Lys-197 and Asp-414 are critical residues for binding of ATP/Mg2+ by rat brain inositol 1,4,5-trisphosphate 3-kinase

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.

1982 • 5,284 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

Inositol phosphates and cell signalling

1989 • 4,058 citations

Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

1979 • 2,930 citations

The P-loop — a common motif in ATP- and GTP-binding proteins

1990 • 2,029 citations

The inositol tris/tetrakisphosphate pathway—demonstration of Ins(l,4,5)P3 3-kinase activity in animal tissues

1986 • 702 citations

ATP-binding site of adenylate kinase: mechanistic implications of its homology with ras-encoded p21, F1-ATPase, and other nucleotide-binding proteins.

1986 • 538 citations

5′–3′ Exonucleases in phosphorothioate-based oligonucleotide-directed mutagenesis

1988 • 336 citations

Stable DNA heteroduplex formation catalyzed by the Escherichia coli RecA protein in the absence of ATP hydrolysis.

1990 • 249 citations

Neither arginine nor histidine can carry out the function of lysine-295 in the ATP-binding site of p60src.

1986 • 156 citations

[7] λgt 11: Gene isolation with antibody probes and other applications

1987 • 155 citations

Molecular Cloning and Expression of a Complementary DNA for Inositol 1,4,5-Trisphosphate 3-Kinase

1990 • 142 citations

Cloning and expression in Escherichia coli of a rat brain cDNA encoding a Ca2+/calmodulin-sensitive inositol 1,4,5-trisphosphate 3-kinase

1990 • 88 citations

Catalytic properties of inositol trisphosphate kinase: activation by Ca ²⁺ and calmodulin

1987 • 84 citations

Calcium-calmodulin stimulates inositol 1,4,5-trisphosphate kinase activity from insulin-secreting RINm5F cells.

1987 • 83 citations

Regulation of D-myo-inositol 1,4,5-trisphosphate 3-kinase by cAMP-dependent protein kinase and protein kinase C.

1990 • 74 citations

Molecular cloning and expression of a new putative inositol 1,4,5-trisphosphate 3-kinase isoenzyme

1991 • 73 citations

Purification of bovine brain inositol 1,4,5-trisphosphate 3-kinase. Identification of the enzyme by sodium dodecyl sulphate/polyacrylamide-gel electrophoresis

1989 • 62 citations

Turkey erythrocytes possess a membrane-associated inositol 1,4,5-trisphosphate 3-kinase that is activated by Ca2+ in the presence of calmodulin

1987 • 62 citations

Purification and properties of D-myo-inositol 1,4,5-trisphosphate 3-kinase from rat brain. Susceptibility to calpain.

1990 • 61 citations

Molecular cloning and expression of a human brain inositol 1,4,5-trisphosphate 3-kinase

1991 • 53 citations

Mammalian hexokinase 1: Evolutionary conservation and structure to function analysis

1991 • 51 citations

Ca2+/Calmodulin-sensitive inositol 1,4,5-trisphosphate 3-kinase in rat and bovine brain tissues

1988 • 51 citations

Is inositol tetrakisphosphate the second messenger that controls Ca2+ entry into cells?

1992 • 49 citations

Purification and characterization of inositol 1,4,5-trisphosphate 3-kinase from pig aortic smooth muscle

1988 • 48 citations

Neither Arginine nor Histidine Can Carry Out the Function of Lysine-295 in the ATP-Binding Site of p60^src

1986 • 43 citations

Identification of the ATP-binding domain of vaccinia virus thymidine kinase.

1990 • 40 citations

Identification of residues essential for catalysis and binding of calmodulin in rat brain inositol 1,4,5-trisphosphate 3-kinase

1991 • 34 citations

Structural and functional consequences of amino acid substitutions in the second conserved loop of Escherichia coli adenylate kinase.

1991 • 30 citations

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