Antibodies against Phospholipids other than Cardiolipin: Potential Roles for Both Phospholipid and Protein

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages.

1992 • 3,279 citations

Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H).

1990 • 1,618 citations

Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor

1990 • 1,294 citations

Lipid Asymmetry in Membranes

1979 • 1,245 citations

Lupus Anticoagulant IgG's (LA) Are Not Directed to Phospholipids only, but to a Complex of Lipid-Bound Human Prothrombin

1991 • 583 citations

Thrombosis, Recurrent Fetal Loss, and Thrombocytopenia

1986 • 554 citations

Changes in membrane phospholipid distribution during platelet activation

1983 • 551 citations

Antiphospholipid antibodies directed against a combination of phospholipids with prothrombin, protein C, or protein S: an explanation for their pathogenic mechanism? [see comments]

1993 • 496 citations

Immunology and Clinical Importance of Antiphospholipid Antibodies

1991 • 490 citations

Binding of annexin V/placental anticoagulant protein I to platelets. Evidence for phosphatidylserine exposure in the procoagulant response of activated platelets.

1990 • 372 citations

In vivo recognition and clearance of red blood cells containing phosphatidylserine in their plasma membranes.

1985 • 352 citations

Annexin V as a probe of aminophospholipid exposure and platelet membrane vesiculation: a flow cytometry study showing a role for free sulfhydryl groups

1993 • 348 citations

"Anticardiolipin" autoantibodies recognize beta 2-glycoprotein I in the absence of phospholipid. Importance of Ag density and bivalent binding.

1995 • 337 citations

Autoantibodies to phospholipid-binding plasma proteins: a new view of lupus anticoagulants and other "antiphospholipid" autoantibodies [see comments]

1994 • 317 citations

Anti-prothrombin antibodies and the lupus anticoagulant

1988 • 255 citations

The Relationship Between Lupus Anticoagulants and Antibodies to Phospholipid

1988 • 254 citations

β2-glycoprotein-I (apolipoprotein H) interactions with phospholipid vesicles

1984 • 234 citations

Development of an ELISA for Autoantibodies to Prothrombin Showing their Prevalence in Patients with Lupus Anticoagulants

1995 • 215 citations

Anti-phospholipid autoantibodies bind to apoptotic, but not viable, thymocytes in a beta 2-glycoprotein I-dependent manner.

1996 • 210 citations

Differentiation-dependent expression of phosphatidylserine in mammalian plasma membranes: quantitative assessment of outer-leaflet lipid by prothrombinase complex formation.

1989 • 186 citations

Anticoagulant Activity of β2-Glycoprotein I Is Potentiated by a Distinct Subgroup of Anticardiolipin Antibodies

1992 • 183 citations

Collagen-induced exposure of anionic phospholipid in platelets and platelet-derived microparticles.

1991 • 168 citations

Phospholipid binding of annexin V: Effects of calcium and membrane phosphatidylserine content

1992 • 154 citations

Beta 2-glycoprotein I is a requirement for anticardiolipin antibodies binding to activated platelets: differences with lupus anticoagulants

1993 • 151 citations

Increased adherence of sickled and phosphatidylserine-enriched human erythrocytes to cultured human peripheral blood monocytes.

1985 • 151 citations

Anti‐annexin V antibody in systemic lupus erythematosus patients with lupus anticoagulant and/or anticardiolipin antibody

1994 • 145 citations

Particle digestibility is required for induction of the phosphatidylserine recognition mechanism used by murine macrophages to phagocytose apoptotic cells.

1993 • 140 citations

Human hybridoma lupus anticoagulants distinguish between lamellar and hexagonal phase lipid systems.

1986 • 121 citations

Autoantibodies to phosphatidylethanolamine (PE) recognize a kininogen- PE complex

1995 • 118 citations

Distinguishing Plasma Lupus Anticoagulants from Anti-Factor Antibodies Using Hexagonal (II) Phase Phospholipids

1989 • 111 citations

Studies of IgG, IgM and IgA antiphospholipid antibody isotypes in systemic lupus erythematosus.

1988 • 103 citations

Association of lupus anticoagulant with antibody against phosphatidylserine

1987 • 94 citations

Abnormal prothrombin crossed-immunoelectrophoresis in patients with lupus inhibitors

1984 • 90 citations

Antiphospholipid antibodies in systemic lupus erythematosus: evidence of an association with positive Coombs' and hypocomplementemia.

1988 • 82 citations

Phospholipid binding of antiphospholipid antibodies and placental anticoagulant protein

1992 • 81 citations

Erythrocyte Membrane Lipids and Rh Antigen Activity

1972 • 80 citations

Exposure of Anionic Phospholipids upon Platelet Activation Permits Binding of β2 Glycoprotein I and Through it that ofIgG Antiphospholipid Antibodies. Studies in Platelets from Patients with Antiphospholipid Syndrome and Normal Subjects

1994 • 78 citations

Antibody to phosphatidylethanolamine in a patient with lupus anticoagulant and thrombosis.

1989 • 75 citations

Lupus Anticoagulant Autoantibody Induces Apoptosis in Umbilical Vein Endothelial Cells: Involvement of Annexin V

1994 • 72 citations

The thrombotic diathesis associated with the presence of phospholipid antibodies may be due to low levels of free protein S

1992 • 70 citations

Hemolytic anemia related to an IgM autoantibody to phosphatidylcholine that binds In vitro to stored and to bromelain-treated human erythrocytes

1990 • 68 citations

Antiphosphatidylethanolamine antibody as the sole antiphospholipid antibody in systemic lupus erythematosus with thrombosis.

1992 • 60 citations

Interactions and molecular structure of cardiolipin and β2-glycoprotein 1 (β2-GP1)

1995 • 46 citations

Phospholipid-Specific Conformational Changes in Human Prothrombin upon Binding to Procoagulant Acidic Lipid Membranes

1994 • 46 citations

Antiphosphatidylethanolamine Antibodies in Systemic Lupus Erythematosus

1993 • 42 citations

Immunologic Detection of Phosphatidylserine Externalization during Thrombin-Induced Platelet Activation

1993 • 40 citations

Presence of serum antibodies to coagulation protein C in patients with systemic lupus erythematosus is not associated with antigenic or functional protein c deficiencies

1993 • 29 citations

The nature of antiphospholipid antibodies.

1992 • 29 citations

Autoimmune Haemolytic Anaemia due to Anti‐Phospholipid Antibodies

1991 • 26 citations

Evaluation of the clinical and laboratory associations of antiphosphatidylethanolamine antibodies

1990 • 24 citations

Reactivity patterns of anti-phospholipid antibodies in systemic lupus erythematosus sera in relation to erythrocyte binding and complement activation.

1991 • 24 citations

Antibodies to Phosphatidylethanolamine in Antiphospholipid Syndrome and Systemic Lupus Erythematosus: Their Correlation with Anticardiolipin Antibodies and P₂Glycoprotein-I Plasma Levels

1993 • 24 citations

The phospholipid requirement for RH0(D) antigen activity: Mode of inactivation by phospholipases and of protection by anti-Rh0(D) antibody

1984 • 17 citations

Regulation of Phospholipid Asymmetry and Induction of Antiphospholipid Antibodies

1995 • 13 citations

Heterogeneity and Diversity of IgM and IgG Lupus Anticoagulants in an Individual with Systemic Lupus Erythematosus

1994 • 11 citations