Memory CD4+ T cells in man form two distinct subpopulations, defined by their expression of isoforms of the leucocyte common antigen, CD45.

Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies.

1987 • 1,060 citations

Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.

1988 • 930 citations

Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production.

1988 • 917 citations

The Leukocyte Common Antigen Family

1989 • 741 citations

Simultaneous production of IL-2, IL-4, and IFN-gamma by activated human CD4+ and CD8+ T cell clones.

1988 • 509 citations

Antiproliferative effect of IFN-gamma in immune regulation. III. Differential selection of TH1 and TH2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-gamma.

1989 • 349 citations

Molecular and antigenic heterogeneity of the rat leukocyte‐common antigen from thymocytes and T and B lymphocytes

1985 • 286 citations

MRC OX-22, a monoclonal antibody that labels a new subset of T lymphocytes and reacts with the high molecular weight form of the leukocyte-common antigen.

1983 • 243 citations

Structural variants of human T200 glycoprotein (leukocyte-common antigen).

1987 • 239 citations

A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines

1989 • 237 citations

T cells that help B cell responses to soluble antigen are distinguishable from those producing interleukin 2 on mitogenic or allogeneic stimulation.

1986 • 218 citations

Profiles of lymphokine activities and helper function for IgE in human T cell clones

1988 • 204 citations

Lymphocyte specific heterogeneity in the rat leucocyte common antigen (T200) is due to differences in polypeptide sequences near the NH2-terminus.

1987 • 159 citations

Human lymphocyte differentiation antigens HB-10 and HB-11. II. Differential production of B cell growth and differentiation factors by distinct helper T cell subpopulations.

1985 • 145 citations

Restricted production of interleukin 4 by activated human T cells.

1988 • 141 citations

Characterization of CD45 and CD45R monoclonal antibodies using transfected mouse cell lines that express individual human leukocyte common antigens.

1988 • 140 citations

The monoclonal antibody, UCHL1, recognizes a 180,000 MW component of the human leucocyte-common antigen, CD45.

1988 • 130 citations

Phenotypic changes associated with activation of CD45RA+ and CD45RO+ T cells.

1990 • 127 citations

The MRC OX-22- CD4+ T cells that help B cells in secondary immune responses derive from naive precursors with the MRC OX-22+ CD4+ phenotype.

1989 • 125 citations

Comparative biochemical and tissue distribution study of four distinct CD45 antigen specificities.

1988 • 96 citations

Two subsets of human CD4⁺T helper cells differing in kinetics and capacities to produce interleukin 2 and interferon‐γ can be defined by the Leu‐18 and UCHLl monoclonal antibodies

1988 • 94 citations

Human T cell subsets

1987 • 85 citations

Isolation of encephalitogenic CD4+ T cell clones in the rat

1989 • 78 citations

Lymphocyte cell surface glycoproteins which bind to soybean and peanut lectins.

1982 • 75 citations

Sequences of Ly-5 cDNA: isoform-related diversity of Ly-5 mRNA.

1986 • 74 citations

Activation of rat T lymphocytes by anti-CD2 monoclonal antibodies.

1988 • 67 citations

Immunoregulatory T lymphocytes in man. Soluble antigen-specific suppressor-inducer T lymphocytes are derived from the CD4+CD45R-p80+ subpopulation.

1987 • 66 citations

Subsets of Rat CD4+ T Cells Defined by Their Differential Expression of Variants of the CD45 Antigen: Developmental Relationships and In Vitro and In Vivo Functions

1990 • 54 citations

Identification of the sequence required for expression of the 2H4 epitope on the human leukocyte common antigens.

1987 • 51 citations

Identification and isolation of OKT4+ suppressor cells with the monoclonal antibody WR16.

1986 • 43 citations