Glutathione and tissue toxicity

[44] Glutathione peroxidase

1981 • 2,990 citations

The Glutathione Status of Cells

1978 • 1,218 citations

The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells.

1982 • 893 citations

Intracellular production of superoxide radical and of hydrogen peroxide by redox active compounds

1979 • 595 citations

Functions of glutathione. Biochemical, physiological, toxicological and clinical aspects

1984 • 595 citations

Bleb Formation in Hepatocytes During Drug Metabolism Is Caused by Disturbances in Thiol and Calcium Ion Homeostasis

1982 • 553 citations

Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes

1984 • 411 citations

Menadione-induced cytotoxicity is associated with protein thiol oxidation and alteration in intracellular Ca2+ homeostasis

1984 • 376 citations

Biochemical Mechanisms of Drug Toxicity

1974 • 337 citations

The Transport of Oxidized Glutathione from Human Erythrocytes

1969 • 256 citations

Oxidation of glutathione during hydroperoxide metabolism

1984 • 243 citations

Glutathione Transferases

1980 • 242 citations

Glutathione Peroxidase

1980 • 235 citations

Inhibition of ATP-dependent microsomal Ca2+ sequestration during oxidative stress and its prevention by glutathione.

1983 • 176 citations

Critical role of sulfhydryl group(s) in ATP‐dependent Ca²⁺ sequestration by the plasma membrane fraction from rat liver

1983 • 172 citations

The role of methionine in glutathione biosynthesis by isolated hepatocytes

1977 • 159 citations

The metabolism of menadione impairs the ability of rat liver mitochondria to take up and retain calcium.

1982 • 159 citations

Metabolic activation and hepatotoxicity

1979 • 158 citations

Metabolism of glutathione and a glutathione conjugate by isolated kidney cells.

1979 • 140 citations

A phosphotyrosyl‐protein phosphatase activity associated with acid phosphatase from human prostate gland

1984 • 112 citations

Increase in cytosolic Ca²⁺ concentration during t‐butyl hydroperoxide metabolism by isolated hepatocytes involves NADPH oxidation and mobilization of intracellular Ca²⁺ stores

1984 • 107 citations

Competition between transport of glutathione disulfide (GSSG) and glutathione S‐conjugates from perfused rat liver into bile

1982 • 100 citations

The absolute asymmetry of orientation of gamma-glutamyltranspeptidase and aminopeptidase on the external surface of the rat renal brush border membrane.

1980 • 100 citations

Turnover and functions of glutathione studied with isolated hepatic and renal cells.

1983 • 87 citations

Prostaglandin synthetase catalyzed activation of paracetamol

1982 • 85 citations

Biochemistry of Glutathione

1975 • 83 citations

Characteristics of glutathione biosynthesis by freshly isolated rat kidney cells.

1980 • 66 citations

Turnover of Cellular Glutathione in Isolated Rat‐Kidney Cells

1981 • 37 citations

Glutathione conjugation by isolated lung cells and the isolated, perfused lung

1984 • 34 citations

Structure, Function, and Regulation of Phosphorylase Kinase

1982 • 33 citations

Topology and Function of Renal γ-Glutamyl Transpeptidase

1978 • 29 citations