Effects of reactive oxygen and nitrogen metabolites on MCP-1-induced monocyte chemotactic activity in vitro

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Peroxynitrite oxidation of sulfhydryls.

1991 • 2,479 citations

Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide

1991 • 2,215 citations

Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

1992 • 1,499 citations

Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide

1992 • 1,319 citations

Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant.

1994 • 1,190 citations

Quantitative Aspects of the Production of Superoxide Anion Radical by Milk Xanthine Oxidase

1970 • 1,037 citations

Monocyte chemoattractant protein-1 in human atheromatous plaques.

1991 • 892 citations

Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions.

1991 • 879 citations

Oxidation of methionyl residues in proteins: Tools, targets, and reversal

1995 • 860 citations

Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts.

1996 • 771 citations

Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line.

1989 • 753 citations

Enhanced production of monocyte chemoattractant protein-1 in rheumatoid arthritis.

1992 • 667 citations

“NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms

1996 • 660 citations

Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants.

1989 • 497 citations

Evidence for In Vivo Peroxynitrite Production in Human Acute Lung Injury

1995 • 491 citations

The Simultaneous Generation of Superoxide and Nitric Oxide Can Initiate Lipid Peroxidation in Human Low Density Lipoprotein

1992 • 460 citations

Effects of peroxynitrite‐induced protein modifications on tyrosine phosphorylation and degradation

1996 • 450 citations

Inactivation of Human Manganese-superoxide Dismutase by Peroxynitrite Is Caused by Exclusive Nitration of Tyrosine 34 to 3-Nitrotyrosine

1998 • 444 citations

Increased formation of the potent oxidant peroxynitrite in the airways of asthmatic patients is associated with induction of nitric oxide synthase: effect of inhaled glucocorticoid

1998 • 441 citations

Inducible nitric oxide synthase is present within human atherosclerotic lesions and promotes the formation and activity of peroxynitrite.

1996 • 410 citations

Rapid quantitation of neutrophil chemotaxis: Use of a polyvinylpyrrolidone-free polycarbonate membrane in a multiwell assembly

1980 • 348 citations

Monocyte chemotactic proteins MCP‐1, MCP‐2, and MCP‐3 are major attractants for human CD4 ⁺ and CD8 ⁺ T lymphocytes

1994 • 322 citations

One- and two-electron oxidations of methionine by peroxynitrite.

1994 • 318 citations

A Novel Reaction Mechanism for the Formation of S-Nitrosothiol in Vivo

1997 • 302 citations

Detection of monocyte chemoattractant protein-1 in human atherosclerotic lesions by an anti-monocyte chemoattractant protein-1 monoclonal antibody

1993 • 272 citations

Nitric Oxide

1995 • 266 citations

Purification of a monocyte chemotactic factor secreted by nonhuman primate vascular cells in culture

1988 • 263 citations

Nitric oxide-mediated mitochondrial damage: A potential neuroprotective role for glutathione

1996 • 263 citations

Peroxynitrite-Dependent Tryptophan Nitration

1996 • 254 citations

Inactivation of .alpha.1-proteinase inhibitor by peroxynitrite

1992 • 253 citations

Nitric Oxide Regulates Monocyte Chemotactic Protein-1

1997 • 221 citations

INTERACTIONS OF THE COMPLEMENT SYSTEM WITH ENDOTOXIC LIPOPOLYSACCHARIDE

1968 • 220 citations

Monocyte chemoattractant protein-1 is sufficient for the chemotaxis of monocytes and lymphocytes in transgenic mice but requires an additional stimulus for inflammatory activation.

1997 • 209 citations

The kinetics of the oxidation of l-ascorbic acid by peroxynitrite

1995 • 188 citations

Enhanced expression and production of monocyte chemoattractant protein-1 in inflammatory bowel disease mucosa

1996 • 163 citations

Structure/activity analysis of human monocyte chemoattractant protein-1 (MCP-1) by mutagenesis. Identification of a mutated protein that inhibits MCP-1-mediated monocyte chemotaxis.

1994 • 158 citations

Monocyte Chemoattractant Protein-1 (MCP-1) in Inflammatory Joint Diseases and Its Involvement in the Cytokine Network of Rheumatoid Synovium

1993 • 133 citations

Nitric Oxide and Some Nitric Oxide Donor Compounds Enhance the Cytotoxicity of Cisplatin

1997 • 129 citations

Desferrioxamine inhibition of the hydroxyl radical-like reactivity of peroxynitrite: Role of the hydroxamic groups

1995 • 123 citations

‘Footprinting’ proteins on DNA with peroxonitrous acid

1993 • 100 citations

Identification of the essential tyrosine residue in the beta subunit of bovine heart mitochondrial F1-ATPase that is modified by 7-chloro-4-nitro[14C]benzofurazan.

1984 • 98 citations

Nitric oxide synthase inhibitors attenuate human monocyte chemotaxis in vitro

1993 • 95 citations

A Mechanistic Analysis of Nitric Oxide-Induced Cellular Toxicity

1997 • 90 citations

Radical releasing properties of nitric oxide donors GEA 3162, SIN-1 and S-nitroso-N-acetylpenicillamine

1998 • 78 citations

The effect of nitric oxide-donating vasodilators on monocyte chemotaxis and intracellular cGMP concentrations in vitro

1993 • 75 citations

Superoxide released from neutrophils causes a reduction in nitric oxide gas

1998 • 71 citations

Pulmonary Vascular Stress from Carbon Monoxide

1999 • 41 citations

Inhibition of peroxynitrite-mediated tyrosine nitration by a novel pyrrolopyrimidine antioxidant

1998 • 29 citations

Mapping of MCP‐1 functional domains by peptide analysis and site‐directed mutagenesis

1998 • 14 citations