Strategies for immune intervention in visceral leishmaniasis

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

1995 • 1,695 citations

The B7 and CD28 receptor families

1994 • 1,342 citations

Natural resistance to infection with intracellular parasites: Isolation of a candidate for Bcg

1993 • 1,107 citations

Immunology of Leishmaniasis

1993 • 337 citations

An analysis of T cell responsiveness in Indian kala-azar.

1987 • 253 citations

Differential production of Th1- and Th2-derived cytokines does not determine the genetically controlled or vaccine-induced rate of cure in murine visceral leishmaniasis.

1991 • 231 citations

T-cell and cytokine responses in leishmaniasis

1993 • 221 citations

T _H 1 and T _H 2 Cell Antigen Receptors in Experimental Leishmaniasis

1993 • 204 citations

Antigen Analogs/MHC Complexes as Specific T Cell Receptor Antagonists

1994 • 195 citations

Th1 and Th2 cell-associated cytokines in experimental visceral leishmaniasis

1994 • 181 citations

Altered cell signaling and mononuclear phagocyte deactivation during intracellular infection

1994 • 174 citations

Role and effect of TNF-alpha in experimental visceral leishmaniasis.

1994 • 141 citations

Role of inorganic nitrogen oxides and tumor necrosis factor alpha in killing Leishmania donovani amastigotes in gamma interferon-lipopolysaccharide-activated macrophages from Lshs and Lshr congenic mouse strains

1991 • 139 citations

Immunochemotherapy for Intracellular Leishmania donovani Infection: Interferon Plus Pentavalent Antimony

1988 • 131 citations

Glycoinositolphospholipids ofLeishmania major inhibit nitric oxide synthesis and reduce leishmanicidal activity in murine macrophages

1995 • 128 citations

Interleukin 12 is effective treatment for an established systemic intracellular infection: experimental visceral leishmaniasis.

1995 • 126 citations

Distinct signal transduction in mouse CD4+ and CD8+ splenic T cells after CD28 receptor ligation.

1995 • 125 citations

Requirement for T cells and effect of lymphokines in successful chemotherapy for an intracellular infection. Experimental visceral leishmaniasis.

1989 • 125 citations

Deficient expression of co‐stimulatory molecules on Leishmania‐infected macrophages

1994 • 123 citations

Role and effect of IL-2 in experimental visceral leishmaniasis.

1993 • 109 citations

NH2-terminal sequence of macrophage-expressed natural resistance-associated macrophage protein (Nramp) encodes a proline/serine-rich putative Src homology 3-binding domain.

1994 • 93 citations

Effect of granulocyte-macrophage colony-stimulating factor in experimental visceral leishmaniasis.

1995 • 87 citations

The macrophage resistance gene Lsh/Ity/Bcg

1989 • 82 citations

T cell and non-T cell compartments can independently determine resistance to Leishmania major.

1995 • 80 citations

Immunochemotherapy for a Systemic Intracellular Infection: Accelerated Response Using Interferon- in Visceral Leishmaniasis

1995 • 80 citations

Leishmania donovani infection in scid mice: lack of tissue response and in vivo macrophage activation correlates with failure to trigger natural killer cell-derived gamma interferon production in vitro

1992 • 79 citations

Comparison of T-cell responses in self-limiting versus progressive visceral Leishmania donovani infections in golden hamsters

1989 • 71 citations

Leishmania donovani infection in heterozygous and recombinant H-2 haplotype mice

1983 • 62 citations

Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor Reverses Neutropenia and Reduces Secondary Infections in Visceral Leishmaniasis

1994 • 58 citations

A reverse transcription-polymerase chain reaction technique to detect feline cytokine genes

1995 • 57 citations

Acquisition of cell-mediated immunity to Leishmania. II. LSH gene regulation of accessory cell function.

1988 • 35 citations

Visceral Leishmaniasis in Ververt Monkeys: Immunological Responses During Asymptomatic Infections

1995 • 33 citations

Recombinant interleukin-1 alpha augments granuloma formation and cytokine production but not parasite clearance in mice infected with Leishmania donovani

1992 • 24 citations

Leishmania donovani: Acquired resistance to visceral leishmaniasis in the golden hamster

1976 • 21 citations

Visceral leishmaniasis in the BALB/c mouse: sodium stibogluconate treatment during acute and chronic stages of infection: II. Changes in tissue drug distribution

1992 • 10 citations