A comparative study of some pyridinium oximes as reactivators of phosphorylated acetylcholinesterase and as antidotes in sarin poisoning

Ted A. Loomis; Michael J. Welsh; Greg Miller

doi:10.1016/0041-008x(63)90004-8

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A comparative study of some pyridinium oximes as reactivators of phosphorylated acetylcholinesterase and as antidotes in sarin poisoning

Ted A. Loomis, Michael J. Welsh, Greg Miller

DOI: 10.1016/0041-008x(63)90004-8

Toxicology and Applied Pharmacology

Data up to Jan 2025

Published1963

Citations12

References7

Fields

Chemistry Medicine Pharmacology Medicinal chemistry Biochemistry

Total Citations Per Year

Abstract

References (7)

A powerful reactivator of alkylphosphate-inhibited acetylcholinesterase

1955 • 502 citations

Pyridinium Aldoximes¹

1958 • 153 citations

Verbesserung und Erweiterung der Bromierungsmethode mit Brom‐succinimid

1946 • 118 citations

Reactivation of alkylphosphate inhibited acetylcholinesterase by bis quaternary derivatives of 2-PAM and 4-PAM

1959 • 50 citations

Effects of 1,1'-trimethylene bis(4-formylpyridinium bromide) dioxime (TMB-4) on cholinesterase activity and neuromuscular block following poisoning with sarin and DEP.

1960 • 22 citations

OXIMES OF αω‐DIQUATERNARY ALKANE SALTS AS ANTIDOTES TO ORGANOPHOSPHATE ANTICHOLINESTERASES

1959 • 21 citations

Parasympatholytic Effects of TMB‐4 [1,1‐Trimethylene‐bis (4‐formylpyridinium Bromide)‐dioximel and some related Oximes in the Cat *).

1960 • 21 citations

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