Colon Cancer as a Model for Resistance to Antineoplastic Drugs

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells

1986 • 1,903 citations

Expression of a multidrug-resistance gene in human tumors and tissues.

1987 • 1,547 citations

Expression of Multidrug Resistance Gene in Human Cancers

1989 • 1,305 citations

Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins

1986 • 1,058 citations

Overexpression of a novel anionic glutathione transferase in multidrug-resistant human breast cancer cells.

1986 • 791 citations

Oxidative destruction of DNA by the adriamycin-iron complex

1984 • 173 citations

The basis of multidrug resistance in mammalian cells: Homology with bacterial transport

1986 • 134 citations

DNA damage by superoxide-generating systems in relation to the mechanism of action of the anti-tumour antibiotic adriamycin

1983 • 84 citations

Clinical drug development: an analysis of phase II trials, 1970-1985.

1987 • 79 citations

Reduction of O2 by iron-adriamycin.

1984 • 77 citations

Radiosensitization of Human Fibroblasts by 3-Aminobenzamide: An Inhibitor of Poly(ADP-Ribosylation)

1985 • 46 citations

Ascorbate potentiates DNA damage by 1-methyl-1-nitrosourea in vivo and generates DNA strand breaks in vitro

1987 • 12 citations

Biology and Treatment of Colorectal Cancer Metastasis

1986 • 7 citations