Somatomedin: Physiological Control and Effects on Cell Proliferation

Handbook of Physiology.

1960 • 10,428 citations

The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin.

1978 • 1,530 citations

A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro. 1956.

1990 • 1,075 citations

Dual control of cell growth by somatomedins and platelet-derived growth factor.

1979 • 926 citations

Estimation of Somatomedin-C Levels in Normals and Patients with Pituitary Disease by Radioimmunoassay

1977 • 858 citations

Somatomedin: Proposed Designation for Sulphation Factor

1972 • 840 citations

Primary structure of human insulin‐like growth factor II

1978 • 776 citations

Induction of DNA synthesis in BALB/c 3T3 cells by serum components: Reevaluation of the commitment process

1977 • 695 citations

Biochemical actions of hormones

1987 • 588 citations

Purification of human platelet-derived growth factor.

1979 • 586 citations

An ordered sequence of events is required before BALB/c-3T3 cells become committed to DNA synthesis

1978 • 472 citations

Growth and Growth Hormone

1968 • 435 citations

Evidence that somatomedin is synthesized by multiple tissues in the fetus

1980 • 434 citations

Platelet factors stimulate fibroblasts and smooth muscle cells quiescent in plasma serum to proliferate.

1976 • 400 citations

ANTIBODY-SUPPRESSIBLE AND NONSUPPRESSIBLE INSULIN-LIKE ACTIVITIES IN HUMAN SERUM AND THEIR PHYSIOLOGIC SIGNIFICANCE. AN INSULIN ASSAY WITH ADIPOSE TISSUE OF INCREASED PRECISION AND SPECIFICITY*

1963 • 399 citations

Insulin‐Like Growth Factors I and II: Some Biological Actions and Receptor Binding Characteristics of Two Purified Constituents of Nonsuppressible Insulin‐Like Activity of Human Serum

1978 • 384 citations

Evaluation of Acromegaly by Radioimmunoassay of Somatomedin-C

1979 • 366 citations

Induction of Immunoreactive Somatomedin C in Human Serum by Growth Hormone: Dose-Response Relationships and Effect on Chromatographic Profiles*

1980 • 356 citations

Direct Demonstration of Separate Receptors for Growth and Metabolic Activities of Insulin and Multiplication-stimulating Activity (an Insulinlike Growth Factor) Using Antibodies to the Insulin Receptor

1980 • 346 citations

A partially purified polypeptide fraction from rat liver cell conditioned medium with multiplication‐stimulating activity for embryo fibroblasts

1973 • 335 citations

Hormonal Control of Immunoreactive Somatomedin Production by Cultured Human Fibroblasts

1981 • 323 citations

Polypeptides with nonsuppressible insulin-like and cell-growth promoting activities in human serum: isolation, chemical characterization, and some biological properties of forms I and II.

1976 • 319 citations

Increased levels of multiplication-stimulating activity, an insulin-like growth factor, in fetal rat serum.

1980 • 313 citations

Characterization of the Insulin and Somatomedin-C Receptors in Human Placental Cell Membranes

1974 • 301 citations

Insulin-like growth factor: a model for tertiary structure accounting for immunoreactivity and receptor binding.

1978 • 282 citations

The Somatomedins: A Family of Insulinlike Hormones under Growth Hormone Control

1974 • 281 citations

Demonstration of Specific Plasma Protein Binding Sites For Somatomedin

1977 • 272 citations

Binding of nonsuppressible insulinlike activity to human serum

1975 • 253 citations

Coordinate control of 3T3 cell proliferation by platelet-derived growth factor and plasma components.

1978 • 252 citations

Purification of somatomedin-C from human plasma: chemical and biological properties, partial sequence analysis, and relationship to other somatomedins

1980 • 250 citations

Plasma somatomedin and growth hormone values in children with protein-calorie malnutrition

1978 • 247 citations

Nonsuppressible insulin-like activity (NSILA) from human serum: Recent accomplishments and their physiologic implications

1978 • 246 citations

The partial purification from calf serum of a fraction with multiplication‐stimulating activity for chicken fibroblasts in cell culture and with non‐suppressible insulin‐like activity

1972 • 209 citations

The Effects of Insulin and Growth Hormone on the Release of Somatomedin by the Isolated Rat Liver

1976 • 209 citations

Growth and maintenance of HeLa cells in serum-free medium supplemented with hormones.

1978 • 208 citations

SULFATION FACTOR ACTIVITY OF SERA FROM PATIENTS WITH PITUITARY DISORDERS*

1959 • 196 citations

The Somatomedin C Binding Protein: Evidence for a Heterologous Subunit Structure*

1980 • 193 citations

Acute and Chronic Estrogen Effects upon Serum Somatomedin Activity, Growth Hormone, and Prolactin in Man

1976 • 192 citations

Growth and diabetes in normal animals treated with pituitary (anterior lobe) diabetogenic extract

1945 • 191 citations

Reduced sulphation factor in undernourished children.

1973 • 190 citations

Control of the Initiation of DNA Synthesis in 3T3 Cells: Serum Factors

1974 • 184 citations

Multiplication‐stimulating activity for chicken embryo fibroblasts from rat liver cell conditioned medium: A family of small polypeptides

1973 • 181 citations

Effects and Binding of Insulin-Like Growth Factor I in the Isolated Soleus Muscle of Lean and Obese Mice: Comparison with Insulin*

1979 • 176 citations

Studies on carcinogenesis by avian sarcoma viruses. VI. Differential multiplication of uninfected and of converted cells in response to insulin

1967 • 174 citations

GROWTH AND GROWTH HORMONE

1959 • 172 citations

Purification and Characterization of Multiplication‐Stimulating Activity

1980 • 171 citations

Inhibition of the Action of Nonsuppressible Insulin-Like Activity on Isolated Rat Fat Cells by Binding to its Carrier Protein

1979 • 170 citations

Release of Somatomedin-Like Activity by Cultured WI-38 Human Fibroblasts*

1980 • 162 citations

Amino-terminal sequences of two polypeptides from human serum with nonsuppressible insulin-like and cell-growth-promoting activities: evidence for structural homology with insulin B chain.

1976 • 161 citations

THE SERUM HALF-LIFE OF SOMATOMEDIN ACTIVITY: EVIDENCE FOR GROWTH HORMONE DEPENDENCE

1976 • 159 citations

EVIDENCE FROM RADIOLIGAND ASSAYS THAT SOMATOMEDIN-C AND INSULIN-LIKE GROWTH FACTOR-I ARE SIMILAR TO EACH OTHER AND DIFFERENT FROM OTHER SOMATOMEDINS1

1980 • 157 citations

Characterization of the binding of multiplication-stimulating activity to a receptor for growth polypeptides in chick embryo fibroblasts.

1977 • 153 citations

Role of the Liver in Regulating Somatomedin Activity: Hormonal Effects on the Synthesis and Release of Insulin-Like Growth Factor and Its Carrier Protein by the Isolated Perfused Rat Liver*

1979 • 150 citations

Specific binding of a somatomedin-like polypeptide in rat serum depends on growth hormone

1976 • 146 citations

Nutrition and Somatomedin. I. Effect of Fasting and Refeeding on Serum Somatomedin Activity and Cartilage Growth Activity in Rats

1976 • 143 citations

OVINE PLACENTAL LACTOGEN INDUCES SOMATOMEDIN: A POSSIBLE ROLE IN FETAL GROWTH

1977 • 140 citations

Further Characterization of Growth Hormone-Dependent Somatomedin-Binding Proteins in Rat Serum and Demonstration of Somatomedin-Binding Proteins Produced by Rat Liver Cells in Culture*

1979 • 138 citations

Synchronous activation of DNA synthesis in hypophysectomized rat cartilage by growth hormone.

1966 • 138 citations

Competitive Binding of Somatomedin to the Insulin Receptors of Adipocytes, Chondrocytes, and Liver Membranes

1972 • 137 citations

The Effect of Hypothyroidism on Growth, Serum Growth Hormone, the Growth Hormone-Dependent Somatomedin, Insulin-Like Growth Factor, and Its Carrier Protein in Rats*

1979 • 137 citations

STUDIES ON THE STATE OF INSULIN IN BLOOD: THE STATE AND TRANSPORT OF INSULIN IN BLOOD¹

1961 • 135 citations

Production of “Sulphation Factor” by the Perfused Liver

1970 • 129 citations

Estradiol treatment of acromegaly Reduction of immunoreactive somatomedin-C and improvement in metabolic status

1980 • 124 citations

FURTHER IMMUNOLOGICAL STUDIES ON THE FORM OF CIRCULATING INSULIN

1962 • 123 citations

DNA Synthesis in Human Fibroblasts: Stimulation by Insulin and by Nonsuppressible Insulin-like Activity (NSILA-S)

1974 • 122 citations

Non-suppressible insulin-like activity of human serum I. Physicochemical properties, extraction and partial purification

1966 • 122 citations

Stimulation of Division of Sparse and Confluent 3T3 Cell Populations by a Fibroblast Growth Factor, Dexamethasone, and Insulin

1974 • 121 citations

Purified multiplication-stimulating activity from rat liver cell conditioned medium: Comparison of biological activities with calf serum, insulin, and somatomedin

1974 • 120 citations

Fibroblasts as an Experimental Tool in Metabolic and Hormone Studies

1973 • 114 citations

QUANTATIVE DETERMINATION OF THE SULPHATION FACTOR ACTIVITY IN HUMAN SERUM

1970 • 112 citations

Somatomedin-C and platelet-derived growth factor stimulate human fibroblast replication

1981 • 111 citations

Nonsuppressible insulin-like activity and thyroid hormones: major pituitary-dependent sulfation factors for chick embryo cartilage.

1976 • 109 citations

The Regulation of Growth by Endocrines

1975 • 109 citations

Suppression of Growth Hormone-dependent Human Serum Sulfation Factor by Estrogen1

1972 • 107 citations

Identification of a Receptor for Somatomedin-Like Polypeptides in Human Fibroblasts*

1977 • 106 citations

Explorations of the Insulinlike and Growth-Promoting Properties of Somatomedin by Membrane Receptor Assays

1975 • 104 citations

Somatomedin-C Receptor Ontogeny and Levels in Porcine Fetal and Human Cord Serum

1976 • 104 citations

Non-suppressible insulin-like activity of human serum

1966 • 103 citations

Glucocorticoid Therapy in Children

1975 • 102 citations

SERUM IMMUNOREACTIVE SOMATOMEDIN-C IS ELEVATED LATE IN PREGNANCY¹

1978 • 102 citations

The Growth Hormone Dependence of a Somatomedin-Binding Protein in Human Serum*

1981 • 101 citations

Characterization of a somatomedin (insulin-like growth factor) synthesized by fetal rat liver organ cultures.

1979 • 100 citations

The Growth-Promoting and Anti-Insulin Actions of Somatotropin

1966 • 100 citations

Immunoreactive Somatomedin A in Human Serum*

1979 • 100 citations

Insulin and non-suppressible insulin-like activity (NSILA-s): Evidence for separate plasma membrane receptor sites

1974 • 99 citations

Serum somatomedin-C in hypopituitarism and in other disorders of growth

1977 • 99 citations

A human fibrosarcoma cell line producing multiplication stimulating activity (MSA)-related peptides

1978 • 97 citations

Sequential addition of platelet factor and plasma to BALB/c 3T3 fibroblast cultures stimulates somatomedin-C binding early in cell cycle.

1980 • 97 citations

The Somatomedins and Their Actions

1978 • 96 citations

Conversion of proline U-C14 to labeled hydroxyproline by rat cartilage in vitro: effects of hypophysectomy, growth hormone, and cortisol.

1962 • 95 citations

NSILA-carrier protein abolishes the action of nonsuppressible insulin-like activity (NSILA-S) on perfused rat heart

1978 • 94 citations

Nonsuppressible insulin-like activity in human serum

1968 • 93 citations

Radioimmunoassay of a Basic Somatomedin: Comparison of Various Assay Techniques and Somatomedin Levels in Various Sera*

1979 • 93 citations

A Serum Fraction with “Sulfation Factor Activity” Stimulatesin VitroIncorporation of Leucine and Sulfate Into Protein-Polysaccharide Complexes, Uridine Into RNA, and Thymidine Into DNA of Costal Cartilage from Hypophysectomized Rats

1970 • 92 citations

Demonstration of a Specific Serum Carrier Protein of Nonsuppressible Insulin-like Activity in Vivo*

1977 • 88 citations

Interaction of multiplication-stimulating activity with chick embryo fibroblasts demonstrates a growth receptor

1976 • 86 citations

Somatomedin C: Restoration in Vivo of Cycle Traverse in G ₀ /G ₁ Blocked Cells of Hypophysectomized Animals

1980 • 83 citations

Purified Human Somatomedin A and Rat Multiplication Stimulating Activity

1978 • 83 citations

In VitroStimulation of Leucine Incorporation Into Muscle and Cartilage Protein by a Serum Fraction with Sulfation Factor Activity: Differentiation of Elfects from Those of Growth Hormone and Insulin

1970 • 82 citations

Identification of two somatomedin a active polypeptides and in vivo effects of a somatomedin a concentrate

1974 • 82 citations

Circulating NSILA-s in Man: Preliminary Studies of Stimuliin Vivoand of Binding to Plasma Components

1975 • 82 citations

SOMATOMEDIN A IN HUMAN SERUM, DETERMINED BY RADIORECEPTOR ASSAY

1976 • 78 citations

Effects of Peptide Anabolic Hormones on Growth of Myoblasts in Culture

1977 • 77 citations

Reduced Serum Somatomedin Activity in Patients with Chronic Liver Disease

1974 • 76 citations

Somatomedin: Inhibition of Adenylate Cyclase Activity in Subcellular Membranes of Various Tissues

1973 • 76 citations

SOME BIOLOGICAL PROPERTIES OF PURIFIED SULFATION FACTOR (SF) FROM HUMAN PLASMA

1971 • 76 citations

AN IMPROVED TECHNIQUE FOR MEASURING SOMATOMEDIN ACTIVITY IN VITRO

1974 • 72 citations

Characterization of the High Molecular Weight Form of Epidermal Growth Factor

1974 • 72 citations

Comparison of [¹²⁵I]Somatomedin A and [¹²⁵I]Somatomedin C Radioreceptor Assays for Somatomedin Peptide Content in Whole and Acid-Chromatographed Plasma*

1978 • 72 citations

Current topics in experimental endocrinology

1971 • 68 citations

Somatomedin and Nutrition. IV. Regulation of Somatomedin Activity and Growth Cartilage Activity by Quantity and Composition of Diet in Rats*

1978 • 67 citations

Influence of Hypophysectomy and Growth Hormone on Cartilage Sulfate Metabolism.

1953 • 67 citations

Hyperprolactinemia Is Associated with Increased Immunoreactive Somatomedin C in Hypopituitarism*

1981 • 67 citations

Human fibroblast conditioned media contains growth‐promoting activities for low density cells

1977 • 66 citations

Proliferation of buffalo rat liver cells in serum-free medium does not depend upon multiplication-stimulating activity (MSA)

1977 • 65 citations

Specific binding of nonsuppressible insulinlike activity to chicken embryo fibroblasts and to a solubilized fibroblast receptor

1975 • 65 citations

Comparison of Somatomedin Activity in Perfusates of Normal and Hypophysectomized Rat Livers With and Without Added Growth Hormone

1976 • 65 citations

INTERACTION OF SOMATOMEDIN-C WITH AN ANTIBODY DIRECTED AGAINST THE SYNTHETIC C-PEPTIDE REGION OF INSULIN-LIKE GROWTH FACTOR-I

1980 • 63 citations

Nutrition and Somatomedin. VI. Somatomedin Activity and Somatomedin Inhibitory Activity in Sera from Normal and Diabetic Rats*

1979 • 62 citations

Determination of Nonsuppressible Insulin-Like Activity in Human Serum by a Sensitive Protein-Binding Assay

1977 • 61 citations

GROWTH-HORMONE DEPENDENCE OF NON-SUPPRESSIBLE INSULIN-LIKE ACTIVITY (NSILA) AND OF NSILA-CARRIER PROTEIN IN RATS

1978 • 57 citations

MAINTENANCE OF SERUM SOMATOMEDIN ACTIVITY IN HYPOPHYSECTOMIZED PREGNANT RATS

1978 • 56 citations

Partial Purification, Characterization, and Assay of a Slightly Acidic Insulin-Like Peptide (ILAs) from Human Plasma*

1978 • 53 citations

Serum Somatomedin Peptides Measured by Somatomedin A Radioreceptor Assay in Chronic Liver Disease

1977 • 51 citations

Nonsuppressible Insulin-Like Activity (NSILA) of Human Serum.

1970 • 51 citations

Current topics in experimental endocrinology

1980 • 50 citations

Stimulation of DNA synthesis, cell multiplication, and ornithine decarboxylase in 3T3 cells by multiplication stimulating activity (MSA)

1976 • 50 citations

Interaction of Somatomedin and a Peptide Inhibitor in Serum of Hypophysectomized and Starved, Pituitary-Intact Rats

1975 • 48 citations

Steroid Hormone Effects on Somatomedin. I. Somatomedin Action in Vitro¹

1975 • 48 citations

Glucocorticoid Inhibition of Sulfate Incorporation by Cartilage of Normal Rats

1975 • 48 citations

Molecular properties of the nerve growth factor secreted by L cells.

1977 • 48 citations

Human somatomedin. Determination, occurrence, biological activity and purification.

1972 • 47 citations

Multiplication-stimulating activity (MSA): a somatomedin-like polypeptide from cultured rat liver cells.

1978 • 47 citations

SOMATOMEDIN PRODUCTION IN NORMAL ADULTS AND CIRRHOTIC PATIENTS

1977 • 47 citations

Nonsuppressible Insulin-Like Activity (NSILA). I. Development of New Sensitive Competitive Protein-Binding Assay for Determination of Serum Levels*

1978 • 47 citations

Studies on Carcinogenesis by Avian Sarcoma Viruses IV

1967 • 47 citations

NON-SUPPRESSIBLE INSULIN-LIKE ACTIVITY AND SULPHATION ACTIVITY IN SERUM EXTRACTS OF NORMAL SUBJECTS, ACROMEGALICS AND PITUITARY DWARFS

1976 • 46 citations

Amino acid, potassium, and sulfate transport and incorporation by embryonic chick cartilage: The mechanism of the stimulatory effects of serum

1966 • 45 citations

Purification of a basic somatomedin, from human plasma Cohn fraction IV-1, with physicochemical and radioimmunoassay similarity to somatomedin-C and insulin-like growth factor

1979 • 45 citations

[6] Measurement of somatomedin by cartilage in Vitro

1975 • 45 citations

Human Somatomedin, the Growth Hormone-Dependent Sulfation Factor, Is Anti-Lipolytic

1972 • 45 citations

EFFECT OF INTRAVENOUS ADMINISTRATION OF HUMAN GROWTH HORMONE ON SULPHATION FACTOR ACTIVITY IN SERUM OF HYPOPITUITARY SUBJECTS

1971 • 45 citations

Sulfation factor: studies of its removal from plasma and metabolic fate in cartilage.

1968 • 44 citations

Effects of Insulin and of NSILA‐S on the Perfused Rat Heart: Glucose Uptake, Lactate Production and Efflux of 3–0‐Methyl Glucose

1975 • 43 citations

Synthesis by cultured hepatocytes of somatomedin and its binding protein

1979 • 42 citations

Contribution of Human Somatomedin Activity to the Serum Growth Requirement of Human Skin Fibroblasts and Chick Embryo Fibroblasts in Culture*

1978 • 42 citations

Stimulation by Insulinin Vitroof Incorporation of (³⁵S)Sulfate and (¹⁴C)Leucine Into Protein-Polysaccharide Complexes, (³H)Uridine Into RNA, and (³H)Thymidine Into DNA of Costal Cartilage from Hypophysectomized Rats

1968 • 40 citations

Mechanism of estrogenic action in acromegaly

1969 • 38 citations

Somatomedin Bioactivity in Serum and Amniotic Fluid during Pregnancy*

1978 • 38 citations

Somatomedin Stimulation of Sulfate Incorporation in Porcine Costal Cartilage Discs¹

1974 • 37 citations

Purification, characterization, and amino acid sequence of rat anaphylatoxin (C3a)

1978 • 37 citations

Effects of Human Somatomedin Preparations on Membrane Transport and Protein Synthesis in the Isolated Rat Diaphragm

1974 • 37 citations

Further Observations on Plasma Somatomedin Activity in Children

1975 • 36 citations

RESPONSE OF ISOLATED RABBIT ARTICULAR AND EPIPHYSEAL CHONDROCYTES TO RAT LIVER SOMATOMEDIN

1975 • 36 citations

Stimulation of ornithine decarboxylase activity in chick fibroblasts by non‐suppressible insulin‐like activity (NSILA), insulin and serum

1976 • 35 citations

Nutrition and Somatomedin. VII. Regulation of Somatomedin Activity by the Perfused Rat Liver*

1980 • 35 citations

Binding of insulin and nonsuppressible insulin-like activity to isolated perfused rat heart muscle

1976 • 34 citations

Somatomedins And Growth

1988 • 33 citations

Insulin, growth, and growth hormone.

1972 • 32 citations

Evidence for the existence in human serum of large molecular weight nonsuppressible insulin‐like activity (NSILA) different from the small molecular weight forms

1978 • 32 citations

RESPONSE OF CHONDROCYTES ISOLATED FROM HUMAN FOETAL CARTILAGE TO PLASMA SOMATOMEDIN ACTIVITY

1978 • 32 citations

Incorporation of³⁵S-sulfate Into Rat Cartilage Explantsin Vitro:Effects of Aging on Responsiveness to Stimulation by Sulfation Factor

1970 • 31 citations

Nonsuppressible Insulin-Like Activity (NSILA).II. Regulation of Serum Concentrations by Growth Hormone and Insulin*

1978 • 31 citations

STUDIES ON SULFATION FACTOR (SF) ACTIVITY OF HUMAN SERUM

1961 • 31 citations

THE LIVER AS A SOURCE OF SOMATOMEDIN

1976 • 30 citations

Induction of tyrosine aminotransferase and amino acid transport in rat hepatoma cells by insulin and the insulin-like growth factor, multiplication-stimulating activity

1980 • 28 citations

Nonsuppressible insulin-like activity of human serum.

1967 • 25 citations

Alteration of Cartilage Glycosaminoglycan Protein Acceptor by Somatomedin and Cortisol

1979 • 25 citations

A RAPID SIMPLIFIED BIOASSAY FOR SOMATOMEDIN

1978 • 24 citations

STUDIES ON SULFATION FACTOR (SF) ACTIVITY OF HUMAN SERUM

1961 • 24 citations

Radioreceptor Assay of Insulin-Like Peptides in Human Plasma: Growth Hormone Dependence and Correlation with Sulfation Activity by Two Bioassays*

1979 • 24 citations

STUDIES ON SULFATION FACTOR (SF) ACTIVITY OF HUMAN SERUM

1961 • 23 citations

Fatty acid inhibition of somatomedin (serum sulfation factor)-stimulated protein and RNA synthesis in embryonic chicken cartilage

1973 • 22 citations

Somatomedin and Growth Hormone in the Newborn

1977 • 22 citations

Isolation and Characterization of a Serum Inhibitor of Cartilage Metabolism *

1974 • 21 citations

Identification and High Yield Purification of Insulin-Like Growth Factors (Nonsuppressible Insulin-Like Activities and Somatomedins) from Human Plasma by Use of Endogenous Binding Proteins*

1979 • 21 citations

Quantitation and Partial Characterization of Nonsuppressible Insulin-like Activity in Serum and Tissue Extracts of the Rat¹

1967 • 20 citations

Growth hormone activity in human pregnancy

1962 • 19 citations

Non-suppressible insulin-like activity of human serum

1971 • 17 citations

Isolation of a growth-stimulating agent from human skin fibroblast cultures

1978 • 16 citations

Purification of bovine somatomedin

1975 • 16 citations

Binding of Somatomedins and Insulin to Plasma Membranes Prepared from Rat and Monkey Tissue

1976 • 16 citations

Lack of Response of Serum Somatomedin to Hyperprolactinemia in Humans*

1980 • 15 citations

Cyclic 3′5′adenosine monophosphate inhibition of sulfation factor activity

1972 • 15 citations

The purification and partial characterization of human somatomedin C.

1980 • 15 citations

Lack of a Simple Relationship Between Endogenous Growth Hormone and NSILA-s Related Peptides

1977 • 14 citations

The somatomedin group of peptide growth factors.

1978 • 14 citations

Mechanism of the Antilipolytic Action of NSILA-S: Inhibition of Adenylate Cyclase Activity in Lipocyte Ghosts

1973 • 14 citations

Effects of Puromycin and Actinomycinin Vitroon Sulfate Incorporation by Cartilage of the Rat and Its Stimulation by Serum Sulfation Factor and Insulin

1967 • 14 citations

Growth hormone activity in human pregnancy

1963 • 14 citations

Further Comparisons of the [¹²⁵I]Somatomedin A and the [¹²⁵I]Somatomedin C Radioreceptor Assays of Somatomedin Peptide*

1979 • 13 citations

Quantitative determination of somatomedin in human serum (35S uptake by embryonic chick cartilage).

1973 • 12 citations

Preliminary Studies of Somatomedin in Vitro and in Vivo in Rats

1975 • 11 citations

Fibroblast Proliferative Activity in the Sera of Growth Hormone Deficient Patients

1973 • 9 citations

The Inhibitory Effect of Hydrocortisone on the Chicken Embryo Cartilage Somatomedin Assay

1976 • 9 citations

Somatomedin A and B: Demonstration of Two Different Somatomedinlike Components in Human Plasma

1975 • 9 citations

Common mechanism of action of somatomedin and insulin on fat cells. Further evidence.

1974 • 8 citations

Glucocorticoid inhibition of glycosaminoglycan biosynthesis: Decrease of protein acceptor

1977 • 7 citations

AGE-DEPENDENT VARIATION IN CARTILAGE RESPONSE TO SOMATOMEDIN

1975 • 5 citations

Nonsuppressible insulin-like activity: biological activity and receptor binding.

1975 • 5 citations