Enzymology of Microsomal Glutathione S-Transferase

Glutathione S-Transferases

1974 • 17,321 citations

Glutathione Transferases—Structure and Catalytic Activit

1988 • 1,751 citations

The Role of Glutathione and Glutathione S-Transferases in the Metabolism of Chemical Carcinogens and Other Electrophilic Agents

1979 • 1,179 citations

The Isoenzymes of Glutathione Transferase

1985 • 960 citations

Glutathione S-transferases: reaction mechanism, structure, and function

1991 • 334 citations

Reviews in biochemical toxicology

1979 • 274 citations

Microsomal Glutathione Transferase

1983 • 256 citations

Microsomal Glutathione S-Transferase

2005 • 247 citations

Activation of microsomal glutathione S-transferase activity by sulfhydryl reagents

1979 • 168 citations

The distribution of microsomal glutathione transferase among different organelles, different organs, and different organisms

1984 • 160 citations

Characterization of Rat‐Liver Microsomal Glutathione S‐Transferase Activity

1980 • 155 citations

Reviews in biochemical toxicology

1984 • 147 citations

Microsomal glutathione transferase. Primary structure.

1985 • 136 citations

Gene expression of rat and human microsomal glutathione S-transferases.

1988 • 136 citations

Role of microsomal and cytosolic glutathione S-transferases in the conjugation of hexachloro-1:3-butadiene and its possible relevance to toxicity.

1984 • 135 citations

Evidence that rat liver microsomal glutathione transferase is responsible for glutathione-dependent protection against lipid peroxidation

1993 • 119 citations

The identification, solubilization, and characterization of microsome-associated glutathione S-transferases.

1979 • 110 citations

The metabolism and nephrotoxicity of tetrafluoroethylene in the rat

1984 • 107 citations

Structure and function of glutathione transferases

1993 • 107 citations

Bioactivation of xenobiotics by formation of toxic glutathione conjugates

1991 • 105 citations

Oxidative stress-induced activation of microsomal glutathione S-transferase in isolated rat liver

1993 • 97 citations

Activity of rat liver microsomal glutathione transferase toward products of lipid peroxidation and studies of the effect of inhibitors on glutathione-dependent protection against lipid peroxidation

1989 • 89 citations

Metabolism of trichloroethene — in vivo and in vitro evidence for activation by glutathione conjugation

1990 • 84 citations

Bioactivation of tetrachloroethylene. Role of glutathione S-transferase-catalyzed conjugation versus cytochrome P-450-dependent phospholipid alkylation.

1987 • 82 citations

Studies on the activity and activation of rat liver microsomal glutathione transferase, in particular with a substrate analogue series.

1988 • 73 citations

Human microsomal glutathione S-transferase. Its involvement in the conjugation of hexachlorobuta-1,3-diene with glutathione

1989 • 72 citations

Activation of the microsomal glutathione-s-transferase and reduction of the glutathione dependent protection against lipid peroxidation by acrolein

1988 • 65 citations

Activation of rat liver microsomal glutathione transferase by limited proteolysis

1989 • 62 citations

Activation of rat liver microsomal glutathione S-transferase by hydrogen peroxide: Role for protein-dimer formation

1992 • 61 citations

Glutathione conjugates. Immobilized enzyme synthesis and characterization by fast atom bombardment mass spectrometry.

1986 • 60 citations

Radiation inactivation of microsomal glutathione S-transferase.

1986 • 57 citations

Metabolism of the nephrotoxin dichloroacetylene by glutathione conjugation

1989 • 55 citations

Regulation of rat liver microsomal glutathione S-transferase activity by thiol/disulfide exchange

1989 • 50 citations

Enzymic reaction of chlorotrifluoroethene with glutathione: fluorine-19 NMR evidence for stereochemical control of the reaction

1985 • 46 citations

The amount and nature of glutathione transferases in rat liver microsomes determined by immunochemical methods

1983 • 44 citations

The enzymatic reaction of chlorotrifluoroethylene with glutathione

1982 • 44 citations

Activation and inhibition of microsomal glutathione transferase from mouse liver

1988 • 43 citations

Membrane-bound glutathione transferase

1987 • 42 citations

Possible regulation mechanism of microsomal glutathione s-transferase activity in rat liver

1986 • 40 citations

Enzymatic conjugation of hexachloro-1,3-butadiene with glutathione. Formation of 1-(glutathion-S-yl)-1,2,3,4,4-pentachlorobuta-1,3-diene and 1,4-bis(glutathion-S-yl)-1,2,3,4-tetrachlorobuta-1,3-diene.

1988 • 40 citations

Identification of N-acetylcysteine as a new substrate for rat liver microsomal glutathione transferase. A study of thiol ligands.

1994 • 40 citations

Metabolism of hexafluoropropene. Evidence for bioactivation by glutathione conjugate formation in the kidney.

1990 • 36 citations

Stereochemistry of the microsomal glutathione S-transferase catalyzed addition of glutathione to chlorotrifluoroethene

1991 • 35 citations

Inhibition studies on rat liver microsomal glutathione transferase

1990 • 32 citations

A mechanism of haloalkene-induced renal carcinogenesis.

1990 • 31 citations

Human liver microsomal glutathione transferase

1993 • 31 citations

The oligomeric structure of rat liver microsomal glutathione transferase studied by chemical cross-linking

1992 • 31 citations

Transient decrease of liver cytosolic glutathione S-transferase activities in rats given 1,2-dibromoethane or CCl4

1982 • 28 citations

Metabolic activation of the nephrotoxic haloalkene 1, 1, 2-trichloro-3, 3, 3-trifluoro-1-propene by glutathione conjugation

1989 • 27 citations

Activation of microsomal glutathione transferase activity by reactive intermediates formed during the metabolism of phenol

1990 • 27 citations

Properties of the microsomal and cytosolic glutathione transferases involved in hexachloro-1:3-butadiene conjugation

1989 • 25 citations

The gene for the microsomal glutathione S-transferase is on human chromosome 12

1990 • 24 citations

Biosynthesis, bioactivation, and mutagenicity of S-conjugates

1990 • 23 citations

Activation of liver microsomal glutathione S-transferase activity by heating.

1989 • 22 citations

Activation of the microsomal glutathione S-transferase by metabolites of α-methyldopa

1991 • 21 citations

Features of microsomal and cytosolic glutathione conjugation of hexachlorobutadiene in rat liver

1988 • 20 citations

Identification of a hepatic plasma membrane glutathione S-transferase activated by N-ethylmaleimide

1993 • 16 citations

Studies of endogenous inhibitors of microsomal glutathione S-transferase

1982 • 16 citations

Mechanism of activation of rat liver microsomal glutathione transferase by noradrenaline and xanthine oxidase

1992 • 13 citations

Identity of microsomal glutathione-S-transferases

1982 • 11 citations

Studies on the activation of rat liver microsomal glutathione transferase in isolated hepatocytes

1992 • 10 citations

Subcellular distribution of N-ethylmaleimide-stimulatable glutathione S-transferase activity in rat liver. Evidence of localization of glutathione S-transferase in peroxisomal membrane.

1990 • 6 citations

Increase in glutathione disulfide level regulates the activity of microsomal glutathione S-transferase in rat liver.

1989 • 3 citations