Cariprazine Treatment of Bipolar Depression: A Randomized Double-Blind Placebo-Controlled Phase 3 Study

Diagnostic and Statistical Manual of Mental Disorders

2013 • 95,283 citations

A RATING SCALE FOR DEPRESSION

1960 • 30,921 citations

A New Depression Scale Designed to be Sensitive to Change

1979 • 12,729 citations

THE ASSESSMENT OF ANXIETY STATES BY RATING

1959 • 10,517 citations

A Rating Scale for Mania: Reliability, Validity and Sensitivity

1978 • 8,000 citations

The Columbia–Suicide Severity Rating Scale: Initial Validity and Internal Consistency Findings From Three Multisite Studies With Adolescents and Adults

2011 • 3,915 citations

The 16-Item quick inventory of depressive symptomatology (QIDS), clinician rating (QIDS-C), and self-report (QIDS-SR): a psychometric evaluation in patients with chronic major depression

2003 • 3,445 citations

A RATING SCALE FOR EXTRAPYRAMIDAL SIDE EFFECTS

1970 • 3,213 citations

A Rating Scale for Drug-Induced Akathisia

1989 • 2,135 citations

The Long-term Natural History of the Weekly Symptomatic Status of Bipolar I Disorder

2002 • 2,037 citations

ECDEU Assessment Manual

1976 • 1,644 citations

Canadian Network for Mood and Anxiety Treatments (<scp>CANMAT</scp>) and International Society for Bipolar Disorders (<scp>ISBD</scp>) 2018 guidelines for the management of patients with bipolar disorder

2018 • 1,333 citations

Efficacy of Olanzapine and Olanzapine-Fluoxetine Combination in the Treatment of Bipolar I Depression

2003 • 891 citations

A Randomized, Double-Blind, Placebo-Controlled Trial of Quetiapine in the Treatment of Bipolar I or II Depression

2005 • 860 citations

Antidepressant-induced mania and cycle acceleration: a controversy revisited

1995 • 600 citations

Efficacy of Quetiapine Monotherapy in Bipolar I and II Depression

2006 • 555 citations

Psychosocial Disability in the Course of Bipolar I and II Disorders

2005 • 550 citations

Lifetime rates of suicide attempts among subjects with bipolar and unipolar disorders relative to subjects with other axis I disorders

1996 • 493 citations

A Double-Blind, Placebo-Controlled Study of Quetiapine and Lithium Monotherapy in Adults in the Acute Phase of Bipolar Depression (EMBOLDEN I)

2010 • 366 citations

Three times more days depressed than manic or hypomanic in both bipolar I and bipolar II disorder¹

2007 • 361 citations

Lurasidone Monotherapy in the Treatment of Bipolar I Depression: A Randomized, Double-Blind, Placebo-Controlled Study

2013 • 308 citations

A Double-Blind, Placebo-Controlled Study of Quetiapine and Paroxetine as Monotherapy in Adults With Bipolar Depression (EMBOLDEN II)

2010 • 300 citations

Lamotrigine in the acute treatment of bipolar depression: results of five double‐blind, placebo‐controlled clinical trials

2008 • 236 citations

Functional Impairment and Disability across Mood States in Bipolar Disorder

2010 • 186 citations

An 8-Week Randomized, Double-Blind, Placebo-Controlled Evaluation of the Safety and Efficacy of Cariprazine in Patients With Bipolar I Depression

2015 • 184 citations

Selective Activation of Postsynaptic 5-HT1A Receptors Induces Rapid Antidepressant Response

1997 • 183 citations

Neuropsychopharmacology

2012 • 182 citations

Cardiovascular mortality in bipolar disorder: a population-based cohort study in Sweden

2013 • 179 citations

The potential role of dopamine D3 receptor neurotransmission in cognition

2013 • 168 citations

Bipolar depression: pharmacotherapy and related therapeutic strategies

2000 • 154 citations

Equally increased risk for metabolic syndrome in patients with bipolar disorder and schizophrenia treated with second‐generation antipsychotics

2008 • 152 citations

Effectiveness of the extended release formulation of quetiapine as monotherapy for the treatment of acute bipolar depression

2011 • 146 citations

Safety and efficacy of adjunctive second-generation antidepressant therapy with a mood stabiliser or an atypical antipsychotic in acute bipolar depression: a systematic review and meta-analysis of randomised placebo-controlled trials

2016 • 129 citations

Prospective study of risk factors for attempted suicide among patients with bipolar disorder

2006 • 127 citations

Epidemiology of DSM-5 bipolar I disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions – III

2016 • 120 citations

Randomised, double-blind, placebo-controlled study of olanzapine in patients with bipolar I depression

2012 • 117 citations

Cariprazine in the treatment of acute mania in bipolar I disorder: A double-blind, placebo-controlled, Phase III trial

2014 • 115 citations

The efficacy and tolerability of cariprazine in acute mania associated with bipolar I disorder: a phase II trial

2014 • 114 citations

Pattern-mixture models with proper time dependence

2003 • 111 citations

Efficacy and Safety of Low- and High-Dose Cariprazine in Acute and Mixed Mania Associated With Bipolar I Disorder

2014 • 107 citations

The Role of Dopamine D3 Receptors in Antipsychotic Activity and Cognitive Functions

2012 • 100 citations

Suicidality in bipolar compared to unipolar depressed inpatients

2000 • 87 citations

Association of obesity and treated hypertension and diabetes with cognitive ability in bipolar disorder and schizophrenia

2014 • 78 citations

Attenuation of anhedonia by cariprazine in the chronic mild stress model of depression

2014 • 71 citations

Implication of dopamine D3 receptor activation in the reversion of Parkinson’s disease-related motivational deficits

2014 • 69 citations

Unmet Clinical Needs in Bipolar Disorder

2003 • 61 citations

Managing the side effects associated with commonly used treatments for bipolar depression

2014 • 59 citations

The application of enhanced parallel gatekeeping strategies

2004 • 48 citations

Recent advances in the treatment of bipolar mania, depression, mixed states, and rapid cycling

2000 • 34 citations

In vitro and in vivo comparison of [³H](+)‐PHNO and [³H]raclopride binding to rat striatum and lobes 9 and 10 of the cerebellum: A method to distinguish dopamine D₃ from D₂ receptor sites: A method to distinguish dopamine D₃ from D₂ receptor sites

2010 • 29 citations

Efficacy of cariprazine on predominant negative symptoms of patients with schizophrenia: post hoc analysis of PANSS data, Marder factors, and cognition

2016 • 8 citations