Glycoprotein Synthesis and Endothelial Cell Function: Influence of Thrombin and Melittin on Release of Glycoconjugates, Activity of Converting Enzyme, and Cell Morphology

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Binding of soluble form of fibroblast surface protein, fibronectin, to collagen

1977 • 1,972 citations

Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin.

1978 • 1,559 citations

Bee and Wasp Venoms

1972 • 1,525 citations

Synthesis of Antihemophilic Factor Antigen by Cultured Human Endothelial Cells

1973 • 1,303 citations

Angiogenesis in vitro

1980 • 1,041 citations

International cell biology 1976–1977

1978 • 762 citations

Stimulation of Endothelial Cell Prostacyclin Production by Thrombin, Trypsin, and the Ionophore A 23187

1978 • 715 citations

Angiotensin-Converting Enzyme: Vascular Endothelial Localization

1976 • 644 citations

Synthesis of prostaglandin I2 (prostacyclin) by cultured human and bovine endothelial cells.

1977 • 625 citations

Synthesis of von Willebrand Factor by Cultured Human Endothelial Cells

1974 • 472 citations

Response to injury and atherogenesis.

1977 • 459 citations

Synthesis of fibronectin by cultured human endothelial cells.

1978 • 458 citations

Mast cell heparin stimulates migration of capillary endothelial cells in vitro.

1980 • 445 citations

Selection and characterization of bovine aortic endothelial cells

1978 • 417 citations

Heparan sulfates of cultured cells. I. Membrane-associated and cell-sap species in Chinese hamster cells

1971 • 313 citations

Morphological appearance, growth behavior and migratory activity of human tumor cells maintained on extracellular matrix versus plastic

1980 • 312 citations

Control of proliferation of human vascular endothelial cells. Characterization of the response of human umbilical vein endothelial cells to fibroblast growth factor, epidermal growth factor, and thrombin

1978 • 312 citations

Subcellular localization of pulmonary antiotensin-converting enzyme (kininase II)

1975 • 300 citations

Binding and Factor XIII _a -Mediated Cross-Linking of a 27-Kilodalton Fragment of Fibronectin to Staphylococcus aureus

1980 • 291 citations

Identification, localization, and role of fibronectin in cultured bovine endothelial cells.

1978 • 258 citations

Effect of bradykinin and thrombin on prostacyclin synthesis in endothelial cells from calf and pig aorta and human umbilical cord vein

1980 • 249 citations

Binding of heparin on the surface of cultured human endothelial cells

1978 • 236 citations

Human Pulmonary Endothelial Cells in Culture

1980 • 233 citations

The Structure and Properties of the Cell Surface Coat

1976 • 226 citations

Sulfated mucopolysaccharide synthesis and secretion in endothelial cell cultures

1973 • 220 citations

The anticoagulant effect of heparan sulfate and dermatan sulfate

1976 • 219 citations

Synthesis of basement membrane collagen by cultured human endothelial cells.

1976 • 209 citations

Metabolism of vasoactive peptides by human endothelial cells in culture. Angiotensin I converting enzyme (kininase II) and angiotensinase.

1977 • 202 citations

The collagenous components of the subendothelium. Correlation of structure and function.

1980 • 197 citations

Binding of human thrombin to cultured human endothelial cells.

1979 • 193 citations

Transport of solutes through cartilage: permeability to large molecules.

1976 • 192 citations

Cell surface modification by endo-beta-galactosidase. Change of blood group activities and release of oligosaccharides from glycoproteins and glycosphingolipids of human erythrocytes.

1979 • 187 citations

Biochemical and immunological characterization of human opsonic alpha2SB glycoprotein: its identity with cold-insoluble globulin.

1978 • 187 citations

The Poly(glycosyl) Chains of Glycoproteins.

1978 • 186 citations

Effect of Aspirin on Thrombin-Induced Adherence of Platelets to Cultured Cells from the Blood Vessel Wall

1978 • 184 citations

Cell Aggregation: Role of Acid Mucopolysaccharides

1972 • 182 citations

Platelet and Blood Vessel Arachidonate Metabolism and Interactions

1979 • 181 citations

Characterization of the collagen synthesized by endothelial cells in culture.

1976 • 174 citations

Activation of high levels of endogenous phospholipase A2 in cultured cells.

1979 • 174 citations

The role of hyaluronic acid in intercellular adhesion of cultured mouse cells

1978 • 160 citations

Enzymatic degradation of heparin-related mucopolysaccharides from the surface of endothelial cell cultures

1975 • 157 citations

The effect of fibrin on cultured vascular endothelial cells

1979 • 152 citations

Binding of platelet factor 4 to cultured human umbilical vein endothelial cells

1980 • 140 citations

Effects of tunicamycin on the biosynthesis of glycosaminoglycans by embryonic chick cornea

1978 • 140 citations

A unique, pepsin-sensitive collagen synthesized by aortic endothelial cells in culture

1980 • 138 citations

A New Antigen System Expressed in Human Endothelial Cells

1977 • 137 citations

Collagen synthesis by bovine aortic endothelial cells in culture

1979 • 137 citations

Relationship of transformation, cell density, and growth control to the cellular distribution of newly synthesized glycosaminoglycan.

1976 • 136 citations

Synthesis of cold-insoluble globulin by cultured calf endothelial cells.

1978 • 132 citations

Cell surface changes correlated with density-dependent growth inhibition. Glycosaminoglycan metabolism in 3T3, SV3T3, and Con A selected revertant cells

1975 • 132 citations

Characterization of the collagen chains synthesized by cultured smooth muscle cells derived from rhesus monkey thoracic aorta

1978 • 131 citations

Metabolism of sulfated glycosaminoglycans in cultured endothelial cells and smooth muscle cells from bovine aorta

1978 • 128 citations

Unified concept on the role of acid mucopolysaccharides and connective tissue proteins in the accumulation of lipids, lipoproteins, and calcium in the atherosclerotic plaque

1976 • 125 citations

Use of a radioimmunoassay to study thrombin-induced release of PGI2 from cultured endothelium

1979 • 123 citations

Substrate-attached glycoproteins from normal and virus-transformed cells

1974 • 122 citations

Composition and distribution of glycosaminoglycans in cultures of human normal and malignant glial cells

1978 • 119 citations

Studies of morphologically atypical (“sprouting”) cultures of bovine aortic endothelial cells. Growth characteristics and connective tissue protein synthesis

1980 • 112 citations

Isolation and tissue localization of type AB2 collagen from normal lung parenchyma.

1979 • 110 citations

Transformation of cultured human vascular endothelium by SV40 DNA

1976 • 110 citations

Effect of a platelet endoglycosidase on cell surface associated heparan sulphate of human cultured endothelial and glial cells

1977 • 108 citations

Effect of thrombin on the fibrinolytic activity of cultured bovine endothelial cells.

1979 • 107 citations

Stimulation of Extracellular Matrix Synthesis in the Developing Cornea by Glycosaminoglycans

1974 • 99 citations

Fibronectin and Atherosclerosis

1980 • 86 citations

Endothelial Damage and Thrombocyte Adhesion in Pigeon Atherosclerosis

1977 • 77 citations

Production and secretion of chondroitin sulfates and dermatan sulfate by established mammalian cell lines

1971 • 72 citations

Characterization of cell matrix associated collagens synthesized by aortic endothelial cells in culture

1981 • 68 citations

Heparin Neutralization of PGI ₂ : Effects Upon Platelets

1979 • 67 citations

Antithrombin III in fresh and cultured human endothelial cells: A natural anticoagulant from the vascular endothelium

1979 • 65 citations

Surface charge properties of the luminal front of blood vessel, walls: An electron microscopical analysis

1975 • 64 citations

The effect of cell density on net rates of glycosaminoglycan synthesis and secretion by cultured rat fibroblasts.

1980 • 63 citations

Distribution and movement of anionic cell surface sites in cultured human vascular endothelial cells

1979 • 60 citations

The isolation of vascular endothelial cell lines with altered cell surface and platelet-binding properties

1978 • 57 citations

Internalization and degradation of thrombin and up regulation of thrombin-binding sites in corneal endothelial cells.

1981 • 51 citations

Activation of membrane-bound kallikrein and renin in the kidney.

1980 • 50 citations

Variant endothelial cells. Fibronectin as a transducer of signals for migration and neovascularisation

1980 • 50 citations

Inhibitory effects of human aortic and venous acid glycosaminoglycans on thrombus formation

1972 • 50 citations

Heparin and dextran sulfate antagonize PGI2 inhibition of platelet aggregation

1979 • 49 citations

ROLE OF THE HIGH‐MOLECULAR‐WEIGHT GLYCOPROTEIN IN CELLULAR MORPHOLOGY, ADHESION, AND DIFFERENTIATION*

1978 • 43 citations

Synthesis of interstitial collagens by pig aortic endothelial cells in culture

1978 • 42 citations

Type IV and type "A-B" collagens do not elicit platelet aggregation or the serotonin release reaction.

1979 • 41 citations

Evidence that ADP hydrolysis by human cells is related to thrombogenic potential

1978 • 38 citations

Cell surface glycosaminoglycans: Identification and organization in cultured human embryo fibroblasts

1977 • 37 citations

Comparative degradation of adenylnucleotides by cultured endothelial cells and fibroblasts

1978 • 35 citations

Covalent binding of thrombin to specific sites on corneal endothelial cells

1981 • 35 citations

Cell‐surface glycosaminoglycans: Turnover in cultured human embryo fibroblasts (IMR‐90)

1980 • 32 citations

A variant vascular endothelial cell line with altered growth characteristics

1979 • 31 citations

Synthesis of glycoconjugates during the development of mouse embryosin vitro

1980 • 30 citations

Kallikrein and renin in the membrane fractions of the rat kidney.

1980 • 30 citations

Uncontrolled PGI2 production by whole vessel wall segments due to thrombin generation and its prevention by heparin

1979 • 26 citations

Factors Modulating the Interaction of LDL with an Arterial Lipoprotein Complexing Proteoglycan: The Effect of HDL

1980 • 24 citations

Mechanisms of platelet adhesion to the basal lamina.

1978 • 21 citations

Platelet Interactions with the Endothelium and the Subendothelium: the Role of Thrombin and Prostacyclin

1979 • 21 citations

Biochemical characterization of procollagen-collagen synthesized by rabbit corneal endothelial cells in culture.

1979 • 18 citations

Cell-surface glycosaminoglycans are not released from human diploid fibroblasts by non-enzymatic methods

1979 • 15 citations

Kinins and Angiotensins Angiotensin I Converting Enzyme (Kininase II) in Edothelial Cells Cultured from Human Pulmonary Arteries and Veins

1980 • 12 citations

Sulfated glycoproteins and extracellular matrix of cultured human pulmonary endothelial cells

1981 • 12 citations

A human model for study of blood-vascular wall interactions. Effects of enzymatic treatment of intima.

1981 • 4 citations