Lack of glutathione conjugation to adriamycin in human breast cancer MCF-7/DOX cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Glutathione S-Transferases

1974 • 17,321 citations

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

The Glut athione S-Transferase Supergene Family: Regulation of GST and the Contribution of the lsoenzymes to Cancer Chemoprotection and Drug Resistance Part I

1995 • 3,492 citations

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

1992 • 3,039 citations

THE BIOCHEMISTRY OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG RESISTANCE

1989 • 2,060 citations

High-performance liquid chromatography analysis of nanomole levels of glutathione, glutathione disulfide, and related thiols and disulfides

1980 • 1,179 citations

Regulation of JNK signaling by GSTp

1999 • 1,102 citations

Cell Surface P-Glycoprotein Associated with Multidrug Resistance in Mammalian Cell Lines

1983 • 1,001 citations

Glutathione-Associated Enzymes In Anticancer Drug Resistance

2016 • 864 citations

Overexpression of a novel anionic glutathione transferase in multidrug-resistant human breast cancer cells.

1986 • 791 citations

The ATP-dependent glutathione S-conjugate export pump

1992 • 656 citations

Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs.

1994 • 635 citations

Glutathione Transferases and Cancer

1992 • 548 citations

Purification of glutathione S-transferases from human liver by glutathione-affinity chromatography

1977 • 481 citations

ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein.

1994 • 435 citations

Genetic and biochemical characterization of multidrug resistance

1985 • 405 citations

Doxorubicin - Anticancer Antibiotics

1981 • 402 citations

Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): evidence for cotransport with reduced glutathione.

1998 • 392 citations

Cell biological mechanisms of multidrug resistance in tumors.

1994 • 377 citations

How cancer cells evade chemotherapy: sixteenth Richard and Hinda Rosenthal Foundation Award Lecture.

1993 • 357 citations

Multidrug Resistance1

1988 • 321 citations

Glutathione and related enzymes in multidrug resistance

1996 • 239 citations

Structure and expression of a human class pi glutathione S-transferase messenger RNA.

1987 • 213 citations

Bioreductive activation of mitomycin C by DT-diaphorase

1992 • 158 citations

Expression of recombinant glutathione S-transferase pi, Ya, or Yb1 confers resistance to alkylating agents.

1990 • 148 citations

The role of glutathione-dependent enzymes in drug resistance

1991 • 142 citations

Adenosine triphosphate-dependent transport of doxorubicin, daunomycin, and vinblastine in human tissues by a mechanism distinct from the P-glycoprotein.

1994 • 125 citations

Elevation of the placental glutathione S-transferase form (GST-pi) in tumor tissues and the levels in sera of patients with cancer.

1989 • 106 citations

Enzymatic conjugation of chlorambucil with glutathione by human glutathione S-transferases and inhibition by ethacrynic acid

1991 • 105 citations

Site-directed Mutagenesis of Human Glutathione Transferase P1-1

1995 • 82 citations

Doxorubicin- and Daunorubicin-Glutathione Conjugates, but Not Unconjugated Drugs, Competitively Inhibit Leukotriene C4Transport Mediated byMRP/GS-XPump

1998 • 75 citations

Differential Increases in Glutathione S-Transferase Activities in a Range of Multidrug-Resistant Human Tumor Cell Lines

1989 • 49 citations

Redox chemistry of anthracycline antitumor drugs and use of captodative radicals as tools for its elucidation and control

1991 • 46 citations

Variability of glutathione S-transferase isoenzyme patterns in matched normal and cancer human breast tissue

1994 • 44 citations

Over-expression of P-glycoprotein and glutathione S-transferase PI in MCF-7 cells selected for vincristine resistancein vitro

1992 • 43 citations

Cytoplasmic and Periplasmic Production of Human Placental Glutathione Transferase in Escherichia coli

1995 • 42 citations

Identification of glutathione S-transferase as a determinant of 4-hydroperoxycyclophosphamide resistance in human breast cancer cells

1995 • 42 citations

Conjugation of Glutathione and Other Thiols with Bioreductively Activated Mitomycin C. Effect of Thiols on the Reductive Activation Rate

1994 • 38 citations

A Redox Pathway Leading to the Alkylation of Nucleic Acids by Doxorubicin and Related Anthracyclines: Application to the Design of Antitumor Drugs for Resistant Cancer

1970 • 29 citations

The Glutathione Transferases in Detoxification

1978 • 22 citations

Reaction of Anthracycline Antitumor Drugs with Reduced Glutathione. Formation of Aglycon Conjugates

1994 • 20 citations

GLUTATHIONE TRANSFERASE AND CANCER

1992 • 15 citations

Reduction of daunomycin and 11-deoxydaunomycin with sodium dithionite in DMSO. Formation of quinone methide sulfite adducts and the first NMR characterization of an anthracycline quinone methide

1992 • 13 citations

Cytoplasmic localization of anthracycline antitumor drugs conjugated with reduced glutathione: a possible correlation with multidrug resistance mechanisms.

1998 • 10 citations

Bi[3,5-dimethyl-5-(hydroxymethyl)-2-oxomorpholin-3-yl] (DHM-3 dimer). A water-soluble, one-electron reducing agent

1987 • 7 citations