Leukemia translocation gene, PLZF, is expressed with a speckled nuclear pattern in early hematopoietic progenitors

Chromosomal translocations in human cancer

1994 • 1,551 citations

Requirement of Transcription Factor PU.1 in the Development of Multiple Hematopoietic Lineages

1994 • 1,506 citations

The induction of differentiation in teratocarcinoma stem cells by retinoic acid

1978 • 1,459 citations

An early haematopoietic defect in mice lacking the transcription factor GATA-2

1994 • 1,412 citations

A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

1991 • 1,074 citations

The ikaros gene is required for the development of all lymphoid lineages

1994 • 976 citations

Hematopoietic commitment during embryonic stem cell differentiation in culture.

1993 • 919 citations

GATA-binding transcription factors in hematopoietic cells

1992 • 845 citations

Segmental patterns of neuronal development in the chick hindbrain

1989 • 840 citations

Cloning of murine α and β retinoic acid receptors and a novel receptor γ predominantly expressed in skin

1989 • 804 citations

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

1994 • 798 citations

The POZ domain: a conserved protein-protein interaction motif.

1994 • 770 citations

Acute Promyelocytic Leukemia

2015 • 764 citations

Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells

1994 • 752 citations

GATA-binding transcription factors in hematopoietic cells

1992 • 727 citations

A Novel, Erythroid Cell-Specific Murine Transcription Factor that Binds to the CACCC Element and is Related to the Krüppel Family of Nuclear Proteins†

1993 • 703 citations

Alterations of a Zinc Finger-Encoding Gene, BCL-6 , in Diffuse Large-Cell Lymphoma

1993 • 680 citations

Retinoic acid regulates aberrant nuclear localization of PML-RARα in acute promyelocytic leukemia cells

1994 • 668 citations

Fusion between a novel Krüppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia.

1993 • 658 citations

Preferential utilization of the most JH-proximal VH gene segments in pre-B-cell lines

1984 • 644 citations

Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF

1995 • 620 citations

Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene

1995 • 572 citations

Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines.

1983 • 559 citations

An early pre-liver intraembryonic source of CFU-S in the developing mouse

1993 • 525 citations

The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion.

1994 • 492 citations

Acute promyelocytic leukemia: from genetics to treatment

1994 • 474 citations

Visualization of replication factories attached to a nucleoskeleton

1993 • 472 citations

A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Krüppel family of nuclear proteins.

1993 • 464 citations

The t(5;17) variant of acute promyelocytic leukemia expresses a nucleophosmin-retinoic acid receptor fusion

1996 • 463 citations

Ikaros, an Early Lymphoid-Specific Transcription Factor and a Putative Mediator for T Cell Commitment

1992 • 458 citations

LAZ3, a novel zinc–finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas

1993 • 444 citations

Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteins.

1992 • 441 citations

Para-aortic splanchnopleura from early mouse embryos contains B1a cell progenitors

1993 • 392 citations

The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineage

1993 • 384 citations

Acute promyelocytic leukemia: from genetics to treatment

1994 • 384 citations

Cytokine-dependent granulocytic differentiation. Regulation of proliferative and differentiative responses in a murine progenitor cell line.

1987 • 369 citations

Clinical and molecular characterization of a rare syndrome of acute promyelocytic leukemia associated with translocation (11;17)

1995 • 352 citations

PMLRAR homodimers: distinct DNA binding properties and heteromeric interactions with RXR.

1993 • 307 citations

A transplantable myelomonocytic leukemia in BALB-c mice: cytology, karyotype, and muramidase content.

1969 • 276 citations

Hematopoietic Commitment During Embryonic Stem Cell Differentiation in Culture

1993 • 273 citations

A novel zinc finger coiled-coil domain in a family of nuclear proteins

1992 • 260 citations

A dominant negative retinoic acid receptor blocks neutrophil differentiation at the promyelocyte stage.

1993 • 233 citations

Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia.

1993 • 228 citations

A defined subgenomic fragment of in vitro synthesized Moloney sarcoma virus DNA can induce cell transformation upon transfection

1979 • 187 citations

Concentration-dependent transcriptional activation or repression by Krüppel from a single binding site

1991 • 166 citations

Structure, chromosome location, and expression of the human gamma-actin gene: differential evolution, location, and expression of the cytoskeletal beta- and gamma-actin genes.

1988 • 160 citations

A mutated retinoic acid receptor-alpha exhibiting dominant-negative activity alters the lineage development of a multipotent hematopoietic cell line.

1992 • 160 citations

Immunodetection of multiple species of retinoic acid receptor α: Evidence for phosphorylation

1992 • 129 citations

Direct toxic effects of immunopotentiators on monocytic, myelomonocytic, and histiocytic or macrophage tumor cells in culture.

1977 • 122 citations

The Role of Hemopoietic Growth Factors in Self-Renewal and Differentiation of IL-3-Dependent Multipotential Stem Cells

1990 • 121 citations

Zinc finger proteins: what we know and what we would like to know

1991 • 121 citations

Expression of the zinc-finger gene PLZF at rhombomere boundaries in the vertebrate hindbrain.

1995 • 115 citations

Erythrocytic maturation in vitro of murine (Friend) virus-induced leukemic cells.

1966 • 115 citations

Isolation and characterisation of a bipotential haematopoietic cell line

1979 • 107 citations

Reduced and altered DNA-binding and transcriptional properties of the PLZF-retinoic acid receptor-alpha chimera generated in t(11;17)-associated acute promyelocytic leukemia.

1996 • 86 citations

Antisense oligonucleotides from the stage-specific myeloid zinc finger gene MZF-1 inhibit granulopoiesis in vitro.

1991 • 79 citations

Wholemount in situ hybridization of vertebrate embryos

1992 • 78 citations

Localisation of splicing snRNPs in mammalian cells

1993 • 67 citations

A non-classical translocation involving 17q12 (retinoic acid receptor alpha) in acute promyelocytic leukemia (APML) with atypical features.

1994 • 63 citations

Acute Promyelocytic Leukemia

1994 • 62 citations

Expression of lineage restricted transcription factors precedes lineage specific differentiation in a multipotent haemopoietic progenitor cell line.

1994 • 61 citations

Inhibitory Effects of Lectins and Lymphocyte Mitogens on Murine Lymphomas and Myelomas2

1973 • 56 citations

TRANSLOCATION OF THE RARα LOCUS TO THE PML OR PLZF GENE IN ACUTE PROMYELOCYTIC LEUKAEMIA

1994 • 39 citations

Induction of differentiation of avian erythroblastosis virus-transformed erythroblasts by the protein kinase inhibitor H7: analysis of the transcription factor EF1.

1991 • 15 citations