Deactivation of vascular endothelium by monoclonal anti–tumor necrosis factor α antibody in rheumatoid arthritis

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

1988 • 19,632 citations

Leukocyte-endothelial adhesion molecules

1994 • 2,567 citations

ROLE OF CYTOKINES IN RHEUMATOID ARTHRITIS

1996 • 2,527 citations

Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor α (cA2) versus placebo in rheumatoid arthritis

1994 • 1,695 citations

Circulating adhesion molecules in disease

1993 • 1,425 citations

INHIBITORY EFFECT OF TNF$alpha; ANTIBODIES ON SYNOVIAL CELL INTERLEUKIN-1 PRODUCTION IN RHEUMATOID ARTHRITIS

1989 • 1,137 citations

Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor α

1993 • 1,031 citations

Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis.

1992 • 1,002 citations

Inhibition of the production and effects of interleukins‐1 and tumor necrosis factor α in rheumatoid arthritis

1995 • 917 citations

Construction and initial characterization of a mouse-human chimeric anti-TNF antibody

1993 • 714 citations

Soluble forms of E-selectin, ICAM-1 and VCAM-1 are present in the supernatants of cytokine activated cultured endothelial cells

1992 • 653 citations

Angiogenesis mediated by soluble forms of E-selectin and vascular cell adhesion molecule-1

1995 • 599 citations

E-selectin and intercellular adhesion molecule-1 are released by activated human endothelial cells in vitro.

1992 • 519 citations

Soluble Forms of Vascular Adhesion Molecules, E‐Selectin, ICAM‐1, and VCAM‐1: Pathological Significance

1992 • 406 citations

TNFα—A PIVOTAL ROLE IN RHEUMATOID ARTHRITIS?

1992 • 377 citations

Immunolocalization of endothelial and leukocyte adhesion molecules in human rheumatoid and osteoarthritic synovial tissues.

1991 • 295 citations

Expression of granulocyte‐macrophage colony‐stimulating factor in rheumatoid arthritis: Regulation by tumor necrosis factor‐α

1991 • 290 citations

Analysis of improvement in individual rheumatoid arthritis patients treated with disease‐modifying antirheumatic drugs, based on the findings in patients treated with placebo

1990 • 289 citations

Modulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. Comparison of monoclonal anti TNF-alpha antibody with the interleukin-1 receptor antagonist.

1995 • 286 citations

Treatment of refractory rheumatoid arthritis with a monoclonal antibody to intercellular adhesion molecule 1

1994 • 263 citations

Sequential observation of micrometastasis formation by bacterial lacZ gene-tagged Lewis lung carcinoma cells

1997 • 258 citations

Angiogenesis and rheumatoid arthritis: pathogenic and therapeutic implications.

1992 • 212 citations

Adhesion molecule expression in human synovial tissue

1993 • 211 citations

Monoclonal anti‐TNFα Antibody as a Probe of Pathogenesis and Therapy of Rheumatoid Disease

1995 • 182 citations

Expression and functional characterization of a soluble form of endothelial-leukocyte adhesion molecule 1.

1991 • 141 citations

Detection of increased levels of circulating intercellular adhesion molecule 1 in some patients with rheumatoid arthritis but not in patients with systemic lupus erythematosus. lack of correlation with levels of circulating vascular cell adhesion molecule 1

1993 • 139 citations

Detection of a circulating form of vascular cell adhesion molecule-1: raised levels in rheumatoid arthritis and systemic lupus erythematosus

1993 • 139 citations

Differential Distribution of Intercellular Adhesion Molecules (ICAM–1, ICAM–2, and ICAM–3) and THE MS–1 Antigen in Normal and Diseased Human Synovia

1994 • 131 citations

Synthetic fibronectin peptides suppress arthritis in rats by interrupting leukocyte adhesion and recruitment.

1994 • 116 citations

Increased levels of circulating intercellular adhesion molecule 1 in the sera of patients with rheumatoid arthritis

1993 • 96 citations

Gold treatment of rheumatoid arthritis decreases synovial expression of the endothelial leukocyte adhesion receptor ELAM-1.

1991 • 88 citations

Expression and functional characterization of a soluble form of vascular cell adhesion molecule 1

1991 • 81 citations

The effect of anti-adhesion molecule antibody on the development of collagen-induced arthritis

1992 • 74 citations

The role of tumour necrosis factor-alpha and IL-1 in polymorphonuclear leucocyte and T lymphocyte recruitment to joint inflammation in adjuvant arthritis

1994 • 71 citations

Soluble E-Selectin in Arthritis

1993 • 57 citations

Gold treatment of rheumatoid arthritis decreases synovial expression of the endothelial leukocyte adhesion receptor ELAM-1.

1991 • 43 citations

A Major Portion of Polymorphonuclear Leukocyte and T Lymphocyte Migration to Arthritic Joints in the Rat Is via LFA-1/MAC-1-Independent Mechanisms

1993 • 36 citations

Adhesion molecules in the pathogenesis of rheumatoid arthritis

1994 • 32 citations