study of Methotrexate in the Treatment of Rheumatoid Arthritis

1992 • 227 citations

Should imporvement in rheumatoid arthritis clinical trials be defined as fifty percent or seventy percent improvement in core set measures, rather than twenty percent?

1998 • 192 citations

Individual relationship between progression of radiological damage and the acute phase response in early rheumatoid arthritis. Towards development of a decision support system.

1997 • 188 citations

Adverse effects of low dose methotrexate therapy in rheumatoid arthritis.

1993 • 121 citations

Methotrexate versus azathioprine in the treatment of rheumatoid arthritis. A forty‐eight–week randomized, double‐blind trial

1991 • 115 citations

The effects of drug therapy on radiographic progression of rheumatoid arthritis. results of a 36‐week randomized trial comparing methotrexate and auranofin

1993 • 100 citations

Measurement and prediction of radiological progression in early rheumatoid arthritis.

1994 • 79 citations

Treatment of rheumatoid arthritis with methotrexate: a prospective open longterm study of 191 cases.

1991 • 76 citations

When does rheumatoid arthritis begin and why do we need to know?

2000 • 74 citations

Radiographic assessment of disease progression in rheumatoid arthritis patients enrolled in the cooperative systematic studies of the rheumatic diseases program randomized clinical trial of methotrexate, auranofin, or a combination of the two

1993 • 50 citations