Expression of immune regulatory molecules in Epstein-Barr virus-associated nasopharyngeal carcinomas with prominent lymphoid stroma. Evidence for a functional interaction between epithelial tumor cells and infiltrating lymphoid cells.

Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).

1984 • 3,268 citations

CTLA-4 is a second receptor for the B cell activation antigen B7.

1991 • 1,662 citations

The B7 and CD28 receptor families

1994 • 1,342 citations

The Role of the CD28 Receptor During T Cell Responses to Antigen

1993 • 1,320 citations

Epstein–Barr Virus in Burkitt's Lymphoma and Nasopharyngeal Carcinoma: EBV DNA in Biopsies of Burkitt Tumours and Anaplastic Carcinomas of the Nasopharynx

1970 • 1,261 citations

An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells

1985 • 1,257 citations

Induction of bcl-2 expression by epstein-barr virus latent membrane protein 1 protects infected B cells from programmed cell death

1991 • 1,195 citations

The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferation

1986 • 927 citations

Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23

1990 • 585 citations

Epstein-Barr virus latent gene transcription in nasopharyngeal carcinoma cells: coexpression of EBNA1, LMP1, and LMP2 transcripts

1992 • 493 citations

Epstein--Barr Virus Gene Expression in Nasopharyngeal Carcinoma

1988 • 479 citations

Expression of Epstein‐Barr virus‐encoded proteins in nasopharyngeal carcinoma

1988 • 447 citations

Recombinant human CD40 ligand stimulates B cell proliferation and immunoglobulin E secretion.

1992 • 409 citations

Epstein-Barr virus latent infection membrane protein alters the human B-lymphocyte phenotype: deletion of the amino terminus abolishes activity

1988 • 403 citations

Epstein–Barr virus latent membrane protein inhibits human epithelial cell differentiation

1990 • 377 citations

Gastric carcinoma with lymphoid stroma.Its morphologic characteristics and prognostic correlations

1976 • 347 citations

Morphological transformation of human keratinocytes expressing the LMP gene of Epstein Barr virus

1990 • 299 citations

B lymphoblast antigen (BB-1) expressed on Epstein-Barr virus-activated B cell blasts, B lymphoblastoid cell lines, and Burkitt's lymphomas.

1982 • 297 citations

Abundant expression of EBER1 small nuclear RNA in nasopharyngeal carcinoma. A morphologically distinctive target for detection of Epstein-Barr virus in formalin-fixed paraffin-embedded carcinoma specimens.

1991 • 248 citations

Histopathology of nasopharyngeal carcinoma.Correlations with epidemiology, survival rates and other biological characteristics

1979 • 235 citations

Activated human B lymphocytes express three CTLA-4 counterreceptors that costimulate T-cell activation.

1993 • 207 citations

Bcl‐2 proto‐oncogene expression in epstein‐barr‐virus‐associated nasopharyngeal carcinoma

1993 • 198 citations

Suppression of apoptosis in normal and neoplastic human B lymphocytes by CD40 ligand is independent of Bcl‐2 induction

1993 • 180 citations

T cell costimulation by B7/BB1 induces CD8 T cell-dependent tumor rejection: an important role of B7/BB1 in the induction, recruitment, and effector function of antitumor T cells.

1994 • 174 citations

CD27: marker and mediator of T-cell activation?

1994 • 169 citations

A histological classification of carcinomas of the nasopharynx with a critical review as to the existence of lymphoepitheliomas

1962 • 149 citations

T lymphocyte T cell-B cell-activating molecule/CD40-L molecules induce normal B cells or chronic lymphocytic leukemia B cells to express CD80 (B7/BB-1) and enhance their costimulatory activity.

1994 • 149 citations

Augmentation of normal and malignant B cell proliferation by monoclonal antibody to the B cell-specific antigen BP50 (CDW40).

1987 • 141 citations

The cloning of CD70 and its identification as the ligand for CD27.

1994 • 139 citations

Expression of Epstein-Barr virus genes and of lymphocyte activation molecules in undifferentiated nasopharyngeal carcinomas.

1992 • 136 citations

Lymphocyte subsets in tumour of patients with undifferentiated nasopharyngeal carcinoma: presence of lymphocytes with the phenotype of activated T cells

1987 • 119 citations

T-BAM/CD40-L on helper T lymphocytes augments lymphokine-induced B cell Ig isotype switch recombination and rescues B cells from programmed cell death.

1994 • 117 citations

CD70 represents the human ligand for CD27

1994 • 113 citations

Discordant expression of CD28 ligands, BB-1, and B7 on keratinocytes in vitro and psoriatic cells in vivo.

1993 • 103 citations

In vivo expression of the B7 costimulatory molecule by subsets of antigen-presenting cells and the malignant cells of Hodgkin's disease

1994 • 102 citations

Expression and function of CD40 on Hodgkin and Reed-Sternberg cells and the possible relevance for Hodgkin's disease

1994 • 96 citations

The B7-2 (B70) costimulatory molecule expressed by monocytes and activated B lymphocytes is the CD86 differentiation antigen

1994 • 83 citations

Epstein-Barr virus-containing epithelial cells from nasopharyngeal carcinoma produce interleukin 1 alpha.

1987 • 70 citations

Epstein-Barr virus and CD30+ malignant lymphomas.

1993 • 69 citations

Uterine Cervical Lymphoepithelial-like Carcinoma: Absence of Epstein–Barr Virus Genomes

1993 • 67 citations

Cytotoxic potential despite impaired activation pathways in T lymphocytes infiltrating nasopharyngeal carcinoma

1991 • 54 citations

The combination of anti-B7 monoclonal antibody and cyclosporin A induces alloantigen-specific anergy during a primary mixed lymphocyte reaction.

1994 • 47 citations

The Epstein-Barr virus encoded membrane protein (LMP) induces phenotypic changes in epithelial cells

1992 • 40 citations

Activated T lymphocytes in infiltrates and draining lymph nodes of nasopharyngeal carcinoma

1980 • 34 citations

Nasopharyngeal Carcinoma and Lymphoinfiltration

1991 • 33 citations

Influence of CD28 co-stimulation on cytokine production is mainly regulated via interleukin-2.

1994 • 25 citations

Immunohistological characteristics of the infiltrating lymphoid cells and expression of HLA class I and II antigens in nasopharyngeal carcinoma

1990 • 15 citations

Heterogeneity among human nasopharyngeal carcinoma cell lines for inflammatory cytokines mRNA expression levels

1992 • 8 citations