A GLOBAL VIEW ON THE ROLE OF MONOCYTES AND PLATELETS IN ATHEROGENESIS

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

Wine, alcohol, platelets, and the French paradox for coronary heart disease

1992 • 3,600 citations

Role of oxidized low density lipoprotein in atherogenesis.

1991 • 2,691 citations

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.

1989 • 1,914 citations

The role of the macrophage in wound repair. A study with hydrocortisone and antimacrophage serum.

1975 • 1,445 citations

The role of oxidized lipoproteins in atherogenesis

1996 • 1,382 citations

Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB

1993 • 1,129 citations

Cell Biology of Atherosclerosis

1995 • 982 citations

PADGEM protein: A receptor that mediates the interaction of activated platelets with neutrophils and monocytes

1989 • 878 citations

Selectins.

1993 • 869 citations

Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells.

1992 • 828 citations

Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent platelets

1992 • 800 citations

Malondialdehyde-Altered Protein Occurs in Atheroma of Watanabe Heritable Hyperlipidemic Rabbits

1988 • 757 citations

P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin.

1995 • 712 citations

A Polymorphism of a Platelet Glycoprotein Receptor as an Inherited Risk Factor for Coronary Thrombosis

1996 • 707 citations

Lysophosphatidylcholine: a chemotactic factor for human monocytes and its potential role in atherogenesis.

1988 • 655 citations

Role of vitamin E in preventing the oxidation of low-density lipoprotein

1991 • 649 citations

Asymptomatic Cardiac Ischemia Pilot (ACIP) Study

1996 • 606 citations

PLASMA LIPID AND LIPOPROTEIN PATTERN IN GREENLANDIC WEST-COAST ESKIMOS

2009 • 601 citations

Activated platelets signal chemokine synthesis by human monocytes.

1996 • 598 citations

P-selectin induces the expression of tissue factor on monocytes.

1994 • 595 citations

Acute vascular effects of estrogen in postmenopausal women.

1994 • 557 citations

Rabbit and human atherosclerotic lesions contain IgG that recognizes epitopes of oxidized LDL.

1994 • 541 citations

Biochemical structural and functional properties of oxidized low-density lipoprotein

1990 • 536 citations

Studies on the pathogenesis of atherosclerosis. I. Adhesion and emigration of mononuclear cells in the aorta of hypercholesterolemic rats.

1983 • 487 citations

Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin.

1995 • 467 citations

Stimulation of lipid peroxidation and hydroxyl-radical generation by the contents of human atherosclerotic lesions

1992 • 463 citations

ENDOTHELIAL-LEUKOCYTE ADHESION MOLECULES IN HUMAN DISEASE

1994 • 461 citations

QUARTAN MALARIAL NEPHROTIC SYNDROME

1972 • 447 citations

Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions.

1990 • 429 citations

Resolution of spontaneous bleeding events but failure of pregnancy in fibrinogen-deficient mice.

1995 • 424 citations

HDL, its enzymes and its potential to influence lipid peroxidation

1995 • 416 citations

Role of tumor necrosis factor-α in disease states and inflammation

1993 • 415 citations

Influence of Sex Hormones on Plasma Endothelin Levels

1993 • 328 citations

Dynamics of leukocyte-platelet adhesion in whole blood

1991 • 312 citations

The pathogenesis of atherosclerosis: An overview

1991 • 306 citations

Modulation of Inflammation and Cytokine Production by Dietary (n-3) Fatty Acids

1996 • 260 citations

Activated platelets induce superoxide anion release by monocytes and neutrophils through P-selectin (CD62).

1993 • 228 citations

Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice.

1994 • 228 citations

Oxidized lipoproteins in atherosclerosis and thrombosis

1994 • 200 citations

On the pathogenesis of atherosclerosis: enzymatic transformation of human low density lipoprotein to an atherogenic moiety.

1995 • 195 citations

Regression or Progression

1996 • 181 citations

Transfer of low density lipoprotein into the arterial wall and risk of atherosclerosis

1996 • 178 citations

The role of platelets in the development and complications of atherosclerosis.

1986 • 178 citations

Increased platelet deposition on atherosclerotic coronary arteries.

1994 • 175 citations

Coronary atherosclerotic plaques with and without thrombus in ischemic heart syndromes: A morphologic, immunohistochemical, and biochemical study

1991 • 160 citations

Lysophosphatidylcholine upregulates the level of heparin-binding epidermal growth factor-like growth factor mRNA in human monocytes.

1994 • 138 citations

The Role of Oxidized Low Density Lipoprotein in Atherogenesis

1996 • 138 citations

Lipid Metabolism, Atherogenesis, and Haemostasis in Eskimos: the Role of the Prostaglandin-3 Family

1979 • 138 citations

Lysophosphatidylcholine Promotes P-Selectin Expression in Platelets and Endothelial Cells

1996 • 127 citations

The contribution of thrombosis to the clinical expression of coronary atherosclerosis

1996 • 118 citations

Postprandial lipoprotein metabolism and atherosclerosis

1995 • 114 citations

Macrophages produce blood coagulation factors

1980 • 113 citations

Granulocytes enhance LPS-induced tissue factor activity in monocytes via an interaction with platelets

1993 • 107 citations

Transcriptional Activation of the Macrophage-Colony Stimulating Factor Gene by Minimally Modified LDL

1995 • 99 citations

Predictors of outcome in acute meningococcal infection in children

1993 • 97 citations

Modified forms of low‐density lipoprotein and atherosclerosis

1993 • 94 citations

Atherogenesis and inflammation.

1993 • 93 citations

Studies on the Pathogenesis of Atherosclerosis [Abridged]

1969 • 91 citations

Dexamethasone-induced suppression of aortic atherosclerosis in cholesterol-fed rabbits. Possible mechanisms.

1993 • 87 citations

Investigation of the oxygenation of phospholipids by the porcine leukocyte and human platelet arachidonate 12‐lipoxygenases

1993 • 86 citations

LPC in oxidized LDL elicits vasocontraction and inhibits endothelium- dependent relaxation

1994 • 82 citations

Effects of dietary supplementation with cod liver oil on monocyte thromboplastin synthesis, coagulation and fibrinolysis

1989 • 78 citations

Different Effects of Estrogen and Progesterone on Experimental Atherosclerosis inFemale Versus Male Rabbits

1996 • 74 citations

A novel biological effect of platelet factor 4 (PF4): enhancement of LPS-induced tissue factor activity in monocytes

1995 • 74 citations

Anti-inflammatory drugs in experimental atherosclerosis

1979 • 73 citations

Alteration of lysophosphatidylcholine content in low density lipoprotein after oxidative modification: relationship to endothelium dependent relaxation

1994 • 69 citations

Production of blood coagulation factory V and tissue thromboplastin by macrophages in vitro

1981 • 68 citations

Lysophosphatidylcholine causes Ca2+ influx, enhanced DNA synthesis and cytotoxicity in cultured vascular smooth muscle cells

1995 • 68 citations

Biology of the impaired endothelium

1991 • 67 citations

Anti-inflammatory drugs in experimental atherosclerosis

1989 • 65 citations

Monocyte-Macrophage Participation in Atherogenesis: Inflammatory Components of Pathogenesis

1986 • 62 citations

Mechanisms Involved in Platelet Vessel Wall Interaction

1995 • 59 citations

The distribution of intimal white blood cells in the normal rabbit aorta

1995 • 59 citations

Relative significance of endothelium and internal elastic lamina in regulating the entry of macromolecules into arteries in vivo.

1994 • 59 citations

Anti-inflammatory drugs in experimental atherosclerosis Part 1. Relative potencies for inhibiting plaque formation

1973 • 58 citations

Pathogenesis of atherosclerosis

1985 • 54 citations

Platelet activating factor enhancement of lipopolysaccharide-induced tissue factor activity in monocytes: requirement of platelets and granulocytes

1992 • 53 citations

Endotoxin-Induced Tissue Factor in Human Monocytes is Dependent upon Protein Kinase C Activation

1993 • 51 citations

n-3 fatty acid ethyl ester administration to healthy subjects and to hypertriglyceridemic patients reduces tissue factor activity in adherent monocytes.

1994 • 51 citations

Effect of marine oils supplementation on coagulation and cellular activation in whole blood

1995 • 51 citations

The effect of inhibitors of free radical generating-enzymes on low-density lipoprotein oxidation by macrophages

1994 • 49 citations

Lipid Transport Aspects of Atherogenesis

1993 • 48 citations

Endothelium-Derived Nitric Oxide, Endothelin, and Platelet Vessel Wall Interaction: Alterations in Hypercholesterolemia and Atherosclerosis

1993 • 47 citations

Hormone replacement therapy reduces the reactivity of monocytes and platelets in whole blood — A beneficial effect on atherogenesis and thrombus formation?

1995 • 47 citations

Immune suppression after acute ethanol ingestion and thermal injury

1991 • 45 citations

Influx, efflux, and accumulation of LDL in normal arterial areas and atherosclerotic lesions of white Carneau pigeons with naturally occurring and cholesterol-aggravated aortic atherosclerosis.

1993 • 44 citations

Role of Selectins in Leukocyte Adhesion to Platelets and Endothelium

1994 • 43 citations

Free radicals and anti-inflammatory drugs.

1986 • 43 citations

The High Responder Phenomenon: Enhancement of LPS Induced Tissue Factor Activity in Monocytes by Platelets and Granulocytes

1995 • 41 citations

3 Platelet and Vessel Wall Interaction and the Genesis of Atherosclerosis

1986 • 41 citations

Oxidized lipoproteins influence gene expression by causing oxidative stress and activating the transcription factor NF-κB

1993 • 40 citations

The role of arachidonic acid release and lipoxygenase pathway in lipopolysaccharide-induced thromboplastin activity in monocytes.

1990 • 39 citations

Endothelial Cell Morphometry of Atherosclerotic Lesions and Flow Profiles at Aortic Bifurcations in Cholesterol Fed Rabbits

1992 • 38 citations

Effects of Dexamethasone on Experimental Atherosclerosis in Cholesterol-fed Rabbits.

1992 • 38 citations

The mandatory role of complement in the endotoxin‐induced synthesis of tissue thromboplastin in blood monocytes

1982 • 35 citations

n-3 fatty acid ethyl ester administration to healthy subjects and to hypertriglyceridemic patients reduces tissue factor activity in adherent monocytes.

1994 • 35 citations

Immune mechanisms in atherosclerosis

1994 • 35 citations

Recruitment and dynamics of leukocytes in the formation of arterial intimal thickening — A comparative study with normo- and hypercholesterolemic rabbits

1993 • 33 citations

The role of arachidonic acid release and lipoxygenase pathway in lipopolysaccharide-induced thromboplastin activity in monocytes

1990 • 31 citations

Regulation of Function and Expression of P-Selectin

1995 • 29 citations

Role of the Vascular Endothelial Cell Antigen System In the Etiology of Atherosclerosis

1985 • 27 citations

Immunologic aspects of Kawasaki disease: Implications for pathogenesis and therapy

1991 • 25 citations

Tissue factor and factor VII messenger RNAs in human alveolar macrophages: effects of breathing ozone

1990 • 23 citations

Lack of ability to synthesize tissue factor by endothelial cells in intact human saphenous veins.

1990 • 21 citations

Thromboxane production in the blood of women increases after menopause whereas tumor necrosis factor is reduced in women compared with men

1993 • 18 citations

Signal Transduction in Atherosclerosis: Second Messengers and Regulation of Cellular Cholesterol Trafficking

1995 • 18 citations

Effects of ethanol on human blood fibrinolysis and coagulation.

1987 • 15 citations

Cytokine production by cholesterol-loaded human peripheral monocyte-macrophages: the effect on fibrinogen mRNA levels in a hepatoma cell-line (HepG2)

1991 • 13 citations

Triphasic response of prostacyclin production in rabbit thoracic aorta in early atherosclerosis

1991 • 13 citations

P‐Selectin Knockout: A Mouse Model for Various Human Diseases

2007 • 12 citations

A surgical model to study in vivo efflux of cholesterol from porcine aorta Evidence for cholesteryl ester transfer through the aortic wall

1989 • 9 citations

Regulation of 12-hydroxyeicosatetraenoic acid synthesis by acetyl-LDL in mouse peritoneal macrophages

1989 • 7 citations

Advances in atherosclerosis.

1995 • 5 citations

Thromboplastin Activity in Blood Monocytes from Oral Contraceptive Users

1986 • 3 citations

The Mediterranean Diet and Cardiovascular Disease

1995 • 2 citations