Augmentation of nitric oxide, superoxide, and peroxynitrite production during cerebral ischemia and reperfusion in the rat.

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Localization of nitric oxide synthase indicating a neural role for nitric oxide

1990 • 2,996 citations

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

1988 • 2,572 citations

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

1993 • 2,423 citations

Glutamate, nitric oxide and cell-cell signalling in the nervous system

1991 • 2,406 citations

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures.

1991 • 2,173 citations

Histochemical mapping of nitric oxide synthase in the rat brain

1992 • 1,858 citations

Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase.

1989 • 1,443 citations

The anti‐aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide

1987 • 1,171 citations

Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures

1993 • 1,024 citations

Nitric oxide and the cerebral circulation.

1994 • 540 citations

Nitric oxide synthase: Irreversible inhibition by L-N -Nitroarginine in brain and

1991 • 368 citations

Nitric oxide production during focal cerebral ischemia in rats.

1993 • 272 citations

The Emerging Multifaceted Roles of Nitric Oxide

1995 • 264 citations

Reactive oxygen species and human spermatozoa: Analysis of the cellular mechanisms involved in luminol‐ and lucigenin‐dependent chemiluminescence

1992 • 260 citations

Neonatal Mice Lacking Neuronal Nitric Oxide Synthase Are Less Vulnerable to Hypoxic–Ischemic Injury

1996 • 192 citations

Reperfusion increases neutrophils and leukotriene B4 receptor binding in rat focal ischemia.

1992 • 187 citations

Cerebral endothelial nitric oxide synthase expression after focal cerebral ischemia in rats.

1993 • 182 citations

Nitric oxide production and perivascular nitration in brain after carbon monoxide poisoning in the rat.

1996 • 174 citations

Global Cerebral Ischemia in the Rat: Online Monitoring of Oxygen Free Radical Production Using Chemiluminescence in vivo

1995 • 158 citations

Blockade of nitric oxide formation by mitigates ischemic brain edema and subsequent cerebral infarction in rats

1992 • 142 citations

Nitric Oxide in Neuronal Degeneration

1996 • 140 citations

Cerebral endothelial nitric oxide synthase expression after focal cerebral ischemia in rats.

1993 • 131 citations

Potentiation of nitric oxide formation following bilateral carotid occlusion and focal cerebral ischemia in the rat: in vivo detection of the nitric oxide radical by electron paramagnetic resonance spin trapping

1993 • 114 citations

The effect of nitric oxide synthase inhibition on infarct volume after reversible focal cerebral ischemia in conscious rats.

1993 • 112 citations

The Importance of Superoxide in Nitric Oxide-Dependent Toxicity

1996 • 105 citations

Generation of nitric oxide and superoxide during reperfusion after focal cerebral ischemia in rats

1996 • 92 citations

Time course of nitric oxide synthase activity in neuronal, glial, and endothelial cells of rat striatum following focal cerebral ischemia

1995 • 89 citations

Cloned murine T lymphocytes synthesize a molecule with the biological characteristics of nitric oxide

1990 • 66 citations

EPR spin-trapping study of nitric oxide formation during bilateral carotid occlusion in the rat

1993 • 66 citations

Effects of Nitric Oxide Synthase Inhibition on Cerebral Blood Flow following Bilateral Carotid Artery Occlusion and Recirculation in the Rat

1993 • 59 citations

Brain nitrite production during global ischemia and reperfusion: an in vivo microdialysis study

1996 • 49 citations

Antibodies to intercellular adhesion molecule-1 ameliorate the inflammatory response in acetic acid-induced inflammatory bowel disease.

1995 • 43 citations

Effects of Central Inhibition of Nitric Oxide Synthase on Focal Cerebral Ischemia in Rats

1995 • 39 citations

Nitric oxide synthase inhibitor reduces delayed neuronal death in gerbil hippocampal CA1 neurons after transient global ischemia without reduction of brain temperature or extracellular glutamate concentration

1996 • 24 citations

Cerebral Blood Flow During Inhibition of Brain Nitric Oxide Synthase Activity in Normal, Hypertensive, and Stroke-Prone Rats

1995 • 23 citations

Cerebrospinal Fluid and Peripheral White Blood Cell Response to Acute Cerebral Ischemia

1995 • 21 citations

Macrophages in the Brain: Friends or Enemies?

1994 • 18 citations

Nitric oxide Synthase: From Molecular Biology to Cerebrovascular Physiology

1994 • 18 citations

Neuronal lesions and behavioral modifications in rat following cerebral ischemia and reperfusion

1996 • 9 citations

Role of superoxide dismutase and nitric oxide on the interaction between brain and systemic circulation during brain ischemia

1994 • 7 citations