Tissue Factor: a Complex Biological Role

Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque.

1989 • 1,233 citations

Selective cellular expression of tissue factor in human tissues. Implications for disorders of hemostasis and thrombosis.

1989 • 1,199 citations

Cell Biology of Atherosclerosis

1995 • 982 citations

Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation.

1977 • 791 citations

The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor

1996 • 726 citations

Role of tissue factor in embryonic blood vessel development

1996 • 693 citations

Activated platelets signal chemokine synthesis by human monocytes.

1996 • 598 citations

P-selectin induces the expression of tissue factor on monocytes.

1994 • 595 citations

The Structural Biology of Expression and Function of Tissue Factor

1991 • 563 citations

Tissue factor controls the balance of angiogenic and antiangiogenic properties of tumor cells in mice.

1994 • 488 citations

Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody

1990 • 369 citations

Fatal embryonic bleeding events in mice lacking tissue factor, the cell-associated initiator of blood coagulation.

1996 • 340 citations

Tissue factor promotes melanoma metastasis by a pathway independent of blood coagulation.

1995 • 303 citations

Initiation and regulation of tissue factor-dependent blood coagulation.

1992 • 287 citations

Targeted disruption of the murine tissue factor gene results in embryonic lethality

1996 • 277 citations

TISSUE FACTOR PATHWAY INHIBITOR AND THE REVISED THEORY OF COAGULATION

1995 • 276 citations

Structural biology of tissue factor, the initiator of thrombogenesis in vivo ¹

1994 • 217 citations

Binding of Human Factor VIIa to Tissue Factor Induces Cytosolic Ca2+ Signals in J82 Cells, Transfected COS-1 Cells, Madin-Darby Canine Kidney Cells and in Human Endothelial Cells Induced to Synthesize Tissue Factor

1995 • 175 citations

Factors IXa and Xa play distinct roles in tissue factor-dependent initiation of coagulation

1995 • 162 citations

Role of the membrane surface in the activation of human coagulation factor X.

1992 • 141 citations

Coagulation Factors VII and X Induce Ca2+ Oscillations in Madin-Darby Canine Kidney Cells Only When Proteolytically Active

1996 • 131 citations

A growth factor-responsive gene of murine BALB/c 3T3 cells encodes a protein homologous to human tissue factor.

1989 • 129 citations

Oxidized LDL enhances lipopolysaccharide-induced tissue factor expression in human adherent monocytes.

1994 • 124 citations

Prevention of arterial reocclusion after thrombolysis with recombinant lipoprotein-associated coagulation inhibitor.

1991 • 123 citations

Granulocytes enhance LPS-induced tissue factor activity in monocytes via an interaction with platelets

1993 • 107 citations

The interaction of human factor VIIa with tissue factor.

1992 • 88 citations

A novel biological effect of platelet factor 4 (PF4): enhancement of LPS-induced tissue factor activity in monocytes

1995 • 74 citations

Cellular Interactions in Hemostasis

1996 • 56 citations

Control of Anticoagulant Therapy

1963 • 51 citations

A GLOBAL VIEW ON THE ROLE OF MONOCYTES AND PLATELETS IN ATHEROGENESIS

1997 • 51 citations

The High Responder Phenomenon: Enhancement of LPS Induced Tissue Factor Activity in Monocytes by Platelets and Granulocytes

1995 • 41 citations

The role of arachidonic acid release and lipoxygenase pathway in lipopolysaccharide-induced thromboplastin activity in monocytes.

1990 • 39 citations

Inhibition of factor IXa and factor Xa by antithrombin III/heparin during factor X activation.

1988 • 37 citations

Procoagulant Human Monocytes Mediate Tissue Factor/Factor VIIa–Dependent Platelet-Thrombus Formation When Exposed to Flowing Nonanticoagulated Human Blood

1995 • 37 citations

CONTROL OF ANTICOAGULANT THERAPY

1960 • 31 citations

The clinical value of tissue factor assays

1995 • 29 citations