Superoxide generation in transformed B-lymphocytes from patients with severe, malignant osteopetrosis.

Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells.

1990 • 1,028 citations

Mouse model of X–linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production

1995 • 920 citations

Cloning the gene for an inherited human disorder—chronic granulomatous disease—on the basis of its chromosomal location

1986 • 839 citations

Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo.

1990 • 827 citations

The biochemical basis of the NADPH oxidase of phagocytes

1993 • 631 citations

Studies on the inhibitory mechanism of iodonium compounds with special reference to neutrophil NADPH oxidase

1993 • 586 citations

The superoxide‐generating oxidase of phagocytic cells

1991 • 564 citations

The Nonamer UUAUUUAUU Is the Key AU-Rich Sequence Motif That Mediates mRNA Degradation

1995 • 524 citations

The p47phox mouse knock-out model of chronic granulomatous disease.

1995 • 487 citations

Cloning of a 67-kD Neutrophil Oxidase Factor with Similarity to a Noncatalytic Region of p60 ^c-src

1990 • 393 citations

[45] Measurement of O2− production by human neutrophils. The preparation and assay of NADPH oxidase-containing particles from human neutrophils

1984 • 359 citations

Recombinant 47-Kilodalton Cytosol Factor Restores NADPH Oxidase in Chronic Granulomatous Disease

1989 • 341 citations

Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b.

1988 • 317 citations

Partial Correction of the Phagocyte Defect in Patients with X-Linked Chronic Granulomatous Disease by Subcutaneous Interferon Gamma

1988 • 264 citations

Phosphorylation of neutrophil 47-kDa cytosolic oxidase factor. Translocation to membrane is associated with distinct phosphorylation events.

1990 • 248 citations

Neutrophil priming: the cellular signals that say ‘amber’ but not ‘green’

1995 • 240 citations

NADPH-oxidase expression and in situ production of superoxide by osteoclasts actively resorbing bone.

1994 • 174 citations

Recent developments in the understanding of the pathophysiology of osteopetrosis

1996 • 143 citations

Superoxide-dependent nitroblue tetrazolium reduction and expression of cytochrome b-245 components by human tonsillar B lymphocytes and B cell lines.

1989 • 140 citations

Superoxide and bone resorption

1994 • 133 citations

Characterization of neutrophil NADPH oxidase factors p47-phox and p67-phox from recombinant baculoviruses.

1991 • 124 citations

Oxygen derived free radicals in osteoclasts: The specificity and location of the nitroblue tetrazolium reaction

1990 • 118 citations

The superoxide generating system of B cell lines. Structural homology with the phagocytic oxidase and triggering via surface Ig.

1988 • 100 citations

Osteoclastic superoxide production and bone resorption: Stimulation and inhibition by modulators of NADPH oxidase

1996 • 89 citations

The Origin of the Osteoclast

1979 • 78 citations

Purification and characterization of a third cytosolic component of the superoxide-generating NADPH oxidase of macrophages.

1991 • 78 citations

Osteopetrosis--multiple pathways for the interception of osteoclast function.

1987 • 74 citations

Nitroblue tetrazolium reduction and bone resorption by osteoclasts in vitro inhibited by a manganese-based superoxide dismutase mimic

1992 • 73 citations

Experimental studies of osteopetrosis in laboratory animals.

1993 • 62 citations

Host Defense in Infantile Osteopetrosis

1979 • 62 citations

Restoration of superoxide generation to a chronic granulomatous disease- derived B-cell line by retrovirus mediated gene transfer

1992 • 57 citations

Neutrophil defect associated with malignant infantile osteopetrosis.

1986 • 55 citations

The heterogeneity of the osteopetroses reflects the diversity of cellular influences during skeletal development

1995 • 48 citations

The 47-kDa protein involved in the NADPH:O2 oxidoreductase activity of human neutrophils is phosphorylated by cyclic AMP-dependent protein kinase without induction of a respiratory burst

1988 • 36 citations

Osteopetrosis

1993 • 31 citations

CD31 (PECAM-1), CDw32 (Fc gamma RII), and anti-HLA class I monoclonal antibodies recognize phosphotyrosine-containing proteins on the surface of human neutrophils.

1994 • 21 citations

Osteoclast radicals

1994 • 19 citations

Establishment of Lymphoblastoid Cell Lines

2003 • 7 citations

Characterization of M-CSF and its receptor in microphthalmic mice.

1995 • 5 citations

Deleted Work

1955 • 0 citations