Transdifferentiation of Lens Cells and Its Regulation

Radiochemical micro assays for the determination of choline acetyltransferase and acetylcholinesterase activities

1969 • 1,043 citations

Depolarization and calcium entry in squid giant axons

1971 • 729 citations

Lens Differentiation in Vertebrates

1981 • 638 citations

Metaplasia produced in cultures of chick ectoderm by high vitamin A

1953 • 454 citations

The interaction of cyclic nucleotides and calcium in the control of cellular activity.

1975 • 451 citations

Major Problems in Developmental Biology

1966 • 364 citations

An autoradiographic analysis of the time of appearance of neurons in the developing chick neural retina

1974 • 354 citations

Induction of glutamine synthetase in embryonic neural retina: localization in Müller fibers and dependence on cell interactions.

1979 • 274 citations

Membrane Currents in Cardiac Muscle Fibers

1973 • 268 citations

The Stability of the Differentiated State

1968 • 248 citations

Regeneration of the Lens in the Amphibian Eye

1954 • 236 citations

Differentiation of Lens Tissue from the Progeny of Chick Retinal Pigment Cells Cultured In Vitro : A Demonstration of a Switch of Cell Types in Clonal Cell Culture

1973 • 200 citations

chapter 11 Cellular Metaplasia or Transdifferentiaton as a Model for Retinal Cell Differentiation

1980 • 184 citations

The role of retinal pigment cells in regenerating neural retinae of adult salamander eyes

1950 • 166 citations

Electrophoretic and immunoelectrophoretic studies on the soluble proteins in the developing lens of birds

1962 • 159 citations

Lens regeneration from the cornea in Xenopus laevis

1963 • 153 citations

Differentiation of Lens-Like Structures from Newt Iris Epithelial Cells In Vitro

1974 • 152 citations

The Amphibian Eye: Development and Regeneration

1977 • 142 citations

Changes in melanogenesis during the dedifferentiation of chick retinal pigment cells in cell culture

1963 • 142 citations

Control mechanisms in cell-type conversion in newt lens regeneration.

1977 • 140 citations

An analysis of urodelian retinal regeneration: I. Studies of the cellular source of retinal regeneration in Notophthalmus viridescens utilizing ³H‐thymidine and colchicine

1973 • 132 citations

Das Determinationsproblem

1931 • 126 citations

Differentiation of lens in cultures of neural retinal cells of chick embryos

1975 • 126 citations

Chapter 9: Cellular and Subcellular Events in Wolffian Lens Regeneration

1967 • 125 citations

Stem Cells and Tissue Homeostasis

1979 • 116 citations

ELECTRON MICROSCOPIC STUDIES ON LENS REGENERATION

1963 • 112 citations

Induction of the Eye Lens

1980 • 111 citations

Is There a Ubiquitous Growth Factor in the Eye?

1981 • 111 citations

THE EXPRESSION OF DIFFERENTIATION BY CHICKEN LENS EPITHELIUM IN IN VITRO CELL CULTURE*

1971 • 105 citations

Chapter 5 Problems of Differentiation in the Vertebrate Lens

1970 • 103 citations

Neue Versuche zur Wölffschen Linsenregeneration

1914 • 102 citations

Differentiation of Vertebrate Cells

1959 • 101 citations

DNA synthesis and the incorporation of labeled iris cells into the lens during lens regeneration in adult newts

1971 • 95 citations

Transdifferentiation in the labial gland of silk moths: is DNA required for cellular metamorphosis?

1974 • 95 citations

Beitr�ge zur Analyse der Wolff'schen Linsenregeneration I

1930 • 90 citations

A study of DNA synthesis during the transformation of the Iris into lens in the lentectomized newt

1966 • 89 citations

CELLULAR ANALYSIS ON LOCALIZATION OF LENS FORMING POTENCY IN THE NEWT IRIS EPITHELIUM*,**

1971 • 88 citations

Lens antigens in a lens-regenerating system studied by the immunofluorescent technique

1964 • 82 citations

Dynamics of Determination**Dedicated to Karl von Frisch on his eightieth birthday.††Research supported by the Schweizerische Nationalfonds zur Förderung der wissenschaftlichen Forschung.

1966 • 82 citations

Dedifferentiation of iris epithelial cells

1972 • 82 citations

An investigation recording all salamanders which can and cannot regenerate a lens from the dorsal iris

1967 • 81 citations

Control of Tissue Specificity: The Pattern of Cellular Synthetic Activities in Tissue Transformation

1966 • 80 citations

A re-examination of the organ specificity of lens antigens

1968 • 80 citations

Transformation of Iris into Lens in vitro and its Dependency on Neural Retina

1973 • 78 citations

The regeneration of lenses in eyes with intact and regenerating retina in adult Triturus. v. viridescens

1953 • 77 citations

Formation of Lentoids by Dissociated Retinal Cells of the Chick Embryo

1957 • 75 citations

The induction of the primordial germ cells in the urodeles

1974 • 74 citations

Changes in chick lens proteins with aging

1968 • 74 citations

Gamma crystallins in Wolffian lens regeneration demonstrated by immunofluorescence

1966 • 74 citations

Biochemical and immunological studies of lentoid formation in cultures of embryonic chick neural retina and day-old chick lens epithelium

1977 • 73 citations

Activation of ribosomal RNA synthesis in initiation of Wolffian lens regeneration

1969 • 73 citations

Activation of DNA replication in the iris epithelium by lens removal

1969 • 72 citations

Stimulation of lens regeneration from the newt dorsal iris when implanted into the blastema of the regenerating limb

1973 • 70 citations

Über die Regeneration der Linse

1900 • 69 citations

Lens-specific antigens and cytodifferentiation in the developing lens

1968 • 69 citations

Choline acetyl transferase activity in chick embryo neuroretinas during development in ovo and in monolayer cultures

1978 • 66 citations

Beitr�ge zur Analyse der Wolffschen Linsenregeneration. III

1935 • 64 citations

Experimental analysis of the Wolffian lens-regeneration in adult newt, Triturus pyrrhogaster

1941 • 62 citations

Direct evidence for transformation of differentiated iris epithelial cells into lens cells

1974 • 60 citations

Enhancement of differentiation of lens and pigment cells by ascorbic acid in cultures of neural retinal cells of chick embryos

1976 • 59 citations

Elicitation of lens formation from the ‘ventral iris’ epithelium of the newt by a carcinogen, N-methyl-N′-nitro-N-nitrosoguanidine

1973 • 59 citations

IN VITRO ANALYSES OF WOLFFIAN LENS REGENERATION: DIFFERENTIATION OF THE REGENERATING LENS RUDIMENT OF THE NEWT, TRITURUS PYRRHOGASTER¹⁾²⁾

1967 • 58 citations

Entwickelungsphysiologische Studien

1895 • 58 citations

A Chemical Approach to the Problem of the Organizer

1961 • 56 citations

Relationship between crystallin mRNA expression in retina cells and their capacity to re-differentiate into lens cells

1979 • 56 citations

Lentoids in aggregates of embryonic neural retina cells

1981 • 55 citations

Lens regeneration from homoplastic and heteroplastic implants of dorsal iris into the eye chamber of Triturus viridescens and Amblystoma punctatum

1956 • 55 citations

Control of mitotic activity in Wolffian lens regeneration

1971 • 55 citations

Inhibition of lens regeneration in newt eyes by isolating the dorsal iris from the neural retina

1958 • 54 citations

Influence of the pituitary on Wolffian lens regeneration

1973 • 54 citations

Stimulation of melanotic expression in a melanoma cell line by theophylline

1976 • 53 citations

Restitution des Auges nach Exstirpation von Retina und Linse bei Tritonen

1920 • 53 citations

Transdifferentiation of “lentoid” structures in cultures derived from pigmented epithelium was inhibited by collagen

1979 • 52 citations

AN ANALYSIS OF DIFFERENTIATIVE CAPACITY OF PIGMENTED EPITHELIAL CELLS OF ADULT NEWT IRIS IN CLONAL CELL CULTURE

1977 • 52 citations

Macrophage activity in wolffian lens regeneration

1972 • 51 citations

THE DIFFERENTIATION OF PIGMENT CELLS IN CULTURES OF CHICK EMBRYONIC NEURAL RETINAE

1975 • 50 citations

An analysis of urodelian retinal regeneration: IV. Studies of the cellular source of retinal regeneration in Triturus cristatus carnifex using ³H‐thymidine

1973 • 48 citations

An analysis of urodelian retinal regeneration: II. Ultrastructural features of retinal regeneration in Notophthalmus viridescens

1973 • 48 citations

Induction of the Stellate Configuration in Cultured Iris Epithelial Cells by Adenosine and Compounds Related to Adenosine 3′:5′-Cyclic Monophosphate

1973 • 47 citations

Artificial metaplasia of pigmented epithelium into retina in tadpoles and adult frogs.

1972 • 46 citations

Possible demonstration of multipotential nature of embryonic neural retina by clonal cell culture

1979 • 46 citations

Sequential Disappearance of Cell Surface Components during Dedifferentiation in Lens Regeneration

1973 • 45 citations

RESTITUTION OF THE EYE FROM THE IRIS AFTER REMOVAL OF THE RETINA AND LENS TOGETHER WIHT THE EYE-COATS IN THE NEWT,TRITURUS PYRRHOGASTER*

1965 • 45 citations

A study of the oxidation-reduction state of synthetic 3,4-dihydroxy-DL-phenylalanine melanin.

1971 • 41 citations

A demonstration of a switch of cell type in human fetal eye tissues in vitro: Pigmented cells of the iris or the retina can transdifferentiate into lens

1978 • 41 citations

EXPERIMENTAL MANIPULATION OF ALTERNATIVE PATHWAYS OF DIFFERENTIATION IN CULTURES OF EMBRYONIC CHICK NEURAL RETINA

1977 • 39 citations

Isolation and cell-free translation of chick lens crystallin mRNA during normal development and transdifferentiation of neural retina

1978 • 38 citations

Growth of newt iris epithelial cells in vitro

1974 • 37 citations

ÜBER DIE LINSENBILDENDE FÄHIGKEIT DES PIGMENTEPITHELS BEI DIEMYCTYLUS PYRRHOGASTER.

1951 • 37 citations

The in vitro development of lens from cornea of larval Xenopus laevis

1968 • 37 citations

Lens differentiation from the cornea following lens extirpation or cornea transplantation in Xenopus laevis

1973 • 36 citations

CELL SURFACE CHANGES DURING DEDIFFERENTIATION IN THE METAPLASTIC TRANSFORMATION OF IRIS INTO LENS

1972 • 35 citations

Weitere Mittheilungen über die Regeneration der Linse

1902 • 35 citations

Sequence complexity and tissue distribution of chick lens crystallin mRNAs

1978 • 33 citations

An analysis of urodelian retinal regeneration: III. Degradation of extruded melanin granules in Notophthalmus viridescens

1973 • 33 citations

A DEMONSTRATION OF LENS FORMING-CELLS IN NEURAL RETINA IN CLONAL CELL CULTURE

1977 • 32 citations

Influence of embryonic stage on the transdifferentiation of chick neural retina cells in culture.

1978 • 32 citations

Artificial metaplasia of pigmented epithelium into retina in tadpoles and adult frogs

1972 • 32 citations

AGE-DEPENDENT CHANGE IN THE TRANSDIFFERENTIATION ABILITY OF CHICK NEURAL RETINA IN CELL CULTURE*

1979 • 32 citations

Lens regeneration restored to iris membranes when grafted to neural retina environment after cultivation in vitro

1958 • 31 citations

The Acquisition, Maintenance, and Lability of the Differentiated State in Hydra

1968 • 31 citations

Ontogeny and localization of the lens crystallins in Xenopus laevis lens regeneration

1974 • 31 citations

The relationship between the ontogeny of antigens and of the polypeptide chains of the crystallins during chick lens development

1972 • 29 citations

[Detection of delta-crystallins in the adenohypophysis of chick embryos].

1977 • 27 citations

Cell cycle parameters in dedifferentiating iris epithelial cells

1975 • 27 citations

The presence of lens antigens in the intra-ocular tissues of the chick eye

1972 • 27 citations

Die Wirkung des experimentellen Sauerstoffmangels auf die Entwicklung von Tritonkeimen nach beendeter Gastrulation

1950 • 26 citations

Cell transformation in isolated striated muscle of hydromedusae independent of DNA synthesis

1975 • 25 citations

Early events in lens regeneration: Changes in cyclic AMP concentrations during initiation of RNA and DNA synthesis

1974 • 24 citations

Crystallin synthesis in lens differentiation in cultures of neural retinal cells of chick embryos

1979 • 23 citations

An Established Cell Line from the Newt Notophthalmus viridescens

1976 • 23 citations

In vitro initiation in the newt iris of some early molecular events of lens regeneration

1973 • 22 citations

Age-dependent changes in the capacity of transdifferentiation of retinal pigment cells as revealed in clonal cell culture

1981 • 22 citations

Autophagy in Dedifferentiating Newt Iris Epithelial Cells in vitro*

1978 • 22 citations

THE INFLUENCE OF GROWTH-INHIBITING AND GROWTH-PROMOTING MEDIUM CONDITIONS ON CRYSTALLIN ACCUMULATION IN TRANSDIFFERENTIATING CULTURES OF EMBRYONIC CHICK NEURAL RETINA

1980 • 22 citations

Expression of Neuronal Specificities in “Transdifferentiating” Cultures of Neural Retina

1980 • 19 citations

An immuno-fluorescent study of lens regeneration in larval Xenopus laevis

1965 • 19 citations

Structural alterations in cultivated striated muscle cells from anthomedusae (Hydrozoa)

1974 • 18 citations

Influence of embryonic stage on the transdifferentiation of chick neural retina cells in culture

1978 • 18 citations

DNA synthesis during lens regeneration in larval Xenopus laevis

1975 • 18 citations

Cellular Studies of X-Ray Induced Inhibition of Lens Regeneration

1974 • 16 citations

Glucosaminidase and Dedifferentiation of Newt Iris Epithelium

1974 • 16 citations

Synergistic Effects of Adenosine and Compounds Related to Adenosine 3′: 5′-cyclic Monophosphate on Dedifferentiating Iris Epithelial Cells in Culture

1975 • 16 citations

The cell cycle of cultured iris epithelial cells: Its possible role in cell-type conversion

1978 • 16 citations

Levels in Stabilization of Cell Differentiation and Its Experimental Transformation

1977 • 16 citations

Intracellular Levels of Adenosine 3′:5′-Cyclic Monophosphate in the Dorsal Iris of the Adult Newt, During Lens Regeneration

1980 • 16 citations

Delta crystallin accumulation in chick lens epithelial cultures: Dependence on age and genotype

1978 • 15 citations

Regulatory Factors for Lens Fibre Formation in Cell Culture

1979 • 14 citations

The Influence of Hormones and Other Substances on Lens Regeneration in vitro

1980 • 14 citations

The interaction of free radicals in protein and melanin

1964 • 14 citations

[Autoradiographic study of the retinal regeneration in the newt (Triturus cristatus)].

1968 • 13 citations

Pituitary enhancement of wolffian lens regeneration in vitro: Spatial and temporal requirements

1977 • 13 citations

Effect of bovine pituitary hormone preparations on newt lens regeneration in vitro: Stimulation by thyrotropin

1981 • 13 citations

Ricerche sperimentali sulla morfogenesi del cristallino nell'embrione di pollo. Induzione e rigenerazione

1949 • 12 citations

APPEARANCE AND LOCALIZATION OF LENS ANTIGENS DURING THE LENS REGENERATION IN THE ADULT NEWT

1963 • 12 citations

The role of calcium in depigmentation of iris epithelial cells during cell-type conversion

1982 • 11 citations

Immunochemical studies of chick iris

1971 • 11 citations

THE SIMILARITY BETWEEN ANTIGENS IN THE EMBRYONIC LENS AND IN THE LENS REGENERATE OF THE NEWT

1967 • 9 citations

COMPARISON OF NEURONAL AND LENS PHENOTYPE EXPRESSION IN THE TRANSDIFFERENTIATING CULTURES OF NUERAL RETINA WITH DIFFERENT CULTURE MEDIA*

1980 • 7 citations

Zur Entwicklungsphysiologie des Auges der Wirbeltiere

1919 • 6 citations

THE INFLUENCE OF LENS ANTIBODY ON THE LENS REGENERATION IN THE LARVAL NEWT

1964 • 5 citations

Shift in cell type of newt iris epithelial cells in culture

1980 • 4 citations

Crystallin Expression in the TVI Cell Line

1980 • 2 citations