Embryonal Carcinoma Cells: The Malignant Counterparts of ES and EG Cells

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

2000 • 3,564 citations

Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro

2000 • 2,733 citations

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

1991 • 1,693 citations

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

1998 • 1,518 citations

MULTIPOTENTIALITY OF SINGLE EMBRYONAL CARCINOMA CELLS.

1964 • 773 citations

Stage-specific embryonic antigen involves αl→ 3 fucosylated type 2 blood group chains

1981 • 612 citations

The development of transplantable teratocarcinomas from intratesticular grafts of pre- and postimplantation mouse embryos

1970 • 565 citations

Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cells

1990 • 524 citations

Transplantation of Cryopreserved Human Embryonal Carcinoma-Derived Neurons (NT2N Cells) Promotes Functional Recovery in Ischemic Rats

1998 • 361 citations

Localization to Xq27 of a susceptibility gene for testicular germ-cell tumours

2000 • 272 citations

GLP-1 is localized to the mitotic region of the C. elegans germ line

1994 • 247 citations

Cytomegalovirus Replicates in Differentiated But Not in Undifferentiated Human Embryonal Carcinoma Cells

1984 • 196 citations

Oligosaccharides containing fucose linked α(1–3) and α(1–4) to N-acetylglucosamine cause decompaction of mouse morulae

1984 • 193 citations

i(12p): Specific chromosomal marker in seminoma and malignant teratoma of the testis?

1983 • 189 citations

Transplanted human neurons derived from a teratocarcinoma cell line (NTera‐2) mature, integrate, and survive for over 1 year in the nude mouse brain

1995 • 179 citations

Nonrandom abnormalities in chromosome 1 in human testicular cancers.

1980 • 155 citations

The human embryonal carcinoma marker antigen TRA-1-60 is a sialylated keratan sulfate proteoglycan.

1999 • 133 citations

RETENTION OF MULTIPLE DEVELOPMENTAL POTENTIALITIES BY CELLS OF A MOUSE TESTICULAR TERATOCARCINOMA DURING PROLONGED CULTURE in vitro AND THEIR EXTINCTION UPON HYBRIDIZATION WITH CELLS OF PERMANENT LINES

1967 • 129 citations

The origin and migration of primordial germ cells in the mouse

1998 • 124 citations

High-molecular-weight glycoproteins of human teratocarcinoma defined by monoclonal antibodies to carbohydrate determinants.

1985 • 109 citations

Negative and positive regulation by a short segment in the 5'-flanking region of the human cytomegalovirus major immediate-early gene.

1987 • 108 citations

Expression of Wnt and Notch pathway genes in a pluripotent human embryonal carcinoma cell line and embryonic stem cells

2003 • 103 citations

Developmental regulation of neurogenesis in the pluripotent human embryonal carcinoma cell line NTERA‐2

2000 • 95 citations

Overrepresentation of chromosome 12p sequences and karyotypic evolution in i(12p)-negative testicular germ-cell tumors revealed by fluorescence in situ hybridization

1993 • 93 citations

Constitutive and retinoic acid-inducible expression of cytomegalovirus immediate-early genes in human teratocarcinoma cells

1986 • 91 citations

Experimental Production of Testicular Teratomas in Mice of Strains 129, A/He, and Their F<sub>1</sub> Hybrids<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1970 • 78 citations

Inhibition of proliferation and induction of differentiation of pluripotent human embryonal carcinoma cells by osteogenic protein-1 (or bone morphogenetic protein-7).

1994 • 73 citations

Antigen expression by somatic cell hybrids of a murine embryonal carcinoma cell with thymocytes and L cells

1980 • 69 citations

Red Cell Antigens P (Globoside) and Luke: Identification by Monoclonal Antibodies Defining the Murine Stage‐Specific Embryonic Antigens ‐3 and ‐4 (SSEA‐3 and SSEA‐4)¹

1986 • 66 citations

[Mouse teratocarcinoma: differentiation in cultures of a multipotential primitive cell line (author's transl)].

1975 • 62 citations

Chromosomal constitution and developmental potential of human germ cell tumors and teratomas

1997 • 61 citations

Ultrastructural differentiation of a clonal human embryonal carcinoma cell line in vitro.

1983 • 54 citations

Retinoic acid fails to induce differentiation in human teratocarcinoma cell lines that express high levels of a cellular receptor protein

1983 • 51 citations

Alkaline phosphatase isozymes as possible markers of differentiation in human testicular teratocarcinoma cell lines

1981 • 51 citations

Molecular Cytogenetics of Human Germ Cell Tumours: i(12p) and Related Chromosomal Anomalies

1993 • 49 citations

Presumptive neurons derived by differentiation of a human embryonal carcinoma cell line exhibit tetrodotoxin-sensitive sodium currents and the capacity for regenerative responses

1989 • 42 citations

The biology of testicular cancer. I. Behavior after transplantation.

1957 • 35 citations

Regulation of Intracellular Ca²⁺ in Response to Muscarinic and Glutamate Receptor Agonists During the Differentiation of NTERA2 Human Embryonal Carcinoma Cells into Neurons

1996 • 30 citations

Brachyury is expressed by human teratocarcinoma cells in the absence of mesodermal differentiation.

2000 • 26 citations

Hepatocytic Transcription Factor Expression in Human Embryonal Carcinoma and Yolk Sac Carcinoma Cell Lines: Expression of HNF-3α in Models of Early Endodermal Cell Differentiation

1994 • 26 citations

Induction of mcl1/EAT, Bcl-2 Related Gene, by Retinoic Acid or Heat Shock in the Human Embryonal Carcinoma Cells, NCR-G3.

1996 • 24 citations

Importance of a new tumor market TRA-1-60 in the follow-up of patients with clinical stage I nonseminomatous testicular germ cell tumors

1997 • 22 citations

[Differentiation of human germ cell tumor cells].

1989 • 7 citations