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Pharmacologic, Toxicologic, and Therapeutic Properties of Anticholinesterase Agents

Data up to Jan 2025

Published1967
Citations53
References945

Total Citations Per Year

Abstract

References (945)

THE REACTION OF ACETYLCHOLINE AND OTHER CARBOXYLIC ACID DERIVATIVES WITH HYDROXYLAMINE, AND ITS ANALYTICAL APPLICATION

1949 • 1,902 citations

Spontaneous subthreshold activity at motor nerve endings

1952 • 1,820 citations

A study of the ‘desensitization’ produced by acetylcholine at the motor end‐plate

1957 • 1,457 citations

A Histochemical Method for Localizing Cholinesterase Activity.

1949 • 1,203 citations

Hypothalamic control of food intake in rats and cats.

1951 • 1,187 citations

Biological and biochemical bases of behavior

1958 • 1,180 citations

Cholinergic and inhibitory synapses in a pathway from motor‐axon collaterals to motoneurones

1954 • 1,172 citations

THE FINE STRUCTURE OF NEURONS

1955 • 861 citations

Über humorale übertragbarkeit der Herznervenwirkung

1921 • 817 citations

Regional Neurochemistry

1962 • 815 citations

CHOLINERGIC AND NON‐CHOLINERGIC NERVE ENDINGS IN RAT BRAIN–I

1962 • 784 citations

Pharmacological studies on presynaptic inhibition

1963 • 765 citations

Chemical and Anatomical Plasticity of Brain

1964 • 757 citations

The discharge of impulses in motor nerve fibres

1929 • 757 citations

ENZYME SECRETION AND THE INCORPORATION OF P32 INTO PHOSPHOLIPIDES OF PANCREAS SLICES

1953 • 757 citations

The action of sympathomimetic amines in animals treated with reserpine

1958 • 746 citations

Serum esterases. 1. Two types of esterase (A and B) hydrolysing p-nitrophenyl acetate, propionate and butyrate, and a method for their determination

1953 • 738 citations

Avoidance Conditioning with Brief Shock and No Exteroceptive Warning Signal

1953 • 665 citations

Iontophoretic studies of neurones in the mammalian cerebral cortex

1963 • 659 citations

SUPPRESSION OF AUDITORY NERVE ACTIVITY BY STIMULATION OF EFFERENT FIBERS TO COCHLEA

1956 • 637 citations

THE ACTION OF MORPHINE AND RELATED SUBSTANCES ON CONTRACTION AND ON ACETYLCHOLINE OUTPUT OF COAXIALLY STIMULATED GUINEA-PIG ILEUM

1957 • 636 citations

THE ACTION OF MORPHINE AND RELATED SUBSTANCES ON CONTRACTION AND ON ACETYLCHOLINE OUTPUT OF COAXIALLY STIMULATED GUINEA‐PIG ILEUM

1997 • 632 citations

The action of botulinum toxin on the neuro‐muscular junction

1949 • 618 citations

Observations on the isolated phrenic nerve diaphragm preparation of the rat

1997 • 618 citations

SYNAPSES IN THE CENTRAL NERVOUS SYSTEM

1956 • 612 citations

THE ACTION OF CERTAIN ESTERS AND ETHERS OF CHOLINE, AND THEIR RELATION TO MUSCARINE

1914 • 604 citations

OBSERVATIONS ON THE ISOLATED PHRENIC NERVE DIAPHRAGM PREPARATION OF THE RAT

1946 • 581 citations

Electrochemical aspects of physiological and pharmacological action in excitable cells. I. The resting cell and its alteration by extrinsic factors.

1958 • 579 citations

SOME FEATURES OF THE SUBMICROSCOPIC MORPHOLOGY OF SYNAPSES IN FROG AND EARTHWORM

1955 • 576 citations

The histochemical localization of cholinesterases in the central nervous system of the rat

1954 • 566 citations

ACETYLCHOLINE METABOLISM OF A SYMPATHETIC GANGLION

1961 • 552 citations

Cholinergic mechanisms in the control of behavior by the brain.

1963 • 542 citations

Injections of drugs into the lateral ventricle of the cat

1954 • 514 citations

Enzymatic Metabolism of Drugs and other Foreign Compounds

1958 • 501 citations

Direct adrenergic and cholinergic stimulation of hypothalamic mechanisms

1962 • 501 citations

Release of acetylcholine at voluntary motor nerve endings

1936 • 480 citations

Some properties of specific cholinesterase with particular reference to the mechanism of inhibition by diethyl p-nitrophenyl thiophosphate (E 605) and analogues

1950 • 475 citations

Über humorale Übertragbarkeit der Herznervenwirkung

1924 • 473 citations

The histochemical identification of acetylcholinesterase in cholinergic, adrenergic and sensory neurons.

1955 • 457 citations

Eating or Drinking Elicited by Direct Adrenergic or Cholinergic Stimulation of Hypothalamus

1960 • 449 citations

Studies on the relationship between chemical constitution and physiological action

1933 • 437 citations

ISOLATION OF SYNAPTIC VESICLES AND STRUCTURAL ORGANIZATION OF THE ACETYLCHOLINE SYSTEM WITHIN BRAIN NERVE ENDINGS*

1963 • 435 citations

Physiological and structural changes at the amphibian myoneural junction, in the course of nerve degeneration

1960 • 432 citations

Reflexogenic Areas of the Cardiovascular System

1958 • 430 citations

Origin and blockade of the synaptic responses of curarized sympathetic ganglia

1961 • 427 citations

Acetylcholine‐sensitive cells in the cerebral cortex

1963 • 416 citations

Cholinesterases and Anticholinesterase Agents

1963 • 409 citations

Central inhibitory action attributable to presynaptic depolarization produced by muscle afferent volleys

1961 • 405 citations

Self-Stimulation of the Brain

1958 • 403 citations

THE EFFECTS OF SOME DRUGS ON THE ELECTRICAL ACTIVITY OF THE BRAIN

1957 • 399 citations

Some Physico-Chemical Factors in Drug Action

1957 • 396 citations

The elimination of enzymatic diffusion artifacts in the histochemical localization of cholinesterases and a survey of their cellular distributions.

1951 • 395 citations

A cholinergic mechanism in the brainstem reticular formation: Induction of paradoxical sleep

1964 • 394 citations

The spontaneous and evoked release of acetylcholine from the cerebral cortex

1963 • 386 citations

The intracellular distribution of glycolytic and other enzymes in rat-brain homogenates and mitochondrial preparations

1960 • 370 citations

Acetylcholine synthesis in different regions of the central nervous system

1948 • 369 citations

Correlation between membrane potential, spike discharge and tension in smooth muscle

1955 • 361 citations

VAGAL AND SYMPATHETIC EFFECTS ON THE PACEMAKER FIBERS IN THE SINUS VENOSUS OF THE HEART

1956 • 359 citations

Cholinesterase-Containing Systems of the Brain of the Rat

1963 • 356 citations

Modern trends in physiology and biochemistry

1952 • 352 citations

Studies on cholinesterase

1943 • 339 citations

Biochemistry of the Developing Nervous System

1956 • 334 citations

A study of spontaneous miniature potentials in spinal motoneurones

1963 • 327 citations

TREATMENT OF MYASTHENIA GRAVIS WITH PHYSOSTIGMINE

1934 • 326 citations

THE FORMATION OF ACETYLCHOLINE. A NEW ENZYME: "CHOLINE ACETYLASE"

1943 • 326 citations

Pharmacology and Nerve-endings (Walter Ernest Dixon Memorial Lecture): (Section of Therapeutics and Pharmacology).

1935 • 324 citations

FUNCTION OF MEDULLATED SMALL-NERVE FIBERS IN MAMMALIAN VENTRAL ROOTS: EFFERENT MUSCLE SPINDLE INNERVATION

1951 • 322 citations

Pharmacological properties of acetylcholine‐sensitive cells in the cerebral cortex

1963 • 321 citations

Supersensitivity of skeletal muscle produced by botulinum toxin

1960 • 319 citations

Increase of Food Intake Induced by Electrical Stimulation of the Lateral Hypothalamus

1952 • 313 citations

Biophysical Aspects of Neuro-muscular Transmission

1956 • 312 citations

Chemical and Molecular Basis of Nerve Activity

1960 • 304 citations

Cytological Distributions and Physiological Functions of Cholinesterases

1963 • 297 citations

Reticular Formation of the Brain

1958 • 293 citations

Intracellular distributions of acetylcholine and choline acetylase

1958 • 288 citations

Pharmacology of organophosphorus cholinesterase inhibitors.

1959 • 286 citations

AN ENZYME IN ANIMAL TISSUES CAPABLE OF HYDROLYZING THE PHOSPHORUS-FLUORINE BOND OF ALKYL FLUOROPHOSPHATES

1946 • 285 citations

The Mode of Neuromuscular Block Caused by Acetylcholine, Nicotine, Decamethonium and Suecinylcholine1

1955 • 283 citations

The distribution of acetylcholine in the peripheral and the central nervous system

1941 • 280 citations

Sympathetic Postganglionic Mechanism

1959 • 280 citations

Pharmacology and Nerve-Endings

1935 • 280 citations

The chemical transmitter at synapses in a sympathetic ganglion

1934 • 279 citations

Reactions of the normal mammalian muscle to acetylcholine and to eserine

1936 • 278 citations

Relations between brain chemistry and problem-solving among rats raised in enriched and impoverished environments.

1962 • 272 citations

The Croonian Lecture - The transmission of impulses from nerve to muscle, and the subcellular unit of synaptic action

1962 • 270 citations

The histochemical differentiation of types of cholinesterases and their localizations in tissues of the cat.

1950 • 267 citations

Pathways of Drug Metabolism,

1956 • 265 citations

Pharmacologic Dissociation of Behavior and EEG "Sleep Patterns" in Dogs: Morphine, N-Allylnormorphine, and Atropine

1952 • 263 citations

Electrical properties and activities of single sympathetic neurons in frogs

1960 • 260 citations

Contributions to the physiology of the lungs

1903 • 256 citations

On the nature of postural reflexes

1929 • 256 citations

CHOLINESTERASES IN THE BLOOD OF MAN

1940 • 256 citations

Über humorale Übertragbarkeit der Herznervenwirkung

1926 • 253 citations

The supersensitivity of denervated structures

1950 • 252 citations

Affinity and Phosphorylation Constants for the Inhibition of Esterases by Organophosphates

1964 • 247 citations

Further observations on the physiology and pharmacology of a sympathetic ganglion

1934 • 246 citations

Depolarization of the motor end‐plate by decamethonium and acetylcholine

1951 • 246 citations

Electrochemical aspects of physiological and pharmacological action in excitable cells. II. The action potential and excitation.

1958 • 240 citations

Pharmacological investigations on a central synapse operated by acetylcholine

1956 • 239 citations

THE MORPHOLOGY AND ACETYLCHOLINE CONTENT OF ISOLATED CEREBRAL CORTICAL SYNAPTIC VESICLES

1965 • 235 citations

Junctional and extra‐junctional acetylcholine receptors in skeletal muscle fibres

1960 • 232 citations

Localization of active spots within the neuromuscular junction of the frog

1956 • 232 citations

Choline acetylase in the central nervous system of man and some other mammals

1956 • 231 citations

The relationship between depolarization and block in the cat's superior cervical ganglion

1953 • 230 citations

An unusual type of sympathetic ganglionic stimulant.

1961 • 229 citations

Studies on the adrenaline-sensitive component of the reticular activating system

1956 • 228 citations

The excitation of Renshaw cells by pharmacological agents applied electrophoretically

1958 • 228 citations

Choline-esterase. An enzyme present in the blood-serum of the horse

1932 • 218 citations

An electrophysiological investigation of mammalian motor nerve terminals

1963 • 214 citations

The differentiation of true and pseudo cholinesterase by organo-phosphorus compounds

1953 • 214 citations

STUDIES ON CHOLINESTERASE

1950 • 211 citations

PRESENT VIEWS ON THE MODE OF ACTION OF ACETYLCHOLINE IN THE CENTRAL NERVOUS SYSTEM

1945 • 210 citations

THE PHARMACOLOGICAL ACTIONS OF POLYMETHYLENE BISTRIMETHYLAMMONIUM SALTS

1949 • 207 citations

Symposium on Muscle Receptors

1963 • 206 citations

ACETYLCHOLINESTERASE

1951 • 205 citations

Alerting Responses and Actions of Atropine and Cholinergic Drugs

1955 • 204 citations

PROCEEDINGS OF THE PHYSIOLOGICAL SOCIETY

1955 • 202 citations

On the negative inotropic effect in the cat's auricle

1953 • 202 citations

Cardiac Cellular Potentials: Effect of Vagal Stimulation and Acetylcholine

1953 • 202 citations

Cholinesterase and succinic dehydrogenase in the central nervous system of the dog

1951 • 198 citations

Pharmacological Inhibition of Acetylcholine Synthesis

1956 • 197 citations

Calcium and synaptic transmission in a sympathetic ganglion

1940 • 194 citations

Biochemical Evidence for the Neural Function of Acetylcholine

1957 • 193 citations

PHARMACOLOGICAL STUDIES UPON NEURONES OF THE LATERAL GENICULATE NUCLEUS OF THE CAT

1962 • 193 citations

Experimental demyelination with organo‐phosphorus compounds

1953 • 191 citations

THE INHIBITION OF THE CONDITIONED RESPONSE AND THE COUNTERACTION OF SCHIZOPHRENIA BY MUSCARINIC STIMULATION OF THE BRAIN

1957 • 191 citations

ACETYLCHOLINESTERASE

1950 • 190 citations

THE EFFECTS OF DIISOPROPYLFLUOROPHOSPHONATE IN SCHIZOPHRENIA AND MANIC DEPRESSIVE PSYCHOSIS

1950 • 188 citations

Toxic Phosphorus Esters

1961 • 187 citations

Principles and Practice of Anesthesiology

1994 • 184 citations

PAM (PYRIDINE-2-ALDOXIME METHIODIDE) THERAPY FOR ALKYLPHOSPHATE POISONING

1958 • 182 citations

Cholinergic and non‐cholinergic transmission in the mammalian spinal cord

1961 • 181 citations

The spontaneous release of acetylcholine from the denervated hemidiaphragm of the rat

1963 • 177 citations

Carbamylation of Acetylcholinesterase

1960 • 176 citations

NERVE ACTIVITY ACCOMPANYING FASCICULATION PRODUCED BY PROSTIGMIN

1940 • 176 citations

The Mechanism of Enzyme Action

1954 • 175 citations

The Effect of Enterogastrone on the Gastric Secretion of the Cat Stimulated toy Continuous Administration of Histamine

1948 • 175 citations

EFFECT OF ESERINE ON NEUROMUSCULAR TRANSMISSION

1942 • 171 citations

Choline acetylase in antero‐ and retro‐grade degeneration of a cholinergic nerve

1956 • 171 citations

Rhythmic electrical activity from isolated cerebral cortex

1949 • 170 citations

The action of d‐tubocurarine and of decamethonium on respiratory and other muscles in the cat

1951 • 168 citations

STUDIES ON CHOLINESTERASE

1945 • 168 citations

Choline ester formation in, and choline esterase activities of, tissues in vitro

1936 • 166 citations

The action potential of the superior cervical ganglion

1935 • 166 citations

A Diazo Coupling Method for the Electron Microscopic Localization of Cholinesterase

1959 • 164 citations

SOME STATISTICAL DATA ON ATYPICAL CHOLINESTERASE OF HUMAN SERUM

1959 • 164 citations

The action of potassium on the superior cervical ganglion of the cat

1936 • 163 citations

Distinction between Acetylcholine-Esterase and Other Choline Ester-splitting Enzymes

1949 • 162 citations

A specific antidote against lethal alkyl phosphate intoxication. II. Antidotal properties

1956 • 161 citations

Motivational Effects of Brain Stimulation and Drugs

2017 • 160 citations

The acetyloholine metabolism of a sympathetic ganglion

1936 • 160 citations

SERINE PHOSPHORIC ACID FROM DIISOPROPYLPHOSPHORYL CHYMOTRYPSIN

1953 • 159 citations

PREGANGLIONIC AND POSTGANGLIONIC STIMULATION OF THE GUINEA‐PIG ISOLATED VAS DEFERENS PREPARATION

1963 • 154 citations

Cholinesterase, succinic dehydrogenase, nucleic acids, esterase and glutathione reductase in sub-cellular fractions from rat brain

1959 • 154 citations

Pyridinium Aldoximes1

1958 • 153 citations

Acetylcholine metabolism in the central nervous system

1939 • 152 citations

The chemical basis of the “ageing process” of DFP-inhibited pseudocholinesterase

1959 • 150 citations

RESPONSES OF THE ISOLATED SYMPATHETIC NERVE‐DUCTUS DEFERENS PREPARATION OF THE GUINEA‐PIG

1961 • 150 citations

ACETYLCHOLINESTERASE

1952 • 150 citations

ENZYME STUDIES ON ISOLATED CELL NUCLEI OF RAT LIVER

1943 • 149 citations

The action of acetylcholine in the supraoptic nucleus of the chloralosed dog

1947 • 146 citations

Histochemical Demonstration of Sites of Choline Esterase Activity.

1948 • 145 citations

Paralysis Following Poisoning by a New Organic Phosphorus Insecticide (Mipafox)

1953 • 144 citations

CHEMICAL TRANSMITTER SUBSTANCES IN BRAIN STEM OF CAT

1961 • 144 citations

Drug action on the brain-stem reticular formation.

1962 • 143 citations

Blood esterases

1942 • 143 citations

Carbamyl Derivatives of Acetylcholinesterase

1961 • 143 citations

STUDIES ON CHOLINESTERASE

1947 • 143 citations

Effect of Undercutting on the Acetylcholinesterase and Choline Acetyltransferase Activity in the Cat's Cerebral Cortex

1963 • 142 citations

HISTOCHEMICAL CORRELATIONS OF ACETYLCHOLINESTERASE AND CATECHOLAMINES IN POSTGANGLIONIC AUTONOMIC NERVES OF THE CAT, RABBIT, AND GUINEA PIG.

1965 • 142 citations

THE MANIFESTATIONS AND TREATMENT OF POISONING DUE TO NERVE GAS AND OTHER ORGANIC PHOSPHATE ANTICHOLINESTERASE COMPOUNDS

1956 • 141 citations

Marked potentiation in mammalian toxicity from simultaneous administration of two anticholinesterase compounds.

1957 • 136 citations

THE ACTION OF ESERINE ON THE BLOOD PRESSURE OF THE RAT

1955 • 136 citations

Ueber die organischen Verbindungen des Phosphors mit dem Stickstoff

1903 • 134 citations

THE EFFECT OF TERTIARY AND QUATERNARY ATROPINE ON CORTICAL ACETYLCHOLINE OUTPUT AND ON THE ELECTROENCEPHALOGRAM IN CATS

1964 • 133 citations

ACTIONS OF DRUGS ON SINGLE NEURONES IN THE BRAIN-STEM

1965 • 133 citations

The release of acetylcholine and of 3‐hydroxytyramine from the caudate nucleus

1964 • 132 citations

A biochemical study of brain microsomes

1959 • 131 citations

The distribution of cholinesterase types in mammalian tissues

1950 • 130 citations

The action of botulinum toxin on motor‐nerve filaments

1954 • 130 citations

Acetylcholine and choline acetyltransferase in the diaphragm of the rat

1964 • 129 citations

Intracellular potentials recorded from a mammalian sympathetic ganglion

1955 • 129 citations

The Physiology of the Human Axillary Apocrine Sweat Gland12

1953 • 128 citations

The kinetics of reactivation, by oximes, of cholinesterase inhibited by organophosphorus compounds

1956 • 124 citations

Central and Synaptic Transmission in the Nervous System (Pharmacological Aspects)

1958 • 123 citations

The effect of diffusional barriers upon the pharmacology of cells within the central nervous system

1958 • 123 citations

Cholinesterases : a study in comparative enzymology

1948 • 122 citations

EFFECTS OF ACETYLCHOLINE ON PHOSPHOLIPIDES IN THE PANCREAS

1954 • 122 citations

Pharmacological experiments on mammalian voluntary muscle, in relation to the theory of chemical transmission

1937 • 122 citations

The development of acetylcholine sensitivity in nerve‐free segments of skeletal muscle

1964 • 121 citations

Effects of changes in ionic environment on the action of acetylcholine and adrenaline on the smooth muscle cells of guinea‐pig taenia coli

1963 • 121 citations

The release of acetylcholine in the isolated rat diaphragm

1961 • 121 citations

RESPONSES OF THE ISOLATED SYMPATHETIC NERVE‐DUCTUS DEFERENS PREPARATION OF THE GUINEA‐PIG

1997 • 119 citations

Pseudo-cholinesterase activity in the central nervous system

1952 • 119 citations

Classification and Comparative Enzymology of the Cholinesterases and Methods for their Determination

1963 • 119 citations

ACTIONS OF DRUGS ON SINGLE NEURONES IN THE CEREBRAL CORTEX

1965 • 118 citations

Motor end‐plate ‘desensitization’ by repetitive nerve stimuli

1959 • 118 citations

Über humorale Übertragung der Erregung von einem Neuron auf das andere

1933 • 118 citations

The effect of guanidine on neuromuscular transmission.

1960 • 118 citations

Physiologische und pharmakologische Untersuchungen an der isolierten Bronchialmuskulatur

1912 • 117 citations

THE HISTOPATHOLOGY OF TRIORTHOCRESYL PHOSPHATE POISONING

1931 • 116 citations

THE AUTONOMIC INNERVATION OF THE GENITO-URINARY SYSTEM

1933 • 115 citations

Mode of Action of the Efferent Olivo-Cochlear Bundle on the Inner Ear

1961 • 114 citations

The Fate of P32 Labelled Diisopropylfluorophosphonate in the Human Body and Its Use as a Labelling Agent in the Study Of The Turnover of Blood Plasma and Red Cells

1954 • 113 citations

Acetylcholinesterase studies on molecular complementariness

1958 • 113 citations

Action of acetylcholine on rabbit auricles in relation to acetylcholine synthesis

1949 • 112 citations

EFFECTS OF ANESTHETICS AND CONVULSANTS ON ACETYLCHOLINE CONTENT OF BRAIN

1950 • 112 citations

Localization of acetylcholinesterase in chick retina during histogenesis

1956 • 111 citations

Metabolism and function of the nerve cell.

1953 • 110 citations

ACETYLCHOLINE METABOLISM AT NERVE-ENDINGS

1957 • 109 citations

The cerebral distributions of a tertiary and a quaternary anticholinesterase agent following intravenous and intraventricular injection.

1956 • 108 citations

The effects of acetylcholine in the heart‐lung preparation including the production of auricular fibrillation

1955 • 107 citations

Muscarinic synapses in the hypothalamus

1962 • 107 citations

Case Showing the Effect of Prostigmin on Myasthenia Gravis

1935 • 107 citations

Studies on the responses of the isolated nictitating membrane of the cat

1958 • 106 citations

The action of acetylcholine and some related substances on conduction in mammalian non‐myelinated nerve fibres

1961 • 106 citations

A specific antidote against lethal alkylphosphate intoxication

1956 • 105 citations

SYNAPTIC MECHANISMS IN SYMPATHETIC GANGLIA

1939 • 105 citations

CHANGES IN MEMBRANE CHARACTERISTICS OF HEART MUSCLE DURING INHIBITION

1956 • 105 citations

Synthesis of acetylcholine in the wall of the digestive tract

1950 • 104 citations

Histochemical demonstration of cholinesterases in the hypothalamus of the dog

1957 • 104 citations

The release of acetylcholine from perfused sympathetic ganglia and skeletal muscles

1956 • 104 citations

THE ELECTROMYOGRAM IN MYASTHENIA GRAVIS

1928 • 103 citations

Cholinesterases. A histochemical contribution to the solution of some functional problems

1961 • 103 citations

Effect of pH on the activity of eel esterase towards different substrates

1958 • 102 citations

Fate of P32-Labeled Malathion in the Laying Hen, White Mouse, and American Cockroach1

1956 • 102 citations

The Enzymic Hydrolysis and Synthesis of Acetylcholine

1951 • 101 citations

The action of acetylcholine on conduction in mammalian non‐myelinated fibres and its prevention by anticholinesterase

1960 • 101 citations

Insecticide Structure and Activity, Insecticidal Activity of Carbamate Cholinesterase Inhibitors

1954 • 101 citations

ACTIONS OF ANTI-CHOLINESTERASES ON ENDPLATE POTENTIAL OF FROG MUSCLE

1949 • 101 citations

The physiological role of acetyl-cholinesterase (AChE) in sympathetic ganglia.

1961 • 100 citations

Molecular complementariness as basis for reactivation of alkyl phosphate-inhibited enzyme

1958 • 99 citations

ACETYLCHOLINESTERASE

1950 • 99 citations

Choline esterase in voluntary muscle

1938 • 99 citations

Intracellular distribution of choline acetylase

1956 • 98 citations

Ueber die Wirkung einiger Gifte auf die Nerven der glandula submaxillaris

1872 • 97 citations

The localization of external or functional acetylcholinesterase at the synapses of autonomic ganglia.

1959 • 97 citations

Über die Cholin‐esterase des Gehirns und der Erythrocyten. zugleich 3. Mitteilung über die Beeinflussung von Fermentreaktionen durch Chemotherapeutica und Pharmaka

1943 • 97 citations

Observations bearing on synaptic transmission by acetylcholine in the spinal cord

1941 • 96 citations

Noradrenaline and adrenaline in mammalian tissues; distribution under normal and pathological conditions with special reference to the endocrine system.

1951 • 96 citations

Slow synaptic responses and excitatory changes in sympathetic ganglia

1964 • 95 citations

The sympathomimetic effect of acetylcholine on the spleen of the cat

1963 • 95 citations

EFFECTS OF INHIBITORS OF CHOLINE ESTERASE ON THE NERVE ACTION POTENTIAL

1946 • 94 citations

The relationship of quaternary ammonium salts to the anionic sites of true and pseudo cholinesterase

1954 • 94 citations

A comparative pharmacological and toxicological study of organic phosphate-anticholinesterase compounds.

1952 • 93 citations

THE ROLE OF ACETYLCHOLINE IN THE CENTRAL NERVOUS SYSTEM

1950 • 93 citations

Metabolism of the Nervous System

1958 • 93 citations

The mechanism of reaction between esterases and phosphorus-containing anti-esterases

1955 • 93 citations

Intracellular Localization of Esterase in Rat Liver

1956 • 92 citations

Changes in configuration of spontaneously discharged spike potentials from smooth muscle of the guinea‐pig's taenia coli. The effect of electrotonic currents and of adrenaline, acetylcholine and histamine

1957 • 92 citations

The Cytological Localization of Intracellular Neuronal Acetylcholinesterase

1959 • 92 citations

Comparison of the effects of inhibition of external, internal and total acetylcholinesterase upon ganglionic transmission.

1959 • 92 citations

The action of decamethonium on normal and denervated mammalian muscle

1951 • 91 citations

Action potentials of normal mammalian muscle. Effects of acetylcholine and eserine

1937 • 90 citations

The responsiveness of individual hypothalamic neurons to microelectrophoretically administered endogenous amines

1963 • 90 citations

EFFECTS OF ESERINE, ACETYLCHOLINE AND ATROPINE ON THE ELECTROCORTICOGRAM

1940 • 89 citations

Synaptic potentials and transmission in sympathetic ganglion

1943 • 89 citations

Chemical nature of the DFP-binding site of pseudocholinesterase

1959 • 89 citations

The motor nerve terminal as the primary focus for drug-in-duced facilitation of neuromuscular transmission.

1957 • 88 citations

Neuromuscular transmission in myasthenia gravis

1953 • 88 citations

Properties and distribution of the enzyme system which synthesizes acetylcholine in nervous tissue

1946 • 87 citations

MODE OF REGENERATION OF ACETYLCHOLINESTERASE IN CHOLINERGIC NEURONS FOLLOWING IRREVERSIBLE INACTIVATION*

1961 • 87 citations

Synergisms and antagonisms between physostigmine and di-isopropyl fluorophosphate in cats.

1946 • 87 citations

New Potent Reactivators of Acetocholinesterase Inhibited by Tetraethyl Pyrophosphate

1958 • 87 citations

FOOD INTAKE AND SPONTANEOUS ACTIVITY OF RATS WITH LESIONS IN THE AMYGDALOID NUCLEI

1952 • 86 citations

The effects of acetylcholine on membrane potential, spike frequency, conduction velocity and excitability in the taenia coli of the guinea‐pig

1958 • 86 citations

The active site of esterases

1959 • 86 citations

756. The reaction of oximes with isopropyl methylphosphono-fluoridate (Sarin)

1956 • 85 citations

Behaviour of cats after intraventricular injections of eserine and DFP

1954 • 85 citations

Unfinished Tasks in the Behavioral Sciences

1965 • 85 citations

A New Interpretation of the Adrenergic Nerve Fiber

1962 • 84 citations

Acetylcholine Release From the Cerebral and Cerebellar Cortices : Its Role in Cortical Arousal

1965 • 84 citations

Enzymatic Activity in the M Band

1959 • 84 citations

XLII.—Physostigmine (eserine). Part III

1925 • 84 citations

Effects of scopolamine and atropine electroencephalographic and behavioral reactions due to hypothalamic stimulation.

1956 • 84 citations

ELECTRICAL STUDIES ON THE PHARMACOLOGY OF AUTONOMIC SYNAPSES II. THE ACTION OF A SYMPATHOMIMETIC DRUG (EPINEPHRINE) ON SYMPATHETIC GANGLIA

1939 • 84 citations

Quantitative Measurement of Inhibition of the Enzymatic Detoxification of Malathion by EPN (ethyl p-nitrophenyl thionobenzenephosphonate).

1957 • 84 citations

Action of eserine and amphetamine on the electrical activity of the rabbit brain.

1957 • 84 citations

Studies on the relationship between chemical constitution and physiological action

1932 • 83 citations

Further observations on the distribution of acetylcholine‐reactive sites in skeletal muscle

1964 • 83 citations

THE SYNTHESIS AND SECRETION OF LIPASE AND RIBONUCLEASE BY PIGEON PANCREAS SLICES

1954 • 83 citations

The excitation of lateral geniculate neurones by quaternary ammonium derivatives

1963 • 83 citations

Acetylcholine depression of cortical neurons

1964 • 83 citations

The pharmacology of sweating.

1955 • 82 citations

Model Reactions of Phosphorus-Containing Enzyme Inactivators. III.1 Interaction of Imidazole, Pyridine and Some of their Derivatives with Dialkyl Halogeno-phosphates

1953 • 82 citations

Pharmacological receptors and general permeability phenomena of cell membranes

1965 • 82 citations

The nature of synaptic transmission in a sympathetic ganglion

1944 • 82 citations

Effects of cholinergic drugs on hypothalamic self-stimulation response rates of dogs

1963 • 80 citations

The Reactivation of Acetylcholinesterase Inhibited by Tetraethyl Pyrophosphate and Diisopropyl Fluorophosphate1

1955 • 80 citations

The physiological action of physostigmine and its action on denervated skeletal muscle

1915 • 80 citations

The Effect of Certain Autonomic Drugs on the Action Potentials of the Sinus Nerve

1952 • 79 citations

CHEMICAL REACTIVATION OF PHOSPHORYLATED HUMAN AND BOVINE TRUE CHOLINESTERASES

1956 • 79 citations

THE REACTION OF CHOLINESTERASE WITH DIISOPROPYL FLUOROPHOSPHATE

1951 • 78 citations

The effect of selective inhibition of pseudocholinesterase on the spontaneous and evoked activity of the cat's cerebral cortex

1957 • 78 citations

Antidromic activity in the rat phrenic nerve—diaphragm preparation

1964 • 78 citations

THE ANTICHOLINESTERASE ACTIVITY OF SOME ANTIADRENALINE AGENTS

1960 • 78 citations

The Analgetic Action of Morphine, Eserine and Prostigmine Studied by a Modified Hardy-Wolff-Goodell Method.

1945 • 78 citations

The Effects of Acetyleholine, Decamethonium and Suneeinylcholine on Neuromuscular Transmission in the Rat

1955 • 78 citations

Oximes Antagonistic to Inhibitors of Cholinesterase

1964 • 77 citations

THE SYSTEMIC NERVOUS AFFINITY OF TRIORTHOCRESYL PHOSPHATE (JAMAICA GINGER PALSY)

1942 • 77 citations

An electrophysiologic study of the neuromuscular junction in myasthenia gravis

1961 • 76 citations

Localization of Acetylcholinesterase in the Neurohypophysis and its Functional Implications.

1961 • 76 citations

THE RELEASE OF ACETYLCHOLINE FROM MAMMALIAN MOTOR NERVE ENDINGS

1960 • 76 citations

ELECTROPHYSIOLOGY OF ELECTRIC ORGAN IN GYMNOTUS CARAPO

1959 • 75 citations

Recherches Sur La Physiologie Et La Pharmacologie Du Système Nerveux Autonome

1936 • 75 citations

Proposed Mechanism of Action of Hydrolytic Enzymes

1957 • 75 citations

Protection of cholinesterase against irreversible inactivation by di-isopropyl fluorophosphate in vitro.

1946 • 74 citations

THE EFFECT OF ANTI‐CHOLINESTERASE AGENTS ON THE RAT'S BLOOD PRESSURE

1955 • 74 citations

The Active Site of Acetylcholinesterase and Related Esterases and its Reactivity towards Substrates and Inhibitors

1963 • 73 citations

Studies on cholinesterase

1946 • 73 citations

Bimodal response of sympathetic ganglia to acetylcholine following eserine or repetitive preganglionic stimulation.

1962 • 73 citations

Responses of isolated curarized sympathetic ganglia

1952 • 73 citations

On the mechanism of the autacoid function of parasympathetic nerves

1934 • 73 citations

Effect of Drugs on Contractions of Vertebrate Smooth Muscle

1964 • 72 citations

Nature and Spatial Relationship of the Prosthetic Chemical Groups Required for Maximal Muscarinic Action

1948 • 72 citations

THE PHARMACOLOGICAL ACTION OF SOME ANALOGUES OF PHYSOSTIGMINE

1931 • 72 citations

Structure-Activity Relationships of the Organophosphorus Anticholinesterase Agents

1963 • 72 citations

Response of individual olfactory nerve cells to microelectrophoretically administered chemical substances

1963 • 71 citations

A COMPARISON OF CHOLINESTERASE DISTRIBUTION IN THE CEREBELLUM OF SEVERAL SPECIES*

1964 • 71 citations

Pharmacological experiments on the release of the sympathetic transmitter

1963 • 71 citations

Chemical Factors Controlling Nerve Activity

1961 • 70 citations

Action of drugs on carotid body and sinus.

1955 • 70 citations

Action potentials of isolated mammalian sympathetic ganglia

1952 • 70 citations

A New Series of Cholinesterase Inhibitors*

1954 • 70 citations

Formation, Storage, and Liberation of Acetylcholine

1963 • 69 citations

The Correlation between the Occurrence and Localization of Acetylcholinesterase-rich Cell Bodies in the Stellate Ganglion and the Outflow of Cholinergic Sweat Secretory Fibres to the Fore Paw of the Cat

1963 • 69 citations

On the Connection between Chemical Constitution and Physiological Action; with special reference to the Physiological Action of the Salts of the Ammonium Bases derived from Strychnia, Brucia, Thebaia, Codeia, Morphia, and Nicotia.

1868 • 69 citations

Identification of Acetylcholine and Related Esters of Biological Origin

1963 • 69 citations

PROTECTION AGAINST THE LETHAL EFFECTS OF ORGANO‐PHOSPHATES BY PYRIDINE‐2‐ALDOXIME METHIODIDE

1957 • 69 citations

Augmentation of the behavioral effects of amphetamine by atropine.

1961 • 69 citations

The essentiality of acetylcholinesterase in conduction

1953 • 68 citations

The Role of Phosphatidic Acid and Phospho-Inositide in Transmembrane Transport Elicited by Acetylcholine and Other Humoral Agents

1960 • 68 citations

PROTECTION AGAINST LETHAL ORGANOPHOSPHATE POISONING BY QUATERNARY PYRIDINE ALDOXIMES

1959 • 67 citations

Formation of potent inhibitors of AChE by reaction of pyridinaldoximes with isopropyl methylphosphonofluoridate (GB)

1959 • 67 citations

Effect of Curare on Conduction in Myelinated, Isolated Nerve Fibres of the Frog

1960 • 66 citations

Induced Innervation of End-plate Free Muscle Segments

1962 • 66 citations

Cholinesterase Content of Certain Regions of the Spinal Cord as Judged by Histochemical and Cartesian Diver Technique

1958 • 66 citations

Potentiation of Toxicity of Malathion by Triorthotolyl Phosphate.

1959 • 65 citations

The action on nicotine-induced tremors of substances effective in Parkinsonism.

1951 • 64 citations

Treatment of Poisoning by Anticholinesterase Insecticides in the Rat

1961 • 64 citations

Effects of acetylcholine on axonal conduction of lobster nerve

1963 • 64 citations

Reversible block of axonal conduction by curare after treatment with cobra venom

1961 • 64 citations

THE CHOLINERGIC BLOCKING ACTION OF ADRENERGIC BLOCKING AGENTS IN THE PHARMACOLOGICAL ANALYSIS OF AUTONOMIC INNERVATION

1963 • 64 citations

Potential changes evoked in a curarized sympathetic ganglion by presynaptic volleys of impulses

1950 • 64 citations

AN ELECTRICAL HYPOTHESIS OF SYNAPTIC AND NEURO‐MUSCULAR TRANSMISSION

1946 • 64 citations

Action of Ions on Choline Esterase

1940 • 63 citations

Some Indications of Cerebral Humoral Mechanisms

1953 • 63 citations

THE ACTION OF 5‐HYDROXYTRYPTAMINE ON THE NICTITATING MEMBRANE AND ON THE SUPERIOR CERVICAL GANGLION OF THE CAT

1956 • 63 citations

THE ACTION OF DRUGS ON THE CIRCULAR MUSCLE STRIP FROM THE GUINEA‐PIG ISOLATED ILEUM

1963 • 63 citations

Reactivation of Phosphorylated Acetylcholinesterase

1963 • 62 citations

Acetylcholine and the sympathetic innervation of the spleen

1961 • 62 citations

NEUROMUSCULAR FACILITATION AND ANTIDROMIC DISCHARGES IN MOTOR NERVES: THEIR RELATION TO ACTIVITY IN MOTOR NERVE TERMINALS

1960 • 62 citations

Effects of Complex Environment and Blindness on Rat Brain

1963 • 62 citations

In vitro reactivation and “ageing” of tabun-inhibited blood cholinesterases

1963 • 62 citations

An analysis of the central and peripheral components of respiratory failure produced by anticholinesterase poisoning in the rabbit

1954 • 62 citations

The immediate and delayed effects of diisopropylfluorophosphate injected into the supraoptic nuclei of dogs

1950 • 62 citations

Myasthenia gravis

1958 • 62 citations

The direct action of prostigmine on skeletal muscle; its relationship to the choline esters.

1946 • 62 citations

SOME EFFECTS OF PROSTIGMINE AND ACETYLCHOLINE ON CORTICAL POTENTIALS

1942 • 61 citations

The action of eserine and related compounds and of acetylcholine on the central nervous system

1937 • 61 citations

EFFECT OF NICOTINHYDROXAMIC ACID METHIODIDE ON HUMAN PLASMA CHOLINESTERASE INHIBITED BY ORGANOPHOSPHATES CONTAINING A DIALKYLPHOSPHATO GROUP

1955 • 61 citations

GENERALITY OF THE ROLE OF ACETYLCHOLINE IN NERVE AND MUSCLE CONDUCTION

1947 • 61 citations

A STUDY OF DENERVATED MAMMALIAN SKELETAL MUSCLE

1937 • 61 citations

BIOCHEMICAL ASPECTS OF THE ACTIONS OF PSYCHOTOMIMETIC DRUGS.

1965 • 61 citations

Antichounergic Psychotomimetic Agents

1962 • 60 citations

Pharmakologische Untersuchungen über das Physostigmin und Calabarin

1876 • 60 citations

The Mode of Action of Acetylcholine: A Theory Extended to a Hypothesis on the Mode of Action of other Biologically Active Substances.

1953 • 60 citations

Demonstration of Increased Permeability as a Factor in the Effect of Acetylcholine on the Electrical Activity of Venom-Treated Axons

1963 • 59 citations

The effect of some drugs on hippocampal arousal

1962 • 59 citations

INTRAVENTRICULAR INJECTION OF ACETYLCHOLINE AND ESERINE IN MAN

1936 • 59 citations

AMINO ACID AND PROTEIN METABOLISM OF THE BRAIN—VIII* THE RECOVERY OF CHOLINESTERASE IN THE NERVOUS SYSTEM OF THE FROG AFTER INHIBITION

1961 • 59 citations

SOME PHARMACOLOGICAL PROPERTIES OF THE CIRCULAR AND LONGITUDINAL MUSCLE STRIPS FROM THE GUINEA‐PIG ISOLATED ILEUM

1963 • 59 citations

Studies on the Relationship between Chemical Constitution and Physiological Action

1926 • 58 citations

CHOLINESTERASES IN SYMPATHETIC FIBERS AND GANGLIA

1945 • 58 citations

Neurohumors in hypothalamic substrates of reward

1964 • 58 citations

A NEW EXPERIMENTAL APPROACH TO THE PHYSIOLOGY AND PHARMACOLOGY OF THE BRAIN

1965 • 58 citations

Cholinesterases of the tissues and sera of rabbits

1953 • 58 citations

Turnover Time of Acetylcholinesterase

1961 • 58 citations

The effects of acetylcholine and other drugs on the isolated superior cervical ganglion

1956 • 58 citations

Pharmacological Aspects of Parkinsonism

1964 • 57 citations

THE PRESYNAPTIC ELEMENT IN NEUROMUSCULAR TRANSMISSION*

1959 • 57 citations

THE PENETRATION OF 2-PAM-C14 INTO BRAIN AND THE EFFECT OF CHOLINESTERASE INHIBITORS ON ITS TRANSPORT.

1964 • 57 citations

Zur Pathogenese und Therapie der Myasthenia gravis pseudoparalytica

1932 • 56 citations

Über das Schicksal des Acetylcholins im Blute

1928 • 56 citations

THE RELATIONSHIP BETWEEN THE CHEMICAL STRUCTURE AND NEUROTOXICITY OF ALKYL ORGANOPHOSPHORUS COMPOUNDS

1960 • 56 citations

On the Physiology of the Salivary Secretion

1889 • 56 citations

Distribution of Acetocholinesterase in the Ganglion Cells of Various Sympathetic Ganglia

1960 • 56 citations

EFFECTS OF SCOPOLAMINE ON A MULTIPLE SCHEDULE1,2

1958 • 56 citations

ACTION OF PROSTIGMINE AND ACETYLCHOLINE ON RESPIRATION

1938 • 56 citations

FURTHER ANALYSIS OF RELATIONSHIP BETWEEN END-PLATE POTENTIAL AND END-PLATE CURRENT

1960 • 56 citations

Electrical activity in electric tissue I. The difference between tertiary and quaternary nitrogen compounds in relation to their chemical and electrical activities

1955 • 55 citations

THE INHIBITION OF CHOLINESTERASES BY ANTAGONISTS OF ACETYLCHOLINE AND HISTAMINE

1954 • 55 citations

Organic phosphate insecticide poisoning

1958 • 55 citations

Ability of venoms to render squid axons sensitive to curare and acetylcholine

1963 • 55 citations

The relationship between cholinesterase activity and brain permeability.

1951 • 55 citations

Function of the Uncrossed Efferent Olivo-cochlear Fibres in the Cat

1963 • 54 citations

The nicotinic action of substances supposed to be purely smooth‐muscle stimulating

1949 • 54 citations

Anticholinesterase Agents

1963 • 54 citations

A specific antidote against lethal alkyl phosphate intoxication. V. Antidotal properties

1957 • 54 citations

Fine structure of the active surface of cholinesterases and the mechanism of enzymatic ester hydrolysis

1955 • 54 citations

CURARIZATION, FATIGUE AND WEDENSKY INHIBITION

1937 • 54 citations

Histochemical demonstration of reversible anticholinesterase action at selective cellular sites in vivo.

1957 • 54 citations

CONFIGURATIONAL ANALYSIS OF 4-FORMYL-1-METHYLPYRIDINIUM IODIDE OXIMES AND ITS RELATIONSHIP TO A MOLECULAR COMPLEMENTARITY THEORY ON THE REACTIVATION OF INHIBITED ACETYLCHOLINESTERASE

1961 • 54 citations

Removal of acetylcholine from a limited volume by diffusion

1955 • 53 citations

Localization of Specific Cholinesterase in Ocular Tissues of the Cat*

1952 • 53 citations

EFFECTS OF CHRONIC REDUCTIONS IN BRAIN CHOLINESTERASE ACTIVITY ON ACQUISITION AND EXTINCTION OF A CONDITIONED AVOIDANCE RESPONSE

1961 • 52 citations

Acute tetraethylpyrophosphate poisoning in cats and its modification by atropine or hyoscine

1952 • 52 citations

Acetylcholine Release at Parasympathetic Synapses

1950 • 52 citations

PHARMACOLOGY OF CENTRAL INHIBITORY SYNAPSES

1965 • 51 citations

THE MODE OF ACTION OF NEOSTIGMINE AND PHYSOSTIGMINE ON THE GUINEA‐PIG TRACHEALIS MUSCLE

1963 • 51 citations

Structure-Activity Relationships of the Reversible Anticholinesterase Agents

1963 • 51 citations

Further Studies on the Pharmacology of Certain Phenol Esters with Special Reference to the Relation of Chemical Constitution and Physiologic Action.

1932 • 51 citations

On the Action of Muscarin upon the Heart, and on the Electrical Changes in the non‐beating Cardiac Muscle brought about by Stimulation of the Inhibitory and Augmentor Nerves

1887 • 51 citations

Mytolon and related compounds as antagonists of acetylcholine on the heart of Venus mercenaria.

1952 • 51 citations

The potentiation of ganglionic transmission by histamine and pilocarpine

1955 • 51 citations

The reaction of chymotrypsin and diisopropylphosphofluoridate I. Isolation and analysis of Diisopropylphosphoryl-peptides

1958 • 51 citations

The antagonisms of atropine to the EEG effects of adrenergic drugs.

1959 • 51 citations

RELATION BETWEEN ELECTRICAL CHANGES DURING NERVE ACTIVITY AND CONCENTRATION OF CHOLINE ESTERASE

1941 • 51 citations

Cholinergic Innervation of the Digital Arteriovenous Anastomoses of Human Skin. A Histochemical Localization of Cholinesterase

1956 • 51 citations

ACTIONS OF DRUGS ON SINGLE NEURONES IN THE SPINAL CORD AND THALAMUS

1965 • 50 citations

Physiological Changes in Sympathetic Ganglia Infected With Pseudorabies Virus

1955 • 50 citations

Acetylcholinesterase Regeneration in Peripheral Nerve after Irreversible Inactivation

1960 • 50 citations

[Alpha waves studied from the point of view of Pavlovian cerebral physiology].

1955 • 50 citations

ANTIDROMIC ACTIVITY IN MOTOR NERVES AND ITS RELATION TO A GENERATOR EVENT IN NERVE TERMINALS

1961 • 50 citations

Pharmacologic evidence for the existence of a presynaptic event in neuromuscular transmission.

1959 • 49 citations

Paralytic and related effects of certain organic phosphorus compounds.

1956 • 49 citations

TRANSMISSION FAILURE IN SYMPATHETIC NERVES PRODUCED BY HEMICHOLINIUM

1960 • 49 citations

THE EFFECT OF MUSCARINE ON PERFUSED SUPERIOR CERVICAL GANGLIA OF CATS

1956 • 49 citations

Enzymes and drug action

1963 • 49 citations

The Synthetic and Catabolic Enzyme Systems for Acetylcholine and Serotonin in Several Discrete Areas of the Developing Rabbit Brain

1964 • 49 citations

Reliability and regional specificity of cerebral effects of environmental complexity and training.

1964 • 48 citations

Block of conduction by acetylcholine and d-tubocurarine after treatment of squid axon with cottonmouth moccasin venom.

1962 • 48 citations

Affinity of benzoquinonium and ambenonium derivatives for the acetylcholine receptor, tested on the electroplax, and for acetylcholinesterase in solution

1965 • 48 citations

Oximes Antagonistic to Inhibitors of Cholinesterase

1964 • 48 citations

THE INTERACTION BETWEEN EDROPHONIUM (TENSILON) AND ACETYLCHOLINE AT THE MOTOR END‐PLATE

1957 • 48 citations

Pacemaker potentials. The excitation of isolated rabbit auricles by acetylcholine at low temperatures

1956 • 48 citations

The influence of atropine and scopolamine on the central effects of DFP.

1948 • 48 citations

Reactivation of phosphorylated acetocholinesterases by pyridinium aldoximes and related compounds

1960 • 48 citations

Effect of HC-3 on acetylcholine turnover.

1961 • 48 citations

The administration of di-isopropyl fluorophosphate (DFP) to man; effect on the central nervous system with special reference to the electrical activity of the brain.

1947 • 47 citations

THE "EFFERENT COCHLEAR AND VESTIBULAR SYSTEM" IN <i>LEPUS CUNICULUS </i>L.

1965 • 47 citations

THE ROLE OF CHOLINESTERASE AT THE MYONEURAL JUNCTION

1953 • 47 citations

ACTION OF DRUGS ON THE CHOLINE ESTERASE OF THE BRAIN

1936 • 47 citations

Effects of Morphine, Nembutal, Ether, and Eserine on Two-Neuron and Multineuron Reflexes in the Cat

1945 • 47 citations

A Pharmacological Approach to the Brain from its Inner and Outer Surface.

1963 • 47 citations

The suppression by anti‐esterases of increased capillary permeability in acute inflammation

1960 • 46 citations

Non-nicotinic ganglion-stimulating substances.

1959 • 45 citations

Protection by Oximes of bis-Pyridinium Ions against Lethal Diisopropyl Phosphonofluoridate Poisoning

1958 • 45 citations

Synthesis and pharmacology of dimethylamido-ethoxy-phosphoryl cyanide (tabun) together with a description of some allied anticholinesterase compounds containing the N-P bond.

1951 • 45 citations

ANTAGONISM OF ACETYLCHOLINE BY ADRENALINE ANTAGONISTS

1963 • 45 citations

Investigation on the Acetylcholinesterase Activity of Erythrocytes, Platelets and Plasma in Different Animal Species

1953 • 45 citations

Studies in neuromuscular function. II. Effects of nerve stimulation in normal subjects and in patients with myasthenia gravis.

1956 • 45 citations

STIMULATION OF ISOLATED RABBIT AURICLES BY SUBSTANCES WHICH STIMULATE GANGLIA

1953 • 45 citations

Occurrence of a Porphyrin Pigment in Streptomycetes

1962 • 45 citations

Recherches Sur La Physiologie et la Pharmacologie Du Système Nerveux Autonome: XI.—Essai D'Identification Du Médiateur Cihimique Libéré Dans La Membrane Nictitante Du Chat Par L'Excitation Sympathique

1935 • 44 citations

Metabolism of Systox in the White Mouse and American Cockroach12

1955 • 44 citations

The role of the sino-aortic receptors in the action of adrenaline, nor-adrenaline and acetylcholine on the cerebral cortex

1956 • 44 citations

Pharmacological studies of recurrent cortical inhibition and facilitation

1965 • 44 citations

Central action of anticholinesterases

1939 • 44 citations

Observations on Pharmacology of the Anticholinesterases Sarin and Tabun

1954 • 44 citations

The Tonographic Effects of Echothiophate (Phospholine) Iodide*

1959 • 43 citations

Mechanisms Related to Enzyme Catalysis

1962 • 43 citations

MECHANISM OF NERVE CONDUCTION BLOCK PRODUCED BY ANTICHOLINESTERASES

1947 • 43 citations

THE ORIGIN OF THE ACETYLCHOLINE RELEASED SPONTANEOUSLY FROM THE GUINEA‐PIG ISOLATED ILEUM

1963 • 42 citations

The distribution of cholinesterase in the adrenal glands of the rat, cat and rabbit

1958 • 42 citations

Action of fluoride on cholinesterase—II

1965 • 42 citations

Ueber die gegenseitigen Beziehungen zwischen Curare und Physostigmin

1901 • 41 citations

Isolated nuclei from cells of the cerebral cortex. Preparation and enzyme content

1951 • 41 citations

LOCAL CHOLINERGIC-ADRENERGIC INTERACTION: MECHANISM FOR THE BIPHASIC CHRONOTROPIC RESPONSE TO NERVE STIMULATION.

1963 • 41 citations

The action of acetylcholine on cells in cat cerebellar cortex

1964 • 41 citations

Quantitative Determination of Cholinesterase in Individual Spinal Ganglion Cells

1959 • 40 citations

TREATMENT OF ANTICHOLINESTERASE INTOXICATION WITH OXIMES

1958 • 40 citations

DEATH DUE TO PARATHION, AN ANTICHOLINESTERASE INSECTICIDE

1949 • 40 citations

The release of acetylcholine from the denervated rat diaphragm

1964 • 40 citations

Actions on Insects and Other Invertebrates

1963 • 40 citations

Neuromuscular Pharmacology: Drugs and Muscle Spindles

1963 • 40 citations

THE ANTAGONISM BETWEEN CURARINE AND PROSTIGMIN AND ITS RELATION TO THE MYASTHENIA PROBLEM

1936 • 40 citations

The effect of anti‐cholinesterases injected into the supraoptic nuclei of chloralosed dogs on the release of the oxytocic factor of the posterior pituitary

1956 • 39 citations

In vivo reactivation by pam of brain cholinesterase inhibited by paraoxon

1960 • 39 citations

Electron microscopic localization of cholinesterases in a sympathetic ganglion by a gold-thiolacetic acid method

1965 • 39 citations

DEP: SITE OF INJECTION AND VARIATION IN RESPONSE

1949 • 39 citations

Cholinesterases of human erythrocytes and plasma and their inhibition by antimalarial drugs.

1948 • 39 citations

Acetylcholine content of the rabbit plantaris muscle after denervation

1962 • 39 citations

Augmentation of evoked cortical potentials by topical application of prostigmine and acetylcholine after atropinization of cortex

1954 • 39 citations

Metabolism of Organophosphorus Anticholinesterase Agents

1963 • 39 citations

�ber den Einflu� von Eserin, Tetra�thylpyrophosphat (TEPP) und Neostigmin auf den Blutdruck und die pressorischen Carotissinusreflexe der Ratte

1956 • 39 citations

The release of substances like acetylcholine and adrenaline by the isolated rabbit heart

1956 • 39 citations

SOME STUDIES OF ENZYMATIC EFFECTS OF RABBIT SERUM

1954 • 39 citations

Sensitivity of cortical neurones to acetylcholine

1961 • 39 citations

Anticholinesterase drugs.

1949 • 39 citations

Cholinergic Neurons in Vertebrates

1961 • 38 citations

Reversible conduction block produced by lipid-insoluble quaternary ammonium ions in cetyltrimethylammonium bromide-treated nerves

1959 • 38 citations

Toxicology of herbicides.

1962 • 38 citations

MECHANISM OF INHIBITION OF PHOSPHATASE ACTIVITY BY GLYCINE

1946 • 38 citations

Effect of Sarin on Dark Adaptation in Man: Threshold Changes

1957 • 38 citations

Mode of action of an inhibitor of acetylcholine synthesis

1958 • 38 citations

Studies on the Histogenesis of Blood Platelets

1956 • 38 citations

Über das Schicksal des Acetylcholins im Blute

1928 • 38 citations

Effect of Sarin on Dark Adaptation in Man: Mechanism of Action

1957 • 38 citations

The incorporation of 32P into the nucleotides of ribonucleic acid in pancreas slices during enzyme synthesis and secretion

1954 • 37 citations

The chemical structure of the reactive group of esterases

1955 • 37 citations

The formation of an acetylcholine‐like substance by the isolated rabbit heart

1954 • 37 citations

The actions of several ganglion blocking agents on the postganglionic discharge induced by diisopropyl phosphorofluoridate (DFP) in sympathetic ganglia.

1962 • 37 citations

Reactions of avian muscle to acetylcholine and eserine

1938 • 37 citations

On the excitant effect of acetylcholine on structures in the preganglionic trunk of the cervical sympathetic: with a note on the anatomical complexities of the region

1960 • 37 citations

The action of 3-hydroxyphenyldimethylethyl-ammonium (tensilon) on neuromuscular transmission in the frog.

1954 • 37 citations

A cytological and histochemical study of the carotid body of the cat

1957 • 36 citations

Vegetative Funktionen und Zwischenhirn

1948 • 36 citations

THE MECHANISM OF ANTICURARE ACTION OF CERTAIN NEOSTIGMINE ANALOGUES

1952 • 36 citations

THE INHIBITION OF PURIFIED, HUMAN PLASMA CHOLINESTERASE WITH DIISOPROPYL FLUOROPHOSPHATE

1952 • 36 citations

Cholinesterases in Serum as Demonstrated by Starch Gel Electrophoresis.

1961 • 35 citations

Electron Microscope and Chemical Study of Binding Sites of Brain Biogenic Amines

1964 • 35 citations

Use of oximes in the treatment of intoxication by anticholinesterase compounds in patients with myasthenia gravis

1958 • 35 citations

A Study of the Action of Nembutal on Diencephalic and Mesencephalic Unit Activity

1956 • 35 citations

Ein Vorlesungsversuch zur Demonstration der erregbarkeitssteigernden Wirkung des Physostigmins

1917 • 35 citations

ACTION OF INTRATHECALLY INJECTED PROSTIGMINE, ACETYLCHOLINE, AND ESERINE ON THE CENTRAL NERVOUS SYSTEM IN MAN

1942 • 35 citations

Acetylcholine and Nerve Activity

1964 • 34 citations

THE ACTION OF ACETYLCHOLINE ON THE RABBIT AURICLE*

1950 • 34 citations

Oxime Therapy in Poisoning by Six Organo-phosphorus Insecticides in the Rat

1959 • 34 citations

On The Physiological Significance of Choline Esterase.

1940 • 34 citations

The mechanisms of motor end‐plate depolarization due to a cholinesterase‐inhibiting drug

1954 • 34 citations

Neurotoxicity of Organophosphorus Compounds

1963 • 34 citations

Ontogenesis of Cholinesterases

1963 • 34 citations

Molecular complementarity and antidotes for alkylphosphate poisoning.

1959 • 34 citations

Some observations on salivary secretion

1935 • 34 citations

The Significance of Enzyme Studies on Isolated Cell Nuclei

1954 • 33 citations

Contribution to the study of the mechanism of action of cholinesterase inhibitors.

1951 • 33 citations

The effects of some drugs on the repetitive discharges produced in nerve and muscle by anticholinesterases

1963 • 33 citations

Concentration of choline acetylase in conducting tissue

1956 • 33 citations

The structure of the autonomic interneuronal synapse

1964 • 33 citations

Nature of the Acetyl Cholinesterase Surface. III. Enzymatic Response to cis-trans Isomers in the Cyclohexane Series as Mapping Agents1,2

1955 • 33 citations

Die Regeneration der subneuralen Apparate der motorischen Endplatten

1958 • 33 citations

STUDIES IN MYASTHENIA GRAVIS

1953 • 32 citations

Central cholinergic blockade of the conditioned avoidance response in rats

1964 • 32 citations

REACTION OF α-CHYMOTRYPSIN WITH ANALOGUES OF DIISOPROPYL FLUOROPHOSPHATE

1951 • 32 citations

The effects of some possible neurohumoral agents on spinal cord reflexes.

1959 • 32 citations

New evidence for the role of acetylcholine in conduction

1960 • 32 citations

Mode of action of antagonists to curare.

1952 • 32 citations

Functions of Autonomic Transmitters

1957 • 32 citations

STUDIES ON PHYSOSTIGMINE AND RELATED SUBSTANCES IV. CHEMICAL STUDIES ON PHYSOSTIGMINE BREAKDOWN PRODUCTS AND RELATED EPINEPHRINE DERIVATIVES

1943 • 32 citations

PSYCHOPHARMACOLOGICAL EFFECTS OF REVERSIBLE CHOLINESTERASE INHIBITION INDUCED BY N-METHYL 3-ISOPROPYL PHENYL CARBAMATE (COMPOUND 10854).

1963 • 32 citations

THE ROLE OF ACETYLCHOLINE IN BRAIN METABOLISM AND FUNCTION

1957 • 31 citations

Der Nachweis des Vagusstoffes beim Säugetier

1926 • 31 citations

Enzymic Properties of Cholinesterases in Subcellular Fractions From Rat Brain

1960 • 31 citations

The purification and properties of the tyrosine–2-oxoglutarate transaminase of Saccharomyces cerevisiae

1960 • 31 citations

Some Derivatives of 3-Pyridol with Parasympathomimetic Properties1

1951 • 31 citations

Localization of acetylcholine, 5-hydroxytryptamine and noradrenaline within suhcellular particles derived from guinea pig subcortical brain tissue

1963 • 31 citations

Vergiftungen mit esteraseblockierenden Insecticiden aus der Gruppe der organischen Phosphorsäure-Ester (E 605 und Verwandte)

1958 • 31 citations

Stimulation of Motor Nerve Terminals

1961 • 31 citations

The role of acetylcholine in virus‐infected sympathetic ganglia

1957 • 31 citations

Pharmacologic Considerations in a Reevaluation of the Neuromuscular Synapse

1960 • 31 citations

TRANSMISSION OF IMPULSES IN PERIPHERAL NERVES TREATED WITH DI-ISOPROPYL FLUORPHOSPHATE (DFP)

1946 • 31 citations

Acute toxicity and anticholinesterase action of O,O-dimethyl O-[4-(methylthio)-m-tolyl] phosphorothioate (DMTP; Baytex) and related compounds

1964 • 30 citations

242. Esters containing phosphorus. Part III. Dialkyl iodophosphonates

1945 • 30 citations

MODIFICATION OF GANGLIONIC RESPONSES TO CHOLINOMIMETIC DRUGS FOLLOWING PREGANGLIONIC STIMULATION, ANTICHOLINESTERASE AGENTS AND PILOCARPINE.

1964 • 30 citations

EFFECT OF DENERVATION ON ENZYMES IN IRIS AND BLOOD VESSELS

1954 • 30 citations

Effects of close arterial injections of acetylcholine on the activity of the cervical spinal cord of the cat

1953 • 30 citations

Mechanism of Insecticide Action, Preparation, Purfication, Isomerization, and Biological Properties of Octamethylpyrophosphoramide N-Oxide

1955 • 30 citations

Effects of certain metabolically active drugs and oximes on tri-o-cresyl phosphate toxicity

1965 • 29 citations

The ionic requirements for the action of acetylcholine on mammalian non‐myelinated fibres

1963 • 29 citations

Potentiation Between Cholinesterase Inhibitors.

1958 • 29 citations

A pharmacological study on the Renshaw cell.

1960 • 29 citations

CHOLINOCEPTIVE SITES IN DENERVATED SYMPATHETIC GANGLIA.

1963 • 29 citations

SOME SELECTIVE INHIBITORS OF TRUE CHOLINESTERASE*

1954 • 29 citations

TUBOCURARINE ANTAGONISM AND INHIBITION OF CHOLINESTERASES

1949 • 29 citations

Anticholinesterases in the heart‐lung preparation

1954 • 29 citations

Neuro‐muscular conduction in the fowl

1938 • 29 citations

Cholinesterase in Muscles: A Histochemical and Microgasornetric Study

1960 • 29 citations

EFFECT OF PARASYMPATHETIC DRUGS ON THE CONDITIONED RESPONSE

1947 • 29 citations

A NEW SERIES OF SYNTHETIC CURARE‐LIKE COMPOUNDS

1951 • 29 citations

MODE OF ACTION OF SUCCINYLCHOLINE ON SENSORY ENDINGS OF MAMMALIAN MUSCLE SPINDLES

1961 • 29 citations

CURARIZATION OF DENERVATED MUSCLE

1951 • 29 citations

Pharmacological properties of some neostigmine analogs.

1950 • 28 citations

SYNTHETIC DRUGS INFLUENCING NEUROMUSCULAR ACTIVITY

1951 • 28 citations

Dichlorhydrate de bétahistine versus flunarizineEtude en double aveugle dans les vertiges récurrents avec ou sans syndrome typique de Ménière

1991 • 28 citations

The effect of hemicholinium (HC-3) at various peripheral cholinergic transmitting sites.

1959 • 28 citations

QUINIDINE AND ANTICHOLINESTERASES ON RABBIT AURICLES

1954 • 28 citations

Excitation of Cerebellar Neurones by Acetylcholine

1963 • 28 citations

The relationship between cholinesterase inhibition and ganglionic transmission.

1952 • 28 citations

Some Behavioral Effects of Atropine and Methyl Atropine

1962 • 28 citations

The effects of anti‐cholinesterases upon peripheral vascular resistance in the dog

1956 • 28 citations

The chronic toxicity of di-isopropyl fluorophosphate (DFP) in dogs, monkeys and rats.

1946 • 27 citations

Differential effects of a quaternary cholinesterase inhibitor, phospholine, and its tertiary analogue, compound 217-AO, on central control of respiration and on neuromuscular transmission: the antagonism by 217-AO of the respiratory arrest caused by morphine.

1958 • 27 citations

Effects of atropine, prostigmine and acetylcholine on evoked cortical potentials

1955 • 27 citations

Actions at the Neuromuscular Junction

1963 • 27 citations

Distribution and excretion of pyridine-2-aldoxime methiodide (PAM); atropine and PAM in sarin poisoning

1963 • 27 citations

Synaptic Transmission

1963 • 27 citations

Action of Acetylcholine on Cochlear Responses

1965 • 27 citations

Comparison of Physostigmine and Amphetamine in Antagonizing the EEG Effects of GNS Depressants.

1959 • 27 citations

THE CHOLINERGIC COMPONENT IN THE SYMPATHETIC INNERVATION TO THE SPLEEN.

1965 • 27 citations

Die Wiederherstellung der Cholinesteraseaktivit�t bei der Alkylphosphat-Vergiftung eurch ein spezifisches Antidot

1957 • 27 citations

The enzymatic hydrolysis of p-nitrophenyl ethyl phosphonates by mammalian plasmas

1964 • 27 citations

Pharmacological Antagonists of the Anticholinesterase Agents

1963 • 26 citations

Orthodromic activation of single ganglion cells

1963 • 26 citations

The preparation of a soluble acetylcholinesterase from brain

1964 • 26 citations

Esterases of rat-liver cell fractions

1963 • 26 citations

Some properties of isozymes of brain acetylcholinesterase

1963 • 26 citations

The action of acetylcholine on the nictitating membrane of the spinal cat.

1962 • 26 citations

L'Effet De La Section Des Fibres Préganglionnaires Sur La Teneur En Acétylgholine Du Ganglion Sympathique

1938 • 26 citations

Microphysiology of the neuromuscular junction; a physiological quantum of action at the myoeneural junction.

1958 • 26 citations

On the Calabar Bean as a New Agent in Ophthalmic Medicine

1863 • 26 citations

A pharmacological investigation of 2,5-bis-(3-diethylaminopropylamino) benzoquinone-bis-benzylchloride (WIN 2747): a new curarimimetic drug.

1950 • 26 citations

The Transmission of Nerve Impulses at Neuroeffector Junctions and Peripheral Synapses

1951 • 26 citations

Über die Ester der pyrophosphorigen, der Unterphosphor‐ und der Pyrophosphorsäure. I. Mitteilung. Die Äthylester, ihre Darstellung und ihre Eigenschaften

1931 • 25 citations

Facilitation of ganglionic transmission following inhibition of cholinesterase by DFP.

1954 • 25 citations

A pharmacologic comparison of hexaethyl tetraphosphate and teraethyl pyrophosphate with physostigmine neostigmine and diisopropyl fluorophosphate.

1949 • 25 citations

Narkosepotenzierende und analgetische Wirkung von 1,4-Dipyrrolidino-2-butin

1958 • 25 citations

Chemical Reactions of Nerve Gases in Neutral Solution. I. Reactions with Hydroxylamine1

1956 • 25 citations

Interaction of Acetylcholine, Calcium and Depolarization in the Contraction of Smooth Muscle

1961 • 25 citations

ESERINE, ACETYLCHOLINE, ATROPINE AND NERVOUS INTEGRATION

1943 • 25 citations

The Effect of Sodium Fluoride on Sarin Inhibited Blood Cholinesterases.

1964 • 25 citations

DIALKYLFLUOROPHOSPHATASE OF KIDNEY

1953 • 25 citations

Toxicological Evaluation of the Anticholinesterase Agents

1963 • 25 citations

Adjunctive value of oral prophylaxis with the oximes 2-PAM lactate and 2-PAM methanesulfonate to therapeutic administration of atropine in dogs poisoned by inhaled Sarin vapor.

1962 • 25 citations

Evidence supporting cholinergic transmission at the lateral geniculate body of the cat

1963 • 24 citations

Lack of Evidence for a Cholinergic Mechanism in Sympathetic Transmission

1961 • 24 citations

The nature of the innervation of the smooth muscle, Harderian gland and blood vessels of the cat's nictitating membrane

1962 • 24 citations

Effects of age of training on cholinesterase activity in the brain of maze-bright rats.

1962 • 24 citations

EFFECTS OF DRUGS WHICH DEPRESS THE PERIPHERAL NERVOUS SYSTEM ON THE RETICULAR ACTIVATING SYSTEM OF THE CAT

1958 • 24 citations

INHIBITION OF BRAIN DEHYDROGENASES BY ‘ANTICHOLINESTERASES’

1949 • 24 citations

Action of condensed alkyl phosphates on the nerve‐muscle preparation and the central nervous system of the cat

1949 • 24 citations

Visual Effects Accompanying TEPPInduced Miosis

1956 • 24 citations

Acetylcholine: a Central Transmitter?

1962 • 24 citations

Effects of ethyl p-nitrophenyl thionobenzene phosphonate (EPN) on the toxicity of isopropyl methyl phosphonofluoridate (GB).

1963 • 24 citations

Chromatography of Human Serum Cholinesterase.

1956 • 24 citations

THE RELEASE OF ACETYLCHOLINE FROM A SYMPATHETIC GANGLION BY CARBACHOL: RELATIONSHIP TO THE FUNCTIONAL SIGNIFICANCE OF THE LOCALIZATION OF ACETYLCHOLINESTERASE

1963 • 24 citations

The pharmacological reactivity of presynaptic nerve terminals in a sympathetic ganglion.

1959 • 24 citations

�ber die Ateml�hmung durch Parathion oder Paraoxon und ihre antagonistische Beeinflu�barkeit

1958 • 23 citations

Antagonism between a bis-quaternary oxamide, Win 8078, and depolarizing and competitive blocking agents.

1957 • 23 citations

THE SIZE AND SHAPE OF THE RADIOSENSITIVE ACETYLCHOLINESTERASE UNIT

1956 • 23 citations

Effects of Drugs on the Central Nervous System

1964 • 23 citations

Einige Bemerkungen zur Struktur der peripheren Endausbreitung vegetativer Nerven

1957 • 23 citations

Further observations on the action of acetylcholine, prostigmine and related substances on the knee jerk

1937 • 23 citations

THE PART PLAYED BY INHIBITION OF CHOLINESTERASES OF THE CNS IN PRODUCING PARALYSIS IN CHICKENS

1954 • 23 citations

PROTECTION AGAINST THE TOXICITY OF CHOLINESTERASE INHIBITORS BY ACETYLCHOLINE ANTAGONISTS

1954 • 23 citations

Effect of Tertiary and Quaternary Atropine Salts on Absolute Scotopic Threshold Changes Produced by an Anticholinesterase (Sarin)

1958 • 23 citations

THE RELATIVE ACTIVITY OF PROSTIGMINE HOMOLOGUES AND OTHER SUBSTANCES AS ANTAGONISTS TO TUBOCURARINE

1947 • 23 citations

DEPOLARIZING ACTION OF NEOSTIGMINE AT AN AUTONOMIC GANGLION

1962 • 23 citations

WIN 8077 IN TREATMENT OF MYASTHENIA GRAVIS

1955 • 23 citations

CYTOCHEMISTRY OF NEURONES AND NEUROGLIA

1957 • 23 citations

Protective Effect of Phenothiazine Derivatives against Poisoning by the Irreversible Cholinestcrase Inhibitor Dimethylamido‐ethoxyphosphoryl Cyanide (Tabun).

1953 • 22 citations

Central Cholinolytic Action of Chlorpromazine

1962 • 22 citations

OXIME REACTIVATION STUDIES OF INHIBITED TRUE AND PSEUDO CHOLINESTERASE

1959 • 22 citations

Acetylcholinesterase in the Conductive Tissue of the Heart

1953 • 22 citations

Bis-ammonium Salts. Derivatives of Fluorene, Carbazole and Phenothiazine

1954 • 22 citations

Studies on the mechanism of action of DFP and TEPP.

1954 • 22 citations

Acceleration of Plasma Cholinesterase Activity by Quaternary Ammonium Salts

1958 • 22 citations

Cholinesterases and the Mode of Action of Some Anticholinesterases

1954 • 22 citations

Actions on Axons, and Evidence for the Role of Acetylcholine in Axonal Conduction

1963 • 22 citations

SOME NEW ASPECTS OF MORPHINE ACTION EFFECT ON INTESTINE AND BLOOD PRESSURE; TOXICITY STUDIES

1940 • 22 citations

THE EFFECT OF ESERINE ON THE RESPONSE OF THE VAS DEFERENS TO HYPOGASTRIC NERVE STIMULATION

1963 • 22 citations

A neuropharmacological study of gamma-aminobutyryl-choline, gamma-aminobutyric acid, physostigmine and atropine.

1963 • 22 citations

Beitrag zur Frage der Inkret-(Hormon-)Wirkung des Cholins auf die motorischen Funktionen des Verdauungskanales

1925 • 22 citations

Studies on the percutaneous absorption of sarin and two allied organophosphorus cholinesterase inhibitors.

1958 • 22 citations

Intra-Axonal Injection of Biologically Active Materials

1958 • 22 citations

Evaluation and Use of Oximes in Ophthalmology*

1958 • 21 citations

Localisation intracellulaire des cholinestérases I. Foie de quelques mammifères

1955 • 21 citations

Sources of error in relating electrical and acetylcholinesterase activity

1962 • 21 citations

Enzymic Hydrolysis of Organophosphorus Compounds. II. Analysis of Reaction Products in Experiments with Tabun and Some Properties of Blood Plasma Tabunase.

1954 • 21 citations

Excitation and inhibition of cholinoceptive brain structures and its relationship to pharmacological induced behaviour changes

1963 • 21 citations

THE INFLUENCE OF HEMICHOLINIUM NO. 3 AND VAGAL STIMULATION ON ACETYLCHOLINE CONTENT OF RABBIT ATRIA.

1963 • 21 citations

Averaged evoked potentials and cholinergic synapses in the somatosensory cortex of the cat

1965 • 21 citations

Cholinesterase activity in the auricles of the rabbit's heart and their sensitivity to eserine

1954 • 21 citations

DIALKYLFLUOROPHOSPHATASE OF KIDNEY

1956 • 21 citations

A COMPARISON BETWEEN THE EFFECTS OF EDROPHONIUM AND CHOLINE IN THE SKELETAL MUSCLES OF THE CAT

1959 • 20 citations

A COMPARISON OF THE RESPONSES OF THE TENUISSIMUS MUSCLE TO NEUROMUSCULAR BLOCKING DRUGS IN VIVO AND IN VITRO

1962 • 20 citations

Comparison of simultaneously recorded electrical and mechanical activity in myasthenia gravis patients and in partially curarized normal humans

1955 • 20 citations

Central and Synaptic Transmission (Pharmacological Aspects)

1956 • 20 citations

THE ADRENERGIC MECHANISM IN THE NICTITATING MEMBRANE

1963 • 20 citations

Brain Acetylcholinesterase Activities in Rabbits Exhibiting Three Behavioral Patterns Following the Intracarotid Injection of Di-Isopropyl Fluorophosphate

1954 • 20 citations

Evaluation of curarizing drugs in man. V. Antagonism to curarizing effects of d-tubocurarine by neostigmine, m-hydroxy phenyltrimethylammonium and m-hydroxy phenylethyldimethylammonium.

1950 • 20 citations

Concentration of morphine in blood and brain after intravenous injection of morphine in non-tolerant, tolerant and neostigmine-treated rats.

1956 • 20 citations

Effects of early handling and light stimulation on the acetylcholinesterase activity of the developing rat brain

1965 • 20 citations

The mechanism of action of anticholinesterases. II. The effect of diisopropylfluorophosphonate (DFP) on the isolated rat phrenic nervediaphragm preparation. A. Irreversible effects.

1956 • 20 citations

Effect of Acetylcholine on the Electrical Activity of Somatic Nerves of the Lobster

1962 • 20 citations

The Pathology of Experimental Cholinesterase-Inhibitor Poisoning.

1957 • 19 citations

ACETYLCHOLINE RELEASE AT THE NEUROMUSCULAR JUNCTION.

1963 • 19 citations

Acetylcholine activity in the sciatic nerve

1963 • 19 citations

A New Anticholinesterase Oxamide

1954 • 19 citations

THE EFFECTS OF INTRACISTERNAL SARIN AND PYRIDINE‐2‐ALDOXIME METHYL METHANESULPHONATE IN ANAESTHETIZED DOGS

1960 • 19 citations

THE PHYSIOLOGY OF SWEATING*

1953 • 19 citations

THE ANTAGONISM OF MUSCLE RELAXANTS AMBENONIUM AND METHOXYAMBENONIUM IN THE CAT

1960 • 19 citations

A REVIEW OF COMPARATIVE BEHAVIORAL PHARMACOLOGY

1957 • 19 citations

PHARMACOLOGICAL ACTIONS OF TETRAETHYLPYROPHOSPHATE AND HEXAETHYLTETRAPHOSPHATE

1949 • 19 citations

THE MECHANISMS FOR CHYMOTRYPSIN

1961 • 19 citations

Dual Action of Nicotine on the Sympathetic Ganglion of the Cat.

1953 • 19 citations

New Perspectives in Biology

1963 • 19 citations

The effect of the intravenous injection of DFP and atropine on the level of free acetylcholine in the cerebral cortex of the rabbit.

1954 • 19 citations

THE RELEASE OF ACETYLCHOLINE FROM A SYMPATHETIC GANGLION BY CARBACHOL: RELATIONSHIP TO THE FUNCTIONAL SIGNIFICANCE OF THE LOCALIZATION OF ACETYLCHOLINESTERASE

1963 • 19 citations

Hexafluorenium: its anticholinesterase and neuromuscular activity.

1960 • 19 citations

Antidotes and potentiating agents for phospholine iodide.

1960 • 19 citations

INTERACTION OF NICOTINE AND ESERINE, EPHEDRINE, ATROPINE, HEXAMETHONIUM, AND ADRENALINE IN ISOLATED GUINEA‐PIG AURICLES

1954 • 19 citations

Extension of tranquilizer action by anticholinesterases

1964 • 19 citations

A DEPRESSANT EFFECT OF ACETYLCHOLINE ON THE IDIO‐VENTRICULAR PACEMAKER OF THE ISOLATED PERFUSED RABBIT HEART

1958 • 19 citations

Trial by ordeal

1945 • 18 citations

The relationship between cholinesterase inhibition and function in a neuroeffector system.

1949 • 18 citations

Physiological Effects of Alkyl Polyphosphates

1947 • 18 citations

Curare and Curare-like Agents.

1959 • 18 citations

The mechanism of action of anti-cholinesterases.

1955 • 18 citations

DIALKYLFLUOROPHOSPHATASE OF KIDNEY

1954 • 18 citations

Reactivation of phosphorylated acetocholinesterase by pyridine-2-aldoxime methiodide

1957 • 18 citations

Protection of true cholinesterase against diisopropyl fluorophosphonate by butyrycholine

1950 • 18 citations

Experiments with Methyl-fluoro-phosphorylcholine-inhibited Cholinesterase.

1958 • 18 citations

Pharmacology of the Autonomic Nervous System

1963 • 18 citations

Contributions of Medical Research in Chemical Warfare to Medicine

1945 • 18 citations

THE USE OF MYTOLON CHLORIDE IN ANESTHESIOLOGY

1951 • 17 citations

THE RELEASE OF ACETYLCHOLINE BY SYMPATHETIC NERVE STIMULATION AT DIFFERENT FREQUENCIES

1963 • 17 citations

The action of acetylcholine, eserine and other substances on some motor responses of the central nervous system

1941 • 17 citations

Electromyographic changes in myasthenia gravis

1955 • 17 citations

The effects of psychotropic drugs on the cholinergic and adrenergic system

1964 • 17 citations

The acute toxicity and anticholinesterase action of O,O-dimethyl S-ethyl-2-sulfinylethyl phosphorothioate (Meta-Systox R®) and related compounds

1962 • 17 citations

Hydrolysis of Carboxylic Acid Esters of Thiocholine and its Analogues. 1. Acid Hydrolysis.

1958 • 17 citations

Actions at the Central Nervous System

1963 • 17 citations

The muscularis mucosae of the oesophagus of the cat, rabbit and rat

1955 • 17 citations

Electrophysiological analysis of the neuroleptic and antidepressant actions of psychotropic drugs in rabbits

1964 • 17 citations

DISTRIBUTION OF CHOLINESTERASES IN THE MAMMALIAN PANCREAS

1955 • 17 citations

On the Metabolism of Acetylcholine Precursor in Isolated Hearts

1945 • 17 citations

Modifying Actions of Procaine on the Myoneural Blocking Actions of Succinylcholine, Decamethonium and d-Tubocurarine in Dogs and Cats

1953 • 17 citations

The interaction between cholinesterases and a series of local anesthetics.

1956 • 17 citations

Neurohumors in the brain.

1959 • 17 citations

Effects of “Biochemical Lesions” of behavior

1959 • 17 citations

ABNORMAL END-PLATES IN MYASTHENIC MUSCLE

1958 • 17 citations

ELECTROLYTE CHANGES IN SUBMAXILLARY GLANDS DURING STIMULATION

1941 • 17 citations

Metabolic Diseases of Muscle

1963 • 17 citations

Effects of Chronic Dieldrin Ingestion on the Muscular Efficiency of Rats

1960 • 17 citations

Acetylcholine Inactivation and Acetylcholine Sensitivity in Denervated Salivary Glands

1955 • 17 citations

WIN 8077 in the treatment of sixty myasthenia gravis patients

1955 • 17 citations

Endplate effects and antagonism to d-tubocurarine and decamethonium of tetraethylammonium and of methoxyambem (WIN 8078).

1961 • 16 citations

The treatment of di-isopropyl fluorophosphate (DFP) poisoning in rabbits.

1946 • 16 citations

Autonomic postganglionic innervation of the nictitating membrane of the cat.

1956 • 16 citations

GENERAL SYSTEMIC ACTIONS OF DI-ISOPROPYL FLUOROPHOSPHATE (DFP) IN CATS

1946 • 16 citations

ROLE OF ACETYLCHOLINE IN THE ACTIVITY OF SENSORI-MOTOR AND SUPPRESSOR AREAS OF THE CORTEX

1948 • 16 citations

Preliminary studies on the "reversed carboxyl" analogue of acetylcholine.

1950 • 16 citations

THE EFFECTS OF ANTICHOLINESTERASES ON HUMORAL TRANSMISSION IN THE SUBMAXILLARY GLAND

1954 • 16 citations

Pharmacogenetics; heredity and the response to drugs.

1963 • 16 citations

Restoration by a specific chemical reaction of “irreversibly” blocked axonal electrical activity

1964 • 16 citations

THE EFFECTS OF BARIUM AND OTHER INORGANIC CATIONS ON SYMPATHETIC GANGLIA.

1964 • 16 citations

Studies in neuromuscular function. VI. Effects of anticholinesterase compounds, d-tubocurarine, and decamethonium in patients with myasthenia gravis.

1956 • 16 citations

THE POSSIBILITY OF THE DUAL NATURE OF SYMPATHETIC GANGLION CELLS III

1951 • 15 citations

Effect of Tetraethyl Pyrophosphate on Sympathetic Ganglionic Activity

1947 • 15 citations

Parathion Poisoning and Its Treatment

1965 • 15 citations

Bemerkungen zur Kinetik und Substratspezifit�t der Cholinesterasen

1952 • 15 citations

�ber die Wirkung von Esteraseblockern (E 605, Eserin und Prostigmin) auf das Atemzentrum von Katze und Hund

1955 • 15 citations

Elektrophysiologischer Nachweis spontaner Freisetzung von Acetylcholin im Vorhof des Herzens

1960 • 15 citations

The thermal inactivation of acetylcholinesterase

1963 • 15 citations

FIBRILLATION OF MUSCLE FIBERS PRODUCED BY AMMONIUM IONS AND ITS RELATION TO THE SPONTANEOUS ACTIVITY AT THE NEUROMUSCULAR JUNCTION

1957 • 15 citations

Mechanism of the positive chronotropic response to nicotine.

1962 • 15 citations

Inhibition of Cholinesterases by 1 : 2 : 4-Triazoles

1955 • 15 citations

THE EFFECTS OF ANTICHOLINESTERASES ON THE BRONCHIOLES AND PULMONARY BLOOD VESSELS IN ISOLATED PERFUSED LUNGS OF THE DOG

1957 • 15 citations

The quantitative evaluation of autonomic drugs on the isolated eye.

1962 • 15 citations

Reversible Block of Axonal Conduction by Curare after Treatment with Cobra Venom and a Detergent

1961 • 15 citations

THE EFFECT OF ESERINE ON SPINAL REFLEXES IN THE DOG

1939 • 15 citations

A study of presynaptic slow potentials in virus‐infected sympathetic ganglia of the rat

1960 • 15 citations

The effect of introduction of some drugs into the cerebral ventricles on the electrical activity of the brain of cats

1954 • 14 citations

SIMILARITIES IN THE GANGLIONIC ACTIONS OF CALCIUM IONS AND ATROPINE.

1964 • 14 citations

THE REACTIONS OF RABBITS TO POISONING BY p‐NITROPHENYLDIETHYLPHOSPHATE (E600)

1953 • 14 citations

THE INACTIVATION OF CHOLINESTERASE BY MORPHINE, DILAUDID, CODEINE AND DESOMORPHINE

1943 • 14 citations

Pharmacological properties of methyl-fluoro-phosphorylcholines; two synthetic cholinergic drugs.

1957 • 14 citations

Further elements of structural specificity in potentiation and blockade of excitable tissue preparations by aryl esters of tropine and ψ-tropine. III

1963 • 14 citations

FORCED CIRCLING MOVEMENTS (ADVERSIVE SYNDROME) Correction with Dinenhydrinate ("Dramamine")

1950 • 14 citations

Antidote effect of sodium fluoride in organophosphorus anticholinesterase poisoning

1965 • 14 citations

Effects of “biochemical lesions” on behavior

1958 • 14 citations

An evaluation of the pharmacologic actions of some bis-quaternary salts of basically substituted oxamides (WIN 8077 and analogs).

1955 • 14 citations

Anticholinesterase activities of some bis-quaternary ammonium salts

1959 • 14 citations

EFFECTS OF ESERINE AND ACETYLCHOLINE ON THE RESPIRATORY CENTERS AND HYPOGLOSSAL NUCLEI

1949 • 14 citations

[Analysis of the stimulating and paralyzing effects of alkylphosphates (parathion, paraoxon, systox) on isolated rabbit intestines].

1958 • 14 citations

�ber die Beeinflussung zentral d�mpfender und erregender Morphinwirkungen durch Anticholinergica, Nicotinolytica und Antihistaminica an der Ratte

1961 • 14 citations

AUTONOMIC AND PHARMACOLOGIC CONTROL OF COLONIC ACTIVITY

1954 • 14 citations

On the Problem of the Serine-Histidine Hydrogen Bond in the Active Site of α-Chymotrypsin†

1963 • 14 citations

AMINO ACID AND PROTEIN METABOLISM OF THE BRAIN‐VII1 THE PENETRATION OF CHOLINESTERASE INHIBITORS INTO THE NERVOUS SYSTEM OF THE FROG

1961 • 13 citations

A CORRELATION BETWEEN CHOLINESTERASE INHIBITION AND INCREASE IN MUSCLE TONE IN RABBIT DUODENUM

1955 • 13 citations

SOME EFFECTS OF SOMAN ON NEUROMUSCULAR FUNCTION AND ON ACETYLCHOLINESTERASE IN THE RAT

1964 • 13 citations

The responses to ganglionic stimulating and blocking drugs of cell groups within a sympathetic ganglion.

1962 • 13 citations

ALTERATIONS IN MUSCLE TENSION WITHOUT SIMILAR CHANGES IN ELECTRICAL ACTIVITY IN PATIENTS WITH MYASTHENIA GRAVIS 1

1955 • 13 citations

Toxicity of Hydroxamic Acid Analogues; Prophylactic and Therapeutic Efficacy Against Nerve Gas Poisoning in Mice.

1956 • 13 citations

A comparison between the responses of avian and mammalian muscles to substances with facilitate neuromuscular transmission.

1962 • 13 citations

Nervous control of the cat nictitating membrane

1962 • 13 citations

ON THE PHYSOSTIGMINE-LIKE ACTION OF CERTAIN SYNTHETIC URETHANES

1931 • 13 citations

An investigation of the structure-activity correlations within a series of ambenonium analogs.

1958 • 13 citations

The active surface of pseudo-cholinesterase and the possible role of this enzyme in conduction

1953 • 13 citations

Chemical Stimulation of Telencephalon, Diencephalon and Mesencephalon in Unrestrained Animals*†

1960 • 13 citations

Localization of cholinesterases in adult mammalian brain cell cultures

1962 • 13 citations

Inhibition of Cholinesterase by Adrenaline

1948 • 13 citations

STUDIES ON THE SYNERGISM AND ANTAGONISM OF DRUGS I. THE NON-PARASYMPATHETIC ANTAGONISM BETWEEN ATROPINE AND THE MIOTIC ALKALOIDS

1932 • 12 citations

Antagonism of tubocurarine. III. Time course of action of pyridostigmin, neostigmine, and edrophonium in vivo and in vitro.

1957 • 12 citations

Action of intrathecally injected eserine on the spinal cord of the cat

1947 • 12 citations

Effects of Intracerebral Injection of Anticholinesterase Drugs on Behavior in Rats

1958 • 12 citations

The effect of d-tubocuarine on the neuromuscular blocks caused by diisopropylfluorophosphate and acetylcholine.

1956 • 12 citations

A comparative study of some pyridinium oximes as reactivators of phosphorylated acetylcholinesterase and as antidotes in sarin poisoning

1963 • 12 citations

Inhibition of human cholinesterases by narcotics, analgesics and their antagonists.

1959 • 12 citations

The antagonism between curarine and acetylcholine

1936 • 12 citations

Actions of inorganic ions and veratrine on asynchronous postganglionic discharge in sympathetic ganglia treated with diisopropyl phosphorofluoridate (DFP).

1962 • 12 citations

CHOLINESTERASE ACTIVITY OF BLOOD AND MUSCLE IN MYASTHENIA GRAVIS

1951 • 12 citations

The Effect of Choline on the Action of Anticholinesterases.

1956 • 12 citations

Specific and Non-Specific Factors in Psychopharmacology

1963 • 12 citations

THE ADRENERGIC NATURE OF NEUROHUMORAL TRANSMISSION IN THE CAT NICTITATING MEMBRANE FOLLOWING TREATMENT WITH RESERPINE

1962 • 12 citations

Analyse der erregenden und l�hmenden Wirkung von Alkylphosphaten (Parathion, Paraoxon, Systox) am isolierten Kaninchendarm

1958 • 12 citations

BEHAVIORAL EFFECTS OF A CHOLINERGIC STIMULANT IN COMBINATION WITH VARIOUS PSYCHOTHERAPEUTIC AGENTS.

1964 • 12 citations

The use of the developing chick embryo in pharmacologic research.

1955 • 12 citations

Cholinesterase inhibition and the effect of anti-cholinesterases on indirectly evoked single and tetanic muscle contractions in the phrenic nerve-diaphragm preparation from the rat.

1960 • 12 citations

Toxicologic properties and stereochemical configuration in derivatives of the tropanol series

1960 • 11 citations

Stimulation of denervated muscle by DFP and related compounds.

1956 • 11 citations

Effect of tubocurarine on action potentials in normal and denervated skeletal muscle

1964 • 11 citations

Acetylcholine as a pharmacological agent.

1948 • 11 citations

The relation between end‐plate depolarization and the repetitive response elicited in the isolated rat phrenic nerve‐diaphragm preparation by DFP

1958 • 11 citations

A NOTE ON THE DEMYELINATION PRODUCED IN HENS BY DIALKYLFLUORIDATES

1960 • 11 citations

Studies on the inter-relationships of certain cholinergic compounds. III. The reactions between 3-acetoxy phenyltrimethylammonium methylsulfate, 3-hydroxy phenyltrimethylammonium bromide and cholinesterases.

1950 • 11 citations

Correlation between pharmacological responses to benzoylcholine, methacholine and acetylcholine and activity of cholinesterases.

1953 • 11 citations

Beitrag zur Frage der Inkret-(Hormon)-Wirkung des Cholins auf die motorischen Funktionen des Verdauungskanales

1925 • 11 citations

Studies on the pharmacology of tetraethylpyrophosphate.

1955 • 11 citations

Neuromuscular transmission in myasthenia gravis

1955 • 11 citations

The administration of di-isopropyl fluorophosphate to man; the effects on neuromuscular function in normal subjects and in myasthenia gravis.

1947 • 11 citations

Further study of 3-hydroxyphenyldimethylethylammonium (edrophonium) and its closely related analogues with respect to activity at the neuromuscular junction

1959 • 11 citations

THE EFFECTS OF DRUGS ON NERVE ACTIVITY

1946 • 11 citations

Toxicity arising from joint intravenous administration of EPN and malathion to dogs

1962 • 11 citations

Antidotes to poisoning by di-isopropyl fluorophosphate in cats.

1946 • 11 citations

Localisation intracellulaire des cholinestérases II. Pancréas et suc pancréatique de chien

1955 • 11 citations

Factors influencing the action of neuromuscular blocking substances.

1956 • 11 citations

The Effect of d‐Tubocurarine on the Inhibition of Tetanic Contractions Produced by Cholinesterase Inhibitors.

1957 • 11 citations

Hemmung der Cholinesterase und Pharmakologische Wirkung der Lokalanästhesie

1941 • 11 citations

Some Effects of Acetylcholine, Eserine and Prostigmine when Injected into the Hypothalamus.

1945 • 10 citations

THE ACTION OF ESERINE OR PROSTIGMIN ON THE SUPERIOR CERVICAL GANGLION

1938 • 10 citations

Cholinesterase Activity and Electroencephalograms During Circling Induced by the Intracarotid Injection of Di-Isopropyl Fluorophosphate (DFP)

1954 • 10 citations

Über den Einfluß von Atropin auf die zentrale Hemmung der Atmung durch Anticholinesterasen

1959 • 10 citations

Nikethamide, nocotinamide and some related compounds in anticholinesterase poisoning.

1960 • 10 citations

102 Nature of the cholinergic receptor

1961 • 10 citations

Local Use of Anticholinesterase Agents in Ocular Therapy

1963 • 10 citations

Reversal of effects on the rat nerve-diaphragm preparation produced by methylfluorophosphorylcholines

1959 • 10 citations

Antagonists to Neuromuscular Block Produced by Sarin

1956 • 10 citations

Relationship between peripheral cholinolytic potency and tetraethylpyrophosphate antagonism of a series of atropine substitutes.

1958 • 10 citations

The action of di‐isopropylfluorophosphonate on the central nervous system of the cat

1951 • 10 citations

Darstellung und Pharmakologie des Isobutyryl-3-Oxyphenyltrimethylammoniummethylsulfats und einiger verwandter Verbindungen

1939 • 10 citations

A PHARMACOLOGICAL STRATEGY FOR THE STUDY OF CENTRAL MODULATOR LINKAGES.

1963 • 10 citations

Effect of 3-hydroxy phenyl-dimethylethylammonium chloride (tensilon) in myasthenia gravis.

1951 • 10 citations

THE ACTION OF DRUGS UPON THE OUTPUT OF EPINEPHRIN FROM THE ADRENALS VII. PHYSOSTIGMINE

1921 • 10 citations

The interaction between benzoquinonium and anticholinesterases in skeletal muscle.

1962 • 10 citations

Actions at Autonomic Effector Sites

1963 • 10 citations

Tetraethylammonium and cholinesterase activity.

1951 • 10 citations

Effect of Hormones on Contraction of Striated Muscle and oil Choline Esterase Activity

1943 • 9 citations

THE EFFECT OF CATECHOLAMINES AND ANTICHOLINESTERASES ON THE PERISTALTIC REFLEX OF THE ISOLATED GUINEA-PIG ILEUM.

1964 • 9 citations

Die Wirkung lokaler Mikroelektrophorese von Acetylcholin auf einzelne Neurone des visuellen Cortex

1961 • 9 citations

THE EFFECT OF HEMICHOLINIUM (HC‐3) ON SYMPATHETIC TRANSMISSION AT THE NICTITATING MEMBRANE OF THE RABBIT

1965 • 9 citations

�ber die blutdrucksteigernde Wirkung von Esteraseblockern (E 605, Eserin und Prostigmin)

1955 • 9 citations

Untersuchungen über den Zusammenhang des Acetylcholingehaltes und der Innervation des Herzmuskels in Gewebskulturen

1942 • 9 citations

The Acetylcholinesterase Surface. V. Some New Competitive Inhibitors of Moderate Strength1,2

1956 • 9 citations

The effect of chronic poisoning with di-isopropyl fluorophosphate on neuromuscular function in the cat.

1947 • 9 citations

Protection against alkylphosphate intoxication by intracerebral injection of 1-methyl-2-for-mylpyridinium iodide oxime (2-PAM).

1962 • 9 citations

Metabolic and Acid-Base Changes Following Acute Cholinesterase Inhibition

1957 • 9 citations

The mechanism of action of anticholinesterase compounds on the patellar reflex.

1954 • 8 citations

PHARMACOLOGICAL ACTIONS OF OXAMIDES AND HYDROXYANILINIUM COMPOUNDS AT FROG NEUROMYAL JUNCTION.

1965 • 8 citations

Electrophysiological Evidence Relating to the Rôle of Adrenaline in the Central Nervous System

2008 • 8 citations

Direct Evidence for an Action of Acetylcholine on Motor-nerve Terminals

1964 • 8 citations

Cholinesterase activity of left and right atria of the rabbit's heart

1954 • 8 citations

The chemical agent in the sympathetic control of retraction of the nictitating membrane of the cat

1937 • 8 citations

Pharmacologic actions at various neuroeffectors of single and combined administration of EPN and malathion

1963 • 8 citations

Weitere Beobachtungen über die Phosphinsäuren

1873 • 8 citations

Central effects of diisopropyl-fluorophosphonate (D.F.P.) in Urodele Larvae

1953 • 8 citations

VASODEPRESSION INDUCED BY ACETYLCHOLINE IN THE ATROPINIZED DOG

1963 • 8 citations

Oral and Bronchial Fluids in Poisoning with Anticholinesterases

1955 • 8 citations

Nature of the Acetylcholinesterase Surface. IV. The Control of Enzymatic Inhibition by Basicity in the Substituted Ethylenediamines1,2

1956 • 8 citations

L'epilessia sperimentale

1947 • 8 citations

An attempt to determine the equilibrium constant for the reaction between acetylcholine and the anionic centres of horse plasma cholinesterase

1964 • 8 citations

FACTORS THAT MODIFY TRANSMISSION THROUGH THE SPINAL CORD

1952 • 8 citations

ANALYSIS OF THE VASOPRESSOR AND OTHER "NICOTINIC" ACTIONS OF ACETYLCHOLINE

1940 • 8 citations

Inactivation of cholinesterase by compounds related to neostigmine.

1955 • 8 citations

Actions at Autonomic Ganglia

1963 • 8 citations

Assessment of Direct Cholinesterase Inhibitory Activity by Pupillary Miosis

1957 • 7 citations

Some Observations Concerning the End-Plate Potential

1961 • 7 citations

ACCELERATION OF THE ENZYMIC HYDROLYSIS OF BENZOYLCHOLINE

1956 • 7 citations

A Comparison of the Effects of Atropine with those of Several Central Nervous System Stimulants on Rabbits Exhibiting Forced Circling FoIIowing the Intracarotid Injection of Di-Isopropyl Fluorophosphate

1955 • 7 citations

Therapy of Myasthenia Gravis

1963 • 7 citations

THE ELECTRIC RESPONSES OF THE TAIL PILOMOTORS AND NICTITATING MEMBRANE OF THE CAT

1942 • 7 citations

The Inactivation of Cholinesterase by Morphine, Dilaudid, Codeine and Desomorphine

1944 • 7 citations

ATROPINE‐LIKE ACTIVITY OF SOME ANTICHOLINESTERASES ON THE RABBIT ATRIA

1954 • 7 citations

RECIPROCAL POTENTIATING ACTION OF DEPOLARIZING DRUGS ON THE ISOLATED FROG RECTUS ABDOMINIS MUSCLE

1960 • 7 citations

ON THE ACTION OF PROSTIGMINE ON THE CIRCULATORY SYSTEM

1941 • 7 citations

Studies on the toxicity and pharmacological actions of bis (dimethylamido) fluorophosphate (BFP).

1954 • 7 citations

THE POSSIBILITY OF THE DUAL NATURE OF SYMPATHETIC GANGLION CELLS. II.

1949 • 7 citations

Effect of sarin upon potassium loss by the submandibular gland.

1956 • 7 citations

Tonus, Automatisme et Polarisation du Tissu Myocardique Expériences Sur l'Escargot

1937 • 6 citations

NEUROMUSCULAR TRANSMISSION IN SOMATIC AND AUTONOMIC SYSTEMS

1936 • 6 citations

THE ACTION OF ESERINE SULPHATE ON THE SPINAL CORD OF THE CAT

1954 • 6 citations

Esters of Basically Substituted 3-Pyridols with Physostigmine-like Activity1

1952 • 6 citations

Die Wirkung von Cholinesterasegiften auf Reflexsysteme der tiefspinalen Katze

1957 • 6 citations

A Peptide Material from Myosin Containing Sulfhydryl Groups.

1958 • 6 citations

Weitere Untersuchungen �ber die Kinetik der Cholinesterasen und ihre Beeinflussung durch Atropin

1954 • 6 citations

THE MODIFICATION OF THE HEMODYNAMIC EFFECTS OF ACETYLCHOLINE BY ERGOTAMINE

1940 • 6 citations

Cholinergic Innervation of the Cerebral Cortex

1965 • 6 citations

�ber die Wirkung von Di�thyl-p-nitrophenyl-thiophosphat (E 605) auf R�ckenmarksreflexe an der Katze

1954 • 6 citations

Electrical activity of the "cerveauisole" during caudate nucleus stimulation and its modification by eserine and atropine.

1962 • 5 citations

[Electromyographic analysis of the possible electivity of myasthenic involvement in certain muscular groups].

1960 • 5 citations

Combined Action of Diisopropylfluorophosphate (DFP) and Botulinum Toxin on the Rat Diaphragm Preparation.

1958 • 5 citations

Acute toxicity and anticholinesterase action of O,O-diethyl O-p-(methylsulfinyl)phenyl phosphorothioate (DMSP) and some related compounds

1964 • 5 citations

The effect of di-isopropylfluorophosphate on the neuro-muscular transmission and the importance of cholinesterase for the transmission of single impulses.

1956 • 5 citations

THE EFFECTS OF PHYSOSTIGMINE ON THE MECHANICAL AND ELECTRICAL RESPONSES OF THE CAT NICTITATING MEMBRANE

1964 • 5 citations

Mode of action of antagonists to curare. II. Anti-curare action of hydroxyphenyltrialkyl-ammonium compounds in avian muscle.

1954 • 5 citations

The action of ambenonium (WIN 8077) and related compounds in the mouse.

1957 • 5 citations

THE ANTICHOLINESTERASE ACTIVITY OF POLYMETHYLENE BIS‐QUINOLINIUM SALTS

1955 • 5 citations

Acetylcholin-Aktivierung von Neuronen des visuellen Cortex durch Mikro-Elektrophorese

1964 • 5 citations

INTRODUCTORY REMARKS

1966 • 5 citations

Effect of various drugs in antagonizing the toxicity of TEPP.

1955 • 5 citations

The enzyme systems concerned with acetylcholine synthesis in the atria of the rabbit heart

1959 • 4 citations

Sur la régénération des cholinestérases du sang

1948 • 4 citations

The effectiveness of 2-PAM and TMB-4 as adjuncts to atropine therapy in dogs exposed to Sarin vapor by inhalation.

1962 • 4 citations

An Unusual Cause for Paralysis of the Extremities

1956 • 4 citations

In Vitro Responses of Nictitating Membrane to Drugs and to Denervation

1956 • 4 citations

Further studies on intravenously injected cholinesterase preparations.

1953 • 4 citations

Autonomic ganglionic stimulants.

1954 • 4 citations

The role of acetylcholine and cholinesterase in sympathetic ganglia

1962 • 4 citations

Identification and titration of myasthenic defect by nerve stimulation

1962 • 4 citations

Electrical activity of the cerveau isolé preparation and its relation to the acetylcholine content of the caudate nuclei

1964 • 4 citations

Cholinesterase inhibition by lysergic acid diethylamide.

1954 • 4 citations

Effects of Edrophonium and Neostigmine on Neuromuscular Block in the Cat.

1958 • 4 citations

CHOLINE ACETYLASE ACTIVITY IN THE ATRIA AND ITS POSSIBLE RELATION TO THE MAINTENANCE OF THE MEMBRANE POTENTIAL

1959 • 4 citations

Effects of an inhibitor of the cholinesterase system of brain and cerebrospinal fluid.

1962 • 4 citations

Electrodiagnosis of vitamin E-deficient and denervated skeletal muscle of rabbits

1960 • 3 citations

Increase of Cholinesterase Content in Mouse Liver Homogenates after Incubation.

1956 • 3 citations

Pharmacological behavior of spinal cord potentials relative to reflex and ascending discharge

1960 • 3 citations

The action of NN'-trimethylenebis(4 - hydroxyiminomethylpyridiniumbromide) (TMB - 4) on acute lethal anticholinesterase poisoning in mice

1959 • 3 citations

The effect of atropine upon mammalian striated muscle.

1958 • 3 citations

The Effects of Drugs upon the Eye

1965 • 3 citations

Mécanismes neuro-humoraux et synergie réticulo-corticale

1959 • 3 citations

The Effect of Intracarotid Centripetal Injection of Cholinesterase Inhibitors on the Nuclear Region of the Vestibular Nerve

1957 • 3 citations

Studies on “Syndrome tournant” by IDPN

1960 • 3 citations

Studies on cholinergic blocking substances. VII. Correlations between anticholinergic and cholinesterase-blocking effects.

1955 • 3 citations

Bis-(2-Diaethylaminoaethyl)-benzoldicarbons�ureester-dialkyljodide als spezifische Hemmstoffe der True-Cholinesterase und der Pseudo-Cholinesterase

1953 • 3 citations

THE ANTI-CURARE ACTION OF SUBSTANCE 36

1937 • 3 citations

La localisation histochimique de la cholinestérase dans les fuseaux neuro-musculaires

1954 • 3 citations

Some bisquaternary phthalyl esters as pseudocholinesterase inhibitors and neuromuscular blocking agents.

1959 • 2 citations

Lack of correlation between cholinesterase activity and responsiveness of nerve (lobster) and smooth muscle (rabbit aorta)

1964 • 2 citations

Effets anticholinesterasiques et action sensibilisante sur l'ac�tylcholine de quelques curares de synth�se

1953 • 2 citations

INTERACTIONS OF CHOLINOMIMETIC AND CHOLINERGIC BLOCKING DRUGS AT SYMPATHETIC GANGLIA

1965 • 2 citations

Antispasmodic properties of certain quaternary derivatives of 2,2-diphenyl-4-diisopropylamino-butyramide and other compounds in the isolated perfused guinea-pig lung.

1956 • 2 citations

496 Certain aspects of pharmacology of neuromyal cholinergic receptor

1961 • 2 citations

[On the problem of the effect of galanthamine on the central nervous system].

1961 • 2 citations

Pharmacology of a new bronchoconstrictor drug, hexaethyltetraphosphate.

1947 • 2 citations

Untersuchungen �ber Lokalisation und Funktion der Cholinesterase an der Skeletmuskel-Sehnenverbindung

1960 • 2 citations

RE-EVALUATION OF PHARMACOLOGICAL ACTIONS OF MYTOLON

1957 • 1 citations

[Antitoxic occlusion of the animal organism by centro-vegetative neuroplegia].

1952 • 1 citations

A Biochemical Study on the Effect of Combination of Two Organophosphorus Compounds, EPN [O-ethyl O-P-nitrophenyl Thionobenzene Phosphonate] and Malathion [O,O-dimethyl S-(1,2 dicarbethoxy) Ethyl Dithiophosphate] on Brain Cholinesterases

1961 • 1 citations

EFFECTS OF ENVIRONMENTAL COMPLEXITY AND TRAINING ON BRAIN CHOLINESTERASE AND BRAIN ANATOMY IN THE RAT

1962 • 1 citations

[PEPTIC ULCER AND THE CNS. SOME MODERN VIEWPOINTS].

1963 • 1 citations

Experimental Epilepsy

1924 • 1 citations

Awards of the American Institute of Nutrition

1945 • 1 citations

THE MODIFICATION OF THE ACTION OF OUABAIN IN CARDIAC TISSUE BY ESERINE AND ACETYLCHOLINE

1954 • 1 citations

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Pharmacologic, Toxicologic, and Therapeutic Properties of Anticholinesterase Agents (1967) – Elsevier eBooks | Metascience Observatory Explorer