Fibroblast Growth Factor: Molecular and Biological Properties

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

1983 • 1,657 citations

Induction of c-fos gene and protein by growth factors precedes activation of c-myc

1984 • 1,463 citations

Heparin Affinity: Purification of a Tumor-Derived Capillary Endothelial Cell Growth Factor

1984 • 937 citations

Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells

1985 • 911 citations

Human transforming growth factor-α: Precursor structure and expression in E. coli

1984 • 888 citations

Heparin protects basic and acidic FGF from inactivation

1986 • 856 citations

Human Endothelial Cells: Use of Heparin in Cloning and Long-Term Serial Cultivation

1983 • 801 citations

Localisation of a fibroblast growth factor and its effect alone and with hydrocortisone on 3T3 cell growth

1974 • 786 citations

Tumor Growth and Neovascularization: An Experimental Model Using the Rabbit Cornea 2

1974 • 762 citations

An endothelial cell growth factor from bovine hypothalamus: identification and partial characterization.

1979 • 727 citations

Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF.

1985 • 710 citations

Cultured endothelial cells produce heparinlike inhibitor of smooth muscle cell growth

1981 • 685 citations

Isolation of brain fibroblast growth factor by heparin-Sepharose affinity chromatography: identity with pituitary fibroblast growth factor.

1984 • 624 citations

The Influence of the Nerve in Regeneration of the Amphibian Extremity

1952 • 620 citations

Functional role for c-myc in mitogenic response to platelet-derived growth factor

1984 • 578 citations

Trans-filter induction of tubules in mouse metanephrogenic mesenchyme

1956 • 521 citations

Determination of cellular shape by the extracellular matrix and its correlation with the control of cellular growth.

1978 • 487 citations

Effect of Oxygen on Developing Retinal Vessels with Particular Reference to the Problem of Retrolental Fibroplasia

1954 • 486 citations

Vasculae Reactions of Normal and Malignant Tissues in Vivo. I. Vascular Reactions of Mice to Wounds and to Normal and Neoplastic Transplants

1945 • 466 citations

The mode of development of the vascular system of the retina, with some observations on its significance for certain retinal diseases

1948 • 456 citations

Clonal growth of bovine vascular endothelial cells: fibroblast growth factor as a survival agent.

1976 • 423 citations

Relation of vascular proliferation to tumor growth.

1976 • 413 citations

Permissive effect of the extracellular matrix on cell proliferation in vitro.

1980 • 412 citations

Tissue Interactions in Tooth Development

1981 • 406 citations

Heparin Binds Endothelial Cell Growth Factor, the Principal Endothelial Cell Mitogen in Bovine Brain

1984 • 391 citations

Development of the Vertebrate Cornea

1980 • 387 citations

Immunoreactive fibroblast growth factor in cells of peritoneal exudate suggests its identity with macrophage-derived growth factor

1985 • 372 citations

Factors involved in the modulation of cell proliferation in vivo and in vitro: The role of fibroblast and epidermal growth factors in the proliferative response of mammalian cells

1978 • 360 citations

The identification and partial characterization of the fibroblast growth factor receptor of baby hamster kidney cells.

1985 • 352 citations

Basic and acidic fibroblast growth factors interact with the same cell surface receptors.

1986 • 340 citations

Brain-Derived Acidic Fibroblast Growth Factor: Complete Amino Acid Sequence and Homologies

1985 • 335 citations

The Role of extracellular matrix in development

1984 • 334 citations

An endothelial cell-derived growth factor.

1980 • 316 citations

An antiproliferative heparan sulfate species produced by postconfluent smooth muscle cells.

1985 • 315 citations

Differentiation of F9 teratocarcinoma stem cells after transfer of c-fos proto-oncogenes

1984 • 303 citations

Interaction of endothelial cell growth factor with heparin: characterization by receptor and antibody recognition.

1985 • 301 citations

Pure brain-derived acidic fibroblast growth factor is a potent angiogenic vascular endothelial cell mitogen with sequence homology to interleukin 1.

1985 • 294 citations

Effect of fibroblast growth factor and lipoproteins on the proliferation of endothelial cells derived from bovine adrenal cortex, brain cortex, and corpus luteum capillaries

1986 • 273 citations

The effect of fibroblast growth factor on PC12 cells

1985 • 270 citations

Retina- and eye-derived endothelial cell growth factors: partial molecular characterization and identity with acidic and basic fibroblast growth factors

1985 • 268 citations

Purification and characterization of acidic fibroblast growth factor from bovine brain.

1984 • 267 citations

Purification and characterization of heparin-binding endothelial cell growth factors.

1986 • 263 citations

The angiogenic activity of the fibroblast and epidermal growth factor

1979 • 261 citations

Corpus Luteum Angiogenic Factor Is Related to Fibroblast Growth Factor*

1985 • 260 citations

Changes in the distribution of type IV collagen, laminin, proteoglycan, and fibronectin during mouse tooth development

1981 • 243 citations

Possible involvement of protein kinase C and calcium ion in growth factor-induced expression of c-myc oncogene in Swiss 3T3 fibroblasts.

1986 • 241 citations

Vascularization of normal and neoplastic tissues grafted to the chick chorioallantois. Role of host and preexisting graft blood vessels.

1975 • 233 citations

Differentiation and vascularization of the metanephric kidney grafted on the chorioallantoic membrane

1983 • 226 citations

Isolation and partial molecular characterization of pituitary fibroblast growth factor.

1984 • 225 citations

NEUROTROPHIC CONTROL OF LIMB REGENERATION IN THE NEWT*

1974 • 222 citations

Accelerated wound repair, cell proliferation, and collagen accumulation are produced by a cartilage-derived growth factor.

1985 • 221 citations

Effect of heparin on vascular smooth muscle cells. I. Cell metabolism

1985 • 214 citations

Primary structure of bovine brain acidic fibroblast growth factor (FGF)

1985 • 213 citations

The changes in the vascular pattern of the ovary of the albino rat during the estrous cycle

1943 • 212 citations

The growth and morphogenesis of the regenerating forelimb of adult Triturus following denervation at various stages of development

1948 • 210 citations

Heparan sulfates of cultured cells. II. Acid-soluble and -precipitable species of different cell lines

1971 • 208 citations

Control of Bovine Adrenal Cortical Cell Proliferation by Fibroblast Growth Factor. Lack of Effect of Epidermal Growth Factor

1977 • 201 citations

Effect of fibroblast growth factor on the division and fusion of bovine myoblasts.

1976 • 189 citations

Induction of angiogenesis by bovine brain derived class 1 heparin-binding growth factor

1985 • 180 citations

Sulfated proteoglycan synthesis by confluent cultures of rabbit costal chondrocytes grown in the presence of fibroblast growth factor.

1985 • 179 citations

Acidic fibroblast growth factor (FGF) from bovine brain: amino-terminal sequence and comparison with basic FGF.

1985 • 178 citations

Vascular wall growth control: the role of the endothelium.

1981 • 176 citations

Production a corpus luteum angiogenic factor responsible for proliferation of capillaries and neovascularization of the corpus luteum.

1978 • 174 citations

A neuronal cell surface heparan sulfate proteoglycan is required for dorsal root ganglion neuron stimulation of Schwann cell proliferation.

1985 • 171 citations

Mediators in cell growth and differentiation.

1984 • 166 citations

Angiogenic activity from bovine retina: partial purification and characterization.

1981 • 154 citations

Transformation-dependent secretion of a low molecular weight protein by murine fibroblasts.

1978 • 149 citations

Induction of protein kinase C activation and Ca²⁺ mobilization by fibroblast growth factor in Swiss 3T3 cells

1985 • 148 citations

Induction of regeneration of the forelimb of the postmetamorphic frog by augmentation of the nerve supply

1954 • 145 citations

Growth Factors and the Extracellular Matrix

1980 • 142 citations

The Amphibian Eye: Development and Regeneration

1977 • 142 citations

Control mechanisms in cell-type conversion in newt lens regeneration.

1977 • 140 citations

Epidermal growth factor induces redistribution of actin and α-actinin in human epidermal carcinoma cells

1981 • 139 citations

Bovine retina contains three growth factor activities with different affinity to heparin: eye derived growth factor I, II, III

1985 • 139 citations

Interaction of T lymphocytes and macrophages with cultured vascular endothelial cells: Attachment, invasion, and subsequent degradation of the subendothelial extracellular matrix

1984 • 133 citations

Shift in collagen type as an early response to induction of the metanephric mesenchyme.

1981 • 133 citations

The role of fibroblast growth factor and epidermal growth factor in the proliferative response of the corneal and lens epithelium

1977 • 132 citations

The extracellular matrix and the control of proliferation of vascular endothelial and vascular smooth muscle cells

1980 • 129 citations

Mitogenic effect of fibroblast growth factor on early passage cultures of human and murine fibroblasts.

1975 • 129 citations

Isolation of pituitary fibroblast growth factor by fast protein liquid chromatography (FPLC): Partial chemical and biological characterization

1985 • 128 citations

The Endothelial Cells of Large and Small Blood Vessels

1981 • 126 citations

The mechanism and role of hormone-induced clustering of membrane receptors

1980 • 118 citations

Is There a Ubiquitous Growth Factor in the Eye?

1981 • 111 citations

Growth Control in Cultured Mouse Fibroblasts: Induction of the Pleiotypic and Mitogenic Responses by a Purified Growth Factor

1974 • 110 citations

Effect of a platelet endoglycosidase on cell surface associated heparan sulphate of human cultured endothelial and glial cells

1977 • 108 citations

Vascular endothelial cells maintained in the absence of fibroblast growth factor undergo structural and functional alterations that are incompatible with their in vivo differentiated properties.

1979 • 108 citations

Adult tissues contain chemo-attractants for vascular endothelial cells

1980 • 108 citations

Fibroblast growth factor in the human placenta

1985 • 107 citations

Are factors originating from serum, plasma, or cultured cells involved in the growth‐promoting effect of the extracellular matrix produced by cultured bovine corneal endothelial cells?

1983 • 105 citations

Brain fibroblast growth factor: nonidentity with myelin basic protein fragments.

1980 • 102 citations

Selective stimulation by mitogens of incorporation of 35S-methionine into a family of proteins released into the medium by 3T3 cells

1980 • 98 citations

A comparison of the responses of cultured myoblasts and chondrocytes to fibroblast and epidermal growth factors

1977 • 95 citations

Expression of differentiated functions in cancer cells

1982 • 95 citations

Isolation and partial characterization of an endothelial cell growth factor from the bovine kidney: homology with basic fibroblast growth factor

1985 • 93 citations

Comparison of the ability of basement membranes produced by corneal endothelial and mouse-derived Endodermal PF-HR-9 cells to support the proliferation and differentiation of bovine kidney tubule epithelial cells in vitro.

1984 • 90 citations

Bovine brain and pituitary fibroblast growth factors: comparison of their abilities to support the proliferation of human and bovine vascular endothelial cells.

1983 • 90 citations

Bovine fibroblast growth factor: comparison of brain and pituitary preparations.

1982 • 89 citations

The neurite-promoting effect of fibroblast growth factor on PC12 cells

1983 • 88 citations

Denervation effects on newt limb regeneration: DNA, RNA, and protein synthesis

1969 • 86 citations

Growth and adipose differentiation of sheep preadipocyte fibroblasts in serum‐free medium

1983 • 83 citations

Growth requirements of low‐density rabbit costal chondrocyte cultures maintained in serum‐free medium

1984 • 83 citations

Characterization of Cultured Bovine Adrenocortical Cells and Derived Clonal Lines: Regulation of Steroidogenesis and Culture Life Span*

1979 • 80 citations

Degradation of sulfated proteoglycans in the subendothelial extracellular matrix by human platelet heparitinase.

1984 • 78 citations

Concepts of development

1974 • 77 citations

The Effects of the Epidermal and Fibroblast Growth Factors on the Replicative Lifespan of Cultured Bovine Granulosa Cells*

1978 • 74 citations

The role of fibroblast growth factor and the extracellular matrix in the control of proliferation and differentiation of corneal endothelial cells

1981 • 70 citations

An in vitro model to study adipose differentiation in serum-free medium

1982 • 65 citations

Mitogenic effect of a growth factor derived from myelin on denervated regenerates of newt forelimbs

1979 • 63 citations

Effect of a Fibroblast Growth Factor, Insulin, Dexamethasone, and Serum on the Morphology of BALB/c 3T3 Cells

1974 • 61 citations

Cell Biology of the Eye

1982 • 61 citations

Purification in high yield of brain fibroblast growth factor by preparative isoelectric focusing at pH 9.6.

1982 • 60 citations

Stimulation of wound healing, using brain extract with fibroblast growth factor (PGF) activity

1982 • 60 citations

Conditioned medium from endothelial cell cultures can restore the normal phenotypic expression of vascular endothelium maintained in vitro in the absence of fibroblast growth factor

1980 • 59 citations

Stimulation of the release of two glycoproteins from mouse 3T3 cells by growth factors and by agents that increase intralysosomal pH

1981 • 57 citations

Structural and functional alterations in the surface of vascular endothelial cells associated with the formation of a confluent cell monolayer and with the withdrawal of fibroblast growth factor

1979 • 56 citations

Superinduction by cycloheximide of mitogen‐induced secreted proteins produced by Balb/c 3T3 cells

1985 • 55 citations

Effect of substrata and fibroblast growth factor on the proliferation in vitro of bovine aortic endothelial cells

1981 • 55 citations

Influence of the pituitary on Wolffian lens regeneration

1973 • 54 citations

Inactivation of a basement membrane component responsible for cell proliferation but not for cell attachment

1982 • 51 citations

Transdifferentiation of Lens Cells and Its Regulation

1982 • 51 citations

Fibroblast Growth Factor: Its Localisation, Purification, Mode of Action, and Physiological Significance

1975 • 51 citations

Fibroblast Growth Factor Modulates Synthesis of Collagen in Cultured Vascular Endothelial Cells

1982 • 50 citations

Brain-derived fibroblast growth factor: A study of its inactivation

1983 • 50 citations

A human prostatic growth factor (hPGF): Partial purification and characterization

1985 • 49 citations

Stimulation of mitosis in cultured limb blastemata of the newt, Notophthalmus viridescens

1979 • 47 citations

Fibroblast and epidermal growth factors: their uses in vivo and in vitro in studies on cell functions and cell transplantation

1979 • 43 citations

Newt forelimb regeneration blastemas in vitro: Cellular response to explantation and effects of various growth‐promoting substances

1981 • 43 citations

Analysis of histogenesis and regenerative ability of denervated forelimb regenerates of Triturus viridescens

1969 • 37 citations

Biological activity in vivo and in vitro of pituitary and brain fibroblast growth factor.

1984 • 37 citations

Studies on Atherogenesis and Corneal Transplantation Using Cultured Vascular and Corneal Endothelia

1979 • 34 citations

Growth factors and the vessel wall.

1982 • 29 citations

Cellular Specificities of Fibroblast Growth Factor and Epidermal Growth Factor

1978 • 28 citations

A bovine brain fraction with fibroblast growth factor activity inducing articular cartilage regeneration in vivo.

1980 • 27 citations

Bovine pituitary Fibroblast Growth Factor has neurotrophic activity on newt limb regenerates and skeletal muscles in vitro

1981 • 26 citations

Utilization of the chick chorioallantoic membrane for in vitro growth of the embryonic murine kidney

1980 • 24 citations

Fibroblast growth factor and vertebrate regeneration.

1981 • 21 citations

The possible link between receptor phosphorylation and internalization

1985 • 8 citations