Phenylalanine hydroxylase in liver cells. Correlation of glucagon-stimulated enzyme phosphorylation with expressed activity

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Removal of Fatty Acids from Serum Albumin by Charcoal Treatment

1967 • 2,098 citations

A fluorometric method for the estimation of tyrosine in plasma and tissues.

1957 • 973 citations

Distinct Mediating Systems for the Transport of Neutral Amino Acids by the Ehrlich Cell

1963 • 839 citations

Hydroxylation-Induced Migration: The NIH Shift

1967 • 519 citations

Use of Isolated Liver Cells and Kidney Tubules in Metabolic Studies

1976 • 252 citations

Neutral amino acid transport. Characterization of the A and L systems in isolated rat hepatocytes.

1977 • 216 citations

A simple purification of phenylalanine hydroxylase by substrate-induced hydrophobic chromatography.

1979 • 191 citations

Some Special Kinetic Problems of Transport

1969 • 173 citations

In vitro activation of rat liver phenylalanine hydroxylase by phosphorylation.

1976 • 149 citations

Glucagon and the Ca2+-linked hormones angiotensin II, norepinephrine, and vasopressin stimulate the phosphorylation of distinct substrates in intact hepatocytes.

1982 • 126 citations

Effects of lysosomotropic monoamines, diamines, amino alcohols, and other amino compounds on protein degradation and protein synthesis in isolated rat hepatocytes.

1980 • 91 citations

Transport of Hexoses across the Liver‐Cell Membrane

1977 • 90 citations

Glucagon stimulation of rat hepatic phenylalanine hydroxylase through phosphorylation in vivo.

1978 • 88 citations

Comparative studies of alanine and alpha-aminoisobutyric acid uptake by freshly isolated rat liver cells.

1979 • 73 citations

Regulation of phenylalanine hydroxylase activity by phenylalanine in vivo, in vitro, and in perfused rat liver.

1982 • 71 citations

A simple radioisotope assay for phenylalanine hydroxylase

1967 • 68 citations

The metabolism of L-tryptophan by isolated rat liver cells. Effect of albumin binding and amino acid competition on oxidatin of tryptophan by tryptophan 2,3-dioxygenase

1980 • 63 citations

Relationship between the substrate activation site and catalytic site of phenylalanine hydroxylase.

1980 • 61 citations

The metabolic integrity of hepatocytes in sustained incubations

1977 • 59 citations

Relationship between the multiple forms of rat hepatic phenylalanine hydroxylase and degree of phosphorylation.

1980 • 52 citations

The transport of branched‐chain amino acids into isolated rat liver cells

1977 • 46 citations

Determination of the phosphate content of purified proteins

1982 • 45 citations

A simple assay method for determination of the specific radioactivity of the γ-phosphate group of 32P-labelled ATP.

1983 • 40 citations

Iron-dependent regulation of rat liver phenylalanine hydroxylase activity in vivo, in vitro, and in perfused liver.

1982 • 40 citations

Phenylalanine metabolism in isolated rat liver cells. Effects of glucagon and diabetes

1981 • 38 citations

Tyrosine aminotransferase as the rate‐limiting step for tyrosine catabolism in isolated rat liver cells

1981 • 38 citations

Hepatic pyruvate kinase. Quantitative measurements of phosphorylation in vitro and in the isolated rat hepatocyte.

1982 • 36 citations

Hepatic phenylalanine 4-monooxygenase is a phosphoprotein.

1976 • 30 citations

Ligand effects on the limited proteolysis of phenylalanine hydroxylase: Evidence for multiple conformational states

1983 • 28 citations

A simple and rapid assay for tyrosine aminotransferase

1977 • 23 citations

Hormonal control of phenylalanine hydroxylase activity in isolated rat hepatocytes

1980 • 18 citations

On the phosphate content of rat liver phenylalanine hydroxylase purified by hydrophobic chromatography

1981 • 17 citations

Relationship between phosphorylation of tyrosine aminotransferase and regulation of its synthesis by cyclic AMP and hormones.

1978 • 10 citations