Inclusion-Body Myositis: Newest Concepts of Pathogenesis and Relation to Aging and Alzheimer Disease

AP-1 function and regulation

1997 • 2,833 citations

The cell biology of β-amyloid precursor protein and presenilin in Alzheimer's disease

1998 • 845 citations

Advanced Maillard reaction end products are associated with Alzheimer disease pathology.

1994 • 712 citations

New insights into the regulation of protein kinase C and novel phorbol ester receptors

1999 • 600 citations

Rapid examination of muscle tissue

1963 • 582 citations

INCLUSION BODY MYOSITIS

1989 • 570 citations

RNA stimulates aggregation of microtubule‐associated protein tau into Alzheimer‐like paired helical filaments

1996 • 502 citations

Isolation of Low‐Molecular‐Weight Proteins from Amyloid Plaque Fibers in Alzheimer's Disease

1986 • 443 citations

Microtubule-associated Protein/Microtubule Affinity-regulating Kinase (p110mark)

1995 • 361 citations

Human prion diseases

1994 • 325 citations

The Pathogenesis of Alzheimer Disease: An Alternative to the Amyloid Hypothesis

1996 • 288 citations

Neuropathology of synuclein aggregates

2000 • 260 citations

Alzheimer's disease: a re-examination of the amyloid hypothesis

1998 • 256 citations

Inclusion body myositis

2011 • 220 citations

The Alzheimer family of diseases: Many etiologies, one pathogenesis?

1997 • 218 citations

Serum cholesterol, APOE genotype, and the risk of Alzheimer’s disease: A population-based study of African Americans

2000 • 209 citations

Amyloid Filaments in Inclusion Body Myositis

1991 • 205 citations

Recognition of tau epitopes by anti-neurofilament antibodies that bind to Alzheimer neurofibrillary tangles.

1987 • 181 citations

Myofibrillar Myopathy with Abnormal Foci of Desmin Positivity.

1996 • 159 citations

The molecular and genetic basis of AD: The end of the beginning

2000 • 157 citations

The Molecular Chaperone αB-crystallin Enhances Amyloid β Neurotoxicity

1999 • 157 citations

The Genetics of the Amyloidoses

2000 • 150 citations

Light and electron microscopic localization of beta-amyloid protein in muscle biopsies of patients with inclusion-body myositis.

1992 • 149 citations

β‐Amyloid precursor epitopes in muscle fibers of inclusion body myositis

1993 • 140 citations

B-Crystallin immunolocalization yields new insights into inclusion body myositis

2000 • 129 citations

Twisted tubulofilaments of inclusion body myositis muscle resemble paired helical filaments of Alzheimer brain and contain hyperphosphorylated tau.

1994 • 128 citations

Tau as a marker for Alzheimer's disease

1993 • 127 citations

Sporadic inclusion-body myositis and hereditary inclusion-body myopathies: current concepts of diagnosis and pathogenesis

1998 • 117 citations

Enhanced detection of Congo‐red‐positive amyloid deposits in muscle fibers of inclusion body myositis and brain of Alzheimer's disease using fluorescence technique

1993 • 111 citations

Difference in Expression of Phosphorylated Tau Epitopes between Sporadic Inclusion-body Myositis and Hereditary Inclusion-body Myopathies

1996 • 107 citations

A direct role for protein kinase C and the transcription factor Jun/AP-1 in the regulation of the Alzheimer's beta-amyloid precursor protein gene.

1994 • 105 citations

Novel Immunolocalization of α-Synuclein in Human Muscle of Inclusion-Body Myositis, Regenerating and Necrotic Muscle Fibers, and at Neuromuscular Junctions

2000 • 93 citations

β-amyloid precursor protein mRNA is increased in inclusion-body myositis muscle

1993 • 88 citations

Amyloid-β Deposition in Skeletal Muscle of Transgenic Mice

1998 • 88 citations

New advances in inclusion-body myositis

1993 • 80 citations

Sporadic Inclusion-Body Myositis and Hereditary Inclusion-Body Myopathies

1998 • 68 citations

α2 Macroglobulin and the risk of Alzheimer’s disease

2000 • 66 citations

Transgenic Mice Over-Expressing the C-99 Fragment of βPP with an α-Secretase Site Mutation Develop a Myopathy Similar to Human Inclusion Body Myositis

1998 • 66 citations

Prion protein is abnormally accumulated in inclusion-body myositis

1993 • 61 citations

Relative abundance of tau and neurofilament epitopes in hippocampal neurofibrillary tangles.

1990 • 60 citations

Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer’s disease?

2000 • 60 citations

Use of anti‐neurofilament antibody to identify paired‐helical filaments in inclusion‐body myositis

1996 • 57 citations

Immunocytochemical localization of ubiquitin in inclusion body myositis allows its light‐microscopic distinction from polymyositis

1992 • 56 citations

Expression of human IAP-like protein in skeletal muscle: a possible explanation for the rare incidence of muscle fiber apoptosis in T-cell mediated inflammatory myopathies

2000 • 56 citations

Light and electron microscopic immunolocalization of presenilin 1 in abnormal muscle fibers of patients with sporadic inclusion-body myositis and autosomal-recessive inclusion-body myopathy.

1998 • 55 citations

Sporadic Inclusion Body Myositis Correlates with Increased Expression and Cross-linking by Transglutaminases 1 and 2

2000 • 55 citations

Abnormal accumulation of prion protein mRNA in muscle fibers of patients with sporadic inclusion-body myositis and hereditary inclusion-body myopathy.

1994 • 54 citations

Immunolocalization of transcription factor NF-κB in inclusion-body myositis muscle and at normal human neuromuscular junctions

1998 • 50 citations

Impaired innervation of cultured human muscle overexpressing βAPP experimentally and genetically

1998 • 48 citations

Inclusion body myositis

1999 • 47 citations

Prion protein is strongly immunolocalized at the postsynaptic domain of human normal neuromuscular junctions

1993 • 46 citations

Apolipoprotein E and apolipoprotein E messenger RNA in muscle of inclusion body myositis and myopathies

1996 • 44 citations

Association of Active Extracellular Signal-Regulated Protein Kinase with Paired Helical Filaments of Inclusion-Body Myositis Muscle Suggests Its Role in Inclusion-Body Myositis Tau Phosphorylation

2000 • 40 citations

Ubiquitin immunostaining and inclusion body myositis: Study of 30 patients with inclusion body myositis

1997 • 39 citations

Fourteen Newly Recognized Proteins at the Human Neuromuscular Junctions‐and Their Nonjunctional Accumulation in Inclusion‐Body Myositisa^a

1998 • 35 citations

Inclusion body myositis, muscle blood vessel and cardiac amyloidosis, and transthyretin Val122Ile allele

2000 • 33 citations

Paired Helical Filaments of Inclusion-Body Myositis Muscle Contain RNA and Survival Motor Neuron Protein

2000 • 29 citations

Mapping of a candidate region for susceptibility to inclusion body myositis in the human major histocompatibility complex

1999 • 28 citations

Redox factor-1 in muscle biopsies of patients with inclusion-body myositis

2000 • 28 citations

Cyclin-dependent kinase 5 colocalizes with phosphorylated tau in human inclusion-body myositis paired-helical filaments and may play a role in tau phosphorylation

2000 • 22 citations

Aberrant expression of cyclin-dependent kinase 5 in inclusion body myositis

1999 • 22 citations

Sporadic Inclusion Body Myositis and Hereditary Inclusion Body Myopathy

2002 • 21 citations

Inclusion body myositis

2000 • 19 citations

The muscle mitogen-activated protein kinase is altered in sporadic inclusion body myositis

2000 • 14 citations