Managing the side effects associated with commonly used treatments for bipolar depression

Diagnosis and Classification of Diabetes Mellitus

2010 • 14,003 citations

Prevalence of the Metabolic Syndrome Among US Adults

2002 • 6,823 citations

Definition of Metabolic Syndrome

2004 • 5,872 citations

Standards of Medical Care in Diabetes—2013

2012 • 4,307 citations

Bipolar Disorder

2011 • 3,572 citations

Standards of Medical Care in Diabetes—2012

2011 • 2,226 citations

Diagnosis and Classification of Diabetes Mellitus

2004 • 1,629 citations

Evidence-based guidelines for treating bipolar disorder: Revised third edition recommendations from the British Association for Psychopharmacology

2016 • 1,181 citations

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2013

2012 • 1,164 citations

A Double-Blind Placebo-Controlled Study of Lamotrigine Monotherapy in Outpatients With Bipolar I Depression

1999 • 1,056 citations

Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial

2010 • 898 citations

Efficacy of Olanzapine and Olanzapine-Fluoxetine Combination in the Treatment of Bipolar I Depression

2003 • 891 citations

A Randomized, Double-Blind, Placebo-Controlled Trial of Quetiapine in the Treatment of Bipolar I or II Depression

2005 • 860 citations

A Randomized, Placebo-Controlled 12-Month Trial of Divalproex and Lithium in Treatment of Outpatients With Bipolar I Disorder

2000 • 683 citations

The International Society for Bipolar Disorders (ISBD) Task Force Report on Antidepressant Use in Bipolar Disorders

2013 • 670 citations

A Placebo-Controlled 18-Month Trial of Lamotrigine and Lithium Maintenance Treatment in Recently Depressed Patients With Bipolar I Disorder

2003 • 629 citations

A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity‐related risk factors (COR‐II)

2013 • 603 citations

A One-Year Randomized Trial of Lorcaserin for Weight Loss in Obese and Overweight Adults: The BLOSSOM Trial

2011 • 557 citations

Efficacy of Quetiapine Monotherapy in Bipolar I and II Depression

2006 • 555 citations

Antidepressants and Body Weight

2010 • 544 citations

Lithium toxicity profi le: a systematic review and meta-analysis

2012 • 529 citations

Treatment-Emergent Sexual Dysfunction Related to Antidepressants

2009 • 520 citations

Effects of Dietary Patterns on Blood Pressure

1999 • 506 citations

A Behavioral Weight-Loss Intervention in Persons with Serious Mental Illness

2013 • 496 citations

Valproic acid in pregnancy: How much are we endangering the embryo and fetus?

2009 • 495 citations

A Reevaluation of Risk of In Utero Exposure to Lithium

1994 • 470 citations

Management of Obesity in Adults: European Clinical Practice Guidelines

2008 • 430 citations

Evidence-based guidelines for treating bipolar disorder: revised second edition—recommendations from the British Association for Psychopharmacology

2009 • 418 citations

Antipsychotic medications: metabolic and cardiovascular risk.

2007 • 412 citations

Functioning and Disability in Bipolar Disorder: An Extensive Review

2009 • 406 citations

Canadian Network for Mood and Anxiety Treatments (CANMAT) guidelines for the management of patients with bipolar disorder: consensus and controversies

2005 • 396 citations

Adverse effects of antipsychotic medications.

2010 • 392 citations

Metabolic Syndrome and Metabolic Abnormalities in Bipolar Disorder: A Meta-Analysis of Prevalence Rates and Moderators

2013 • 379 citations

Consensus Statement: Consensus Development Conference on Antipsychotic Drugs and Obesity and Diabetes

2004 • 371 citations

A Double-Blind, Placebo-Controlled Study of Quetiapine and Lithium Monotherapy in Adults in the Acute Phase of Bipolar Depression (EMBOLDEN I)

2010 • 366 citations

Three times more days depressed than manic or hypomanic in both bipolar I and bipolar II disorder¹

2007 • 361 citations

Olanzapine Versus Divalproex Sodium for the Treatment of Acute Mania and Maintenance of Remission: A 47-Week Study

2003 • 355 citations

Duloxetine in the Treatment of Major Depressive Disorder

2002 • 338 citations

Rash in Multicenter Trials of Lamotrigine in Mood Disorders

2002 • 334 citations

Lurasidone Monotherapy in the Treatment of Bipolar I Depression: A Randomized, Double-Blind, Placebo-Controlled Study

2013 • 308 citations

Remission Rates Following Antidepressant Therapy With Bupropion or Selective Serotonin Reuptake Inhibitors

2005 • 303 citations

A Double-Blind, Placebo-Controlled Study of Quetiapine and Paroxetine as Monotherapy in Adults With Bipolar Depression (EMBOLDEN II)

2010 • 300 citations

A Randomized, Double-Blind, Placebo-Controlled 26-Week Trial of Aripiprazole in Recently Manic Patients With Bipolar I Disorder

2006 • 289 citations

15 Years of Clinical Experience With Bupropion HCl

2005 • 252 citations

Aripiprazole Monotherapy in Nonpsychotic Bipolar I Depression

2008 • 243 citations

Lurasidone as Adjunctive Therapy With Lithium or Valproate for the Treatment of Bipolar I Depression: A Randomized, Double-Blind, Placebo-Controlled Study

2013 • 242 citations

Aripiprazole Monotherapy for Maintenance Therapy in Bipolar I Disorder

2007 • 241 citations

A Placebo-Controlled Evaluation of Adjunctive Modafinil in the Treatment of Bipolar Depression

2007 • 241 citations

Increased frequency of isolated cleft palate in infants exposed to lamotrigine during pregnancy

2008 • 238 citations

A 7-Week, Randomized, Double-Blind Trial of Olanzapine/Fluoxetine Combination Versus Lamotrigine in the Treatment of Bipolar I Depression

2006 • 209 citations

Antipsychotic-Induced Extrapyramidal Side Effects in Bipolar Disorder and Schizophrenia

2008 • 208 citations

Side effects of antidepressants during long-term use in a naturalistic setting

2013 • 203 citations

The Canadian Network for Mood and Anxiety Treatments (CANMAT) task force recommendations for the management of patients with mood disorders and comorbid conditions.

2012 • 199 citations

A Double-Blind Comparison of Escitalopram and Venlafaxine Extended Release in the Treatment of Major Depressive Disorder

2004 • 186 citations

The International Society for Bipolar Disorders (ISBD) consensus guidelines for the safety monitoring of bipolar disorder treatments

2009 • 177 citations

The Level of Cardiovascular Risk Factors in Bipolar Disorder Equals That of Schizophrenia

2007 • 175 citations

Topiramate versus Bupropion SR when added to mood stabilizer therapy for the depressive phase of bipolar disorder: a preliminary single‐blind study

2002 • 170 citations

Atypical antipsychotics: sleep, sedation, and efficacy.

2004 • 169 citations

Comparison of Combined Bupropion and Naltrexone Therapy for Obesity with Monotherapy and Placebo

2009 • 167 citations

Identifying and treating cognitive impairment in bipolar disorder

2009 • 164 citations

Management of Patients With Treatment-Resistant Depression

2008 • 161 citations

Pharmaceutical approval update.

2010 • 156 citations

Bipolar Disorder — A Focus on Depression

2011 • 152 citations

Effectiveness of the extended release formulation of quetiapine as monotherapy for the treatment of acute bipolar depression

2011 • 146 citations

Akathisia: An Updated Review Focusing on Second-Generation Antipsychotics

2009 • 140 citations

The relationship between bipolar disorder and type 2 diabetes: More than just co-morbid disorders

2012 • 139 citations

Combination Therapy in Hypertension

2010 • 132 citations

A review of valproate in psychiatric practice

2009 • 128 citations

What is the optimal serum lithium level in the long‐term treatment of bipolar disorder – a review?

2008 • 128 citations

Randomized Trial of Sertraline Versus Venlafaxine XR in Major Depression

2005 • 124 citations

Valproate Is Associated with New-Onset Oligoamenorrhea with Hyperandrogenism in Women with Bipolar Disorder

2006 • 123 citations

Metabolic syndrome in bipolar disorder: a cross‐sectional assessment of a Health Management Organization database

2008 • 117 citations

Obesity in Bipolar Disorder: An Overview

2012 • 114 citations

Adjunctive Armodafinil for Major Depressive Episodes Associated With Bipolar I Disorder

2010 • 111 citations

Divalproex in the Treatment of Acute Bipolar Depression

2007 • 108 citations

ASH Position Paper: Dietary Approaches to Lower Blood Pressure

2009 • 106 citations

Findings of a U.S. National Cardiometabolic Screening Program Among 10,084 Psychiatric Outpatients

2010 • 103 citations

Topiramate for prevention of olanzapine associated weight gain and metabolic dysfunction in schizophrenia: A double-blind, placebo-controlled trial

2010 • 101 citations

Efficacy and Safety of Adjunctive Oral Ziprasidone for Acute Treatment of Depression in Patients With Bipolar I Disorder

2011 • 99 citations

Use of insulin sensitizers for the treatment of major depressive disorder: A pilot study of pioglitazone for major depression accompanied by abdominal obesity

2011 • 97 citations

Tolerability profiles of atypical antipsychotics in the treatment of bipolar disorder.

2005 • 95 citations

PPAR-γ Agonism as a Modulator of Mood: Proof-of-Concept for Pioglitazone in Bipolar Depression

2014 • 94 citations

Safety Reporting and Adverse-Event Profile of Mirtazapine Described in Randomized Controlled Trials in Comparison with Other Classes of Antidepressants in the Acute-Phase Treatment of Adults with Depression

2009 • 89 citations

A single blind comparison of lithium and lamotrigine for the treatment of bipolar II depression

2008 • 89 citations

Weight Gain and Glucose Dysregulation with Second-Generation Antipsychotics and Antidepressants: A Review for Primary Care Physicians

2012 • 88 citations

General medical burden in bipolar disorder: findings from the Li<scp>TMUS</scp> comparative effectiveness trial

2013 • 80 citations

Impact of Lamotrigine and Lithium on Weight in Obese and Nonobese Patients With Bipolar I Disorder

2006 • 75 citations

Two 6-Week, Randomized, Double-Blind, Placebo-Controlled Studies of Ziprasidone in Outpatients With Bipolar I Depression

2012 • 72 citations

Olanzapine/fluoxetine combination vs. lamotrigine in the 6-month treatment of bipolar I depression

2008 • 71 citations

Adjunctive Topiramate Therapy in Patients Receiving a Mood Stabilizer for Bipolar I Disorder

2006 • 71 citations

Effects of lamotrigine and lithium on body weight during maintenance treatment of bipolar I disorder

2006 • 70 citations

Antiepileptic drugs and suicidality

2010 • 65 citations

Weight gain with atypical antipsychotics: evidence and insights.

2007 • 65 citations

Impact of Lamotrigine and Lithium on Weight in Obese and Nonobese Patients With Bipolar I Disorder

2006 • 65 citations

Adjunctive stimulant use in patients with bipolar disorder: treatment of residual depression and sedation

2004 • 65 citations

Metabolic syndrome in Italian patients with bipolar disorder

2008 • 61 citations

Insulin dysfunction and allostatic load in bipolar disorder

2011 • 60 citations

Sociodemographic Characteristics and Cardiovascular Risk Factors in Patients With Severe Mental Disorders Compared With the General Population

2006 • 57 citations

Glucose Metabolism in Patients With Schizophrenia Treated With Olanzapine or Quetiapine

2006 • 57 citations

Longitudinal Follow-up of Reproductive and Metabolic Features of Valproate-Associated Polycystic Ovarian Syndrome Features: A Preliminary Report

2006 • 54 citations

Atypical antipsychotics: sedation versus efficacy.

2008 • 54 citations

The Effect of Metformin on Anthropometrics and Insulin Resistance in Patients Receiving Atypical Antipsychotic Agents

2010 • 51 citations

A 24-Week Open-Label Extension Study of Olanzapine-Fluoxetine Combination and Olanzapine Monotherapy in the Treatment of Bipolar Depression

2006 • 50 citations

The diverse roles of anticonvulsants in bipolar disorders.

2003 • 49 citations

Balanced efficacy, safety, and tolerability recommendations for the clinical management of bipolar disorder

2012 • 47 citations

The Diverse Roles of Anticonvulsants in Bipolar Disorders

2003 • 45 citations

A randomised, placebo-controlled 52-week trial of continued quetiapine treatment in recently depressed patients with bipolar I and bipolar II disorder

2012 • 43 citations

C-reactive protein and metabolic syndrome in patients with bipolar disorder compared to patients with schizophrenia.

2010 • 37 citations

Orlistat in Clozapine- or Olanzapine-Treated Patients With Overweight or Obesity

2010 • 36 citations

Lithium Therapy: Limitations and Alternatives in the Treatment of Bipolar Disorders

1995 • 35 citations

Nefrotoxicidade por lítio

2010 • 35 citations

Metabolic Syndrome in Patients Enrolled in a Clinical Trial of Aripiprazole in the Maintenance Treatment of Bipolar I Disorder

2010 • 33 citations

Lamotrigine-associated rash: to rechallenge or not to rechallenge?

2008 • 31 citations

Weight gain and metabolic issues of medicines used for bipolar disorder

2007 • 30 citations

Use of adjunctive stimulants in adult bipolar depression

2012 • 30 citations

A 52-Week, Double-Blind Evaluation of the Metabolic Effects of Aripiprazole and Lithium in Bipolar I Disorder

2011 • 27 citations

Ziprasidone with adjunctive mood stabilizer in the maintenance treatment of bipolar I disorder: Long-term changes in weight and metabolic profiles

2011 • 17 citations

Cardiometabolic Health in Bipolar Disorder

2012 • 8 citations

A Compendium of Antihypertensive Therapy

2011 • 3 citations