Antiphospholipid antibodies directed against a combination of phospholipids with prothrombin, protein C, or protein S: an explanation for their pathogenic mechanism? [see comments]

The 1982 revised criteria for the classification of systemic lupus erythematosus

1982 • 14,553 citations

Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA

1973 • 6,904 citations

Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H).

1990 • 1,618 citations

ANTICARDIOLIPIN ANTIBODIES: DETECTION BY RADIOIMMUNOASSAY AND ASSOCIATION WITH THROMBOSIS IN SYSTEMIC LUPUS ERYTHEMATOSUS

1983 • 1,413 citations

Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor

1990 • 1,294 citations

Deficiency of protein C in congenital thrombotic disease.

1981 • 1,260 citations

Familial protein S deficiency is associated with recurrent thrombosis.

1984 • 614 citations

Lupus Anticoagulant IgG's (LA) Are Not Directed to Phospholipids only, but to a Complex of Lipid-Bound Human Prothrombin

1991 • 583 citations

Plasma protein S deficiency in familial thrombotic disease

1984 • 516 citations

Properties of the factor Xa binding site on human platelets.

1978 • 443 citations

The Second International Anti-Cardiolipin Standardization Workshop/The Kingston Anti-Phospholipid Antibody Study (KAPS) Group

1990 • 420 citations

Monoclonal immunoglobulin M lambda coagulation inhibitor with phospholipid specificity. Mechanism of a lupus anticoagulant.

1980 • 367 citations

Serial propagation of human endothelial cells in vitro.

1981 • 348 citations

Inactivation of human factor VIII by activated protein C. Cofactor activity of protein S and protective effect of von Willebrand factor.

1988 • 244 citations

Inhibition of activated protein C and its cofactor protein S by antiphospholipid antibodies

1990 • 216 citations

Lupus Anticoagulants and Thrombosis

1985 • 197 citations

Effect of Lupus Anticoagulant on Antithrombogenic Properties of Endothelial Cells - Inhibition of Thrombomodulin-Dependent Protein C Activation

1988 • 194 citations

Immunological specificity and mechanism of action of IgG lupus anticoagulants

1987 • 193 citations

Purification and characterization of human coagulation factor V.

1981 • 187 citations

Impaired catalytic function of activated protein C: a new in vitro manifestation of lupus anticoagulant

1989 • 178 citations

Lupus anticoagulant activity is frequently dependent on the presence of beta 2-glycoprotein I.

1992 • 175 citations

Media conditioned by cultured human vascular endothelial cells inhibit the growth of vascular smooth muscle cells

1982 • 149 citations

Coagulation screen is more specific than the anticardiolipin antibody ELISA in defining a thrombotic subset of lupus patients.

1988 • 141 citations

An IgM Lupus Anticoagulant that Neutralizes the Enhancing Effect of Phospholipid on Purified Endothelial Thrombomodulin Activity-A Mechanism for Thrombosis

1986 • 130 citations

Distinguishing Plasma Lupus Anticoagulants from Anti-Factor Antibodies Using Hexagonal (II) Phase Phospholipids

1989 • 111 citations

Phospholipid in the hexagonal II phase is immunogenic: evidence for immunorecognition of nonbilayer lipid phases in vivo.

1990 • 93 citations

Isolation of human blood coagulation α-factor Xa by soybean trypsin inhibitor-Sepharose chromatography and its active-site titration with fluorescein mono-p-guanidinobenzoate

1989 • 85 citations

Thrombosis Associated with Antiphospholipid Antibodies Cannot Be Explained by Effects on Endothelial and Platelet Prostanoid Synthesis

1988 • 82 citations

Lupus anticoagulant: revival of an old phenomenon.

1985 • 76 citations

Impaired Fibrinolysis as an Essential Contribution to Thrombosis in Patients with Lupus Anticoagulant

1989 • 73 citations

In Vitro Studies of Antiphospholipid Antibodies and Its Cofactor, β2-Glycoprotein I, Show Negligible Effects on Endothelial Cell Mediated Protein C Activation

1991 • 46 citations

Endothelial-Dependent Fibrinolysis in Subjects with the Lupus Anticoagulant and Thrombosis

1988 • 44 citations

Inhibition of human blood coagulation factor Xa by .alpha.2-macroglobulin

1987 • 33 citations

Inhibition of phospholipid and platelet‐dependent prothrombinase activity in the plasma of patients with lupus anticoagulants

1989 • 31 citations

The antiphospholipid antibody dilemma

1990 • 7 citations