The pH-dependence of class B and class C β-lactamases

Data Reduction and Error Analysis for the Physical Sciences.

1972 • 3,710 citations

The structure of β-lactamases

1980 • 1,705 citations

ampC cephalosporinase of Escherichia coli K-12 has a different evolutionary origin from that of beta-lactamases of the penicillinase type.

1981 • 384 citations

Determining the Chemical Mechanisms of Enzyme‐Catalyzed Reactions by Kinetic Studies

1977 • 340 citations

A spectrophotometric assay of β-lactamase action on penicillins

1974 • 266 citations

A simple test for inactivation of an enzyme during assay

1965 • 251 citations

Purification and properties of inducible penicillin beta-lactamase isolated from Pseudomonas maltophilia

1982 • 234 citations

Cephalosporinase and penicillinase activities of a β-lactamase from Pseudomonas pyocyanea

1965 • 195 citations

Estimation of Michaelis constant and maximum velocity from the direct linear plot

1978 • 190 citations

The Chemical Kinetics of Enzyme Action

1976 • 125 citations

Separation, purification and properties of β-lactamase I and β-lactamase II from Bacillus cereus 569/H/9

1974 • 113 citations

Metal cofactor requirement of β-lactamase II

1974 • 111 citations

Resistance of Escherichia coli to Penicillins VI. Purification and Characterization of the Chromosomally Mediated Penicillinase Present in ampA -Containing Strains

1970 • 106 citations

The acyl-enzyme mechanism of β-lactamase action. The evidence for class C β-lactamases

1982 • 96 citations

pH, isotope, and substituent effects on the interconversion of aromatic substrates catalyzed by hydroxybutyrimidylated liver alcohol dehydrogenase

1977 • 90 citations

Active sites of β-lactamases. The chromosomal β-lactamases of Pseudomonas aeruginosa and Escherichia coli

1982 • 72 citations

Histidine residues of zinc ligands in β-lactamase II

1978 • 66 citations

PH-dependence of the steady-state rate of a two-step enzymic reaction

1976 • 53 citations

Half-time analysis of the integrated Michaelis equation. Simulation and use of the half-time plot and its direct linear variant in the analysis of some α-chymotrypsin-, papain- and fumarase-catalysed reactions

1982 • 52 citations

The pH-dependence and group modification of β-lactamase I

1975 • 51 citations

An easy method for the determination of initial rates

1981 • 48 citations

A spectroscopic study of metal ion and ligand binding to β-lactamase II

1980 • 37 citations

Mutant of Pseudomonas aeruginosa 18S That Synthesizes Type Id β-Lactamase Constitutively

1976 • 28 citations

Isolation and Properties of an Inducible and a Constitutive ss- Lactamase from Pseudomonas aeruginosa

1982 • 27 citations

Production of a variant of β-lactamase II with selectively decreased cephalosporinase activity by a mutant of Bacillus cereus 569/H/9

1980 • 26 citations

Active sites of β-lactamases from Bacillus cereus

1980 • 21 citations

The 1H nuclear-magnetic-resonance spectroscopy of cobalt(II)-β-lactamase II

1980 • 18 citations

Use of the pH-Stat in Kinetic Studies of Reactions Whose Products Are Capable of Functioning as Buffers^*

1962 • 17 citations

Kinetic parameters from progress curves of competing substrates. Application to β-lactamases

1983 • 10 citations