Cytoplasmic 3′ poly(A) addition induces 5′ cap ribose methylation: implications for translational control of maternal mRNA.

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

1993 • 12,238 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

1993 • 4,021 citations

Cyclin synthesis drives the early embryonic cell cycle

1989 • 1,223 citations

Capping of eucaryotic mRNAs

1976 • 1,141 citations

The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency.

1991 • 795 citations

The role of localization of bicoid RNA in organizing the anterior pattern of the Drosophila embryo.

1988 • 736 citations

[25] In vitro RNA synthesis with SP6 RNA polymerase

1987 • 732 citations

A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription

1981 • 703 citations

Normal and mutant human β-globin pre-mRNAs are faithfully and efficiently spliced in vitro

1984 • 679 citations

Function of c-mos proto-oncogene product in meiotic maturation in Xenopus oocytes

1988 • 617 citations

Recognition of cap structure in splicing in vitro of mRNA precursors

1984 • 575 citations

The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation

1989 • 561 citations

5′-Terminal structure and mRNA stability

1977 • 542 citations

Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript.

1994 • 511 citations

A nuclear cap binding protein complex involved in pre-mRNA splicing

1994 • 506 citations

5′-Terminal 7-methylguanosine in eukaryotic mRNA is required for translation

1975 • 481 citations

CPEB is a specificity factor that mediates cytoplasmic polyadenylation during Xenopus oocyte maturation

1994 • 451 citations

Poly(A) elongation during Xenopus oocyte maturation is required for translational recruitment and is mediated by a short sequence element.

1989 • 412 citations

Monomethylated cap structures facilitate RNA export from the nucleus

1990 • 411 citations

A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability.

1987 • 401 citations

Poly(A) addition during maturation of frog oocytes: distinct nuclear and cytoplasmic activities and regulation by the sequence UUUUUAU.

1989 • 332 citations

The 3'-untranslated regions of c-mos and cyclin mRNAs stimulate translation by regulating cytoplasmic polyadenylation.

1994 • 330 citations

Changes in somatic cell nuclei inserted into growing and maturing amphibian oocytes

1968 • 303 citations

Regulated polyadenylation controls mRNA translation during meiotic maturation of mouse oocytes.

1989 • 248 citations

Translational control by cytoplasmic polyadenylation of c-mos mRNA is necessary for oocyte maturation in the mouse.

1994 • 243 citations

Ribosome binding to reovirus mRNA in protein synthesis requires 5′ terminal 7-methylguanosine

1975 • 241 citations

Coordinate Initiation of Drosophila Development by Regulated Polyadenylation of Maternal Messenger RNAs

1994 • 236 citations

Polyadenylation of c-mos mRNA as a control point in Xenopus meiotic maturation

1995 • 232 citations

Translation initiation requires the PAB-dependent poly(A) ribonuclease in yeast

1992 • 212 citations

Meiotic maturation of mouse oocytes triggers the translation and polyadenylation of dormant tissue-type plasminogen activator mRNA.

1987 • 211 citations

Sequence-specific adenylations and deadenylations accompany changes in the translation of maternal messenger RNA after fertilization of Spisula oocytes

1983 • 190 citations

Importance of 5'-terminal blocking structure to stabilize mRNA in eukaryotic protein synthesis.

1977 • 179 citations

Ion-exchange thin-layer chromatography

1965 • 172 citations

Polyadenylation of Maternal RNA of Sea Urchin Eggs After Fertilization

1973 • 166 citations

Translational control by cytoplasmic polyadenylation during Xenopus oocyte maturation: characterization of cis and trans elements and regulation by cyclin/MPF.

1990 • 165 citations

Translational control during early development

1991 • 163 citations

A Single Domain of Yeast Poly(A)-Binding Protein Is Necessary and Sufficient for RNA Binding and Cell Viability

1987 • 158 citations

Translational control by poly(A) elongation during Xenopus development: differential repression and enhancement by a novel cytoplasmic polyadenylation element.

1992 • 156 citations

Blocked, methylated 5′-terminal sequence in avian sarcoma virus RNA

1975 • 153 citations

In the beginning is the end: regulation of poly(A) addition and removal during early development

1990 • 153 citations

Poly(A) metabolism and polysomal recruitment of maternal mRNAs during early Xenopus development

1990 • 147 citations

Maturation-specific polyadenylation and translational control: diversity of cytoplasmic polyadenylation elements, influence of poly(A) tail size, and formation of stable polyadenylation complexes.

1990 • 144 citations

Maturation-specific polyadenylation: in vitro activation by p34cdc2 and phosphorylation of a 58-kD CPE-binding protein.

1991 • 144 citations

Translational control during early dictyostelium development: Possible involvement of poly(A) sequences

1984 • 141 citations

Protein synthesis during maturation promoting factor- and progesterone-induced maturation in Xenopus oocytes

1982 • 138 citations

Nuclear polyadenylation factors recognize cytoplasmic polyadenylation elements.

1994 • 125 citations

Protein synthesis in oocytes of xenopus laevis is not regulated by the supply of messenger RNA

1977 • 117 citations

Most early-variant histone mRNA is contained in the pronucleus of sea urchin eggs

1983 • 113 citations

Role of the 3'-poly(A) sequence in translational regulation of mRNAs in Xenopus laevis oocytes.

1988 • 113 citations

Differential capacity for translation and lack of competition between mRNAs that segregate to free and membrane-bound polysomes

1981 • 113 citations

Cap-specific mRNA (nucleoside-O2'-)-methyltransferase and poly(A) polymerase stimulatory activities of vaccinia virus are mediated by a single protein.

1992 • 108 citations

Translational inactivation of ribosomal protein mRNAs during Xenopus oocyte maturation.

1988 • 106 citations

Influence of 5'-terminal cap structure on the initiation of translation of vaccinia virus mRNA.

1978 • 101 citations

Poly (A) polymerases in the nucleus and cytoplasm of frog oocytes: dynamic changes during oocyte maturation and early development.

1995 • 95 citations

Further analysis of cytoplasmic polyadenylation in Xenopus embryos and identification of embryonic cytoplasmic polyadenylation element-binding proteins.

1994 • 94 citations

Expression of the poly(A)-binding protein during development of Xenopus laevis.

1989 • 94 citations

mRNA(nucleoside-2'-)-methyltransferase from vaccinia virus. Characteristics and substrate specificity

1978 • 93 citations

Mobilization of specific maternal RNA species into polysomes after fertilization in Xenopus laevis.

1985 • 86 citations

The poly(A)‐binding protein facilitates in vitro translation of poly(A)‐rich mRNA

1988 • 84 citations

Inhibition of virus-induced cell transformation by synthetic analogues of S-adenosyl homocysteine

1975 • 75 citations

Poly(A) and translation: development control

1993 • 75 citations

Multiple Sequence Elements and a Maternal mRNA Product Control cdk2 RNA Polyadenylation and Translation during Early Xenopus Development

1994 • 68 citations

Cloning and Characterization of a Xenopus Poly(A) Polymerase

1995 • 65 citations

Cloning and characterization of a Xenopus poly(A) polymerase

1995 • 62 citations

Stimulation of poly(A) tail elongation by the VP39 subunit of the vaccinia virus-encoded poly(A) polymerase.

1993 • 56 citations

Multiple levels of regulation of protein synthesis at fertilization in sea urchin eggs

1985 • 54 citations

Efficient translation of poly(A)-deficient mRNAs in Saccharomyces cerevisiae.

1994 • 49 citations

Translational Potentiation of Messenger RNA with Secondary Structure in Xenopus

1991 • 48 citations

Multiple sequence elements and a maternal mRNA product control cdk2 RNA polyadenylation and translation during early Xenopus development.

1994 • 47 citations

Maturation-Specific Polyadenylation and Translational Control: Diversity of Cytoplasmic Polyadenylation Elements, Influence of Poly(A) Tail Size, and Formation of Stable Polyadenylation Complexes

1990 • 42 citations

The role of cap methylation in the translational activation of stored maternal histone mRNA in sea urchin embryos

1985 • 41 citations

Nuclear Processing of the 3′-Terminal Nucleotides of Pre-U1 RNA in Xenopus laevis Oocytes

1992 • 37 citations

Identification of RNA-binding proteins specific to Xenopus Eg maternal mRNAs: association with the portion of Eg2 mRNA that promotes deadenylation in embryos

1992 • 36 citations

Expression of the Poly(A)-Binding Protein during Development of Xenopus laevis

1989 • 26 citations

Maturation of Xenopus laevis oocyte by progesterone requires poly(A) tail elongation of mRNA

1992 • 25 citations

Antibody-nucleic acid complexes. Immunospecific recognition of 7-methylguanine- and N6-methyladenine-containing 5'-terminal oligonucleotides of mRNA.

1979 • 23 citations

Kinetic and electrophoretic analysis of transmethylation reactions in intact Xenopus laevis oocytes.

1987 • 22 citations

Further Analysis of Cytoplasmic Polyadenylation in Xenopus Embryos and Identification of Embryonic Cytoplasmic Polyadenylation Element-Binding Proteins

1994 • 20 citations

16 Poly(A) Metabolism and Translation: The Closed-loop Model

1996 • 19 citations

17 Dynamics of Poly(A) Addition and Removal during Development

1996 • 17 citations

Translation of maternal histone mRNAs in sea urchin embryos: A test of control by 5′ cap methylation

1987 • 2 citations

Identification of RNA-binding proteins specific to Xenopus Eg maternal mRNAs: association with the portion of Eg2 mRNA that promotes deadenylation in embryos.

1992 • 2 citations