Inhibition of Sickle Erythrocyte Adhesion to Immobilized Thrombospondin by von Willebrand Factor Under Dynamic Flow Conditions

Synthesis of Antihemophilic Factor Antigen by Cultured Human Endothelial Cells

1973 • 1,303 citations

Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1.

1995 • 673 citations

The structure of human thrombospondin, an adhesive glycoprotein with multiple calcium-binding sites and homologies with several different proteins.

1986 • 575 citations

The complex multimeric composition of factor VIII/von Willebrand factor

1981 • 572 citations

Erythrocyte Adherence to Endothelium in Sickle-Cell Anemia

1980 • 524 citations

Inducible secretion of large, biologically potent von Willebrand factor multimers

1986 • 459 citations

Abnormal Adherence of Sickle Erythrocytes to Cultured Vascular Endothelium

1980 • 423 citations

Synthesis of Factor VIII Antigen by Cultured Guinea Pig Megakaryocytes

1977 • 390 citations

Microvascular sites and characteristics of sickle cell adhesion to vascular endothelium in shear flow conditions: pathophysiological implications.

1989 • 337 citations

Synthesis and secretion of thrombospondin by cultured human endothelial cells.

1982 • 311 citations

Thrombin‐induced increase in albumin permeability across the endothelium

1986 • 307 citations

Isolation and Properties of a Thrombin-sensitive Protein of Human Platelets

1972 • 306 citations

Alpha 4 beta 1-integrin expression on sickle reticulocytes: vascular cell adhesion molecule-1-dependent binding to endothelium

1993 • 283 citations

Changes in cytosolic Ca2+ associated with von Willebrand factor release in human endothelial cells exposed to histamine. Study of microcarrier cell monolayers using the fluorescent probe indo-1.

1987 • 225 citations

The structure of human platelet thrombospondin.

1985 • 222 citations

von Willebrand factor is an acute phase reactant in man

1989 • 221 citations

Cerebrovascular disease in sickle cell anemia: a clinical, pathological and radiological correlation.

1978 • 216 citations

Interactions of thrombospondin with extracellular matrix proteins: selective binding to type V collagen.

1984 • 202 citations

Thrombospondin from activated platelets promotes sickle erythrocyte adherence to human microvascular endothelium under physiologic flow: a potential role for platelet activation in sickle cell vaso-occlusion

1993 • 196 citations

Complex formation of platelet thrombospondin with fibrinogen.

1982 • 195 citations

Sickle reticulocytes adhere to VCAM-1

1995 • 194 citations

von Willebrand factor.

1991 • 192 citations

Thrombospondin mediates adherence of CD36+ sickle reticulocytes to endothelial cells

1992 • 187 citations

von Willebrand Factor: Structure and Function

1993 • 178 citations

Thrombin-mediated release of factor VIII antigen from human umbilical vein endothelial cells in culture

1982 • 178 citations

Analysis of platelet adhesion with a radioactive chemical crosslinking reagent: Interaction of thrombospondin with fibronectin and collagen

1982 • 177 citations

Composition of the von Willebrand factor storage organelle (Weibel-Palade body) isolated from cultured human umbilical vein endothelial cells.

1987 • 176 citations

Unusually large von Willebrand factor multimers increase adhesion of sickle erythrocytes to human endothelial cells under controlled flow.

1987 • 169 citations

Thrombospondin mediates adherence of CD36+ sickle reticulocytes to endothelial cells

1992 • 166 citations

Interaction of the von Willebrand Factor (vWF) with Collagen

1995 • 160 citations

The role of von Willebrand factor multimers and propeptide cleavage in binding and stabilization of factor VIII.

1991 • 159 citations

Nucleotide sequence of pre-pro-von Willebrand factor cDNA

1986 • 152 citations

Increased adhesion of erythrocytes to components of the extracellular matrix: isolation and characterization of a red blood cell lipid that binds thrombospondin and laminin

1996 • 148 citations

Endothelial cell interactions with sickle cell, sickle trait, mechanically injured, and normal erythrocytes under controlled flow

1987 • 140 citations

Sickle erythrocyte adherence to vascular endothelium. Morphologic correlates and the requirement for divalent cations and collagen-binding plasma proteins.

1985 • 138 citations

Endothelial cell interactions with sickle cell, sickle trait, mechanically injured, and normal erythrocytes under controlled flow

1987 • 128 citations

Thrombospondin interactions with fibronectin and fibrinogen. Mutual inhibition in binding

1984 • 116 citations

Interleukin 1 or endotoxin increases the release of von Willebrand factor from human endothelial cells

1987 • 108 citations

Disturbance of plasma and platelet thrombospondin levels in sickle cell disease

1996 • 105 citations

Peptido-Leukotrienes Are Potent Agonists of von Willebrand Factor Secretion and P-Selectin Surface Expression in Human Umbilical Vein Endothelial Cells

1995 • 105 citations

Cellular attachment to thrombospondin. Cooperative interactions between receptor systems

1991 • 99 citations

Unusually large von willebrand factor multimers preferentially promote young sickle and nonsickle erythrocyte adhesion to endothelial cells

1993 • 99 citations

Sickle erythrocyte-endothelial interactions in microcirculation: the role of von Willebrand factor and implications for vasoocclusion

1993 • 94 citations

Increased circulating endothelial cells in sickle cell crisis

1989 • 93 citations

Diverse mechanisms for cell attachment to platelet thrombospondin

1993 • 90 citations

Adhesion of sickle red blood cells and damage to interleukin-1 beta stimulated endothelial cells under flow in vitro

1996 • 75 citations

Comparison of secretion and subcellular localization of von Willebrand protein with that of thrombospondin and fibronectin in cultured human vascular endothelial cells

1985 • 67 citations

Thrombospondin-platelet interactions. Role of divalent cations, wall shear rate, and platelet membrane glycoproteins.

1993 • 65 citations

Endothelial cell and vascular damage in the sickle cell disorders.

1982 • 64 citations

Demonstration of endothelial adhesion of sickle cells in vivo: a distinct role for deformable sickle cell discocytes

1992 • 60 citations

Glycoprotein IV-independent adhesion of sickle red blood cells to immobilized thrombospondin under flow conditions

1996 • 59 citations

Molecular requirements for the interaction of thrombospondin with thrombin-activated human platelets: modulation of platelet aggregation

1992 • 55 citations

Platelet Adhesion to Multimeric and Dimeric von Willebrand Factor and to Collagen Type III Preincubated With von Willebrand Factor

1996 • 49 citations

Sickle erythrocyte adherence to large vessel and microvascular endothelium under physiologic flow is qualitatively different.

1992 • 47 citations

Radioimmunoassay of human platelet thrombospondin: different patterns of thrombospondin and beta-thromboglobulin antigen secretion and clearance from the circulation.

1985 • 40 citations

Thrombospondin: phenomenology to function.

1989 • 33 citations

Perturbation of cultured human vascular endothelial cells by phorbol ester or thrombin alters the cellular von Willebrand factor distribution

1987 • 32 citations

Interleukin-1 inhibits the synthesis of von Willebrand factor in endothelial cells, which results in a decreased reactivity of their matrix toward platelets.

1987 • 28 citations

Conformational Changes in Adhesive Proteins Modulate Their Adhesive Function

1995 • 26 citations

Subendothelial matrix of cultured endothelial cells contains fully processed high molecular weight von Willebrand factor.

1989 • 23 citations

Interactions between vessel wall and perfused sickled erythrocytes: preliminary observations.

1980 • 10 citations