THE ROLES OF MEMBRANE AND SUBSTRATES IN THE MODULATION OF CYTOCHROME P-450 FUNCTION

Coupling of spin, substrate, and redox equilibriums in cytochrome P450

1976 • 424 citations

Drug interaction with hepatic microsomal cytochrome.

1966 • 335 citations

The resolution and reconstitution of the liver microsomal hydroxylation system

1974 • 223 citations

Substrate interaction with hydroxylase system in liver microsomes

1966 • 183 citations

ω-Oxidation of Long Chain Fatty Acids in Rat Liver

1964 • 175 citations

Preparation of Partially Purified, Lipid-depleted Cytochrome P-450 and Reduced Nicotinamide Adenine Dinucleotide Phosphate-Cytochrome c Reductase from Rat Liver Microsomes

1974 • 146 citations

Glycerol as an Enzyme-Stabilizing Agent: Effects on Aldehyde Dehydrogenase

1972 • 128 citations

Studies on the Kinetics of Cytochrome P-450 Reduction in Rat Liver Microsomes

1970 • 123 citations

Spectrophotometric properties of a triton-clarified steroid 21-Hydroxylase system of adrenocortical microsomes

1965 • 121 citations

Purified liver microsomal cytochrome P-450. Electron-accepting properties and oxidation-reduction potential.

1975 • 120 citations

Participation of the microsomal electron transport system involving cytochrome P-450 in ω-oxidation of fatty acids

1968 • 87 citations

Substrate binding to hepatic microsomal cytochrome P-450. Influence of the microsomal membrane.

1978 • 72 citations

Partial purification and properties of cytochromes P-450 and P-448 from rat liver microsomes

1972 • 72 citations

Temperature-dependent spin equilibrium of microsomal and solubilized cytochrome P-450 from rat liver

1979 • 69 citations

A role for phospholipids in the binding and metabolism of drugs by hepatic microsomes. Use of the fluorescent hydrophobic probe 1-anilinonaphthalene-8-sulphonate

1971 • 68 citations

Studies on P-450

1969 • 64 citations

Cytochrome P-450K of rat kidney cortex microsomes: Further studies on its interaction with fatty acids

1973 • 64 citations

Sedimentation and other properties of the reconstituted liver microsomal mixed-function oxidase system containing cytochrome P-450, reduced triphosphopyridine nucleotide-cytochrome P-450 reductase, and phosphatidylcholine.

1973 • 57 citations

The effects of unsaturated fatty acids on hepatic microsomal drug metabolism and cytochrome P-450

1969 • 56 citations

Effect of substrate on the spin state of cytochrome P-450 in hepatic microsomes

1973 • 46 citations

Electron paramagnetic resonance and temperature dependent spin state studies of ferric cytochrome P-450 from Rhizobium japonicum

1972 • 45 citations

Quantitative analysis of the spin equilibrium of cytochrome LM-2 fraction from rabbit liver microsomes

1978 • 44 citations

Temperature-dependent and -induced spectral characteristics and transitions of liver microsomes

1977 • 19 citations