MiniReview: Antiviral Targets Series, Number 1

On the size of the active site in proteases. I. Papain

1967 • 5,150 citations

Conserved Folding in Retroviral Proteases: Crystal Structure of Synthetic HIV-1 Protease

1989 • 1,155 citations

Structure of Complex of Synthetic HIV-1 Protease with a Substrate-Based Inhibitor at 2.3 Å Resolution

1989 • 683 citations

A structural model for the retroviral proteases

1987 • 594 citations

X-ray analysis of HIV-1 proteinase at 2.7 Å resolution confirms structural homology among retroviral enzymes

1989 • 453 citations

Crystal structure of a retroviral protease proves relationship to aspartic protease family

1989 • 345 citations

Sensitive, soluble chromogenic substrates for HIV-1 proteinase.

1990 • 200 citations

Molecular Modeling of the HIV-1 Protease and Its Substrate Binding Site

1989 • 168 citations

Effective blocking of HIV‐1 proteinase activity by characteristic inhibitors of aspartic proteinases

1989 • 166 citations

Activity of purified biosynthetic proteinase of human immunodeficiency virus on natural substrates and synthetic peptides.

1989 • 166 citations

Peptide substrates and inhibitors of the HIV-1 protease

1989 • 162 citations

Viral proteinases: weakness in strength

1990 • 123 citations

Processing of the structural proteins of human immunodeficiency virus type 1 in the presence of monensin and cerulenin.

1988 • 65 citations

X-ray studies of aspartic proteinase-statine inhibitor complexes

1989 • 56 citations

The selectivity of statine-based inhibitors against various human aspartic proteinases

1990 • 41 citations

Synthetic non-peptide inhibitors of HIV protease

1989 • 38 citations

Substitution mutations of the highly conserved arginine 87 of HIV-1 protease result in loss of proteolytic activity

1989 • 35 citations

Inhibition of the aspartic proteinase from HIV‐2

1989 • 28 citations