Macrophage and Dendritic Cell Populations in the Respiratory Tract

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

Cellular Events in the Bronchi in Mild Asthma and after Bronchial Provocation

1989 • 1,158 citations

Macrophages and Polymorphonuclear Neutrophils in Lung Defense and Injury

1990 • 1,091 citations

Purification and properties of colony-stimulating factor from mouse lung-conditioned medium.

1977 • 624 citations

Downregulation of the antigen presenting cell function(s) of pulmonary dendritic cells in vivo by resident alveolar macrophages.

1993 • 540 citations

Macrophage production of transforming growth factor beta and fibroblast collagen synthesis in chronic pulmonary inflammation.

1989 • 502 citations

Rapid dendritic cell recruitment is a hallmark of the acute inflammatory response at mucosal surfaces.

1994 • 395 citations

Nitric oxide production is required for murine resident peritoneal macrophages to suppress mitogen-stimulated T cell proliferation. Role of IFN-gamma in the induction of the nitric oxide-synthesizing pathway.

1991 • 384 citations

Origin and steady-state turnover of class II MHC-bearing dendritic cells in the epithelium of the conducting airways.

1994 • 354 citations

Studies on the density, distribution, and surface phenotype of intraepithelial class II major histocompatibility complex antigen (Ia)-bearing dendritic cells (DC) in the conducting airways.

1991 • 316 citations

Tumor Necrosis Factor Causes Bronchial Hyperresponsiveness in Rats

1992 • 287 citations

MHC class II antigen-bearing dendritic cells in pulmonary tissues of the rat. Regulation of antigen presentation activity by endogenous macrophage populations.

1988 • 285 citations

Vitamin D Conversion by Sarcoid Lymph Node Homogenate

1984 • 265 citations

Induction of macrophage production and proliferation by a purified colony stimulating factor

1978 • 225 citations

Immunohistochemical Characterization of the Cellular Infiltration in Asthmatic Bronchi

1992 • 224 citations

Cellular and biochemical characteristics of bronchoalveolar lavage fluid in symptomatic nonallergic asthma

1991 • 200 citations

Accumulation of Langerhans' Cells on the Epithelial Surface of the Lower Respiratory Tract in Normal Subjects in Association with Cigarette Smoking

1988 • 195 citations

Development of the airway intraepithelial dendritic cell network in the rat from class II major histocompatibility (Ia)-negative precursors: differential regulation of Ia expression at different levels of the respiratory tract.

1994 • 190 citations

Ia‐positive dendritic cells form a tightly meshed network within the human airway epithelium

1989 • 188 citations

Down-regulation of immune responses in the lower respiratory tract: the role of alveolar macrophages.

1986 • 187 citations

Primary sensitisation to inhalant allergens during infancy

1990 • 176 citations

Localization of T cells, macrophages and dendritic cells in rat respiratory tract tissue: implications for immune function studies.

1987 • 173 citations

Inhibition of the immunosuppressive activity of resident pulmonary alveolar macrophages by granulocyte/macrophage colony-stimulating factor.

1993 • 170 citations

Cigarette Smoking-induced Changes in the Number and Differentiated State of Pulmonary Dendritic Cells/ Langerhans Cells

1989 • 170 citations

Resident macrophage proliferation in mice depleted of blood monocytes by strontium-89.

1982 • 166 citations

Normal human alveolar macrophages obtained by bronchoalveolar lavage have a limited capacity to release interleukin-1.

1984 • 166 citations

Characterization of mononuclear phagocyte subpopulations in the human lung by using monoclonal antibodies: changes in alveolar macrophage phenotype associated with pulmonary sarcoidosis.

1985 • 163 citations

Enhanced alveolar macrophage-mediated antigen-induced T-lymphocyte proliferation in sarcoidosis.

1985 • 150 citations

A Contiguous Network of Dendritic Antigen-Presenting Cells within the Respiratory Epithelium

1990 • 144 citations

Characterization of murine lung dendritic cells: similarities to Langerhans cells and thymic dendritic cells.

1990 • 134 citations

Regulation of antigen-presenting cell function(s) in lung and airway tissues

1993 • 124 citations

Intraepithelial airway dendritic cells: a distinct subset of pulmonary dendritic cells obtained by microdissection.

1992 • 116 citations

Differential Production of Tumor Necrosis Factor, Macrophage Colony Stimulating Factor, and Interleukin 1 by Human Alveolar Macrophages

1989 • 115 citations

T cell activation by antigen-presenting cells from lung tissue digests: suppression by endogenous macrophages.

1985 • 110 citations

Regulation of immune response to inhaled antigen by alveolar macrophages: differential effects of in vivo alveolar macrophage elimination on the induction of tolerance vs. immunity

1991 • 105 citations

Heterogeneity of Immunologic Function Among Subfractions of Normal Rat Alveolar Macrophages^1–3

1984 • 97 citations

Regulation of IgE production in pre‐sensitized animals: in vivo elimination of alveolar macrophages preferentially increases IgE responses to inhaled allergen*

1992 • 96 citations

Spectrum of Immunoregulatory Functions and Properties of Human Alveolar Macrophages

1987 • 96 citations

Dendritic Cells in the Respiratory Tract

1990 • 85 citations

Alveolar macrophages from humans and rodents selectively inhibit T-cell proliferation but permit T-cell activation and cytokine secretion.

1995 • 85 citations

Regulation of T-cell function in lung tissue by pulmonary alveolar macrophages.

1993 • 82 citations

Immunosuppressive activity induced by nitric oxide in culture supernatant of activated rat alveolar macrophages.

1992 • 81 citations

Airway Macrophages

1984 • 77 citations

Human pulmonary macrophages utilize prostaglandins and transforming growth factor β1 to suppress lymphocyte activation

1993 • 74 citations

The Significance of Local Resident Pulmonary Alveolar Macrophage Proliferation to Population Renewal

1986 • 71 citations

Bronchoalveolar cells from sarcoid patients demonstrate enhanced antigen presentation.

1985 • 70 citations

Fluctuation of the number of CD-1(T6)-positive dendritic cells, presumably Langerhans cells, in the nasal mucosa of patients with an isolated grass-pollen allergy before, during, and after the grass-pollen season

1989 • 70 citations

A quantitative evaluation of pulmonary macrophage kinetics.

1983 • 62 citations

Decreased suppressor cell activity of alveolar macrophages in bronchial asthma.

1984 • 60 citations

Subpopulations of lymphoid and non-lymphoid cells in bronchus-associated lymphoid tissue (BALT) of the mouse.

1988 • 58 citations

Studies on the surface phenotype and functions of dendritic cells in parenchymal lung tissue of the rat.

1992 • 49 citations

Expression and Regulation of Human Alveolar Macrophage-derived Interleukin-1 Receptor Antagonist

1992 • 48 citations

Monoclonal antibodies distinguish macrophages and epithelioid cells in sarcoidosis and leprosy.

1987 • 47 citations

ALVEOLAR MACROPHAGES: FUNCTIONAL HETEROGENEITY WITHIN MACROPHAGE POPULATIONS FROM RAT LUNG

1982 • 45 citations

Heterogeneity Among Alveolar Macrophages in Humoral and Cell-Mediated Immune Responses: Separation of Functional Subpopulations by Density Gradient Centrifugation on Percoll

1984 • 45 citations

Accessory Cells of the Lung. I. Interferon-gamma Increases Ia⁺ Dendritic Cells in the Lung Without Augmenting their Accessory Activities

1991 • 44 citations

IL-1 and IL-1 Inhibitory Activity in the Culture Supernatants of Alveolar Macrophages from Patients with Interstitial Lung Diseases*

1991 • 42 citations

Requirement for Cell-to-Cell Contact for the Immunosuppressive Activity of Human Alveolar Macrophages

1991 • 40 citations

A role for TGF-beta in the suppression by murine bronchoalveolar cells of lung dendritic cell initiated immune responses.

1993 • 40 citations

Adhesion Molecules on Human Lung Dendritic Cells and Their Role for T-Cell Activation

1992 • 39 citations

Effect of Bacillus Calmette-Guérin Inoculation on Numbers of Dendritic Cells in Bronchoalveolar Lavages of Rats

1992 • 38 citations

Suppression of T-cell activation by pulmonary alveolar macrophages: dissociation of effects on TcR, IL-2R expression, and proliferation

1994 • 38 citations

Interleukin-1-beta Gene Expression in Human Monocytes and Alveolar Macrophages from Normal Subjects and Patients with Sarcoidosis

1988 • 38 citations

Alveolar macrophages down-regulate local pulmonary immune responses against intratracheally administered T-cell-dependent, but not T-cell-independent antigens.

1992 • 32 citations

ATPase and Morphologic Changes Induced by UVB on Langerhans Cells in Guinea Pigs

1985 • 29 citations

Accessory Cells of the Lung. II. Ia⁺ Pulmonary Dendritic Cells Display Cell Surface Antigen Heterogeneity

1991 • 28 citations

The Ontogeny of Pulmonary Alveolar Macrophages in Parabiotic Mice

1986 • 28 citations

Review of the Significance of Pulmonary Intravascular Macrophages with Respect to Animal Species and Age

1989 • 27 citations

Cell Kinetics of the Inflammatory Reaction

1989 • 25 citations

Alveolar macrophages. VI. Regulation of alveolar macrophage-mediated suppression of lymphocyte proliferation by a putative T cell.

1981 • 23 citations

Dissociation between Allogeneic T Cell Stimulation and Interleukin-1 or Tumor Necrosis Factor Production by Human Lung Dendritic Cells

1990 • 21 citations

Zonal distribution of alveolar macrophages, type II pneumonocytes, and alveolar septal connective tissue gaps in adult human lungs.

1986 • 20 citations

Dendritic Cells in Cutaneous, Lymph Node and Pulmonary Lesions of Sarcoidosis

1987 • 19 citations

The surface phenotypic characterization of lung macrophages in C3H/HeJ mice.

1991 • 19 citations

Changes in lung macrophages during disease

1990 • 18 citations

Heterogeneity of the Radiosensitivity and Origins of Tissue Macrophage Colony-Forming Cells.

1992 • 10 citations

Changes in lung macrophages during disease

1990 • 7 citations

Specificity of Immunosuppression by Human Alveolar Cells

1984 • 2 citations