Internalization and intracellular fate of anti-CD5 monoclonal antibody and anti-CD5 ricin A-chain immunotoxin in human leukemic T cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity

1962 • 6,970 citations

Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using protein A-Sepharose

1978 • 2,726 citations

Coated pits, coated vesicles, and receptor-mediated endocytosis

1979 • 2,073 citations

The trans Golgi Network: Sorting at the Exit Site of the Golgi Complex

1986 • 1,175 citations

ANALYTICAL STUDY OF MICROSOMES AND ISOLATED SUBCELLULAR MEMBRANES FROM RAT LIVER

1974 • 840 citations

Recycling receptors: The round-trip itinerary of migrant membrane proteins

1983 • 780 citations

Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts

1977 • 688 citations

Receptor-mediated endocytosis

1985 • 577 citations

Receptor-mediated endocytosis of transferrin in K562 cells.

1983 • 576 citations

Studies on glucosaminidase. 4. The fluorimetric assay of N-acetyl-β-glucosaminidase

1961 • 458 citations

A Monoclonal Antibody with Selective Reactivity with Functionally Mature Human Thymocytes and All Peripheral Human T Cells

1979 • 456 citations

Human T cell antigens defined by monoclonal antibodies: the 65,000-dalton antigen of T cells (T65) is also found on chronic lymphocytic leukemia cells bearing surface immunoglobulin.

1980 • 429 citations

Ribosome Inactivation by the Toxic Lectins Abrin and Ricin

1975 • 208 citations

Morphologic characterization of the pathway of transferrin endocytosis and recycling in human KB cells.

1984 • 202 citations

Kinetics of cytotoxicity induced by immunotoxins. Enhancement by lysosomotropic amines and carboxylic ionophores.

1984 • 194 citations

Cytofluorometric quantification of cell-surface antigens by indirect immunofluorescence using monoclonal antibodies

1985 • 192 citations

Immunotoxins: Hybrid Molecules Combining High Specificity and Potent Cytotoxicity

1982 • 181 citations

Internalization and rapid recycling of macrophage Fc receptors tagged with monovalent antireceptor antibody: possible role of a prelysosomal compartment.

1984 • 176 citations

Complete inhibition of transferrin recycling by monensin in K562 cells.

1984 • 120 citations

Human melanoma cells can be killed in vitro by an immunotoxin specific for melanoma‐associated antigen p97

1982 • 116 citations

Evaluation of ricin A-chain immunotoxins directed against human T cells

1986 • 85 citations

Use of multiple T cell-directed intact ricin immunotoxins for autologous bone marrow transplantation

1985 • 77 citations

Cell Biology of Intracellular Protein Trafficking

1990 • 64 citations

Endocytosis of an antibody ricin A-chain conjugate (immuno-A-toxin) adsorbed on colloidal gold. Effects of ammonium chloride and monensin.

1985 • 52 citations

Immunotoxins show rapid entry of diphtheria toxin but not ricin via the T3 antigen.

1986 • 43 citations

The role of ricin B chain in the intracellular trafficking of anti-CD5 immunotoxins.

1989 • 40 citations

Biochemical aspects of immunotoxin preparation

1985 • 37 citations

Comparison of the cytotoxic potency of T101 Fab, F(ab')2 and whole IgG immunotoxins.

1988 • 31 citations

Antigenic modulation by anti-CD5 immunotoxins.

1986 • 25 citations

Studies on components of immunotoxins: Purification of ricin and its subunits and influence of unreacted antibodies

1985 • 19 citations

Significance of the Kinetics of Immunotoxin Cytotoxicity

1984 • 18 citations

Distribution of endocytosed molecules to intracellular acidic environments correlates with immunotoxin activity

1990 • 18 citations

Human leukemia cell binding and killing by anti-CD5 radioimmunotoxins

1987 • 15 citations

Internalization of the cytotoxic molecules of T101 F(ab′)₂— (ricin‐A‐chain) immunotoxin into human T‐leukemic cells

1990 • 13 citations