Specificity and cellular distribution of human polymorphonuclear leucocyte receptors for leukotriene C4.

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response.

1981 • 1,030 citations

Comparative airway and vascular activities of leukotrienes C-1 and D in vivo and in vitro.

1980 • 634 citations

Local Effects of Synthetic Leukotrienes (LTC4, LTD4, and LTB4) in Human Skin

1983 • 585 citations

The human PMN leukocyte chemotactic activity of complex hydroxy-eicosatetraenoic acids (HETEs).

1980 • 518 citations

Leukotrienes C4 and D4 stimulate human endothelial cells to synthesize platelet-activating factor and bind neutrophils.

1986 • 283 citations

Identification of the C(6)-S-conjugate of leukotriene a with cysteine as a naturally occurring slow reacting substance of anaphylaxis (SRS-A). Importance of the 11-cis-geometry for biological activity

1980 • 267 citations

Arachidonic acid metabolism by human monocytes. Studies with platelet-depleted cultures.

1983 • 238 citations

Heterogeneity of human polymorphonuclear leukocyte receptors for leukotriene B4. Identification of a subset of high affinity receptors that transduce the chemotactic response.

1984 • 218 citations

Serine-borate complex as a transition-state inhibitor of gamma-glutamyl transpeptidase.

1978 • 216 citations

Leukotriene C4 affects pulmonary and cardiovascular dynamics in monkey

1982 • 199 citations

Interconversion of leukotrienes catalyzed by purified gamma-glutamyl transpeptidase: concomitant formation of leukotriene D4 and gamma-glutamyl amino acids.

1982 • 180 citations

A NEUTROPHIL-IMMOBILIZING FACTOR DERIVED FROM HUMAN LEUKOCYTES

1972 • 148 citations

Neutrophil plasma membranes. I. High-yield purification of human neutrophil plasma membrane vesicles by nitrogen cavitation and differential centrifugation.

1980 • 133 citations

Leukotriene B4 omega-hydroxylase in human polymorphonuclear leukocytes. Partial purification and identification as a cytochrome P-450.

1985 • 130 citations

Generation of leukotriene C4 from a subclass of mast cells differentiated in vitro from mouse bone marrow.

1982 • 116 citations

Structural and catalytic properties of the solubilized superoxide-generating activity of human polymorphonuclear leukocytes. Solubilization, stabilization in solution, and partial characterization

1979 • 111 citations

Leukotriene C4 binding to rat lung membranes.

1983 • 97 citations

Metabolism of leukotrienes by L-gamma-glutamyl-transpeptidase and dipeptidase from human polymorphonuclear granulocytes.

1985 • 56 citations

IgE-dependent and ionophore-induced generation of leukotrienes by dog mastocytoma cells.

1983 • 42 citations

Identification of specific binding sites for leukotriene C4 in human fetal lung

1984 • 40 citations

Effect of the serine-borate complex on the relative ability of leukotriene C4, D4 and E4 to inhibit lung and brain [3H]leukotriene D4 and [3H]leukotriene C4 binding: Demonstration of the agonists' potency order for leukotriene D4 and leukotriene C4 receptors

1984 • 29 citations

Leukocyte recognition and metabolism of leukotrienes.

1983 • 29 citations

Comparison of the binding affinities of five forms of rat glutathione S-transferases for bilirubin, sulfobromophthalein and hematin

1984 • 26 citations

Leukotriene C4 ([3H] - LTC4) binding to membranes isolated from a hamster smooth muscle cell line (DDTIMF2)

1984 • 22 citations