In vivo control of differentiation of myeloid leukemic cells by recombinant granulocyte-macrophage colony-stimulating factor and interleukin 3

Recombinant Human Granulocyte Colony-Stimulating Factor: Effects on Normal and Leukemic Myeloid Cells

1986 • 1,260 citations

Human GM-CSF: Molecular Cloning of the Complementary DNA and Purification of the Natural and Recombinant Proteins

1985 • 1,253 citations

Normal genetically mosaic mice produced from malignant teratocarcinoma cells.

1975 • 1,175 citations

The Granulocyte-Macrophage Colony-Stimulating Factors

1985 • 1,007 citations

The cloning of normal “Mast” cells in tissue culture

1965 • 886 citations

Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor

1986 • 831 citations

Human IL-3 (multi-CSF): Identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3

1986 • 823 citations

Control of normal cell differentiation and the phenotypic reversion of malignancy in myeloid leukaemia

1978 • 593 citations

Molecular Cloning of a Complementary DNA Encoding Human Macrophage-Specific Colony-Stimulating Factor (CSF-1)

1985 • 542 citations

Differentiation of a cell line of myeloid leukemia

1969 • 520 citations

THE EFFECT OF CELLS TRANSFERRED INTO THE MOUSE BLASTOCYST ON SUBSEQUENT DEVELOPMENT

1974 • 512 citations

Molecular cloning of cDNA for murine interleukin-3

1984 • 485 citations

Fate of teratocarcinoma cells injected into early mouse embryos

1975 • 461 citations

Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte—macrophage colony stimulating factor

1984 • 451 citations

Recombinant human granulocyte colony-stimulating factor. Effects on hematopoiesis in normal and cyclophosphamide-treated primates.

1987 • 428 citations

Stimulation of haematopoiesis in primates by continuous infusion of recombinant human GM-CSF

1986 • 405 citations

Genetic Control of Leucocyte Responses to Endotoxin

1968 • 384 citations

Isolation and characterization of a mouse cDNA clone that expresses mast-cell growth-factor activity in monkey cells.

1984 • 365 citations

Regulation of normal differentiation in mouse and human myeloid leukemic cells by phorbol esters and the mechanism of tumor promotion

1979 • 337 citations

Clonogenic cells in acute myeloblastic leukemia

1986 • 331 citations

Purification of a factor inducing differentiation of mouse myeloid leukemic M1 cells from conditioned medium of mouse fibroblast L929 cells.

1984 • 318 citations

Effects of purified bacterially synthesized murine multi-CSF (IL-3) on hematopoiesis in normal adult mice

1986 • 313 citations

Differentiation of Leukemia Cells to Polymorphonuclear Leukocytes in Patients with Acute Nonlymphocytic Leukemia

1986 • 298 citations

Hemopoietic responses in mice injected with purified recombinant murine GM-CSF.

1987 • 284 citations

In Vitro Induction of Granulocyte Differentiation in Hematopoietic Cells from Leukemic and Non-Leukemic Patients

1970 • 253 citations

Stimulation of hematopoiesis in vivo by recombinant bacterial murine interleukin 3.

1986 • 238 citations

The Molecular Control of Blood Cell Development

1987 • 234 citations

Identification of the human analogue of a regulator that induces differentiation in murine leukaemic cells

1985 • 233 citations

In vivo stimulation of granulopoiesis by recombinant human granulocyte colony-stimulating factor.

1987 • 231 citations

Different Blocks in the Differentiation of Myeloid Leukemic Cells

1974 • 191 citations

Isolation and characterization of the cDNA for murine granulocyte colony-stimulating factor.

1986 • 188 citations

Genomic cloning, characterization, and multilineage growth-promoting activity of human granulocyte-macrophage colony-stimulating factor.

1986 • 164 citations

Control of Normal Differentiation of Myeloid Leukemic Cells to Macrophages and Granulocytes

1973 • 161 citations

Control of lysozyme induction in the differentiation of myeloid leukemic cells

1976 • 148 citations

Formation of Granulocytes and Macrophages in Diffusion Chamber Cultures of Mouse Blood Leucocytes

1970 • 141 citations

Quantitative comparison of in vitro and in vivo methods for the detection of endotoxin.

1971 • 137 citations

Cell differentiation and bypassing of genetic defects in the suppression of malignancy.

1987 • 118 citations

Effect of human recombinant granulocyte colony-stimulating factor on hematopoietic injury in mice induced by 5-fluorouracil

1987 • 114 citations

Separation of different molecular forms of macrophage‐ and granulocyte‐inducing proteins for normal and leukemic myeloid cells

1980 • 113 citations

In vivo inhibition of the development of myeloid leukemia by injection of macrophage‐and granulocyte‐inducing protein

1981 • 110 citations

Participation of myeloid leukaemic cells injected into embryos in haematopoietic differentiation in adult mice

1982 • 110 citations

Expression of murine and human granulocyte-macrophage colony-stimulating factors in S. cerevisiae: mutagenesis of the potential glycosylation sites.

1986 • 105 citations

Synergistic myelopoietic actions in vivo after administration to mice of combinations of purified natural murine colony-stimulating factor 1, recombinant murine interleukin 3, and recombinant murine granulocyte/macrophage colony-stimulating factor.

1987 • 104 citations

In vivo induction of normal differentiation in myeloid leukemia cells

1978 • 103 citations

Isolation and characterization of a T lymphocyte-derived differentiation inducing factor for the myeloid leukemic cell line HL- 60

1984 • 100 citations

Control of normal differentiation of myeloid leukemic cells. VIII. Induction of differentiation to mature granulocytes in mass culture

1975 • 96 citations

Genetic dissection of the control of normal differentiation in myeloid leukemic cells

1977 • 96 citations

Growth, Differentiation and the Reversal of Malignancy

1986 • 89 citations

Indirect induction of differentiation in myeloid leukemic cells by lipid A

1978 • 88 citations

Characterization of macrophage- and granulocyte-inducing proteins for normal and leukemic myeloid cells produced by the Krebs ascites tumor

1981 • 84 citations

Control of normal differentiation of myeloid leukemic cells. XI. Induction of a specific requirement for cell viability and growth during the differentiation of myeloid leukemic cells

1976 • 78 citations

Mechanisms that uncouple growth and differentiation in myeloid leukemia cells: restoration of requirement for normal growth-inducing protein without restoring induction of differentiation-inducing protein.

1982 • 77 citations

Low-dose cytosine arabinoside treatment for acute nonlymphocytic leukemia in elderly patients

1985 • 73 citations

Tumorigenicity of embryonal carcinoma as an assay to study control of malignancy by the murine blastocyst.

1979 • 62 citations

Developmental potential of myeloid leukemia cells injected into midgestation embryos

1984 • 60 citations

Coupling of growth and differentiation in normal myeloid precursors and the breakdown of this coupling in leukemia

1983 • 59 citations

Control of in vivo differentiation of myeloid leukemic cells. iv. inhibition of leukemia development by myeloid differentiation‐inducing protein

1984 • 58 citations

Cell differentiation and therapeutic effect of low doses of cytosine arabinoside in human myeloid leukemia

1984 • 51 citations

Anti‐tumor effects of interferon in mice injected with interferon‐sensitive and interferon‐resistant friend leukemia cells. V. Comparisons with the action of tumor necrosis factor

1986 • 33 citations

Role of different normal hematopoietic regulatory proteins in the differentiation of myeloid leukemic cells

1988 • 31 citations

DNA-binding protein that induces cell differentiation.

1983 • 28 citations

Control of in vivo differentiation of myeloid leukemic cells. III. Regulation By T Lymphocytes And Inflammation

1983 • 21 citations

Review of clinical and haematological response to low‐dose cytosine arabinoside in acute myeloid leukaemia

1987 • 18 citations

Control of in-vivo differentiation of myeloid leukemic cells— V. Regulation by response to antigen

1985 • 15 citations

Regulation of in-vivo differentiation of myeloid leukemic cells by antigen-specific helper T lymphocytes

1986 • 10 citations