Effects of peroxynitrite‐induced protein modifications on tyrosine phosphorylation and degradation

Protein damage and degradation by oxygen radicals. I. general aspects.

1987 • 1,618 citations

Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

1992 • 1,499 citations

Extensive Nitration of Protein Tyrosines in Human Atherosclerosis Detected by Immunohistochemistry

1994 • 1,138 citations

Evidence for nitric oxide‐mediated oxidative damage in chronic inflammation Nitrotyrosine in serum and synovial fluid from rheumatoid patients

1994 • 718 citations

Peroxynitrite‐mediated oxidative protein modifications

1995 • 611 citations

Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury.

1994 • 599 citations

Evidence for In Vivo Peroxynitrite Production in Human Acute Lung Injury

1995 • 491 citations

The insulinomimetic agents H2O2 and vanadate stimulate protein tyrosine phosphorylation in intact cells.

1990 • 440 citations

Inhibition of Neuronal Nitric Oxide Synthase by 7‐Nitroindazole Protects Against MPTP‐Induced Neurotoxicity in Mice

1995 • 416 citations

Aromatic hydroxylation and nitration of phenylalanine and tyrosine by peroxynitrite

1994 • 377 citations

Role of inducible nitric oxide synthase expression and peroxynitrite formation in guinea pig ileitis

1995 • 301 citations

Blockade of neuronal nitric oxide synthase protects against excitotoxicity in vivo

1995 • 283 citations

Inactivation of .alpha.1-proteinase inhibitor by peroxynitrite

1992 • 253 citations

Production of nitric oxide and peroxynitrite in the lung during acute endotoxemia

1994 • 250 citations

Endotoxin triggers the expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in the rat aorta in vivo

1995 • 235 citations

Peroxynitrite‐mediated oxidation of albumin to the protein‐thiyl free radical

1994 • 146 citations

Chemical influences on the specificity of tyrosine phosphorylation.

1990 • 101 citations

Peroxynitrite‐Mediated Inhibition of DOPA Synthesis in PC12 Cells

1995 • 79 citations

Nitration of tyrosyl-residues from extra- and intracellular proteins in human whole blood

1995 • 68 citations

Stimulation of tyrosine-specific protein phosphorylation in the rat liver plasma membrane by oxygen radicals

1986 • 57 citations

Inducible nitric oxide synthase and guinea‐pig ileitis induced by adjuvant

1995 • 31 citations