Amino Acid Receptors

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

Glutamate, nitric oxide and cell-cell signalling in the nervous system

1991 • 2,406 citations

Glutamate Induces Calcium Waves in Cultured Astrocytes: Long-Range Glial Signaling

1990 • 1,820 citations

Ionic dependence of glutamate neurotoxicity

1987 • 1,811 citations

Excitatory amino acid receptors in the vertebrate central nervous system.

1989 • 1,316 citations

Molecular biology of GABA _A receptors

1990 • 947 citations

DRUG INTERACTIONS AT THE GABA RECEPTOR-IONOPHORE COMPLEX

1982 • 696 citations

Cytosolic calcium oscillators

1988 • 690 citations

Hepatocyte gap junctions are permeable to the second messenger, inositol 1,4,5-trisphosphate, and to calcium ions.

1989 • 596 citations

Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons

1990 • 553 citations

Taurine in the central nervous system and the mammalian actions of taurine

1989 • 548 citations

Two novel GABAA receptor subunits exist in distinct neuronal subpopulations

1989 • 532 citations

Permeation of calcium through excitatory amino acid receptor channels in cultured rat hippocampal neurones.

1990 • 498 citations

Gap Junctional Conductance Is a Simple and Sensitive Function of Intracellular p H

1981 • 481 citations

Pharmacological and functional characteristics of metabotropic excitatory amino acid receptors

1990 • 464 citations

Coupling of Inositol Phospholipid Metabolism with Excitatory Amino Acid Recognition Sites in Rat Hippocampus

1986 • 444 citations

Functional receptors for neurotransmitters on astroglial cells

1987 • 436 citations

The activation of inositol phospholipid metabolism as a signal- transducing system for excitatory amino acids in primary cultures of cerebellar granule cells

1986 • 431 citations

Electrogenic glutamate uptake is a major current carrier in the membrane of axolotl retinal glial cells

1987 • 430 citations

GABAB receptors and their significance in mammalian pharmacology

1989 • 400 citations

Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex

1989 • 390 citations

Acidosis reduces NMDA receptor activation, glutamate neurotoxicity, and oxygen-glucose deprivation neuronal injury in cortical cultures

1990 • 372 citations

Excitatory amino acids directly depolarize rat brain astrocytes in primary culture

1984 • 358 citations

Voltage-Dependent Calcium Channels in Glial Cells

1984 • 347 citations

Glutamate acting on NMDA receptors stimulates neurite outgrowth from cerebellar granule cells

1987 • 316 citations

Ion channel expression by white matter glia: The O-2A glial progenitor cell

1990 • 300 citations

Characterization of L-glutamate uptake into and release from astrocytes and neurons cultured from different brain regions

1982 • 298 citations

Multiple conductance channels in type-2 cerebellar astrocytes activated by excitatory amino acids

1989 • 274 citations

Ion channel expression by white matter glia: The type-1 astrocyte

1990 • 262 citations

Glutamate receptors activate Ca2+ mobilization and Ca2+ influx into astrocytes.

1990 • 239 citations

Subcellular localization of benzodiazepine/GABAA receptors in the cerebellum of rat, cat, and monkey using monoclonal antibodies

1989 • 234 citations

Noise and single channels activated by excitatory amino acids in rat cerebellar granule neurones.

1988 • 223 citations

Pharmacological properties of gamma-aminobutyric acid-, glutamate-, and aspartate-induced depolarizations in cultured astrocytes

1985 • 217 citations

Aspartate, glutamate and γ-aminobutyric acid depolarize cultured astrocytes

1984 • 209 citations

Some properties of unresponsive cells in the cerebral cortex

1967 • 209 citations

Patch-clamp study of gamma-aminobutyric acid receptor Cl- channels in cultured astrocytes.

1988 • 207 citations

Mild acidosis protects hippocampal neurons from injury induced by oxygen and glucose deprivation

1990 • 202 citations

GABA-activated Cl- channels in astrocytes of hippocampal slices

1989 • 198 citations

Evidence for an Astrocyte‐Derived Vasorelaxing Factor with Properties Similar to Nitric Oxide

1990 • 196 citations

Intracellular pH transients of mammalian astrocytes

1989 • 191 citations

The excitatory neurotransmitter glutamate causes filopodia formation in cultured hippocampal astrocytes

1990 • 191 citations

Glutamate opens Na⁺/K⁺ channels in cultured astrocytes

1988 • 190 citations

Astrocyte glutamate receptor activation promotes inositol phospholipid turnover and calcium flux

1986 • 187 citations

Ca2+ influx following receptor activation

1991 • 187 citations

Fluorescence measurement of changes in intracellular calcium induced by excitatory amino acids in cultured cortical astrocytes

1990 • 174 citations

Phosphoinositide metabolism and the control of cell proliferation

1989 • 165 citations

Molecular specialization of astrocyte processes at nodes of Ranvier in rat optic nerve.

1986 • 163 citations

Dye-coupling between glial cells in the guinea pig neocortical slice

1981 • 157 citations

Pharmacologically-distinct subsets of astroglia can be identified by their calcium response to neuroligands

1991 • 156 citations

ATP‐Evoked Ca²⁺ Mobilisation and Prostanoid Release from Astrocytes: P₂‐Purinergic Receptors Linked to Phosphoinositide Hydrolysis

1989 • 156 citations

Activation of glutamate receptors and glutamate uptake in identified macroglial cells in rat cerebellar cultures.

1991 • 149 citations

Multiplicity of GABAA-benzodiazepine receptors

1989 • 149 citations

γ-Aminobutyric acid opens Cl-channels in cultured astrocytes

1987 • 139 citations

Differential intracellular calcium responses to glutamate in type 1 and type 2 cultured brain astrocytes

1991 • 128 citations

Pharmacological characterization of the glutamate receptor in cultured astrocytes

1989 • 123 citations

Astrocytes as eicosanoid‐producing cells

1988 • 122 citations

Subcellular localization of a putative kainate receptor in Bergmann glial cells using a monoclonal antibody in the chick and fish cerebellar cortex

1990 • 115 citations

The non-NMDA receptors: types, protein structure and molecular biology

1990 • 115 citations

Expression of Excitatory Amino Acid Receptors by Cerebellar Cells of the Type‐2 Astrocyte Cell Lineage

1989 • 104 citations

Substance P‐Induced Release of Prostaglandins from Astrocytes: Regional Specialisation and Correlation with Phosphoinositol Metabolism

1991 • 104 citations

Nerve impulse-enhanced release of amino acids from non-synaptic regions of peripheral and central nerve trunks of bullfrog

1975 • 102 citations

Ion channels in schwann and glial cells

1985 • 100 citations

Selective vulnerability of cultured cortical glia to injury by extracellular acidosis

1990 • 100 citations

Glutamate receptor‐linked changes in membrane potential and intracellular Ca²⁺ in primary rat astrocytes

1989 • 90 citations

Glutamate Receptor Subtypes in Cultured Cerebellar Neurons: Modulation of Glutamate and γ‐Aminobutyric Acid Release

1987 • 87 citations

A Novel Type of Glial Cell Associated with Nodes of Ranvier in Rat Optic Nerve

1989 • 87 citations

Evidence that glutamate mediates Axon‐to‐Schwann cell signaling in the squid

1989 • 86 citations

Excitatory Amino Acids Stimulate Inositol Phospholipid Hydrolysis and Reduce Proliferation in Cultured Astrocytes

1990 • 84 citations

Protein kinase C in astrocytes: a determinant of cell morphology

1986 • 82 citations

Expression and Developmental Regulation of a GABA_A Receptor in Cultured Murine Cells of the Oligodendrocyte Lineage

1991 • 81 citations

Effects of MK‐801 on glutamate‐induced swelling of astrocytes in primary cell culture

1990 • 80 citations

GABA release triggered by the activation of neuron‐like non‐NMDA receptors in cultured type 2 astrocytes is carrier‐mediated

1991 • 80 citations

The release of amino acids from nerve during stimulation

1966 • 71 citations

Glutamate stimulates release of Ca2+ from internal stores in astroglia

1990 • 69 citations

Activation of polyphosphoinositide metabolism as a signal‐transducing system coupled to excitatory amino acid receptors in astroglial cells

1989 • 63 citations

Phorbol ester stimulates proliferation of astrocytes in primary culture

1987 • 61 citations

Effect of benzodiazepines and pentobarbital on the GABA‐induced depolarization in cultured astrocytes

1988 • 55 citations

GABA triggers a Cl− efflux from cultured mouse oligodendrocytes

1989 • 55 citations

Subpopulations of rat cerebellar astrocytes in primary culture: Morphology, cell surface antigens and [3H]GABA transport

1986 • 54 citations

Do glia contribute to behaviour? a neuromodulatory review

1989 • 53 citations

Specificity of cell-cell coupling in rat optic nerve astrocytes in vitro.

1990 • 49 citations

Differential distribution of GABAA receptor mRNAs in bovine cerebellum — Localization of α2 mRNA in Bergmann glia layer

1989 • 47 citations

GABA_B receptors couple to G proteins G_o, G^∗_o and G·_i1 but not to G_i2

1990 • 47 citations

Membrane conductance oscillations in astrocytes induced by phorbol ester

1987 • 45 citations

Kainic acid stimulates GABA release from a subpopulation of cerebellar astrocytes

1986 • 42 citations

Growth cones isolated from developing rat forebrain: Uptake and release of GABA and noradrenaline

1985 • 41 citations

Fall in intracellular pH mediated by GABAA receptors in cultured rat astrocytes

1991 • 40 citations

Evidence for GABAB-receptors on cultured astrocytes of rat CNS: autoradiographic binding studies

1990 • 40 citations

Evidence that the depolarization of glial cells by inhibitory amino acids is caused by an efflux of K+ from neurones

1981 • 40 citations

Immunohistochemical localization of a brain isozyme of phospholipase C (PLC III) in astroglia in rat brain

1989 • 35 citations

Lack of Na⁺‐Independent Binding of [³H]GABA or [³H] Muscimol to Particulate Fractions of Cultured Astroblasts

1980 • 35 citations

Amino acid-evoked depolarization of electrically inexcitable (neuroglial?) cells in the guinea pig olfactory cortex slice

1978 • 33 citations

Kainic acid evokes a potassium efflux from astrocytes

1988 • 33 citations

Electrophysiological properties of reactive glial cells in the kainate-lesioned hippocampal slice

1990 • 32 citations

Central Nervous System Astroglial Cells Release Nitrogen Oxide(s) with Vasorelaxant Properties

1991 • 32 citations

Autoradiographic localization of3H-GABA and3H-muscimol binding in rat cerebellar cultures

1980 • 30 citations

Efflux of potassium from neurones excited by glutamate and aspartate causes a depolarization of cultured glial cells

1981 • 29 citations

A new form of transmission?

1989 • 29 citations

Evidence for an interaction between GABAB and glutamate receptors in astrocytes as revealed by changes in Ca2+ flux

1986 • 27 citations

Phencyclidine-induced head-twitch response in rats treated chronically with methysergide

1987 • 26 citations

Glutamate‐Stimulated, Guanine Nucleotide‐Mediated Phosphoinositide Turnover in Astrocytes Is Inhibited by Cyclic AMP

1990 • 25 citations

Kainate-induced stimulation of amino acid release from primary astroglial cultures of the rat hippocampus

1988 • 23 citations

Glial‐Neuronal Interactions

2003 • 23 citations

Central Nervous System Astroglial Cells Release Nitrogen Oxide(s) with Vasorelaxant Properties

1991 • 22 citations

Further characterisation of excitatory amino acid receptors coupled to phosphoinositide metabolism in astrocytes

1990 • 21 citations

Action of baclofen, GABA and antagonists on the membrane potential of cultured astrocytes of rat spinal cord

1990 • 20 citations

Astrocytes are responsive to endothelium-derived relaxing factor (EDRF)

1991 • 19 citations

Inositol 1, 3, 4, 5-tetrakisphosphate and regulation of intracellular calcium

1990 • 17 citations

Cultured rat neurons and astrocytes express immunologically related epitopes of the GABAA/benzodiazepine receptor

1990 • 13 citations

Immunohistochemical studies on the cellular localization of GABAA-receptors in explant cultures of rat central nervous system using a monoclonal antibody

1990 • 10 citations

Deleted Work

1955 • 0 citations